IMP

Process View

Mus musculus

17 genes annotated in mouse

Multi-species View

triglyceride biosynthetic process

GO:0019432

The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "triglyceride biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "triglyceride biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
Pparg	peroxisome proliferator activated receptor gamma	0.970
Apoe	apolipoprotein E	0.951
Dab1	disabled homolog 1 (Drosophila)	0.950
Pnpla2	patatin-like phospholipase domain containing 2	0.851
Scd1	stearoyl-Coenzyme A desaturase 1	0.822
Lef1	lymphoid enhancer binding factor 1	0.791	Mouse
Tcf7	transcription factor 7, T-cell specific	0.783	Mouse
Cav1	caveolin 1, caveolae protein	0.543
Cidec	cell death-inducing DFFA-like effector c	0.492
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.451
Ghr	growth hormone receptor	0.436
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.420
Abhd5	abhydrolase domain containing 5	0.407
Lpin1	lipin 1	0.346
Lep	leptin	0.338
Lrp1	low density lipoprotein receptor-related protein 1	0.302
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.291
Nos3	nitric oxide synthase 3, endothelial cell	0.278
Fasn	fatty acid synthase	0.271
Irs2	insulin receptor substrate 2	0.243
Lpl	lipoprotein lipase	0.242
Pcx	pyruvate carboxylase	0.235
Adipoq	adiponectin, C1Q and collagen domain containing	0.228
Adipor2	adiponectin receptor 2	0.205
Srf	serum response factor	0.194
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.186
Sqle	squalene epoxidase	0.180
Ahr	aryl-hydrocarbon receptor	0.176
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.171
Lrp8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor	0.162	Mouse
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.155
Dhcr7	7-dehydrocholesterol reductase	0.134
Flt1	FMS-like tyrosine kinase 1	0.131
Tlr4	toll-like receptor 4	0.130
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.129
Npc1	Niemann Pick type C1	0.120
Fabp4	fatty acid binding protein 4, adipocyte	0.118
Mvd	mevalonate (diphospho) decarboxylase	0.116
Reln	reelin	0.106
Dhcr24	24-dehydrocholesterol reductase	0.097
Lipe	lipase, hormone sensitive	0.091
Ldlr	low density lipoprotein receptor	0.089
Lss	lanosterol synthase	0.072
Insr	insulin receptor	0.071
Apoc1	apolipoprotein C-I	0.069
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.068
Hmgcs1	3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1	0.066
Fas	Fas (TNF receptor superfamily member 6)	0.066
Notch2	Notch gene homolog 2 (Drosophila)	0.065
Gpd1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.062
Tbx3	T-box 3	0.062
Acly	ATP citrate lyase	0.061
Psen1	presenilin 1	0.060
Cyp51	cytochrome P450, family 51	0.059
Hsd11b1	hydroxysteroid 11-beta dehydrogenase 1	0.059
Orm1	orosomucoid 1	0.056
Acsl1	acyl-CoA synthetase long-chain family member 1	0.056
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.053
Wasf2	WAS protein family, member 2	0.050
Adhfe1	alcohol dehydrogenase, iron containing, 1	0.050
Irs1	insulin receptor substrate 1	0.050
Vldlr	very low density lipoprotein receptor	0.048	Mouse
Sc4mol	sterol-C4-methyl oxidase-like	0.048
Lrp5	low density lipoprotein receptor-related protein 5	0.048
Hp	haptoglobin	0.048
Plin1	perilipin 1	0.047
Aacs	acetoacetyl-CoA synthetase	0.046
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.044
Car3	carbonic anhydrase 3	0.044
Adrb3	adrenergic receptor, beta 3	0.044
Stard4	StAR-related lipid transfer (START) domain containing 4	0.043
Ccl2	chemokine (C-C motif) ligand 2	0.042
Axin2	axin2	0.042
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.040
Plin4	perilipin 4	0.040
Scd2	stearoyl-Coenzyme A desaturase 2	0.039
Kiss1	KiSS-1 metastasis-suppressor	0.039
Il1r1	interleukin 1 receptor, type I	0.038
Cfd	complement factor D (adipsin)	0.038
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.037
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.036
Por	P450 (cytochrome) oxidoreductase	0.036
Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	0.035
Gjb2	gap junction protein, beta 2	0.035
Adig	adipogenin	0.034
Ephx2	epoxide hydrolase 2, cytoplasmic	0.034
Acaa2	acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)	0.034
G0s2	G0/G1 switch gene 2	0.033
Dusp8	dual specificity phosphatase 8	0.033
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.033
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.032
Ncoa3	nuclear receptor coactivator 3	0.032
Cidea	cell death-inducing DNA fragmentation factor, alpha subunit-like effector A	0.032
Ctnna1	catenin (cadherin associated protein), alpha 1	0.032
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.032
Trf	transferrin	0.031
Tlr2	toll-like receptor 2	0.031
Dgat2	diacylglycerol O-acyltransferase 2	0.031
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.030
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.030
Thrsp	thyroid hormone responsive SPOT14 homolog (Rattus)	0.029
Ppap2b	phosphatidic acid phosphatase type 2B	0.029
Nfib	nuclear factor I/B	0.029
C3	complement component 3	0.029	Human
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.028
Ppara	peroxisome proliferator activated receptor alpha	0.028
Hsd17b7	hydroxysteroid (17-beta) dehydrogenase 7	0.028
Gsk3b	glycogen synthase kinase 3 beta	0.028
Nrg4	neuregulin 4	0.028
Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	0.027
Bmp7	bone morphogenetic protein 7	0.026
Tgif2	TGFB-induced factor homeobox 2	0.026
Pias4	protein inhibitor of activated STAT 4	0.026
Ptprf	protein tyrosine phosphatase, receptor type, F	0.026
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.025
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.025
Lpcat3	lysophosphatidylcholine acyltransferase 3	0.025
Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1	0.024
Amy1	amylase 1, salivary	0.024
Notch1	Notch gene homolog 1 (Drosophila)	0.024
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.024
Ces1d	carboxylesterase 1D	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.023
Acat2	acetyl-Coenzyme A acetyltransferase 2	0.023
Lepr	leptin receptor	0.023
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.023
Alas1	aminolevulinic acid synthase 1	0.023
Lcat	lecithin cholesterol acyltransferase	0.023
Tkt	transketolase	0.023
Apoa1	apolipoprotein A-I	0.022
Lgals12	lectin, galactose binding, soluble 12	0.022
Tmem45b	transmembrane protein 45b	0.022
Bcl11a	B-cell CLL/lymphoma 11A (zinc finger protein)	0.022
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.022
Gys2	glycogen synthase 2	0.022
9530008L14Rik	RIKEN cDNA 9530008L14 gene	0.021
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.021
Cox8b	cytochrome c oxidase, subunit VIIIb	0.020
Retn	resistin	0.020
Otx1	orthodenticle homolog 1 (Drosophila)	0.020
Slc12a6	solute carrier family 12, member 6	0.020
Idi1	isopentenyl-diphosphate delta isomerase	0.020
Prlr	prolactin receptor	0.019
Htt	huntingtin	0.019
Agtr1a	angiotensin II receptor, type 1a	0.019
Rxrg	retinoid X receptor gamma	0.019
Ptpn23	protein tyrosine phosphatase, non-receptor type 23	0.019
Fzd4	frizzled homolog 4 (Drosophila)	0.018
Clock	circadian locomotor output cycles kaput	0.018
Slc25a28	solute carrier family 25, member 28	0.018
Id3	inhibitor of DNA binding 3	0.018
Gsta3	glutathione S-transferase, alpha 3	0.018
Pygl	liver glycogen phosphorylase	0.018
Sox11	SRY-box containing gene 11	0.018
Pim3	proviral integration site 3	0.018
Samd4b	sterile alpha motif domain containing 4B	0.018
Pvrl2	poliovirus receptor-related 2	0.018
Fads2	fatty acid desaturase 2	0.018
Spen	SPEN homolog, transcriptional regulator (Drosophila)	0.018
Pon1	paraoxonase 1	0.018
Tcn2	transcobalamin 2	0.018
Sf1	splicing factor 1	0.017
Auts2	autism susceptibility candidate 2	0.017
Gba	glucosidase, beta, acid	0.017
Plin2	perilipin 2	0.017
Maz	MYC-associated zinc finger protein (purine-binding transcription factor)	0.017
Ctnnd1	catenin (cadherin associated protein), delta 1	0.016
Celsr1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.016
Klf15	Kruppel-like factor 15	0.016
Pex11a	peroxisomal biogenesis factor 11 alpha	0.016
Plxna2	plexin A2	0.016
Acp5	acid phosphatase 5, tartrate resistant	0.016
Pcyt2	phosphate cytidylyltransferase 2, ethanolamine	0.016
Sertad2	SERTA domain containing 2	0.016
Rims2	regulating synaptic membrane exocytosis 2	0.016
Pgm2	phosphoglucomutase 2	0.016
Acox1	acyl-Coenzyme A oxidase 1, palmitoyl	0.016
Txnip	thioredoxin interacting protein	0.015
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.015
Numb	numb gene homolog (Drosophila)	0.015
Dpyd	dihydropyrimidine dehydrogenase	0.015
Myb	myeloblastosis oncogene	0.015
Thra	thyroid hormone receptor alpha	0.015
Nr1h3	nuclear receptor subfamily 1, group H, member 3	0.015	Human
Plbd1	phospholipase B domain containing 1	0.015
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.015
Homer1	homer homolog 1 (Drosophila)	0.015
Zic2	zinc finger protein of the cerebellum 2	0.015
Fah	fumarylacetoacetate hydrolase	0.015
Tbc1d22b	TBC1 domain family, member 22B	0.015
Crat	carnitine acetyltransferase	0.015
1100001G20Rik	RIKEN cDNA 1100001G20 gene	0.015
Fgf13	fibroblast growth factor 13	0.015
Slc22a3	solute carrier family 22 (organic cation transporter), member 3	0.015
Lipa	lysosomal acid lipase A	0.015
Sept5	septin 5	0.015
Plcd1	phospholipase C, delta 1	0.014
Aifm2	apoptosis-inducing factor, mitochondrion-associated 2	0.014
Cd36	CD36 antigen	0.014	Mouse
Ano10	anoctamin 10	0.014
E2f4	E2F transcription factor 4	0.014
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.014
Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	0.014
Mlxipl	MLX interacting protein-like	0.014
Cdk11b	cyclin-dependent kinase 11B	0.014
Nckap5l	NCK-associated protein 5-like	0.014
Epha4	Eph receptor A4	0.014
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.014
Ppp6r1	protein phosphatase 6, regulatory subunit 1	0.014
Prkce	protein kinase C, epsilon	0.014
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.014
Esr1	estrogen receptor 1 (alpha)	0.014
Sc5d	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae)	0.014
Tmbim6	transmembrane BAX inhibitor motif containing 6	0.014
Epas1	endothelial PAS domain protein 1	0.014
Rora	RAR-related orphan receptor alpha	0.014
Ces1f	carboxylesterase 1F	0.014
Lrp4	low density lipoprotein receptor-related protein 4	0.014
Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	0.013
Stim1	stromal interaction molecule 1	0.013
Zfpl1	zinc finger like protein 1	0.013
Slc22a23	solute carrier family 22, member 23	0.013
Trim8	tripartite motif-containing 8	0.013
Adrb1	adrenergic receptor, beta 1	0.013
Ctsl	cathepsin L	0.013
Furin	furin (paired basic amino acid cleaving enzyme)	0.013
Fam19a5	family with sequence similarity 19, member A5	0.013
Clcn6	chloride channel 6	0.013
Rasd1	RAS, dexamethasone-induced 1	0.013
Lmf1	lipase maturation factor 1	0.013
Sfxn1	sideroflexin 1	0.013
Abl2	v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)	0.013
Lass2	LAG1 homolog, ceramide synthase 2	0.012
Pde10a	phosphodiesterase 10A	0.012
Pura	purine rich element binding protein A	0.012
Mrap	melanocortin 2 receptor accessory protein	0.012
Rfwd2	ring finger and WD repeat domain 2	0.012
Aco1	aconitase 1	0.012
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.012
Mgll	monoglyceride lipase	0.012
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.012
Aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.012
Mosc1	MOCO sulphurase C-terminal domain containing 1	0.012
Fam100a	family with sequence similarity 100, member A	0.012
Bglap	bone gamma carboxyglutamate protein	0.012
Ninj1	ninjurin 1	0.012
Pfkfb1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.012
Osbpl6	oxysterol binding protein-like 6	0.012
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.012
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.012
Acacb	acetyl-Coenzyme A carboxylase beta	0.012
Angptl4	angiopoietin-like 4	0.012
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.012
Plekhh3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3	0.012
Sult1a1	sulfotransferase family 1A, phenol-preferring, member 1	0.012
Siah1a	seven in absentia 1A	0.012
Hipk2	homeodomain interacting protein kinase 2	0.012
Bpnt1	bisphosphate 3'-nucleotidase 1	0.012
Celsr3	cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)	0.012
Meis3	Meis homeobox 3	0.011
Foxo1	forkhead box O1	0.011
Gata6	GATA binding protein 6	0.011
Ar	androgen receptor	0.011
Grip1	glutamate receptor interacting protein 1	0.011
Apba3	amyloid beta (A4) precursor protein-binding, family A, member 3	0.011
Src	Rous sarcoma oncogene	0.011
Gtpbp6	GTP binding protein 6 (putative)	0.011
Prkca	protein kinase C, alpha	0.011
Hspa2	heat shock protein 2	0.011
Pcdh1	protocadherin 1	0.011
Slc36a2	solute carrier family 36 (proton/amino acid symporter), member 2	0.011
Eomes	eomesodermin homolog (Xenopus laevis)	0.011
Mogat1	monoacylglycerol O-acyltransferase 1	0.011
Plin5	perilipin 5	0.011
Klc2	kinesin light chain 2	0.011
Fmo1	flavin containing monooxygenase 1	0.011
Zfp423	zinc finger protein 423	0.011
2010003K11Rik	RIKEN cDNA 2010003K11 gene	0.011
Pou3f1	POU domain, class 3, transcription factor 1	0.011
Lmtk2	lemur tyrosine kinase 2	0.011
Sbf1	SET binding factor 1	0.011
Gsk3a	glycogen synthase kinase 3 alpha	0.011
Art3	ADP-ribosyltransferase 3	0.011
Insig1	insulin induced gene 1	0.011
Ncor2	nuclear receptor co-repressor 2	0.011
Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.011
Ppargc1b	peroxisome proliferative activated receptor, gamma, coactivator 1 beta	0.011
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.011
Acaca	acetyl-Coenzyme A carboxylase alpha	0.011
Nf2	neurofibromatosis 2	0.011
Actn4	actinin alpha 4	0.011
Tax1bp3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.011
Scaf1	SR-related CTD-associated factor 1	0.011
Dab2ip	disabled homolog 2 (Drosophila) interacting protein	0.011
Mecom	MDS1 and EVI1 complex locus	0.011
Aqp7	aquaporin 7	0.011
Psmd11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.011
Hip1r	huntingtin interacting protein 1 related	0.011
Wiz	widely-interspaced zinc finger motifs	0.011
Dag1	dystroglycan 1	0.011
Cry1	cryptochrome 1 (photolyase-like)	0.011
Ptk2	PTK2 protein tyrosine kinase 2	0.011
Sdccag3	serologically defined colon cancer antigen 3	0.010
Med1	mediator complex subunit 1	0.010
Rab4b	RAB4B, member RAS oncogene family	0.010
Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	0.010
Hmg20b	high mobility group 20 B	0.010
Fbn1	fibrillin 1	0.010
Nefm	neurofilament, medium polypeptide	0.010
Bhlhe40	basic helix-loop-helix family, member e40	0.010
Itm2c	integral membrane protein 2C	0.010
Gpt	glutamic pyruvic transaminase, soluble	0.010
Smoc1	SPARC related modular calcium binding 1	0.010
Paqr9	progestin and adipoQ receptor family member IX	0.010
Sav1	salvador homolog 1 (Drosophila)	0.010
Cp	ceruloplasmin	0.010
Hbb-b2	hemoglobin, beta adult minor chain	0.010