The network for 'generation of neurons' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

generation of neurons

The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.

Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
EGFR epidermal growth factor receptor 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.998
TP53 tumor protein p53 0.998
FYN FYN oncogene related to SRC, FGR, YES 0.998
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.998
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.997
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.995
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.993
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.988
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.987
FLNA filamin A, alpha 0.982
CREBBP CREB binding protein 0.979
GRB2 growth factor receptor-bound protein 2 0.979
QKI quaking homolog, KH domain RNA binding (mouse) 0.978
MAPT microtubule-associated protein tau 0.977
JUN jun proto-oncogene 0.969
NCOA1 nuclear receptor coactivator 1 0.957
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.942
RB1 retinoblastoma 1 0.930
AR androgen receptor 0.928
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.924
FN1 fibronectin 1 0.915
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.911
HDAC1 histone deacetylase 1 0.909
SMAD2 SMAD family member 2 0.901
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.880
GSK3B glycogen synthase kinase 3 beta 0.857
ATXN1 ataxin 1 0.855
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.851
SP1 Sp1 transcription factor 0.840
NCOR1 nuclear receptor corepressor 1 0.824
DLG4 discs, large homolog 4 (Drosophila) 0.813
SPTBN1 spectrin, beta, non-erythrocytic 1 0.810
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.795
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.794
ACTB actin, beta 0.783
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.776
EP300 E1A binding protein p300 0.770
TAL1 T-cell acute lymphocytic leukemia 1 0.767
SMN1 survival of motor neuron 1, telomeric 0.752
PLCG1 phospholipase C, gamma 1 0.751
LCK lymphocyte-specific protein tyrosine kinase 0.746
FGFR1 fibroblast growth factor receptor 1 0.739
BMI1 BMI1 polycomb ring finger oncogene 0.733
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.721
SMAD4 SMAD family member 4 0.716
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.712
PCGF2 polycomb group ring finger 2 0.709
FHL2 four and a half LIM domains 2 0.699
IQGAP1 IQ motif containing GTPase activating protein 1 0.689
ITSN1 intersectin 1 (SH3 domain protein) 0.686
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.685
ATN1 atrophin 1 0.682
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.676
APC adenomatous polyposis coli 0.673
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 0.672
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.665
MET met proto-oncogene (hepatocyte growth factor receptor) 0.663
PRKCA protein kinase C, alpha 0.660
MAP2K1 mitogen-activated protein kinase kinase 1 0.656
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.656
BCAR1 breast cancer anti-estrogen resistance 1 0.655
TCF4 transcription factor 4 0.650
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.650
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.647
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.646
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.645
HSPA1B heat shock 70kDa protein 1B 0.642
EED embryonic ectoderm development 0.641
CDK2 cyclin-dependent kinase 2 0.639
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.637
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.637
MEOX2 mesenchyme homeobox 2 0.634
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.630
MYOD1 myogenic differentiation 1 0.624
IGF1R insulin-like growth factor 1 receptor 0.623
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.615
RUNX1 runt-related transcription factor 1 0.613
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.612
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.596
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.595
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.591
MAPK8 mitogen-activated protein kinase 8 0.582
STK4 serine/threonine kinase 4 0.579
WDYHV1 WDYHV motif containing 1 0.579
USP11 ubiquitin specific peptidase 11 0.578
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.574
DRD2 dopamine receptor D2 0.573
RANBP9 RAN binding protein 9 0.572
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.572
JAG2 jagged 2 0.567
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.567
MARK2 MAP/microtubule affinity-regulating kinase 2 0.556
TP73 tumor protein p73 0.554
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.998
unc-9 Protein UNC-9 0.934
vab-3 Protein VAB-3 0.919
pha-4 Protein PHA-4 0.911
unc-52 Protein UNC-52 0.904
nhr-67 Protein NHR-67 0.880
ceh-20 Protein CEH-20 0.857
pry-1 Protein PRY-1 0.833
sax-3 Protein SAX-3 0.806
sem-5 Protein SEM-5 0.743
bar-1 Protein BAR-1 0.724
daf-11 Protein DAF-11 0.711
cfim-2 Protein CFIM-2 0.708
unc-73 Protein UNC-73 0.667
let-60 Protein LET-60 0.650
ain-1 Protein AIN-1 0.635
cye-1 Protein CYE-1 0.635
aap-1 Protein AAP-1 0.634
syg-1 Protein SYG-1 0.632
unc-42 Protein UNC-42 0.632
npp-4 Protein NPP-4 0.631
egl-46 Protein EGL-46 0.628
T27A3.1 Protein T27A3.1 0.626
spc-1 Protein SPC-1 0.625
ten-1 Protein TEN-1 0.615
mig-2 Protein MIG-2 0.595
egl-44 Protein EGL-44 0.571
sli-1 Protein SLI-1 0.570
osm-3 Protein OSM-3 0.568
ect-2 Protein ECT-2 0.561
tax-4 Protein TAX-4 0.560
goa-1 Protein GOA-1 0.549
sur-6 Protein SUR-6 0.503
egl-15 Protein EGL-15 0.501
nhr-34 Protein NHR-34 0.497
vab-10 Protein VAB-10 0.486
pxf-1 Protein PXF-1 0.477
hbl-1 Protein HBL-1 0.475
inx-3 Protein INX-3 0.473
unc-62 Protein UNC-62 0.473
smp-1 Protein SMP-1 0.470
egl-36 Protein EGL-36 0.461
eor-1 Protein EOR-1 0.459
C11E4.6 Protein C11E4.6 0.448
hlh-1 Protein HLH-1 0.444
sorb-1 Protein SORB-1 0.436
F33H2.3 Protein F33H2.3 0.432
unc-104 Protein UNC-104 0.430
hlh-2 Protein HLH-2 0.423
pkg-1 Protein PKG-1 0.417
egl-5 Protein EGL-5 0.409
adr-1 Protein ADR-1 0.407
clk-2 Protein CLK-2 0.405
scc-3 Protein SCC-3 0.400
osm-6 Protein OSM-6 0.399
sma-6 Protein SMA-6 0.398
clh-5 Protein CLH-5 0.398
ifg-1 Protein IFG-1 0.395
fln-2 Protein FLN-2 0.390
egl-27 Protein EGL-27 0.385
pdfr-1 Protein PDFR-1 0.377
daf-12 Protein DAF-12 0.372
tbc-3 Protein TBC-3 0.368
flt-1 Protein FLT-1 0.367
K10D6.4 Protein K10D6.4 0.367
wrm-1 Protein WRM-1 0.362
pat-3 Protein PAT-3 0.362
sdz-28 Protein SDZ-28 0.362
set-1 Protein SET-1 0.359
lat-1 Protein LAT-1 0.355
cam-1 Protein CAM-1 0.354
elt-6 Protein ELT-6 0.352
unc-70 Protein UNC-70 0.347
ldb-1 Protein LDB-1 0.344
T23F11.1 Protein T23F11.1 0.343
CELE_F54D5.5 Protein F54D5.5 0.339
tag-260 Protein TAG-260 0.338
lin-29 Protein LIN-29 0.335
sel-12 Protein SEL-12 0.335
mec-4 Protein MEC-4 0.331
enu-3 Protein ENU-3 0.319
eya-1 Protein EYA-1 0.316
fcp-1 Protein FCP-1 0.316
egl-13 Protein EGL-13 0.316
unc-27 Protein UNC-27 0.314
T28F4.1 Protein T28F4.1 0.313
lin-12 Protein LIN-12 0.312
hda-3 Protein HDA-3 0.312
srgp-1 Protein SRGP-1 0.306
lam-2 Protein LAM-2 0.305
F09A5.4 Protein F09A5.4 0.301
ceh-27 Protein CEH-27 0.299
zyg-9 Protein ZYG-9 0.299
apb-1 Protein APB-1 0.297
pop-1 Protein POP-1 0.295
ida-1 Protein IDA-1 0.294
mec-6 Protein MEC-6 0.293
glp-1 Protein GLP-1 0.293
T07A9.10 Protein T07A9.10 0.291
unc-115 Protein UNC-115 0.285
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Danio rerio
Name Description Probability Func Analog Organism
pax2a paired box gene 2a 0.999
gdf6a growth differentiation factor 6a 0.999
gli1 GLI-Kruppel family member 1 0.997
ndr2 nodal-related 2 0.997
otx2 orthodenticle homolog 2 0.996
lhx2b LIM homeobox 2b 0.995
per3 period homolog 3 (Drosophila) 0.995
gli2a GLI-Kruppel family member GLI2a 0.994
notch1a notch homolog 1a 0.992
ascl1a achaete-scute complex-like 1a (Drosophila) 0.992
neurod neurogenic differentiation 0.991
isl1 islet1 0.991
shha sonic hedgehog a 0.991
eng2a engrailed 2a 0.989
pitx3 paired-like homeodomain transcription factor 3 0.987
otpa orthopedia homolog a 0.986
ptf1a pancreas specific transcription factor, 1a 0.986
nsfa N-ethylmaleimide-sensitive factor a 0.985
fezf2 FEZ family zinc finger 2 0.985
atoh1a atonal homolog 1a 0.980
rest RE1-silencing transcription factor 0.979
rx3 retinal homeobox gene 3 0.977
robo2 roundabout homolog 2 0.976
hhip hedgehog interacting protein 0.975
lamc1 laminin, gamma 1 0.971
crb2a crumbs homolog 2a 0.971
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.970
six3a sine oculis homeobox homolog 3a 0.968
shhb sonic hedgehog b 0.966
nes nestin 0.964
pitx2 paired-like homeodomain transcription factor 2 0.964
otx5 orthodenticle homolog 5 0.962
pax6b paired box gene 6b 0.962
flh floating head 0.961
six3b sine oculis homeobox homolog 3b 0.957
hmx3 homeo box (H6 family) 3 0.956
otpb orthopedia homolog b 0.956
coe2 coe2 0.956
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.955
jag1b jagged 1b 0.955
foxp2 forkhead box P2 0.955
ndrg4 N-myc downstream regulated gene 4 0.955
osr1 odd-skipped related 1 (Drosophila) 0.955
ptch2 patched 2 0.952
sox2 SRY-box containing gene 2 0.951
sema3aa semaphorin 3aa 0.951
atoh7 atonal homolog 7 0.947
musk muscle, skeletal, receptor tyrosine kinase 0.947
rx2 retinal homeobox gene 2 0.946
prkci protein kinase C, iota 0.946
foxn4 forkhead box N4 0.942
s1pr2 sphingosine-1-phosphate receptor 2 0.941
dlc deltaC 0.941
wnt4a wingless-type MMTV integration site family, member 4a 0.940
gbx2 gastrulation brain homeo box 2 0.940
tp53 tumor protein p53 0.939
jag2 jagged 2 0.938
rarga retinoic acid receptor gamma a 0.938
myod1 myogenic differentiation 1 0.937
rad21 RAD21 homolog (S. pombe) 0.934
olig2 oligodendrocyte lineage transcription factor 2 0.933
chat choline acetyltransferase 0.932
dharma dharma 0.932
fn1 fibronectin 1 0.932
nrp2b neuropilin 2b 0.931
nkx2.2a NK2 transcription factor related 2a 0.930
cntn2 contactin 2 0.927
dld deltaD 0.925
fgf3 fibroblast growth factor 3 0.923
tuba1 tubulin, alpha 1 0.923
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.922
irx4b iroquois homeobox protein 4b 0.921
stmn2b stathmin-like 2b 0.921
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.921
slc1a2b solute carrier family 1 (glial high affinity glutamate transporter), member 2b 0.919
dlx5a distal-less homeobox gene 5a 0.918
dpysl3 dihydropyrimidinase-like 3 0.917
th tyrosine hydroxylase 0.916
foxi1 forkhead box I1 0.915
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.914
otx1a orthodenticle homolog 1a 0.914
nrp1a neuropilin 1a 0.914
cdh2 cadherin 2, neuronal 0.913
egr2b early growth response 2b 0.911
dlx4b distal-less homeobox gene 4b 0.910
foxg1a forkhead box G1a 0.909
kbp kif1-binding protein 0.909
her15.1 hairy and enhancer of split-related 15.1 0.906
dlx2a distal-less homeobox gene 2a 0.903
fstl1b follistatin-like 1b 0.902
igf1ra insulin-like growth factor 1a receptor 0.900
ift88 intraflagellar transport 88 homolog 0.898
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.895
hnf1ba HNF1 homeobox Ba 0.890
wnt11 wingless-type MMTV integration site family, member 11 0.890
alcamb activated leukocyte cell adhesion molecule b 0.889
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.889
wnt5b wingless-type MMTV integration site family, member 5b 0.889
lhx1a LIM homeobox 1a 0.889
mtp microsomal triglyceride transfer protein 0.885
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism