IMP

Process View

Mus musculus

11 genes annotated in mouse

positive regulation of inflammatory response to antigenic stimulus

Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of inflammatory response to antigenic stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of inflammatory response to antigenic stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Tnf	tumor necrosis factor	0.999
Ifng	interferon gamma	0.974
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.967
Il4	interleukin 4	0.947
Icos	inducible T-cell co-stimulator	0.927	Mouse
Cd19	CD19 antigen	0.911
Ikzf1	IKAROS family zinc finger 1	0.908
Igh	immunoglobulin heavy chain complex	0.904
Lta	lymphotoxin A	0.833
Il2rg	interleukin 2 receptor, gamma chain	0.743
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.721
Lyz2	lysozyme 2	0.701
Cxcl13	chemokine (C-X-C motif) ligand 13	0.671
Cd40	CD40 antigen	0.638
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.628	Mouse
Inpp5d	inositol polyphosphate-5-phosphatase D	0.555
Ccr1	chemokine (C-C motif) receptor 1	0.453	Mouse
Pdcd1	programmed cell death 1	0.437
Ccl2	chemokine (C-C motif) ligand 2	0.370
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.355
Fas	Fas (TNF receptor superfamily member 6)	0.337
Il2	interleukin 2	0.271
Cxcr5	chemokine (C-X-C motif) receptor 5	0.249	Mouse
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.244
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.215
Ccl3	chemokine (C-C motif) ligand 3	0.207
Ltb	lymphotoxin B	0.198
Cd40lg	CD40 ligand	0.197	Mouse
Cd4	CD4 antigen	0.194
Ccl4	chemokine (C-C motif) ligand 4	0.189
Ccr6	chemokine (C-C motif) receptor 6	0.183	Mouse
Il7	interleukin 7	0.181
Klrk1	killer cell lectin-like receptor subfamily K, member 1	0.179
Ccr2	chemokine (C-C motif) receptor 2	0.176	Mouse
Apoe	apolipoprotein E	0.174
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.163
Xcr1	chemokine (C motif) receptor 1	0.150	Mouse
Ccr7	chemokine (C-C motif) receptor 7	0.145
Il10	interleukin 10	0.142
Tlr2	toll-like receptor 2	0.139
Klrg1	killer cell lectin-like receptor subfamily G, member 1	0.132
Cd96	CD96 antigen	0.126
Prf1	perforin 1 (pore forming protein)	0.124
Fasl	Fas ligand (TNF superfamily, member 6)	0.112	Mouse
Selp	selectin, platelet	0.108
Batf	basic leucine zipper transcription factor, ATF-like	0.100
Itk	IL2-inducible T-cell kinase	0.099
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.098
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.096
Ptprc	protein tyrosine phosphatase, receptor type, C	0.095
Il1b	interleukin 1 beta	0.081
Il27ra	interleukin 27 receptor, alpha	0.081
Pou2af1	POU domain, class 2, associating factor 1	0.080
Foxp3	forkhead box P3	0.074
Ccr5	chemokine (C-C motif) receptor 5	0.074	Mouse
Cxcr2	chemokine (C-X-C motif) receptor 2	0.071	Mouse
Cd28	CD28 antigen	0.070
Cd7	CD7 antigen	0.068
Il15	interleukin 15	0.068
Cd44	CD44 antigen	0.066
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.065	Mouse
Blk	B lymphoid kinase	0.064
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.063	Mouse
Sh2d2a	SH2 domain protein 2A	0.063
Ccl8	chemokine (C-C motif) ligand 8	0.062
Klrc1	killer cell lectin-like receptor subfamily C, member 1	0.055
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.055
Btk	Bruton agammaglobulinemia tyrosine kinase	0.054
Gzmb	granzyme B	0.053
Ifngr1	interferon gamma receptor 1	0.053
Foxn1	forkhead box N1	0.051
Il6	interleukin 6	0.051
Folr2	folate receptor 2 (fetal)	0.050
Gzmk	granzyme K	0.049
Gpr132	G protein-coupled receptor 132	0.046
Fcer2a	Fc receptor, IgE, low affinity II, alpha polypeptide	0.046
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.045
Ncr1	natural cytotoxicity triggering receptor 1	0.045
Itgal	integrin alpha L	0.045
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.044
Irf4	interferon regulatory factor 4	0.043
Il18rap	interleukin 18 receptor accessory protein	0.042
Tlr4	toll-like receptor 4	0.041
Ccl12	chemokine (C-C motif) ligand 12	0.041
Gbp1	guanylate binding protein 1	0.037
Zap70	zeta-chain (TCR) associated protein kinase	0.037
Cxcr3	chemokine (C-X-C motif) receptor 3	0.036	Mouse
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.034	Mouse
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.033
Igl	immunoglobulin lambda chain complex	0.033
Oprm1	opioid receptor, mu 1	0.032
Cox8c	cytochrome c oxidase, subunit VIIIc	0.032
Il2ra	interleukin 2 receptor, alpha chain	0.031
Art2a-ps	ADP-ribosyltransferase 2a, pseudogene	0.030
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.030
Xcl1	chemokine (C motif) ligand 1	0.030
Tox	thymocyte selection-associated high mobility group box	0.029
Sh2d1a	SH2 domain protein 1A	0.029
Il15ra	interleukin 15 receptor, alpha chain	0.029
Cxcl9	chemokine (C-X-C motif) ligand 9	0.029
Pabpc2	poly(A) binding protein, cytoplasmic 2	0.028
Cd3e	CD3 antigen, epsilon polypeptide	0.028
Ciita	class II transactivator	0.027
Ccr3	chemokine (C-C motif) receptor 3	0.027	Mouse
Il12rb2	interleukin 12 receptor, beta 2	0.026
Myd88	myeloid differentiation primary response gene 88	0.026
Il2rb	interleukin 2 receptor, beta chain	0.026
Slamf1	signaling lymphocytic activation molecule family member 1	0.026
Lck	lymphocyte protein tyrosine kinase	0.026
Prss2	protease, serine, 2	0.026
Socs1	suppressor of cytokine signaling 1	0.025
Id2	inhibitor of DNA binding 2	0.025
Flt3	FMS-like tyrosine kinase 3	0.025
Tg	thyroglobulin	0.024
C3ar1	complement component 3a receptor 1	0.024
Prdm1	PR domain containing 1, with ZNF domain	0.024
Sit1	suppression inducing transmembrane adaptor 1	0.023
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.023
Cd247	CD247 antigen	0.023	Mouse
Ccr9	chemokine (C-C motif) receptor 9	0.023	Mouse
Prg3	proteoglycan 3	0.022
Tlr7	toll-like receptor 7	0.022
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.022
Sele	selectin, endothelial cell	0.022
Wisp2	WNT1 inducible signaling pathway protein 2	0.022
Il18r1	interleukin 18 receptor 1	0.021
Cd5	CD5 antigen	0.021
S1pr4	sphingosine-1-phosphate receptor 4	0.021
Zp2	zona pellucida glycoprotein 2	0.021
Tnfsf8	tumor necrosis factor (ligand) superfamily, member 8	0.021
Crtam	cytotoxic and regulatory T cell molecule	0.021
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.021
Tcstv3	2-cell-stage, variable group, member 3	0.021
Pyhin1	pyrin and HIN domain family, member 1	0.020
Il22	interleukin 22	0.020
Cd22	CD22 antigen	0.020
Vpreb3	pre-B lymphocyte gene 3	0.020
Fcgr1	Fc receptor, IgG, high affinity I	0.020
Mefv	Mediterranean fever	0.020
Spn	sialophorin	0.020
Mpo	myeloperoxidase	0.019
Il10ra	interleukin 10 receptor, alpha	0.019
Cd6	CD6 antigen	0.019
Cxcl10	chemokine (C-X-C motif) ligand 10	0.018
Rel	reticuloendotheliosis oncogene	0.018
Hamp	hepcidin antimicrobial peptide	0.018
Cst7	cystatin F (leukocystatin)	0.017
Mmp9	matrix metallopeptidase 9	0.016
C3	complement component 3	0.016
Tnfrsf17	tumor necrosis factor receptor superfamily, member 17	0.016
Cd180	CD180 antigen	0.016
F9	coagulation factor IX	0.016
Sell	selectin, lymphocyte	0.016
Klra9	killer cell lectin-like receptor subfamily A, member 9	0.016
Card11	caspase recruitment domain family, member 11	0.016
Pdcd1lg2	programmed cell death 1 ligand 2	0.016
Ccl22	chemokine (C-C motif) ligand 22	0.015
Il12a	interleukin 12a	0.015
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.015
Lcn4	lipocalin 4	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.015
Akr1c6	aldo-keto reductase family 1, member C6	0.015
Tnfsf4	tumor necrosis factor (ligand) superfamily, member 4	0.015
Aif1	allograft inflammatory factor 1	0.015
Il1r1	interleukin 1 receptor, type I	0.015
Klrb1c	killer cell lectin-like receptor subfamily B member 1C	0.015
Cd86	CD86 antigen	0.015
Iigp1	interferon inducible GTPase 1	0.015
Bex6	brain expressed gene 6	0.015
Nfatc2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.015
H2-Ob	histocompatibility 2, O region beta locus	0.014
LOC100502924	hypothetical protein LOC100502924	0.014
Itgae	integrin alpha E, epithelial-associated	0.014
Gp9	glycoprotein 9 (platelet)	0.014
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.014
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.013
Cd160	CD160 antigen	0.013
Il1rl1	interleukin 1 receptor-like 1	0.013
Gdf3	growth differentiation factor 3	0.013
Cfh	complement component factor h	0.013
Gcet2	germinal center expressed transcript 2	0.013
Nos2	nitric oxide synthase 2, inducible	0.013
Il17a	interleukin 17A	0.013
Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.013
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.013
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.012
Elf4	E74-like factor 4 (ets domain transcription factor)	0.012
Slamf6	SLAM family member 6	0.012
Ighg	Immunoglobulin heavy chain (gamma polypeptide)	0.012
Rhoh	ras homolog gene family, member H	0.012
Csf3r	colony stimulating factor 3 receptor (granulocyte)	0.012
Elane	elastase, neutrophil expressed	0.012
Esr1	estrogen receptor 1 (alpha)	0.012
Tspo2	translocator protein 2	0.012
Spp1	secreted phosphoprotein 1	0.011
Hcst	hematopoietic cell signal transducer	0.011
Klrb1b	killer cell lectin-like receptor subfamily B member 1B	0.011
Mx2	myxovirus (influenza virus) resistance 2	0.011
Pla2g2d	phospholipase A2, group IID	0.011
Sfpi1	SFFV proviral integration 1	0.011
C1qb	complement component 1, q subcomponent, beta polypeptide	0.010
Fcrla	Fc receptor-like A	0.010	Mouse
Art2b	ADP-ribosyltransferase 2b	0.010
Hdgfl1	hepatoma derived growth factor-like 1	0.010
Prg2	proteoglycan 2, bone marrow	0.010
Cybb	cytochrome b-245, beta polypeptide	0.010
Ctsw	cathepsin W	0.010
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.010
C2	complement component 2 (within H-2S)	0.010
Npy1r	neuropeptide Y receptor Y1	0.010