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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of anterior neural cell fate commitment of the neural plate"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of anterior neural cell fate commitment of the neural plate" (in gray)

Name	Description	Probability	Func Analog Organism
wnt4a	wingless-type MMTV integration site family, member 4a	0.999	Zebrafish
tbx1	T-box 1	0.999
wnt10a	wingless-type MMTV integration site family, member 10a	0.993	Zebrafish
wnt1	wingless-type MMTV integration site family, member 1	0.993	Zebrafish
wnt3a	wingless-type MMTV integration site family, member 3A	0.979	Zebrafish
hnf1ba	HNF1 homeobox Ba	0.938
fgf3	fibroblast growth factor 3	0.936
gli1	GLI-Kruppel family member 1	0.893
col11a2	collagen type XI alpha-2	0.885
hoxd4a	homeo box D4a	0.867
wnt8b	wingless-type MMTV integration site family, member 8b	0.827
wnt10b	wingless-type MMTV integration site family, member 10b	0.815	Zebrafish
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.774
twist3	twist3	0.772
bmp2a	bone morphogenetic protein 2a	0.764
wnt9b	wingless-type MMTV integration site family, member 9B	0.764	Zebrafish
wls	wntless homolog (Drosophila)	0.745
bmp4	bone morphogenetic protein 4	0.722
ptch2	patched 2	0.687
wnt9a	wingless-type MMTV integration site family, member 9A	0.680	Zebrafish
flh	floating head	0.672
wnt2	wingless-type MMTV integration site family member 2	0.645	Zebrafish
wnt3	wingless-type MMTV integration site family, member 3	0.630	Zebrafish
pdlim7	PDZ and LIM domain 7	0.628
fgf17	fibroblast growth factor 17	0.610
twist1a	twist1a	0.606
dharma	dharma	0.587
pax7a	paired box gene 7a	0.577
zfyve26	zinc finger, FYVE domain containing 26	0.576
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.522	Zebrafish
sfrp1a	secreted frizzled-related protein 1a	0.461
grem1a	gremlin 1 homolog a, cysteine knot superfamily (Xenopus laevis)	0.459
scube2	signal peptide, CUB domain, EGF-like 2	0.410
ptch1	patched 1	0.379
lef1	lymphocyte enhancer binding factor 1	0.364
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.363	Zebrafish
ndr2	nodal-related 2	0.362
fgf8a	fibroblast growth factor 8 a	0.353
gli2b	GLI-Kruppel family member GLI2b	0.325
dkk1b	dickkopf 1b	0.321
dusp6	dual specificity phosphatase 6	0.311
gbx2	gastrulation brain homeo box 2	0.304
wnt16	wingless-type MMTV integration site family, member 16	0.291
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.281	Zebrafish
eng2a	engrailed 2a	0.278
satb2	SATB homeobox 2	0.265
wnt11r	wingless-type MMTV integration site family, member 11, related	0.232	Zebrafish
ntn1b	netrin 1b	0.228
sox2	SRY-box containing gene 2	0.228
fgf4	fibroblast growth factor 4	0.223
dbx1a	developing brain homeobox 1a	0.222
zbtb4	zinc finger and BTB domain containing 4	0.209
wnt4b	wingless-type MMTV integration site family, member 4b	0.207	Zebrafish
ihha	Indian hedgehog homolog a	0.205
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.204
hapln1a	hyaluronan and proteoglycan link protein 1a	0.201
si:dkey-273o13.1	si:dkey-273o13.1	0.195
runx2b	runt-related transcription factor 2b	0.192
mll	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.191
hoxa13b	homeo box A13b	0.186
lft2	lefty2	0.180
pdlim3b	PDZ and LIM domain 3b	0.177
foxb1.2	forkhead box B1.2	0.170
shha	sonic hedgehog a	0.169
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.169
hmx4	H6 family homeobox 4	0.167
sfrp5	secreted frizzled-related protein 5	0.164
pcdh18b	protocadherin 18b	0.160
epha4a	eph receptor A4a	0.159
myod1	myogenic differentiation 1	0.157
msxc	muscle segment homeobox C	0.157
zgc:171802	zgc:171802	0.154
lratb	lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)	0.151
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.149
frem3	Fras1 related extracellular matrix 3	0.145
cdkn1c	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.140
tbx18	T-box 18	0.136
lhx2b	LIM homeobox 2b	0.135
map2k7	mitogen-activated protein kinase kinase 7	0.134
map2k4b	mitogen-activated protein kinase kinase 4b	0.129
shhb	sonic hedgehog b	0.123
wnt8a	wingless-type MMTV integration site family, member 8a	0.123	Zebrafish
ippk	inositol 1,3,4,5,6-pentakisphosphate 2-kinase	0.122
map2k4a	mitogen-activated protein kinase kinase 4a	0.122
wnt5b	wingless-type MMTV integration site family, member 5b	0.119	Zebrafish
ntla	no tail a	0.118
pou5f1	POU domain, class 5, transcription factor 1	0.117
bmp2b	bone morphogenetic protein 2b	0.117
admp	anti-dorsalizing morphogenic protein	0.117
chd	chordin	0.114
rbpja	recombination signal binding protein for immunoglobulin kappa J region a	0.109
fgf10a	fibroblast growth factor 10a	0.106
tbx5a	T-box 5a	0.106
ephb4b	eph receptor B4b	0.102
hoxa2b	homeo box A2b	0.099
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.098
cdx4	caudal type homeo box transcription factor 4	0.098
sfrp1b	secreted frizzled-related protein 1b	0.098
tll1	tolloid-like 1	0.097
sb:cb81	sb:cb81	0.096
tfpi2	tissue factor pathway inhibitor 2	0.096
dld	deltaD	0.094
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.094
chrna4	cholinergic receptor, nicotinic, alpha 4	0.094
twist1b	twist1b	0.092
foxd3	forkhead box D3	0.091
rest	RE1-silencing transcription factor	0.090
nkx3.2	NK3 homeobox 2	0.090
fbn2b	fibrillin 2b	0.089
ldb2a	LIM-domain binding factor 2a	0.089
vent	ventral expressed homeobox	0.087
oep	one-eyed pinhead	0.087
sox11b	SRY-box containing gene 11b	0.086
snai1b	snail homolog 1b (Drosophila)	0.086
pth2	parathyroid hormone 2	0.085
hoxb1a	homeo box B1a	0.083
ism1	isthmin 1	0.081
sox4b	SRY-box containing gene 4b	0.080
mapk14a	mitogen-activated protein kinase 14a	0.080
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.078
myf5	myogenic factor 5	0.077
gyltl1b	glycosyltransferase-like 1b	0.076
igf1ra	insulin-like growth factor 1a receptor	0.073
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.072
klf4a	Kruppel-like transcription factor 4a	0.071
pwp2h	PWP2 periodic tryptophan protein homolog (yeast)	0.068
znf711	zinc finger protein 711	0.067
foxa2	forkhead box A2	0.067
sult1st4	sulfotransferase family 1, cytosolic sulfotransferase 4	0.064
igf1	insulin-like growth factor 1	0.064
si:ch1073-351m12.1	si:ch1073-351m12.1	0.062
wif1	wnt inhibitory factor 1	0.062
pax8	paired box gene 8	0.061
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.061
ptenb	phosphatase and tensin homolog B (mutated in multiple advanced cancers 1)	0.061
limk1	LIM domain kinase 1	0.060
tbx16	T-box gene 16	0.060
grem2	gremlin 2, cysteine knot superfamily	0.059
brd4	bromodomain containing 4	0.059
glra1	glycine receptor, alpha 1	0.059
boc	brother of CDO	0.057
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.056
fgfr1b	fibroblast growth factor receptor 1b	0.056
kop	askopos	0.055
lmx1b.2	LIM homeobox transcription factor 1, beta 2	0.054
fgfr1a	fibroblast growth factor receptor 1a	0.054
LOC566708	FL cytokine receptor-like	0.054
her5	hairy-related 5	0.054
tcf21	transcription factor 21	0.053
eve1	even-skipped-like1	0.053
wnt5a	wingless-type MMTV integration site family, member 5a	0.052	Zebrafish
sema3aa	semaphorin 3aa	0.052
hhip	hedgehog interacting protein	0.052
bhlhe41	basic helix-loop-helix family, member e41	0.050
sulf1	sulfatase 1	0.049
spaw	southpaw	0.049
myf6	myogenic factor 6	0.048
osr2	odd-skipped related 2 (Drosophila)	0.048
esrra	estrogen-related receptor alpha	0.046
sox3	SRY-box containing gene 3	0.046
pcdh8	protocadherin 8	0.045
bmp1a	bone morphogenetic protein 1a	0.045
mapk8b	mitogen-activated protein kinase 8b	0.044
tbx2a	T-box gene 2a	0.044
epb4.1l4	erythrocyte protein band 4.1-like 4	0.043
cx27.5	connexin 27.5	0.043
amotl2a	angiomotin like 2a	0.043
comta	catechol-O-methyltransferase a	0.042
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.042
tp73	tumor protein p73	0.041
lzts2a	leucine zipper, putative tumor suppressor 2a	0.040
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.038
col2a1a	collagen type II, alpha-1a	0.038
sox17	SRY-box containing gene 17	0.037
smad3b	MAD, mothers against decapentaplegic homolog 3b (Drosophila)	0.037
dab1b	disabled homolog 1b (Drosophila)	0.037
htra1a	HtrA serine peptidase 1a	0.037
her3	hairy-related 3	0.037
sass6	spindle assembly 6 homolog (C. elegans)	0.036
egr2b	early growth response 2b	0.036
hmx1	H6 homeo box 1	0.036
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.035
sp2	sp2 transcription factor	0.035
dlx2a	distal-less homeobox gene 2a	0.034
oxtl	oxytocin-like	0.034
gbx1	gastrulation brain homeobox 1	0.034
lft1	lefty1	0.034
smo	smoothened homolog (Drosophila)	0.034
efnb2a	ephrin B2a	0.034
foxj1a	forkhead box J1a	0.034
dag1	dystroglycan 1	0.033
vax2	ventral anterior homeobox 2	0.033
glceb	glucuronyl C5-epimerase b	0.032
gle1	GLE1 RNA export mediator homolog (yeast)	0.031
pknox1.2	pbx/knotted 1 homeobox 1.2	0.030
cfl2l	cofilin 2, like	0.030
onecutl	one cut domain, family member, like	0.030
foxn4	forkhead box N4	0.030
fgf6a	fibroblast growth factor 6a	0.030
hoxb2a	homeo box B2a	0.030
stat1b	signal transducer and activator of transcription 1b	0.029
otx2	orthodenticle homolog 2	0.029
spry2	sprouty homolog 2	0.028
ins	preproinsulin	0.028
spry4	sprouty (Drosophila) homolog 4	0.028
atp1a2a	ATPase, Na+/K+ transporting, alpha 2a polypeptide	0.028
stac3	SH3 and cysteine rich domain 3	0.028
col8a1a	collagen, type VIII, alpha 1a	0.027
lhx1b	LIM homeobox 1b	0.027
hoxc6a	homeo box C6a	0.026
edn1	endothelin 1	0.026
wnt11	wingless-type MMTV integration site family, member 11	0.026	Zebrafish
gsc	goosecoid	0.026
frzb	frizzled-related protein	0.025
barx1	BarH-like homeobox 1	0.025
nkd1	naked cuticle homolog 1 (Drosophila)	0.025
pdlim3a	PDZ and LIM domain 3a	0.025
prdm1a	PR domain containing 1a, with ZNF domain	0.025
hspb1	heat shock protein, alpha-crystallin-related, 1	0.025
hoxa11a	homeo box A11a	0.024
gpc4	glypican 4	0.024
msxb	muscle segment homeobox B	0.024
runx1	runt-related transcription factor 1	0.024
fbln1	fibulin 1	0.024
cryaa	crystallin, alpha A	0.024
hoxb1b	homeo box B1b	0.023
pax2a	paired box gene 2a	0.023
hand2	heart and neural crest derivatives expressed transcript 2	0.023
fzd10	frizzled homolog 10	0.023
has3	hyaluronan synthase 3	0.023
glcea	glucuronyl C5-epimerase a	0.023
si:dkey-236e20.2	si:dkey-236e20.2	0.023
atoh1a	atonal homolog 1a	0.023
tbx24	T-box 24	0.022
vcana	versican a	0.022
arx	aristaless related homeobox	0.022
notum3	notum 3	0.022
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.021	Zebrafish
bon	bonnie and clyde	0.021
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.020
im:7162646	im:7162646	0.020
mib	mind bomb	0.020
csnk1da	casein kinase 1, delta a	0.020
LOC100001321	hypothetical protein LOC100001321	0.020
limk2	LIM domain kinase 2	0.019
bmp7a	bone morphogenetic protein 7a	0.019
meis3	myeloid ecotropic viral integration site 3	0.019
oprm1	opioid receptor, mu 1	0.019
emx1	empty spiracles homeobox 1	0.018
lmo4a	LIM domain only 4a	0.018
ccnb1	cyclin B1	0.018
spry1	sprouty homolog 1 (Drosophila)	0.018
zgc:113210	zgc:113210	0.018
exorh	extra-ocular rhodopsin	0.018
loxl3b	lysyl oxidase-like 3b	0.018
lrmp	lymphoid-restricted membrane protein	0.018
veph	ventricular zone expressed PH domain protein	0.018
gad2	glutamate decarboxylase 2	0.018
odz4	odd Oz/ten-m homolog 4	0.018
vax1	ventral anterior homeobox 1	0.018
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.018
barx2	BarH-like homeobox 2	0.017
disc1	disrupted in schizophrenia 1	0.017
smad9	MAD homolog 9 (Drosophila)	0.017
hoxd10a	homeo box D10a	0.017
nog1	noggin 1	0.017
ndr1	nodal-related 1	0.017
ascl1b	achaete-scute complex-like 1b (Drosophila)	0.017
tnnt2a	troponin T2a, cardiac	0.017
raraa	retinoic acid receptor, alpha a	0.017
angpt1	angiopoietin 1	0.017
nkd2	naked cuticle homolog 2 and naked 2a	0.016
pglyrp2	peptidoglycan recognition protein 2	0.016
ved	ventrally expressed dharma/bozozok antagonist	0.016
sp5l	Sp5 transcription factor-like	0.016
cobl	cordon-bleu homolog (mouse)	0.016
gli3	GLI-Kruppel family member GLI3	0.016
dab1a	disabled homolog 1a (Drosophila)	0.016
robo3	roundabout homolog 3	0.016
znf503	zinc finger protein 503	0.016
per2	period homolog 2 (Drosophila)	0.016
dlx3b	distal-less homeobox gene 3b	0.016
osr1	odd-skipped related 1 (Drosophila)	0.016
hoxa3a	homeo box A3a	0.016
fgf24	fibroblast growth factor 24	0.015
cpa2	carboxypeptidase A2 (pancreatic)	0.015
ntrk1	neurotrophic tyrosine kinase, receptor, type 1	0.015
fzd5	frizzled homolog 5	0.015
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.015
cables1	Cdk5 and Abl enzyme substrate 1	0.015
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.015
etv2	ets variant gene 2	0.015
mc3r	melanocortin 3 receptor	0.014
foxp1b	forkhead box P1b	0.014
mtp	microsomal triglyceride transfer protein	0.014
cenph	centromere protein H	0.014
nog2	noggin 2	0.014
msxe	muscle segment homeobox E	0.014
sox21a	SRY-box containing gene 21a	0.014
fli1a	friend leukemia integration 1a	0.014
fgf8b	fibroblast growth factor 8 b	0.014
mmp17b	matrix metallopeptidase 17b	0.014
runx2a	runt-related transcription factor 2a	0.014
pkd2	polycystic kidney disease 2	0.014
pdlim2	PDZ and LIM domain 2 (mystique)	0.014
trim3a	tripartite motif-containing 3a	0.013
wu:fj62d01	wu:fj62d01	0.013
igfbp3	insulin-like growth factor binding protein 3	0.013
lfng	lunatic fringe homolog	0.013
pggt1b	protein geranylgeranyltransferase type I, beta subunit	0.013
ihhb	Indian hedgehog homolog b	0.013
mesp2	mesoderm posterior 2 homolog (mouse)	0.013
irx7	iroquois homeobox protein 7	0.013
fn1	fibronectin 1	0.013
avpl	arginine vasopressin-like	0.013
mecom	MDS1 and EVI1 complex locus	0.013
sim2	single-minded homolog 2 (Drosophila)	0.013
neurod4	neurogenic differentiation 4	0.013
dcc	deleted in colorectal carcinoma	0.013
fezf2	FEZ family zinc finger 2	0.013
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.013
epha4b	eph receptor A4b	0.013
zfpm1	zinc finger protein, multitype 1	0.012
hoxa9a	homeo box A9a	0.012
reln	reelin	0.012
dla	deltaA	0.012
pld1a	phospholipase D1a	0.012
hoxb5b	homeo box B5b	0.012
egr1	early growth response 1	0.012
pdlim4	PDZ and LIM domain 4	0.012
oprk1	opioid receptor, kappa 1	0.012
hoxb4a	homeo box B4a	0.012
cyp26b1	cytochrome P450, family 26, subfamily b, polypeptide 1	0.012
hoxd13a	homeo box D13a	0.012
her8a	hairy-related 8a	0.011
bactin2	bactin2	0.011
rargb	retinoic acid receptor, gamma b	0.011
ids	iduronate 2-sulfatase	0.011
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.011
igf1rb	insulin-like growth factor 1b receptor	0.011
sema3d	semaphorin 3d	0.011
cbx2	chromobox homolog 2 (Drosophila Pc class)	0.011
vox	ventral homeobox	0.011
rxrbb	retinoid x receptor, beta b	0.011
cx44.1	connexin 44.1	0.011
hoxd11a	homeo box D11a	0.011
oprd1a	opioid receptor, delta 1a	0.010
gdnf	glial cell derived neurotrophic factor	0.010
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.010
sox32	SRY-box containing gene 32	0.010
anxa4	annexin A4	0.010
rxrab	retinoid x receptor, alpha b	0.010
itgav	integrin, alpha V	0.010
mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.010
efnb3b	ephrin B3b	0.010