The network for 'antimicrobial peptide production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

antimicrobial peptide production

The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.

Mus musculus
Name Description Probability Func Analog Organism
Tlr4 toll-like receptor 4 1.000
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 1.000
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 1.000
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.999
Tnf tumor necrosis factor 0.999
Ikbkg inhibitor of kappaB kinase gamma 0.997
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.995
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.987
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.967
Ikbkb inhibitor of kappaB kinase beta 0.942
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.937
Gata4 GATA binding protein 4 0.829
Rxra retinoid X receptor alpha 0.797
Pycard PYD and CARD domain containing 0.790
Socs1 suppressor of cytokine signaling 1 0.723
Per1 period homolog 1 (Drosophila) 0.699
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.649
Bcl3 B-cell leukemia/lymphoma 3 0.649
Nlrp3 NLR family, pyrin domain containing 3 0.631
Tlr2 toll-like receptor 2 0.550
Neurog2 neurogenin 2 0.548
Gata6 GATA binding protein 6 0.489
Cd40 CD40 antigen 0.470
Tnip1 TNFAIP3 interacting protein 1 0.469
Irf1 interferon regulatory factor 1 0.462
Il1b interleukin 1 beta 0.461
Cd44 CD44 antigen 0.421
Icam1 intercellular adhesion molecule 1 0.380
Gbp5 guanylate binding protein 5 0.324
Pax2 paired box gene 2 0.289
Chuk conserved helix-loop-helix ubiquitous kinase 0.283
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.278
Gata5 GATA binding protein 5 0.267
Cdx2 caudal type homeobox 2 0.261
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.260
Lyz2 lysozyme 2 0.247
Wnt7b wingless-related MMTV integration site 7B 0.239
Ticam1 toll-like receptor adaptor molecule 1 0.225
Igh immunoglobulin heavy chain complex 0.211
Trp53 transformation related protein 53 0.208
Vps72 vacuolar protein sorting 72 (yeast) 0.195
Cyld cylindromatosis (turban tumor syndrome) 0.191
Casp1 caspase 1 0.187
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.181
Clec4d C-type lectin domain family 4, member d 0.180
2010106G01Rik RIKEN cDNA 2010106G01 gene 0.180
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.179
Aim2 absent in melanoma 2 0.177
Il1rn interleukin 1 receptor antagonist 0.172
Ltbp2 latent transforming growth factor beta binding protein 2 0.172
Cxcl2 chemokine (C-X-C motif) ligand 2 0.167
Il18 interleukin 18 0.163
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.161
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.156
Ccr1 chemokine (C-C motif) receptor 1 0.156
Foxp3 forkhead box P3 0.149
Gbp2 guanylate binding protein 2 0.140
Tesk1 testis specific protein kinase 1 0.140
Shf Src homology 2 domain containing F 0.137
Birc3 baculoviral IAP repeat-containing 3 0.136
ORF61 open reading frame 61 0.132
Trim28 tripartite motif-containing 28 0.131
Pik3r2 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta) 0.131
Ephb2 Eph receptor B2 0.127
Myd88 myeloid differentiation primary response gene 88 0.126
Traf6 TNF receptor-associated factor 6 0.124
Mefv Mediterranean fever 0.118
Il7 interleukin 7 0.117
H1fx H1 histone family, member X 0.115
Clec4e C-type lectin domain family 4, member e 0.113
C1qtnf1 C1q and tumor necrosis factor related protein 1 0.111
Rnf31 ring finger protein 31 0.110
Mta1 metastasis associated 1 0.109
Cxcl13 chemokine (C-X-C motif) ligand 13 0.107
Zfp574 zinc finger protein 574 0.105
Alx4 aristaless-like homeobox 4 0.104
Plau plasminogen activator, urokinase 0.104
Ooep oocyte expressed protein homolog (dog) 0.102
Irg1 immunoresponsive gene 1 0.101
Nkain1 Na+/K+ transporting ATPase interacting 1 0.100
Tle6 transducin-like enhancer of split 6, homolog of Drosophila E(spl) 0.100
Dlx1 distal-less homeobox 1 0.099
E2f1 E2F transcription factor 1 0.099
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.096
Wnt6 wingless-related MMTV integration site 6 0.096
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.095
Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) 0.091
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.090
Ccl7 chemokine (C-C motif) ligand 7 0.084
Il6 interleukin 6 0.083
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.083
Btbd2 BTB (POZ) domain containing 2 0.082
Gata1 GATA binding protein 1 0.081
Cnih2 cornichon homolog 2 (Drosophila) 0.079
Git1 G protein-coupled receptor kinase-interactor 1 0.079
Ikzf1 IKAROS family zinc finger 1 0.078
Prap1 proline-rich acidic protein 1 0.078
Tcf3 transcription factor 3 0.077
Chpf chondroitin polymerizing factor 0.077
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 1.000
PGRP-LC Peptidoglycan recognition protein LC 0.999
AttA Attacin-A 0.986
SPE Spatzle-Processing Enzyme 0.951
Spn27A Serpin 27A 0.946
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.942
Tl Toll 0.933
ird5 immune response deficient 5 0.923
Sp7 Serine protease 7 0.920
DptB Diptericin B 0.909
Spn28D Serpin 28D 0.827
fon fondue 0.817
ird1 immune response deficient 1 0.791
PGRP-SA Peptidoglycan recognition protein SA 0.767
grass Gram-positive Specific Serine protease 0.759
key kenny 0.698
cact cactus 0.647
Mtk Metchnikowin 0.643
BG4 CG12297 gene product from transcript CG12297-RA 0.636
Dredd Death related ced-3/Nedd2-like protein 0.619
spz spatzle 0.615
imd immune deficiency 0.607
ac achaete 0.513
Myd88 CG2078 gene product from transcript CG2078-RA 0.508
Mpk2 CG5475 gene product from transcript CG5475-RB 0.430
Irc Immune-regulated catalase 0.425
AttC Attacin-C 0.401
AGO2 Argonaute 2 0.395
Spn1 Serine protease inhibitor 1 0.379
CG32185 CG32185 gene product from transcript CG32185-RA 0.288
Glt Glutactin 0.288
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.228
Pvr PDGF- and VEGF-receptor related 0.212
ush u-shaped 0.208
pirk poor Imd response upon knock-in 0.199
sc scute 0.197
CG15917 CG15917 gene product from transcript CG15917-RA 0.193
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.147
th thread 0.142
GNBP3 Gram-negative bacteria binding protein 3 0.135
Dpt Diptericin 0.126
IM18 Immune induced molecule 18 0.122
tsl torso-like 0.122
CG15065 CG15065 gene product from transcript CG15065-RA 0.119
bowl brother of odd with entrails limited 0.116
Tak1 TGF-beta activated kinase 1 0.111
modSP modular serine protease 0.110
Notum CG13076 gene product from transcript CG13076-RB 0.109
Spn88Eb Serpin 88Eb 0.100
psh persephone 0.097
CG7910 CG7910 gene product from transcript CG7910-RA 0.095
CecC Cecropin C 0.094
gpp grappa 0.093
egr eiger 0.093
HLHmgamma E(spl) region transcript mgamma 0.091
nmo nemo 0.091
CG18594 CG18594 gene product from transcript CG18594-RA 0.090
aop anterior open 0.089
bcd bicoid 0.088
CG11286 CG11286 gene product from transcript CG11286-RA 0.083
amos absent MD neurons and olfactory sensilla 0.082
Drs Drosomycin 0.082
CG8586 CG8586 gene product from transcript CG8586-RA 0.080
su(Hw) suppressor of Hairy wing 0.079
nub nubbin 0.077
Duox Dual oxidase 0.076
Nc Nedd2-like caspase 0.075
corto CG2530 gene product from transcript CG2530-RA 0.073
Tsp42Ef Tetraspanin 42Ef 0.072
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.072
p38b CG7393 gene product from transcript CG7393-RA 0.072
Traf6 TNF-receptor-associated factor 6 0.070
spirit Serine Protease Immune Response Integrator 0.070
eater CG6124 gene product from transcript CG6124-RB 0.069
l(3)mbn lethal (3) malignant blood neoplasm 0.069
Mekk1 CG7717 gene product from transcript CG7717-RB 0.065
CG12766 CG12766 gene product from transcript CG12766-RA 0.065
CG13641 CG13641 gene product from transcript CG13641-RA 0.062
PGRP-LB Peptidoglycan recognition protein LB 0.062
Gadd45 CG11086 gene product from transcript CG11086-RA 0.059
Rfx CG6312 gene product from transcript CG6312-RA 0.059
Fhos CG42610 gene product from transcript CG42610-RC 0.059
CG42300 CG42300 gene product from transcript CG42300-RA 0.059
Adgf-A Adenosine deaminase-related growth factor A 0.059
CecA2 Cecropin A2 0.057
Tab2 TAK1-associated binding protein 2 0.056
CG16772 CG16772 gene product from transcript CG16772-RA 0.056
cpb capping protein beta 0.056
eg eagle 0.054
PGRP-LF Peptidoglycan recognition protein LF 0.053
Cad96Ca CG10244 gene product from transcript CG10244-RA 0.052
sca scabrous 0.051
l(3)05822 lethal (3) 05822 0.050
GNBP1 Gram-negative bacteria binding protein 1 0.049
Vps16A Vacuolar protein sorting 16A 0.049
Gef64C Guanine nucleotide exchange factor GEF64C 0.049
Ark Apaf-1-related-killer 0.047
Jupiter CG31363 gene product from transcript CG31363-RD 0.047
TepIII Thiolester containing protein III 0.047
Toll-7 CG8595 gene product from transcript CG8595-RA 0.047
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism