IMP
Process View
The network for 'positive regulation of cytokine mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of cytokine mediated signaling pathway
Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| GRB2 | growth factor receptor-bound protein 2 | 0.998 | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.986 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.971 | |
| LCK | lymphocyte-specific protein tyrosine kinase | 0.950 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.947 | |
| SYK | spleen tyrosine kinase | 0.889 | |
| HCK | hemopoietic cell kinase | 0.581 | |
| EGFR | epidermal growth factor receptor | 0.529 | |
| TBK1 | TANK-binding kinase 1 | 0.446 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.400 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.369 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.351 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.333 | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.296 | |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.280 | |
| GAS6 | growth arrest-specific 6 | 0.263 | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.262 | |
| AXL | AXL receptor tyrosine kinase | 0.255 | |
| PLCG1 | phospholipase C, gamma 1 | 0.251 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.197 | |
| TLR4 | toll-like receptor 4 | 0.186 | |
| NCK1 | NCK adaptor protein 1 | 0.180 | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.179 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.173 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.167 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.139 | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.127 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.113 | |
| ZNF746 | zinc finger protein 746 | 0.096 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.090 | |
| SPRR2A | small proline-rich protein 2A | 0.087 | |
| LAT | linker for activation of T cells | 0.085 | |
| FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.078 | |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.072 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.071 | |
| BLNK | B-cell linker | 0.070 | |
| ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.068 | |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.067 | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.062 | |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.060 | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.057 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.056 | |
| TRAF3 | TNF receptor-associated factor 3 | 0.055 | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.054 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.053 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.047 | |
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.047 | |
| ITK | IL2-inducible T-cell kinase | 0.046 | |
| GAB1 | GRB2-associated binding protein 1 | 0.046 | |
| IL1R1 | interleukin 1 receptor, type I | 0.045 | |
| TMEM173 | transmembrane protein 173 | 0.039 | |
| IL1RAP | interleukin 1 receptor accessory protein | 0.037 | |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.034 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.033 | |
| NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.033 | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.032 | |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.032 | |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.030 | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.030 | |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.028 | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.025 | |
| GAS7 | growth arrest-specific 7 | 0.024 | |
| KLHL24 | kelch-like 24 (Drosophila) | 0.024 | |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.023 | |
| MUC1 | mucin 1, cell surface associated | 0.022 | |
| VAV2 | vav 2 guanine nucleotide exchange factor | 0.020 | |
| IRF3 | interferon regulatory factor 3 | 0.020 | |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.019 | |
| TENC1 | tensin like C1 domain containing phosphatase (tensin 2) | 0.019 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.019 | |
| CD2AP | CD2-associated protein | 0.019 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.018 | |
| NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.018 | |
| IRS1 | insulin receptor substrate 1 | 0.018 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.018 | |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.017 | |
| WIPF1 | WAS/WASL interacting protein family, member 1 | 0.017 | |
| PLXNB1 | plexin B1 | 0.017 | |
| MED28 | mediator complex subunit 28 | 0.015 | |
| SH2B2 | SH2B adaptor protein 2 | 0.015 | |
| NELL2 | NEL-like 2 (chicken) | 0.014 | |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.014 | |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.014 | |
| FES | feline sarcoma oncogene | 0.013 | |
| MAVS | mitochondrial antiviral signaling protein | 0.013 | |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.012 | |
| TRAF6 | TNF receptor-associated factor 6 | 0.012 | |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.012 | |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.012 | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.012 | |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.011 | |
| PELI3 | pellino homolog 3 (Drosophila) | 0.011 | |
| JAG2 | jagged 2 | 0.010 | |
| TNS4 | tensin 4 | 0.010 |
