IMP

Process View

Mus musculus

17 genes annotated in mouse

Multi-species View

apoptotic cell clearance

GO:0043277

The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "apoptotic cell clearance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "apoptotic cell clearance" (in gray)

Name	Description	Probability	Func Analog Organism
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.785
Ctnnb1	catenin (cadherin associated protein), beta 1	0.649
Axl	AXL receptor tyrosine kinase	0.636
Lyz2	lysozyme 2	0.522
Apoe	apolipoprotein E	0.501
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.398
Pten	phosphatase and tensin homolog	0.334
Gsk3b	glycogen synthase kinase 3 beta	0.318	Worm
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.287
Lrp1	low density lipoprotein receptor-related protein 1	0.286
Mapk8ip3	mitogen-activated protein kinase 8 interacting protein 3	0.212
Tlr4	toll-like receptor 4	0.167
Cxcr4	chemokine (C-X-C motif) receptor 4	0.143
Itgb2	integrin beta 2	0.141
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.140
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.107
Cd44	CD44 antigen	0.103
Tyro3	TYRO3 protein tyrosine kinase 3	0.100
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.098
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.098
Ndel1	nuclear distribution gene E-like homolog 1 (A. nidulans)	0.091
Axin1	axin 1	0.088
Npc1	Niemann Pick type C1	0.088
Il6st	interleukin 6 signal transducer	0.079
Ptk2	PTK2 protein tyrosine kinase 2	0.077
Rbl2	retinoblastoma-like 2	0.072
Gab1	growth factor receptor bound protein 2-associated protein 1	0.067
Rxra	retinoid X receptor alpha	0.066
Cav1	caveolin 1, caveolae protein	0.065
Mapk14	mitogen-activated protein kinase 14	0.063
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.062
Dysf	dysferlin	0.062
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.057	Mouse
Tbx3	T-box 3	0.049
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.047
Mmp9	matrix metallopeptidase 9	0.044
Osmr	oncostatin M receptor	0.044
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.044
Lgals1	lectin, galactose binding, soluble 1	0.043
Htt	huntingtin	0.043
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.042
Lgals3	lectin, galactose binding, soluble 3	0.042
Selp	selectin, platelet	0.041
Itgb3	integrin beta 3	0.040
Mapk9	mitogen-activated protein kinase 9	0.040	Fly
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.040
Lrp6	low density lipoprotein receptor-related protein 6	0.039	Mouse
Il1b	interleukin 1 beta	0.038
Mapk8ip2	mitogen-activated protein kinase 8 interacting protein 2	0.038
Il1r1	interleukin 1 receptor, type I	0.036
Apc	adenomatosis polyposis coli	0.035	Worm
Nf2	neurofibromatosis 2	0.035
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.035	Worm
Tmem38b	transmembrane protein 38B	0.035
Il10ra	interleukin 10 receptor, alpha	0.032
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.032	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.032	Worm
Smad3	MAD homolog 3 (Drosophila)	0.032
Ltb	lymphotoxin B	0.031
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.031	Worm
Ccr1	chemokine (C-C motif) receptor 1	0.030
Ccr2	chemokine (C-C motif) receptor 2	0.029
S100a6	S100 calcium binding protein A6 (calcyclin)	0.029
Dck	deoxycytidine kinase	0.029
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.029
Cd9	CD9 antigen	0.029
Cxcl13	chemokine (C-X-C motif) ligand 13	0.028
C3	complement component 3	0.028	Human
Trp63	transformation related protein 63	0.028
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.027
Pacsin1	protein kinase C and casein kinase substrate in neurons 1	0.027
Plxnd1	plexin D1	0.027
Vangl2	vang-like 2 (van gogh, Drosophila)	0.026
