The network for 'positive regulation of antimicrobial humoral response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of antimicrobial humoral response

Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.

Mus musculus
Name Description Probability Func Analog Organism
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.998
Ikbkb inhibitor of kappaB kinase beta 0.993
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.991
Ikbkg inhibitor of kappaB kinase gamma 0.979
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.976
Tnf tumor necrosis factor 0.971
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.969
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.814
Lyz2 lysozyme 2 0.785
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.731
Tlr4 toll-like receptor 4 0.639
Bcl3 B-cell leukemia/lymphoma 3 0.442
Cd44 CD44 antigen 0.429
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.390
Cyld cylindromatosis (turban tumor syndrome) 0.323
Cxcl2 chemokine (C-X-C motif) ligand 2 0.291
Pycard PYD and CARD domain containing 0.291
Chuk conserved helix-loop-helix ubiquitous kinase 0.255
Dlx1 distal-less homeobox 1 0.228
Traf6 TNF receptor-associated factor 6 0.224
Il1b interleukin 1 beta 0.220
Igh immunoglobulin heavy chain complex 0.205
Ticam1 toll-like receptor adaptor molecule 1 0.199
Ccl4 chemokine (C-C motif) ligand 4 0.196
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.176
Birc3 baculoviral IAP repeat-containing 3 0.174
Trp53 transformation related protein 53 0.173
Myd88 myeloid differentiation primary response gene 88 0.149
Il18 interleukin 18 0.124
2010106G01Rik RIKEN cDNA 2010106G01 gene 0.121
Casp1 caspase 1 0.119
Gbp2 guanylate binding protein 2 0.104
Socs3 suppressor of cytokine signaling 3 0.093
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.087
Ooep oocyte expressed protein homolog (dog) 0.086
Rag2 recombination activating gene 2 0.084
Tnip1 TNFAIP3 interacting protein 1 0.081
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.075
Aim2 absent in melanoma 2 0.074
Ccr1 chemokine (C-C motif) receptor 1 0.071
Nfkbiz nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.069
Cd40 CD40 antigen 0.065
Gbp3 guanylate binding protein 3 0.064
Socs1 suppressor of cytokine signaling 1 0.062
Cd14 CD14 antigen 0.056
Tbk1 TANK-binding kinase 1 0.051
Stat3 signal transducer and activator of transcription 3 0.050
E2f1 E2F transcription factor 1 0.048
Tax1bp1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.048
Ifi203 interferon activated gene 203 0.048
Irf1 interferon regulatory factor 1 0.048
Il2rg interleukin 2 receptor, gamma chain 0.048
Trp73 transformation related protein 73 0.046
Casp8 caspase 8 0.044
Il1r1 interleukin 1 receptor, type I 0.044
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.044
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.044
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.043
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.040
2410004A20Rik RIKEN cDNA 2410004A20 gene 0.039
Clec4e C-type lectin domain family 4, member e 0.039
Smad1 MAD homolog 1 (Drosophila) 0.039
Cxcl10 chemokine (C-X-C motif) ligand 10 0.038
Adam17 a disintegrin and metallopeptidase domain 17 0.038
Hnf4a hepatic nuclear factor 4, alpha 0.038
Sykb spleen tyrosine kinase 0.037
Tcf7l2 transcription factor 7-like 2, T-cell specific, HMG-box 0.037
Foxp3 forkhead box P3 0.037
Skil SKI-like 0.036
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.036
Gbp7 guanylate binding protein 7 0.036
Stk4 serine/threonine kinase 4 0.036
Rel reticuloendotheliosis oncogene 0.035
Krt27 keratin 27 0.035
Fgl2 fibrinogen-like protein 2 0.033
Mefv Mediterranean fever 0.033
Osmr oncostatin M receptor 0.032
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.032
Cdx1 caudal type homeobox 1 0.032
Wnt7b wingless-related MMTV integration site 7B 0.031
Kcns1 K+ voltage-gated channel, subfamily S, 1 0.031
