Process View
The network for 'protein kinase b signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Grb2 | growth factor receptor bound protein 2 | 0.990 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.979 | |
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.932 | |
Egfr | epidermal growth factor receptor | 0.920 | |
Insr | insulin receptor | 0.917 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.886 | |
Cbl | Casitas B-lineage lymphoma | 0.876 | |
Ghr | growth hormone receptor | 0.825 | |
Eda | ectodysplasin-A | 0.823 | |
Apoe | apolipoprotein E | 0.807 | |
Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.791 | |
Apc | adenomatosis polyposis coli | 0.759 | |
Rb1 | retinoblastoma 1 | 0.756 | |
Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.754 | |
Pten | phosphatase and tensin homolog | 0.742 | |
Tnf | tumor necrosis factor | 0.698 | |
Cd40 | CD40 antigen | 0.697 | |
Bdnf | brain derived neurotrophic factor | 0.687 | |
Axl | AXL receptor tyrosine kinase | 0.670 | |
Nos1 | nitric oxide synthase 1, neuronal | 0.669 | |
Fgf3 | fibroblast growth factor 3 | 0.662 | |
Slc34a1 | solute carrier family 34 (sodium phosphate), member 1 | 0.657 | |
Sox2 | SRY-box containing gene 2 | 0.646 | |
Nf1 | neurofibromatosis 1 | 0.634 | |
Ret | ret proto-oncogene | 0.630 | |
Adam12 | a disintegrin and metallopeptidase domain 12 (meltrin alpha) | 0.625 | |
Nr3c1 | nuclear receptor subfamily 3, group C, member 1 | 0.624 | |
Lta | lymphotoxin A | 0.617 | |
Cd44 | CD44 antigen | 0.592 | |
Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.582 | |
Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.574 | |
Esr1 | estrogen receptor 1 (alpha) | 0.551 | |
Ccr1 | chemokine (C-C motif) receptor 1 | 0.536 | |
Ntf3 | neurotrophin 3 | 0.531 | |
Grb10 | growth factor receptor bound protein 10 | 0.529 | |
Mup10 | major urinary protein 10 | 0.519 | |
Htra3 | HtrA serine peptidase 3 | 0.494 | |
Lmna | lamin A | 0.493 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.490 | |
Shh | sonic hedgehog | 0.489 | |
Cav1 | caveolin 1, caveolae protein | 0.465 | |
Pbx1 | pre B-cell leukemia transcription factor 1 | 0.465 | |
Nos2 | nitric oxide synthase 2, inducible | 0.462 | |
Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.450 | |
Ccl4 | chemokine (C-C motif) ligand 4 | 0.449 | |
Ifng | interferon gamma | 0.444 | |
Atoh7 | atonal homolog 7 (Drosophila) | 0.437 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.437 | |
Lepr | leptin receptor | 0.427 | |
Phox2a | paired-like homeobox 2a | 0.421 | |
Ntrk3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.404 | |
Spry4 | sprouty homolog 4 (Drosophila) | 0.404 | |
Tnfsf11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.384 | |
Parva | parvin, alpha | 0.383 | |
Fzd1 | frizzled homolog 1 (Drosophila) | 0.383 | |
Socs1 | suppressor of cytokine signaling 1 | 0.381 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.377 | |
Meox2 | mesenchyme homeobox 2 | 0.375 | |
Ednra | endothelin receptor type A | 0.375 | |
Tyro3 | TYRO3 protein tyrosine kinase 3 | 0.375 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.372 | |
Rbl2 | retinoblastoma-like 2 | 0.367 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.341 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.340 | |
Oc90 | otoconin 90 | 0.338 | |
Nog | noggin | 0.337 | |
Arrb1 | arrestin, beta 1 | 0.337 | |
Arrb2 | arrestin, beta 2 | 0.335 | |
C3ar1 | complement component 3a receptor 1 | 0.330 | |
Adam17 | a disintegrin and metallopeptidase domain 17 | 0.325 | |
LOC100048884 | novel member of the major urinary protein (Mup) gene family | 0.324 | |
Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.323 | |
Sox4 | SRY-box containing gene 4 | 0.322 | |
Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.319 | |
Icos | inducible T-cell co-stimulator | 0.316 | |
Plcg1 | phospholipase C, gamma 1 | 0.304 | |
Wnt5a | wingless-related MMTV integration site 5A | 0.302 | |
Btk | Bruton agammaglobulinemia tyrosine kinase | 0.301 | |
Grin2b | glutamate receptor, ionotropic, NMDA2B (epsilon 2) | 0.297 | |
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.296 | |
Grin2a | glutamate receptor, ionotropic, NMDA2A (epsilon 1) | 0.291 | |
Tenc1 | tensin like C1 domain-containing phosphatase | 0.288 | |
Utf1 | undifferentiated embryonic cell transcription factor 1 | 0.283 | |
Il10 | interleukin 10 | 0.272 | |
Crhr1 | corticotropin releasing hormone receptor 1 | 0.270 | |
Pax3 | paired box gene 3 | 0.267 | |
Timp3 | tissue inhibitor of metalloproteinase 3 | 0.266 | |
Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.262 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.258 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.256 | |
Pou3f3 | POU domain, class 3, transcription factor 3 | 0.255 | |
Bmp4 | bone morphogenetic protein 4 | 0.254 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.254 | |
Prop1 | paired like homeodomain factor 1 | 0.254 | |
Htr1d | 5-hydroxytryptamine (serotonin) receptor 1D | 0.247 | |
Mgat3 | mannoside acetylglucosaminyltransferase 3 | 0.246 | |
Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.244 | |
Prlr | prolactin receptor | 0.244 | |
C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.242 | |
Braf | Braf transforming gene | 0.240 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
tp53bp2 | tumor protein p53 binding protein, 2 | 0.581 | |
igf1rb | insulin-like growth factor 1b receptor | 0.531 | |
stc1l | stanniocalcin 1, like | 0.206 | |
ptk2.1 | protein tyrosine kinase 2a | 0.190 | |
jag1b | jagged 1b | 0.139 | |
mmp9 | matrix metalloproteinase 9 | 0.128 | |
igf1 | insulin-like growth factor 1 | 0.104 | |
vdra | vitamin D receptor a | 0.091 | |
rag1 | recombination activating gene 1 | 0.089 | |
hif1ab | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b | 0.088 | |
zbtb4 | zinc finger and BTB domain containing 4 | 0.088 | |
tp73 | tumor protein p73 | 0.082 | |
pomt2 | protein-O-mannosyltransferase 2 | 0.079 | |
il1b | interleukin 1, beta and interleukin 1, beta | 0.072 | |
ncf1 | neutrophil cytosolic factor 1 | 0.072 | |
nphs1l | nephrosis 1, congenital, Finnish type (nephrin)-like | 0.067 | |
drd2a | dopamine receptor D2a | 0.066 | |
fn1 | fibronectin 1 | 0.062 | |
srf | serum response factor | 0.062 | |
si:ch73-9j13.1 | si:ch73-9j13.1 | 0.058 | |
gadd45ba | growth arrest and DNA-damage-inducible, beta a | 0.058 | |
runx2b | runt-related transcription factor 2b | 0.054 | |
btg2 | B-cell translocation gene 2 | 0.053 | |
igfbp2b | insulin-like growth factor binding protein 2b | 0.052 | |
furinb | furin (paired basic amino acid cleaving enzyme) b | 0.051 | |
pomt1 | protein-O-mannosyltransferase 1 | 0.051 | |
ifnphi1 | interferon phi 1 | 0.050 | |
LOC567965 | rho GTPase-activating protein 7-like | 0.048 | |
slc4a2a | solute carrier family 4, anion exchanger, member 2a | 0.047 | |
arhgef7b | Rho guanine nucleotide exchange factor (GEF) 7b | 0.046 | |
fgf8a | fibroblast growth factor 8 a | 0.044 | |
itga5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.042 | |
ghra | growth hormone receptor a | 0.039 | |
ocrl | oculocerebrorenal syndrome of Lowe | 0.038 | |
evx1 | even-skipped homeobox 1 | 0.037 | |
fxr2 | fragile X mental retardation, autosomal homolog 2 | 0.037 | |
zgc:112986 | zgc:112986 | 0.036 | |
trpv6 | transient receptor potential cation channel, subfamily V, member 6 | 0.034 | |
nrg2a | neuregulin 2a | 0.034 | |
emp2 | epithelial membrane protein 2 | 0.034 | |
zgc:85866 | zgc:85866 | 0.033 | |
ca10a | carbonic anhydrase Xa | 0.032 | |
fabp11a | fatty acid binding protein 11a | 0.031 | |
scn1a | sodium channel, voltage-gated, type I, alpha | 0.031 | |
vegfaa | vascular endothelial growth factor Aa | 0.031 | |
igf2a | insulin-like growth factor 2a | 0.030 | |
insra | insulin receptor a | 0.030 | |
ctgf | connective tissue growth factor | 0.029 | |
arntl1a | aryl hydrocarbon receptor nuclear translocator-like 1a | 0.029 | |
LOC100534970 | hypothetical protein LOC100534970 | 0.028 | |
pxn | paxillin | 0.028 | |
flt4 | fms-related tyrosine kinase 4 | 0.027 | |
dag1 | dystroglycan 1 | 0.026 | |
si:ch211-195h23.3 | si:ch211-195h23.3 | 0.026 | |
ahctf1 | AT hook containing transcription factor 1 | 0.026 | |
igf2b | insulin-like growth factor 2b | 0.025 | |
zgc:101724 | zgc:101724 | 0.025 | |
colec11 | collectin sub-family member 11 | 0.025 | |
eng2a | engrailed 2a | 0.024 | |
tpm3 | tropomyosin 3 | 0.024 | |
igf1ra | insulin-like growth factor 1a receptor | 0.024 | |
pdgfaa | platelet-derived growth factor alpha a | 0.024 | |
kal1a | Kallmann syndrome 1a sequence | 0.024 | |
psen1 | presenilin 1 | 0.024 | |
flt1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.024 | |
nr1h5 | nuclear receptor subfamily 1, group H, member 5 | 0.024 | |
cyp26b1 | cytochrome P450, family 26, subfamily b, polypeptide 1 | 0.023 | |
rc3 | rabconnectin 3 | 0.023 | |
wt1b | wilms tumor 1b | 0.023 | |
tnfa | tumor necrosis factor a (TNF superfamily, member 2) | 0.023 | |
pax7a | paired box gene 7a | 0.023 | |
il8 | interleukin 8 | 0.022 | |
nadl1.2 | neural adhesion molecule L1.2 | 0.022 | |
fgf4 | fibroblast growth factor 4 | 0.022 | |
crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.022 | |
zgc:112257 | zgc:112257 | 0.021 | |
jup | junction plakoglobin | 0.021 | |
zgc:112072 | zgc:112072 | 0.021 | |
sulf1 | sulfatase 1 | 0.021 | |
ntrk3b | neurotrophic tyrosine kinase, receptor, type 3b | 0.021 | |
ptgs1 | prostaglandin-endoperoxide synthase 1 | 0.021 | |
ptprf | protein tyrosine phosphatase, receptor type, F | 0.020 | |
gadd45bb | growth arrest and DNA-damage-inducible, beta b | 0.020 | |
tlr3 | toll-like receptor 3 | 0.020 | |
mbtps1 | membrane-bound transcription factor protease, site 1 | 0.020 | |
fbln4 | fibulin 4 | 0.020 | |
ncam2 | neural cell adhesion molecule 2 | 0.020 | |
kif5bb | kinesin family member 5B, b | 0.020 | |
mapk1 | mitogen-activated protein kinase 1 | 0.019 | |
ppip5k1 | diphosphoinositol pentakisphosphate kinase 1 | 0.019 | |
insrb | insulin receptor b | 0.019 | |
ripk2 | receptor-interacting serine-threonine kinase 2 | 0.019 | |
foxc1a | forkhead box C1a | 0.019 | |
zgc:86759 | zgc:86759 | 0.018 | |
odc1 | ornithine decarboxylase 1 | 0.018 | |
LOC565839 | tumor necrosis factor alpha-induced protein 2-like | 0.018 | |
stmn2b | stathmin-like 2b | 0.018 | |
skia | nuclear oncoprotein skia | 0.018 | |
hlxb9la | homeo box HB9 like a | 0.018 | |
trim55a | tripartite motif-containing 55a | 0.017 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.298 | |
spi | spitz | 0.077 | |
dm | diminutive | 0.042 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.040 | |
mtt | mangetout | 0.031 | |
S6k | RPS6-p70-protein kinase | 0.031 | |
EndoGI | Endonuclease G inhibitor | 0.029 | |
norpA | no receptor potential A | 0.028 | |
Ssdp | Sequence-specific single-stranded DNA-binding protein | 0.027 | |
Sema-1a | CG18405 gene product from transcript CG18405-RD | 0.026 | |
rut | rutabaga | 0.024 | |
myoglianin | CG1838 gene product from transcript CG1838-RD | 0.023 | |
Pk61C | Protein kinase 61C | 0.023 | |
rl | rolled | 0.022 | |
Smox | Smad on X | 0.022 | |
so | sine oculis | 0.021 | |
scrib | scribbled | 0.020 | |
mys | myospheroid | 0.020 | |
Snap25 | Synapse protein 25 | 0.020 | |
cher | cheerio | 0.020 | |
yki | yorkie | 0.020 | |
Thor | CG8846 gene product from transcript CG8846-RA | 0.019 | |
CG3004 | CG3004 gene product from transcript CG3004-RA | 0.019 | |
Pten | CG5671 gene product from transcript CG5671-RB | 0.019 | |
CG9510 | CG9510 gene product from transcript CG9510-RC | 0.019 | |
Fak56D | Focal Adhesion Kinase | 0.018 | |
G-oalpha47A | G protein oalpha 47A | 0.018 | |
caz | cabeza | 0.018 | |
FucT6 | alpha1,6-fucosyltransferase | 0.018 | |
ena | enabled | 0.017 | |
repo | reversed polarity | 0.017 | |
rost | rolling stone | 0.017 | |
Gyc76C | Guanylyl cyclase at 76C | 0.017 | |
Csp | Cysteine string protein | 0.016 | |
kon | kon-tiki | 0.016 | |
CdsA | CDP diglyceride synthetase | 0.016 | |
Hcf | Host cell factor | 0.016 | |
hpo | hippo | 0.016 | |
mol | moladietz | 0.016 | |
trx | trithorax | 0.016 | |
RagA | CG11968 gene product from transcript CG11968-RA | 0.016 | |
ninaB | neither inactivation nor afterpotential B | 0.016 | |
hipk | homeodomain interacting protein kinase | 0.015 | |
GstE6 | Glutathione S transferase E6 | 0.015 | |
ninaA | neither inactivation nor afterpotential A | 0.015 | |
inaD | inactivation no afterpotential D | 0.015 | |
katanin-60 | katanin 60 | 0.015 | |
step | steppke | 0.014 | |
wun | wunen | 0.014 | |
scb | scab | 0.014 | |
ex | expanded | 0.014 | |
CG8090 | CG8090 gene product from transcript CG8090-RB | 0.014 | |
stai | stathmin | 0.014 | |
vkg | viking | 0.014 | |
ATP7 | CG1886 gene product from transcript CG1886-RB | 0.014 | |
Rheb | CG1081 gene product from transcript CG1081-RA | 0.014 | |
ImpL2 | Ecdysone-inducible gene L2 | 0.014 | |
Atg18 | Autophagy-specific gene 18 | 0.013 | |
Socs36E | Suppressor of cytokine signaling at 36E | 0.013 | |
hth | homothorax | 0.013 | |
chp | chaoptic | 0.013 | |
CG32528 | CG32528 gene product from transcript CG32528-RA | 0.013 | |
Ank2 | Ankyrin 2 | 0.013 | |
yip2 | yippee interacting protein 2 | 0.013 | |
tkv | thickveins | 0.013 | |
rols | rolling pebbles | 0.013 | |
Gr28b | Gustatory receptor 28b | 0.013 | |
CG17826 | CG17826 gene product from transcript CG17826-RA | 0.013 | |
La | La autoantigen-like | 0.013 | |
CG11581 | CG11581 gene product from transcript CG11581-RA | 0.013 | |
shn | schnurri | 0.013 | |
CG42629 | CG42629 gene product from transcript CG42629-RB | 0.013 | |
LamC | Lamin C | 0.013 | |
ics | icarus | 0.013 | |
her | hermaphrodite | 0.013 | |
mRpS30 | mitochondrial ribosomal protein S30 | 0.013 | |
Spn27A | Serpin 27A | 0.013 | |
Sir2 | CG5216 gene product from transcript CG5216-RA | 0.013 | |
wit | wishful thinking | 0.013 | |
mav | maverick | 0.013 | |
sw | short wing | 0.012 | |
slbo | slow border cells | 0.012 | |
NFAT | NFAT homolog | 0.012 | |
par-1 | CG8201 gene product from transcript CG8201-RA | 0.012 | |
CG31176 | CG31176 gene product from transcript CG31176-RA | 0.012 | |
Vps4 | Vacuolar protein sorting 4 | 0.012 | |
CG9436 | CG9436 gene product from transcript CG9436-RA | 0.012 | |
CG9339 | CG9339 gene product from transcript CG9339-RG | 0.012 | |
AdoR | Adenosine receptor | 0.012 | |
plexB | plexin B | 0.012 | |
trp | transient receptor potential | 0.012 | |
RhoGAP92B | CG4755 gene product from transcript CG4755-RA | 0.012 | |
da | daughterless | 0.012 | |
insc | inscuteable | 0.012 | |
AcCoAS | Acetyl Coenzyme A synthase | 0.012 | |
sqd | squid | 0.012 | |
Adgf-A | Adenosine deaminase-related growth factor A | 0.012 | |
Lnk | CG17367 gene product from transcript CG17367-RC | 0.012 | |
unk | unkempt | 0.012 | |
tws | twins | 0.012 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 1.000 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.995 | |
EGFR | epidermal growth factor receptor | 0.995 | |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.981 | |
FYN | FYN oncogene related to SRC, FGR, YES | 0.978 | |
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.975 | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.970 | |
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.920 | |
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.893 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.856 | |
TEK | TEK tyrosine kinase, endothelial | 0.855 | |
SYK | spleen tyrosine kinase | 0.683 | |
GRB2 | growth factor receptor-bound protein 2 | 0.681 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.680 | |
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.659 | |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.632 | |
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.593 | |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.562 | |
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.493 | |
ENG | endoglin | 0.470 | |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.468 | |
IGF1R | insulin-like growth factor 1 receptor | 0.450 | |
WASL | Wiskott-Aldrich syndrome-like | 0.418 | |
SH2D4A | SH2 domain containing 4A | 0.412 | |
AKR1C2 | aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) | 0.397 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.377 | |
LAT | linker for activation of T cells | 0.350 | |
IL1R1 | interleukin 1 receptor, type I | 0.333 | |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.309 | |
FGFR1 | fibroblast growth factor receptor 1 | 0.306 | |
AKR1C1 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) | 0.282 | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.280 | |
HCK | hemopoietic cell kinase | 0.275 | |
WIPF1 | WAS/WASL interacting protein family, member 1 | 0.274 | |
STK4 | serine/threonine kinase 4 | 0.274 | |
TAL1 | T-cell acute lymphocytic leukemia 1 | 0.268 | |
FKBP1A | FK506 binding protein 1A, 12kDa | 0.257 | |
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.252 | |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.247 | |
IL8 | interleukin 8 | 0.228 | |
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.221 | |
PDCD6IP | programmed cell death 6 interacting protein | 0.217 | |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.208 | |
SPRR2A | small proline-rich protein 2A | 0.206 | |
CCR5 | chemokine (C-C motif) receptor 5 | 0.200 | |
BMP2 | bone morphogenetic protein 2 | 0.191 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.191 | |
ADRB1 | adrenergic, beta-1-, receptor | 0.191 | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.184 | |
MPDZ | multiple PDZ domain protein | 0.182 | |
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.179 | |
GAB1 | GRB2-associated binding protein 1 | 0.177 | |
GUCY2C | guanylate cyclase 2C (heat stable enterotoxin receptor) | 0.177 | |
MAPK8 | mitogen-activated protein kinase 8 | 0.171 | |
CCL2 | chemokine (C-C motif) ligand 2 | 0.171 | |
ZNF746 | zinc finger protein 746 | 0.169 | |
GHR | growth hormone receptor | 0.167 | |
HDAC6 | histone deacetylase 6 | 0.167 | |
CCL4 | chemokine (C-C motif) ligand 4 | 0.165 | |
IRS1 | insulin receptor substrate 1 | 0.164 | |
SMAD7 | SMAD family member 7 | 0.160 | |
PTEN | phosphatase and tensin homolog | 0.160 | |
ARRB1 | arrestin, beta 1 | 0.155 | |
IL6 | interleukin 6 (interferon, beta 2) | 0.153 | |
FGA | fibrinogen alpha chain | 0.152 | |
BCR | breakpoint cluster region | 0.152 | |
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.149 | |
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.149 | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.147 | |
MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.144 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.143 | |
CCL20 | chemokine (C-C motif) ligand 20 | 0.141 | |
ILK | integrin-linked kinase | 0.140 | |
TTR | transthyretin | 0.132 | |
CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.126 | |
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.125 | |
CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.125 | |
NRP1 | neuropilin 1 | 0.124 | |
INSR | insulin receptor | 0.124 | |
NCK1 | NCK adaptor protein 1 | 0.119 | |
GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.117 | |
MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.114 | |
SFN | stratifin | 0.110 | |
PRKCA | protein kinase C, alpha | 0.108 | |
RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.107 | |
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.107 | |
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.101 | |
AKR1C3 | aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) | 0.098 | |
ANGPT2 | angiopoietin 2 | 0.097 | |
CCL8 | chemokine (C-C motif) ligand 8 | 0.097 | |
PDE4DIP | phosphodiesterase 4D interacting protein | 0.096 | |
SNX9 | sorting nexin 9 | 0.095 | |
GRB10 | growth factor receptor-bound protein 10 | 0.095 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.093 | |
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.091 | |
TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.090 | |
LCK | lymphocyte-specific protein tyrosine kinase | 0.089 | |
DLG4 | discs, large homolog 4 (Drosophila) | 0.087 | |
ADORA2A | adenosine A2a receptor | 0.086 | |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.084 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Tnf | tumor necrosis factor (TNF superfamily, member 2) | 0.024 | |
Ddr1 | discoidin domain receptor tyrosine kinase 1 | 0.019 | |
Cyp3a23/3a1 | cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 | 0.018 | |
Il1a | interleukin 1 alpha | 0.016 | |
Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.015 | |
Ccr5 | chemokine (C-C motif) receptor 5 | 0.014 | |
Dbp | D site of albumin promoter (albumin D-box) binding protein | 0.014 | |
Ralgds | ral guanine nucleotide dissociation stimulator | 0.013 | |
Olr1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.010 | |
Pik3r1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.010 | |
Sult2a1 | sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 | 0.010 |