Inpp5d	inositol polyphosphate-5-phosphatase D	0.025
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.024
Mdm2	transformed mouse 3T3 cell double minute 2	0.024
Igf1	insulin-like growth factor 1	0.024
Mertk	c-mer proto-oncogene tyrosine kinase	0.024
Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)	0.024	Worm
Cd28	CD28 antigen	0.024
Rdh8	retinol dehydrogenase 8	0.024
Atg13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.023
Csf1	colony stimulating factor 1 (macrophage)	0.023
Dlg4	discs, large homolog 4 (Drosophila)	0.023
Klf5	Kruppel-like factor 5	0.023
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.023
Vcl	vinculin	0.023
Tlr2	toll-like receptor 2	0.022
Pthlh	parathyroid hormone-like peptide	0.022
Ldlr	low density lipoprotein receptor	0.022
Arhgap1	Rho GTPase activating protein 1	0.022
Litaf	LPS-induced TN factor	0.022
Stim2	stromal interaction molecule 2	0.021	Worm
Pou2af1	POU domain, class 2, associating factor 1	0.021
S100a11	S100 calcium binding protein A11 (calgizzarin)	0.021
Ednra	endothelin receptor type A	0.021
Mvp	major vault protein	0.021
Irf5	interferon regulatory factor 5	0.021
Nde1	nuclear distribution gene E homolog 1 (A nidulans)	0.021
Icam1	intercellular adhesion molecule 1	0.020
Rab18	RAB18, member RAS oncogene family	0.020
Smc2	structural maintenance of chromosomes 2	0.020
Stim1	stromal interaction molecule 1	0.019	Worm
Col4a3	collagen, type IV, alpha 3	0.019
App	amyloid beta (A4) precursor protein	0.019
Alox5ap	arachidonate 5-lipoxygenase activating protein	0.019
C3ar1	complement component 3a receptor 1	0.019
Ggta1	glycoprotein galactosyltransferase alpha 1, 3	0.019
Pick1	protein interacting with C kinase 1	0.019
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.019
Ncf1	neutrophil cytosolic factor 1	0.019
Anxa3	annexin A3	0.019
Clic1	chloride intracellular channel 1	0.019
Apaf1	apoptotic peptidase activating factor 1	0.018
Leprot	leptin receptor overlapping transcript	0.018
Tmod3	tropomodulin 3	0.018
S100a10	S100 calcium binding protein A10 (calpactin)	0.018
Adam10	a disintegrin and metallopeptidase domain 10	0.018
Anxa5	annexin A5	0.018	Worm
Ltbr	lymphotoxin B receptor	0.018
Klc1	kinesin light chain 1	0.017
Wls	wntless homolog (Drosophila)	0.017
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.017
Wdr1	WD repeat domain 1	0.017
Klc2	kinesin light chain 2	0.017
Abcg1	ATP-binding cassette, sub-family G (WHITE), member 1	0.017
Gna15	guanine nucleotide binding protein, alpha 15	0.017
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.017
Lrp5	low density lipoprotein receptor-related protein 5	0.016	Mouse
Il18	interleukin 18	0.016
Dnm1	dynamin 1	0.016	Worm
Tmem176a	transmembrane protein 176A	0.016
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.016
Id1	inhibitor of DNA binding 1	0.016
Cxcr5	chemokine (C-X-C motif) receptor 5	0.016
Pstpip1	proline-serine-threonine phosphatase-interacting protein 1	0.016
Ric8	resistance to inhibitors of cholinesterase 8 homolog (C. elegans)	0.016
Hcls1	hematopoietic cell specific Lyn substrate 1	0.016
Tmpo	thymopoietin	0.016
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.015	Worm
Rdh10	retinol dehydrogenase 10 (all-trans)	0.015
Epn1	epsin 1	0.015
Tbxas1	thromboxane A synthase 1, platelet	0.015
Acvr1	activin A receptor, type 1	0.015
Tnfsf14	tumor necrosis factor (ligand) superfamily, member 14	0.015	Fly
Sept1	septin 1	0.015
Epas1	endothelial PAS domain protein 1	0.015
Cd96	CD96 antigen	0.015
Sri	sorcin	0.015
Grb2	growth factor receptor bound protein 2	0.015
Mecp2	methyl CpG binding protein 2	0.015
Tgm2	transglutaminase 2, C polypeptide	0.015	Human
Nfib	nuclear factor I/B	0.015
Tnf	tumor necrosis factor	0.014	Fly
C2	complement component 2 (within H-2S)	0.014
Rbl1	retinoblastoma-like 1 (p107)	0.014
Spry2	sprouty homolog 2 (Drosophila)	0.014
Il1rn	interleukin 1 receptor antagonist	0.014
Gnrh1	gonadotropin releasing hormone 1	0.014
Ptges	prostaglandin E synthase	0.014
Capzb	capping protein (actin filament) muscle Z-line, beta	0.014
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.014
Bmp1	bone morphogenetic protein 1	0.014
Dok1	docking protein 1	0.014
Itgal	integrin alpha L	0.014	Mouse Fly
Sh3bgrl	SH3-binding domain glutamic acid-rich protein like	0.014
Lama5	laminin, alpha 5	0.013
Anxa4	annexin A4	0.013	Worm
Ifng	interferon gamma	0.013
Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	0.013
En1	engrailed 1	0.013
Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	0.013
Rarg	retinoic acid receptor, gamma	0.013
Serpinb6a	serine (or cysteine) peptidase inhibitor, clade B, member 6a	0.013
Emp1	epithelial membrane protein 1	0.013
Pofut1	protein O-fucosyltransferase 1	0.013
Il7	interleukin 7	0.013
Spnb2	spectrin beta 2	0.013
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.013
Myd88	myeloid differentiation primary response gene 88	0.013
Zeb1	zinc finger E-box binding homeobox 1	0.013
Msn	moesin	0.013
Lbr	lamin B receptor	0.013
Ctsw	cathepsin W	0.013
Smad4	MAD homolog 4 (Drosophila)	0.013
Tox	thymocyte selection-associated high mobility group box	0.013
Id2	inhibitor of DNA binding 2	0.012
Sod3	superoxide dismutase 3, extracellular	0.012
Cfh	complement component factor h	0.012
Sirpa	signal-regulatory protein alpha	0.012
Cstb	cystatin B	0.012
Dsc3	desmocollin 3	0.012
Notch2	Notch gene homolog 2 (Drosophila)	0.012
Nfam1	Nfat activating molecule with ITAM motif 1	0.012
Prnp	prion protein	0.012
Mpdz	multiple PDZ domain protein	0.012
Hif1a	hypoxia inducible factor 1, alpha subunit	0.012
Fes	feline sarcoma oncogene	0.012
Gna12	guanine nucleotide binding protein, alpha 12	0.012
Ubd	ubiquitin D	0.012
Lta	lymphotoxin A	0.012	Fly
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.012
Fgfr3	fibroblast growth factor receptor 3	0.012	Worm
Jak3	Janus kinase 3	0.012
Sykb	spleen tyrosine kinase	0.011	Fly
Rac1	RAS-related C3 botulinum substrate 1	0.011
Fn1	fibronectin 1	0.011
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.011	Fly
Zeb2	zinc finger E-box binding homeobox 2	0.011
Calu	calumenin	0.011
Casp1	caspase 1	0.011	Worm
Cd38	CD38 antigen	0.011
Ikbkg	inhibitor of kappaB kinase gamma	0.011
Col4a2	collagen, type IV, alpha 2	0.011
Runx1	runt related transcription factor 1	0.011
Pdgfb	platelet derived growth factor, B polypeptide	0.011
Casp3	caspase 3	0.011
Il2rb	interleukin 2 receptor, beta chain	0.011
Gnptab	N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits	0.011
Pola1	polymerase (DNA directed), alpha 1	0.011
Lrp2	low density lipoprotein receptor-related protein 2	0.011	Mouse
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.011
Plxna1	plexin A1	0.011
Nckap1l	NCK associated protein 1 like	0.011
Tgfbr1	transforming growth factor, beta receptor I	0.011
Lamc1	laminin, gamma 1	0.010
Il6	interleukin 6	0.010
Xiap	X-linked inhibitor of apoptosis	0.010
Rasal3	RAS protein activator like 3	0.010
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.010
Orai1	ORAI calcium release-activated calcium modulator 1	0.010
Ptch1	patched homolog 1	0.010
Ccl5	chemokine (C-C motif) ligand 5	0.010
Adam8	a disintegrin and metallopeptidase domain 8	0.010
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.010
Cycs	cytochrome c, somatic	0.010
Nono	non-POU-domain-containing, octamer binding protein	0.010
Myadm	myeloid-associated differentiation marker	0.010
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.010