Snap23 synaptosomal-associated protein 23 0.031
Bcl6 B-cell leukemia/lymphoma 6 0.031
Dnmt1 DNA methyltransferase (cytosine-5) 1 0.031
Mnda myeloid cell nuclear differentiation antigen 0.031
AI607873 expressed sequence AI607873 0.030
Atoh1 atonal homolog 1 (Drosophila) 0.030
Vmn1r53 vomeronasal 1 receptor 53 0.030
Crebbp CREB binding protein 0.029
Clec4d C-type lectin domain family 4, member d 0.029
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.029
Pou3f4 POU domain, class 3, transcription factor 4 0.028
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.028
Mmp13 matrix metallopeptidase 13 0.028
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.028
Bcl10 B-cell leukemia/lymphoma 10 0.028
Irak3 interleukin-1 receptor-associated kinase 3 0.028
Hoxd13 homeobox D13 0.028
Oprm1 opioid receptor, mu 1 0.027
Irgm1 immunity-related GTPase family M member 1 0.027
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 1.000
PGRP-LC Peptidoglycan recognition protein LC 0.997
AttA Attacin-A 0.978
ird5 immune response deficient 5 0.950
DptB Diptericin B 0.941
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.935
Sp7 Serine protease 7 0.862
imd immune deficiency 0.806
Spn28D Serpin 28D 0.800
Spn27A Serpin 27A 0.795
SPE Spatzle-Processing Enzyme 0.780
cact cactus 0.778
PGRP-SA Peptidoglycan recognition protein SA 0.777
spz spatzle 0.776
grass Gram-positive Specific Serine protease 0.736
fon fondue 0.693
key kenny 0.687
Mtk Metchnikowin 0.680
BG4 CG12297 gene product from transcript CG12297-RA 0.532
Dredd Death related ced-3/Nedd2-like protein 0.472
AttC Attacin-C 0.438
bcd bicoid 0.353
osk oskar 0.313
Spn1 Serine protease inhibitor 1 0.282
Myd88 CG2078 gene product from transcript CG2078-RA 0.271
CG7910 CG7910 gene product from transcript CG7910-RA 0.189
Irc Immune-regulated catalase 0.179
ird1 immune response deficient 1 0.174
Dpt Diptericin 0.137
pirk poor Imd response upon knock-in 0.121
18w 18 wheeler 0.114
pll pelle 0.110
AGO2 Argonaute 2 0.096
Drs Drosomycin 0.095
lilli lilliputian 0.083
CG15917 CG15917 gene product from transcript CG15917-RA 0.077
CG32185 CG32185 gene product from transcript CG32185-RA 0.076
dhd deadhead 0.069
CecC Cecropin C 0.066
l(3)mbn lethal (3) malignant blood neoplasm 0.062
nec necrotic 0.061
Spn77Ba Serpin 77Ba 0.060
PGRP-LF Peptidoglycan recognition protein LF 0.057
PGRP-LB Peptidoglycan recognition protein LB 0.056
CecA2 Cecropin A2 0.046
nub nubbin 0.041
Traf4 TNF-receptor-associated factor 4 0.041
eater CG6124 gene product from transcript CG6124-RB 0.041
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.040
CG18594 CG18594 gene product from transcript CG18594-RA 0.039
CG12766 CG12766 gene product from transcript CG12766-RA 0.039
ed echinoid 0.039
cora coracle 0.038
klu klumpfuss 0.038
psh persephone 0.037
Mpk2 CG5475 gene product from transcript CG5475-RB 0.034
tsl torso-like 0.033
Nc Nedd2-like caspase 0.033
upd2 unpaired 2 0.030
CG15800 CG15800 gene product from transcript CG15800-RA 0.030
mirr mirror 0.028
CG13641 CG13641 gene product from transcript CG13641-RA 0.028
CG6361 CG6361 gene product from transcript CG6361-RA 0.028
CG15065 CG15065 gene product from transcript CG15065-RA 0.028
spirit Serine Protease Immune Response Integrator 0.028
CG13422 CG13422 gene product from transcript CG13422-RA 0.027
GNBP1 Gram-negative bacteria binding protein 1 0.027
Toll-7 CG8595 gene product from transcript CG8595-RA 0.027
CecA1 Cecropin A1 0.027
PGRP-LE Peptidoglycan recognition protein LE 0.026
CG8586 CG8586 gene product from transcript CG8586-RA 0.024
Obp99d Odorant-binding protein 99d 0.024
CG16772 CG16772 gene product from transcript CG16772-RA 0.023
sdt stardust 0.023
CecB Cecropin B 0.022
gsb gooseberry 0.022
bic bicaudal 0.022
Ice CG7788 gene product from transcript CG7788-RA 0.021
ns1 nucleostemin 1 0.021
CG13962 CG13962 gene product from transcript CG13962-RA 0.021
GNBP3 Gram-negative bacteria binding protein 3 0.021
Duox Dual oxidase 0.021
Spn88Eb Serpin 88Eb 0.021
CG9989 CG9989 gene product from transcript CG9989-RA 0.020
IM1 Immune induced molecule 1 0.020
CG9372 CG9372 gene product from transcript CG9372-RA 0.020
eg eagle 0.020
Parg Poly(ADP-ribose) glycohydrolase 0.020
CG12496 CG12496 gene product from transcript CG12496-RA 0.020
CG4757 CG4757 gene product from transcript CG4757-RA 0.020
exu exuperantia 0.019
upd3 unpaired 3 0.019
crol crooked legs 0.019
r2d2 CG7138 gene product from transcript CG7138-RB 0.019
CG31326 CG31326 gene product from transcript CG31326-RA 0.018
TepIII Thiolester containing protein III 0.018
Hey Hairy/E(spl)-related with YRPW motif 0.018
Pabp2 CG2163 gene product from transcript CG2163-RA 0.018
Traf6 TNF-receptor-associated factor 6 0.018
modSP modular serine protease 0.017
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Homo sapiens
Name Description Probability Func Analog Organism
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 1.000
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.000
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.998
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.998
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.986
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.937
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.914
CHUK conserved helix-loop-helix ubiquitous kinase 0.851
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.764
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.760
BCL3 B-cell CLL/lymphoma 3 0.734
NLRC4 NLR family, CARD domain containing 4 0.641
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.588
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.306
PAX3 paired box 3 0.303
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.211
CRADD CASP2 and RIPK1 domain containing adaptor with death domain 0.144
ELF4 E74-like factor 4 (ets domain transcription factor) 0.126
IRAK1 interleukin-1 receptor-associated kinase 1 0.069
SOX10 SRY (sex determining region Y)-box 10 0.064
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.054
BIRC3 baculoviral IAP repeat containing 3 0.047
IRAK2 interleukin-1 receptor-associated kinase 2 0.040
SOCS1 suppressor of cytokine signaling 1 0.039
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.038
TLR4 toll-like receptor 4 0.038
LRDD leucine-rich repeats and death domain containing 0.038
RIPK2 receptor-interacting serine-threonine kinase 2 0.034
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.033
SETD7 SET domain containing (lysine methyltransferase) 7 0.031
TAB3 TGF-beta activated kinase 1/MAP3K7 binding protein 3 0.030
TNIP2 TNFAIP3 interacting protein 2 0.028
IRAK4 interleukin-1 receptor-associated kinase 4 0.023
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.022
PYCARD PYD and CARD domain containing 0.020
RAI1 retinoic acid induced 1 0.019
TLR2 toll-like receptor 2 0.019
IRAK3 interleukin-1 receptor-associated kinase 3 0.018
SOX21 SRY (sex determining region Y)-box 21 0.017
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.016
FKBP5 FK506 binding protein 5 0.016
SQRDL sulfide quinone reductase-like (yeast) 0.015
EP300 E1A binding protein p300 0.015
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.014
ZC3H12A zinc finger CCCH-type containing 12A 0.013
IL18 interleukin 18 (interferon-gamma-inducing factor) 0.013
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.013
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.013
SIRT6 sirtuin 6 0.013
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.012
STAP2 signal transducing adaptor family member 2 0.012
GBP2 guanylate binding protein 2, interferon-inducible 0.012
RXRA retinoid X receptor, alpha 0.011
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.011
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 0.011
POU3F3 POU class 3 homeobox 3 0.011
JUNB jun B proto-oncogene 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism