The network for 'mammary gland morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mammary gland morphogenesis

The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.

Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 1.000
Tbx1 T-box 1 0.999
Shh sonic hedgehog 0.995
Bmp4 bone morphogenetic protein 4 0.993
Chrd chordin 0.992
Apc adenomatosis polyposis coli 0.991
Gli2 GLI-Kruppel family member GLI2 0.990
Fgfr1 fibroblast growth factor receptor 1 0.985
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.983
Sox9 SRY-box containing gene 9 0.983
Tbx3 T-box 3 0.981
Nodal nodal 0.979
Fgf10 fibroblast growth factor 10 0.973
Pax2 paired box gene 2 0.969
Pax3 paired box gene 3 0.968
Fgfr3 fibroblast growth factor receptor 3 0.968
Bcl2 B-cell leukemia/lymphoma 2 0.967
Prrx2 paired related homeobox 2 0.966
Trp53 transformation related protein 53 0.965
Smad3 MAD homolog 3 (Drosophila) 0.959
Foxc1 forkhead box C1 0.957
Tgfbr2 transforming growth factor, beta receptor II 0.957
Smad4 MAD homolog 4 (Drosophila) 0.941
Rara retinoic acid receptor, alpha 0.927
Pitx2 paired-like homeodomain transcription factor 2 0.919
Rxra retinoid X receptor alpha 0.917
Ctnnb1 catenin (cadherin associated protein), beta 1 0.916
Prrx1 paired related homeobox 1 0.913
Pitx1 paired-like homeodomain transcription factor 1 0.911
Pax8 paired box gene 8 0.911
Rarg retinoic acid receptor, gamma 0.895
Robo1 roundabout homolog 1 (Drosophila) 0.891
Pten phosphatase and tensin homolog 0.889
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.880
Fgf8 fibroblast growth factor 8 0.874
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.860
Zeb1 zinc finger E-box binding homeobox 1 0.852
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.831
Dlx5 distal-less homeobox 5 0.814
Bmp7 bone morphogenetic protein 7 0.806
Foxn1 forkhead box N1 0.802
Hand2 heart and neural crest derivatives expressed transcript 2 0.753
Hoxa1 homeobox A1 0.748
Slit2 slit homolog 2 (Drosophila) 0.740
Acvr1 activin A receptor, type 1 0.739
Efnb2 ephrin B2 0.738
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.732
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.732
Otx2 orthodenticle homolog 2 (Drosophila) 0.725
Csf1 colony stimulating factor 1 (macrophage) 0.722
Lepr leptin receptor 0.716
Foxc2 forkhead box C2 0.705
Hand1 heart and neural crest derivatives expressed transcript 1 0.699
Gli3 GLI-Kruppel family member GLI3 0.696
Hmx3 H6 homeobox 3 0.695
Ptch1 patched homolog 1 0.685
Stat5b signal transducer and activator of transcription 5B 0.667
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.663
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.653
Tgfb1 transforming growth factor, beta 1 0.622
Alx4 aristaless-like homeobox 4 0.621
Jag1 jagged 1 0.592
Smo smoothened homolog (Drosophila) 0.589
Egfr epidermal growth factor receptor 0.585
Pax9 paired box gene 9 0.581
Skil SKI-like 0.576
Wnt3a wingless-related MMTV integration site 3A 0.556
Tgfb2 transforming growth factor, beta 2 0.551
Slit3 slit homolog 3 (Drosophila) 0.551
Runx2 runt related transcription factor 2 0.545
Eya1 eyes absent 1 homolog (Drosophila) 0.529
Hoxa2 homeobox A2 0.505
Vangl2 vang-like 2 (van gogh, Drosophila) 0.485
Myod1 myogenic differentiation 1 0.482
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.478
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.477
Gdnf glial cell line derived neurotrophic factor 0.471
Ren1 renin 1 structural 0.468
Ret ret proto-oncogene 0.468
Smad6 MAD homolog 6 (Drosophila) 0.458
Gli1 GLI-Kruppel family member GLI1 0.456
Lhx3 LIM homeobox protein 3 0.456
Gata4 GATA binding protein 4 0.448
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.446
Gata6 GATA binding protein 6 0.436
Col4a3 collagen, type IV, alpha 3 0.429
Tcfap2a transcription factor AP-2, alpha 0.429
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.428
Lif leukemia inhibitory factor 0.426
Vdr vitamin D receptor 0.397
Barx1 BarH-like homeobox 1 0.391
Hoxa13 homeobox A13 0.388
Bdnf brain derived neurotrophic factor 0.387
Nf1 neurofibromatosis 1 0.375
Tgfa transforming growth factor alpha 0.366
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.362
Ncoa3 nuclear receptor coactivator 3 0.360
Tbx2 T-box 2 0.358
Stat5a signal transducer and activator of transcription 5A 0.356
Axin1 axin 1 0.354
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
RARA retinoic acid receptor, alpha 0.986
FGFR2 fibroblast growth factor receptor 2 0.982
EGFR epidermal growth factor receptor 0.890
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.890
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.861
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.824
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.816
NCOA1 nuclear receptor coactivator 1 0.764
CREBBP CREB binding protein 0.710
FGFR1 fibroblast growth factor receptor 1 0.621
NCOA2 nuclear receptor coactivator 2 0.581
FGF10 fibroblast growth factor 10 0.549
MEOX2 mesenchyme homeobox 2 0.433
FGF1 fibroblast growth factor 1 (acidic) 0.416
EHF ets homologous factor 0.413
NCOR2 nuclear receptor corepressor 2 0.374
S100A4 S100 calcium binding protein A4 0.372
IL4R interleukin 4 receptor 0.362
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.285
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.269
HR hairless homolog (mouse) 0.265
CAV1 caveolin 1, caveolae protein, 22kDa 0.259
EFNA1 ephrin-A1 0.235
SOX10 SRY (sex determining region Y)-box 10 0.216
FSTL1 follistatin-like 1 0.194
JAK1 Janus kinase 1 0.188
TGFB3 transforming growth factor, beta 3 0.177
TGFB1 transforming growth factor, beta 1 0.174
EP300 E1A binding protein p300 0.172
RXRA retinoid X receptor, alpha 0.169
S100A2 S100 calcium binding protein A2 0.153
TM4SF1 transmembrane 4 L six family member 1 0.146
POU3F2 POU class 3 homeobox 2 0.134
ESR1 estrogen receptor 1 0.132
CUEDC2 CUE domain containing 2 0.130
JDP2 Jun dimerization protein 2 0.129
ENG endoglin 0.122
FGF7 fibroblast growth factor 7 0.113
BCL2L1 BCL2-like 1 0.113
GSK3B glycogen synthase kinase 3 beta 0.111
DAXX death-domain associated protein 0.104
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.086
NCK2 NCK adaptor protein 2 0.083
BAK1 BCL2-antagonist/killer 1 0.079
FHL2 four and a half LIM domains 2 0.077
CCND1 cyclin D1 0.077
CCND3 cyclin D3 0.077
CDK6 cyclin-dependent kinase 6 0.075
HIPK2 homeodomain interacting protein kinase 2 0.075
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.071
KAT2B K(lysine) acetyltransferase 2B 0.068
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.067
FBXW11 F-box and WD repeat domain containing 11 0.067
ESR2 estrogen receptor 2 (ER beta) 0.066
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.064
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.062
IGF1R insulin-like growth factor 1 receptor 0.060
MSX1 msh homeobox 1 0.057
CAPRIN2 caprin family member 2 0.055
ZFYVE9 zinc finger, FYVE domain containing 9 0.054
DCC deleted in colorectal carcinoma 0.054
FGF8 fibroblast growth factor 8 (androgen-induced) 0.054
RUNX1 runt-related transcription factor 1 0.053
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.052
CTTN cortactin 0.051
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.049
BCL3 B-cell CLL/lymphoma 3 0.046
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.046
FZD1 frizzled homolog 1 (Drosophila) 0.045
TRIP6 thyroid hormone receptor interactor 6 0.045
FRS2 fibroblast growth factor receptor substrate 2 0.045
BIK BCL2-interacting killer (apoptosis-inducing) 0.045
FGFR3 fibroblast growth factor receptor 3 0.045
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.044
CAV2 caveolin 2 0.044
GHR growth hormone receptor 0.043
TGFB2 transforming growth factor, beta 2 0.042
GRIP1 glutamate receptor interacting protein 1 0.042
SMAD2 SMAD family member 2 0.042
APC adenomatous polyposis coli 0.042
DDR2 discoidin domain receptor tyrosine kinase 2 0.041
STAT5A signal transducer and activator of transcription 5A 0.041
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.040
TGFBR1 transforming growth factor, beta receptor 1 0.039
OGN osteoglycin 0.039
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.039
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.038
PTPRF protein tyrosine phosphatase, receptor type, F 0.037
STK36 serine/threonine kinase 36 0.036
FGF3 fibroblast growth factor 3 0.036
WNT3A wingless-type MMTV integration site family, member 3A 0.036
SP1 Sp1 transcription factor 0.035
TRRAP transformation/transcription domain-associated protein 0.035
SNAPIN SNAP-associated protein 0.034
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.032
THRA thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) 0.032
BMP2 bone morphogenetic protein 2 0.031
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 0.031
SUFU suppressor of fused homolog (Drosophila) 0.031
PTGIS prostaglandin I2 (prostacyclin) synthase 0.030
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rara retinoic acid receptor, alpha 0.314
Bmp7 bone morphogenetic protein 7 0.047
Capn5 calpain 5 0.045
Ddr1 discoidin domain receptor tyrosine kinase 1 0.042
Vom2r44 vomeronasal 2 receptor 44 0.036
Prrx1 paired related homeobox 1 0.028
Smad3 SMAD family member 3 0.028
Met met proto-oncogene 0.027
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.027
Ctf1 cardiotrophin 1 0.025
Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 0.022
Rarg retinoic acid receptor, gamma 0.022
Fat2 FAT tumor suppressor homolog 2 (Drosophila) 0.022
Gata3 GATA binding protein 3 0.021
Utrn utrophin 0.021
Socs3 suppressor of cytokine signaling 3 0.020
Fgf14 fibroblast growth factor 14 0.019
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.018
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.018
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.018
Hoxc4 homeo box C4 0.017
Bak1 BCL2-antagonist/killer 1 0.016
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.016
Pgr progesterone receptor 0.016
LOC100365106 rCG32755-like 0.015
Col4a5 collagen, type IV, alpha 5 0.015
Sox4 SRY (sex determining region Y)-box 4 0.014
Golim4 golgi integral membrane protein 4 0.014
Fbln5 fibulin 5 0.014
Stxbp2 syntaxin binding protein 2 0.014
Ralgds ral guanine nucleotide dissociation stimulator 0.014
Pdzk1ip1 PDZK1 interacting protein 1 0.014
Dchs1 dachsous 1 (Drosophila) 0.013
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.013
Mmp23 matrix metallopeptidase 23 0.013
Sod3 superoxide dismutase 3, extracellular 0.013
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.012
Ccdc3 coiled-coil domain containing 3 0.012
Bcl2 B-cell CLL/lymphoma 2 0.012
Kitlg KIT ligand 0.012
Myo1d myosin ID 0.012
Shox2 short stature homeobox 2 0.011
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.011
Tmem79 transmembrane protein 79 0.011
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.010
Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.010
Capn1 calpain 1 0.010
Nr2f6 nuclear receptor subfamily 2, group F, member 6 0.010
Plcg2 phospholipase C, gamma 2 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism