Process View
The network for 'positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Tgfb2 | transforming growth factor, beta 2 | 1.000 | |
Acvr1 | activin A receptor, type 1 | 0.997 | |
Bmp4 | bone morphogenetic protein 4 | 0.995 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.991 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.987 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.985 | |
Shh | sonic hedgehog | 0.982 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.976 | |
Vegfa | vascular endothelial growth factor A | 0.971 | |
Jag1 | jagged 1 | 0.928 | |
Gata4 | GATA binding protein 4 | 0.917 | |
Gpc3 | glypican 3 | 0.907 | |
Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.895 | |
Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.880 | |
Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.864 | |
Fgf8 | fibroblast growth factor 8 | 0.856 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.845 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.843 | |
Tbx1 | T-box 1 | 0.841 | |
Efnb2 | ephrin B2 | 0.798 | |
Pax3 | paired box gene 3 | 0.786 | |
Gata6 | GATA binding protein 6 | 0.778 | |
Foxc1 | forkhead box C1 | 0.767 | |
Pten | phosphatase and tensin homolog | 0.766 | |
Adam19 | a disintegrin and metallopeptidase domain 19 (meltrin beta) | 0.757 | |
Foxa2 | forkhead box A2 | 0.736 | |
Nodal | nodal | 0.734 | |
Apc | adenomatosis polyposis coli | 0.733 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.729 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.720 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.695 | |
Meox2 | mesenchyme homeobox 2 | 0.667 | |
Bmp7 | bone morphogenetic protein 7 | 0.665 | |
Gli3 | GLI-Kruppel family member GLI3 | 0.663 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.624 | |
Axin1 | axin 1 | 0.622 | |
Zic3 | zinc finger protein of the cerebellum 3 | 0.620 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.611 | |
Chrd | chordin | 0.610 | |
Lrp2 | low density lipoprotein receptor-related protein 2 | 0.610 | |
Nf1 | neurofibromatosis 1 | 0.577 | |
Gdnf | glial cell line derived neurotrophic factor | 0.566 | |
Tcf21 | transcription factor 21 | 0.563 | |
Nkx2-1 | NK2 homeobox 1 | 0.558 | |
Ece1 | endothelin converting enzyme 1 | 0.558 | |
Thbs1 | thrombospondin 1 | 0.540 | |
Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.539 | |
Itgb3 | integrin beta 3 | 0.535 | |
Prrx1 | paired related homeobox 1 | 0.534 | |
Ntf3 | neurotrophin 3 | 0.534 | |
Prrx2 | paired related homeobox 2 | 0.515 | |
Foxh1 | forkhead box H1 | 0.512 | |
Smad7 | MAD homolog 7 (Drosophila) | 0.506 | |
Smad1 | MAD homolog 1 (Drosophila) | 0.493 | |
Sfrp2 | secreted frizzled-related protein 2 | 0.479 | |
Zfpm2 | zinc finger protein, multitype 2 | 0.464 | |
Rb1 | retinoblastoma 1 | 0.462 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.459 | |
Bmp5 | bone morphogenetic protein 5 | 0.442 | |
Hif1a | hypoxia inducible factor 1, alpha subunit | 0.439 | |
Eng | endoglin | 0.433 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.407 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.405 | |
Adam9 | a disintegrin and metallopeptidase domain 9 (meltrin gamma) | 0.383 | |
Smad6 | MAD homolog 6 (Drosophila) | 0.383 | |
Fst | follistatin | 0.370 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.364 | |
Nog | noggin | 0.357 | |
Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.350 | |
Gdf1 | growth differentiation factor 1 | 0.343 | |
Atoh7 | atonal homolog 7 (Drosophila) | 0.330 | |
Tbx3 | T-box 3 | 0.327 | |
Braf | Braf transforming gene | 0.322 | |
Gja1 | gap junction protein, alpha 1 | 0.318 | |
Fgf10 | fibroblast growth factor 10 | 0.310 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.310 | |
She | src homology 2 domain-containing transforming protein E | 0.305 | |
Tbx2 | T-box 2 | 0.303 | |
Smo | smoothened homolog (Drosophila) | 0.303 | |
Gli1 | GLI-Kruppel family member GLI1 | 0.301 | |
Sox4 | SRY-box containing gene 4 | 0.283 | |
Sox2 | SRY-box containing gene 2 | 0.282 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.277 | |
Wt1 | Wilms tumor 1 homolog | 0.264 | |
Ltbp1 | latent transforming growth factor beta binding protein 1 | 0.261 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.260 | |
Axin2 | axin2 | 0.259 | |
Tcfap2a | transcription factor AP-2, alpha | 0.258 | |
Sema6d | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D | 0.249 | |
Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.249 | |
Msx2 | homeobox, msh-like 2 | 0.237 | |
Acvrl1 | activin A receptor, type II-like 1 | 0.233 | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.231 | |
Lef1 | lymphoid enhancer binding factor 1 | 0.230 | |
Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.228 | |
Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.221 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.220 | |
Epas1 | endothelial PAS domain protein 1 | 0.211 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.209 | |
Kdr | kinase insert domain protein receptor | 0.206 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
daf-1 | Protein DAF-1 | 0.494 | |
daf-2 | Protein DAF-2 | 0.340 | |
egl-18 | Protein EGL-18 | 0.262 | |
daf-4 | Protein DAF-4 | 0.239 | |
lin-36 | Protein LIN-36 | 0.237 | |
bar-1 | Protein BAR-1 | 0.228 | |
daf-11 | Protein DAF-11 | 0.176 | |
tax-2 | Protein TAX-2 | 0.157 | |
gcy-22 | Protein GCY-22 | 0.096 | |
tax-4 | Protein TAX-4 | 0.060 | |
che-1 | Protein CHE-1 | 0.055 | |
ten-1 | Protein TEN-1 | 0.055 | |
pop-1 | Protein POP-1 | 0.038 | |
sel-12 | Protein SEL-12 | 0.037 | |
hlh-2 | Protein HLH-2 | 0.035 | |
egl-15 | Protein EGL-15 | 0.032 | |
unc-73 | Protein UNC-73 | 0.029 | |
elt-6 | Protein ELT-6 | 0.022 | |
egl-46 | Protein EGL-46 | 0.020 | |
let-756 | Protein LET-756 | 0.018 | |
daf-12 | Protein DAF-12 | 0.018 | |
sulp-2 | Protein SULP-2 | 0.017 | |
C48E7.1 | Protein C48E7.1 | 0.015 | |
let-23 | Protein LET-23 | 0.015 | |
osm-3 | Protein OSM-3 | 0.014 | |
eya-1 | Protein EYA-1 | 0.014 | |
pha-4 | Protein PHA-4 | 0.013 | |
T14E8.2 | Protein T14E8.2 | 0.013 | |
mom-2 | Protein MOM-2 | 0.013 | |
alp-1 | Protein ALP-1 | 0.012 | |
lin-17 | Protein LIN-17 | 0.012 | |
T23F4.2 | Protein T23F4.2 | 0.012 | |
unc-95 | Protein UNC-95 | 0.012 | |
scrm-1 | Protein SCRM-1 | 0.012 | |
kin-3 | Protein KIN-3 | 0.012 | |
plc-3 | Protein PLC-3 | 0.012 | |
sma-10 | Protein SMA-10 | 0.011 | |
daf-7 | Protein DAF-7 | 0.011 | |
lag-2 | Protein LAG-2 | 0.011 | |
pqn-71 | Protein PQN-71 | 0.011 | |
din-1 | Protein DIN-1 | 0.011 | |
R05G6.10 | Protein R05G6.10 | 0.011 | |
let-60 | Protein LET-60 | 0.011 | |
CELE_ZK550.4 | Protein ZK550.4 | 0.010 | |
K09E4.2 | Protein K09E4.2 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
bmp2b | bone morphogenetic protein 2b | 0.754 | |
acvr2a | activin receptor IIa | 0.147 | |
bmp4 | bone morphogenetic protein 4 | 0.136 | |
mmp2 | matrix metalloproteinase 2 | 0.083 | |
vent | ventral expressed homeobox | 0.058 | |
fgfr1b | fibroblast growth factor receptor 1b | 0.056 | |
edn1 | endothelin 1 | 0.056 | |
chd | chordin | 0.056 | |
bmpr2a | bone morphogenetic protein receptor, type II a (serine/threonine kinase) | 0.053 | |
lhx2b | LIM homeobox 2b | 0.052 | |
igf3 | insulin-like growth factor 3 | 0.050 | |
acvr2b | activin receptor IIb | 0.049 | |
tgfb3 | transforming growth factor, beta 3 | 0.047 | |
ntla | no tail a | 0.043 | |
arhgef7b | Rho guanine nucleotide exchange factor (GEF) 7b | 0.034 | |
spry4 | sprouty (Drosophila) homolog 4 | 0.032 | |
tcf7l2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.031 | |
kita | kit receptor a | 0.026 | |
satb2 | SATB homeobox 2 | 0.026 | |
slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 0.025 | |
bmp7b | bone morphogenetic protein 7b | 0.023 | |
gdf9 | growth differentiation factor 9 | 0.023 | |
tgfb2 | transforming growth factor, beta 2 | 0.021 | |
plcg1 | phospholipase C, gamma 1 | 0.021 | |
ccm2 | cerebral cavernous malformation 2 | 0.020 | |
LOC557062 | hypothetical protein LOC557062 | 0.020 | |
robo1 | roundabout homolog 1 | 0.019 | |
notum3 | notum 3 | 0.019 | |
fmnl2a | formin-like 2a | 0.018 | |
unc5b | unc-5 homolog B (C. elegans) | 0.017 | |
fras1 | Fraser syndrome 1 | 0.017 | |
jag1b | jagged 1b | 0.016 | |
gro1 | groucho 1 | 0.016 | |
rxrbb | retinoid x receptor, beta b | 0.015 | |
rest | RE1-silencing transcription factor | 0.015 | |
gro2 | groucho 2 | 0.015 | |
dusp6 | dual specificity phosphatase 6 | 0.015 | |
ctsl1b | cathepsin L, 1 b | 0.014 | |
fli1a | friend leukemia integration 1a | 0.014 | |
cpla2 | cytosolic phospholipase a2 | 0.014 | |
rxrba | retinoid x receptor, beta a | 0.014 | |
ihha | Indian hedgehog homolog a | 0.014 | |
gsc | goosecoid | 0.013 | |
inha | inhibin, alpha | 0.013 | |
plxnd1 | plexin D1 | 0.013 | |
fshr | follicle stimulating hormone receptor | 0.013 | |
zgc:158603 | zgc:158603 | 0.013 | |
og9x | OG9 homeobox gene | 0.012 | |
ryk | receptor-like tyrosine kinase | 0.012 | |
sox32 | SRY-box containing gene 32 | 0.012 | |
aplnrb | apelin receptor b | 0.012 | |
dusp5 | dual specificity phosphatase 5 | 0.012 | |
slc4a2a | solute carrier family 4, anion exchanger, member 2a | 0.012 | |
barx2 | BarH-like homeobox 2 | 0.012 | |
ythdf1 | YTH domain family, member 1 | 0.011 | |
drl | draculin | 0.011 | |
wu:fj39b01 | wu:fj39b01 | 0.011 | |
chd7 | chromodomain helicase DNA binding protein 7 | 0.011 | |
angptl2 | angiopoietin-like 2 | 0.011 | |
phex | phosphate regulating gene with homologues to endopeptidases on the X chromosome | 0.011 | |
gadd45g | growth arrest and DNA-damage-inducible, gamma | 0.011 | |
hsd17b1 | hydroxysteroid (17-beta) dehydrogenase 1 | 0.011 | |
fn1 | fibronectin 1 | 0.011 | |
nkd1 | naked cuticle homolog 1 (Drosophila) | 0.011 | |
bcl2 | B-cell leukemia/lymphoma 2 | 0.011 | |
si:ch211-212m21.5 | si:ch211-212m21.5 | 0.011 | |
lmo4a | LIM domain only 4a | 0.010 | |
si:ch73-60e21.1 | si:ch73-60e21.1 | 0.010 | |
osr1 | odd-skipped related 1 (Drosophila) | 0.010 | |
wu:fv91b12 | wu:fv91b12 | 0.010 | |
cpa1 | carboxypeptidase A1 (pancreatic) | 0.010 | |
ptgs2a | prostaglandin-endoperoxide synthase 2a | 0.010 | |
lmx1b.2 | LIM homeobox transcription factor 1, beta 2 | 0.010 | |
gpc4 | glypican 4 | 0.010 | |
hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Dad | Daughters against dpp | 0.753 | |
Mad | Mothers against dpp | 0.652 | |
E(spl) | Enhancer of split | 0.569 | |
gbb | glass bottom boat | 0.541 | |
HLHmbeta | E(spl) region transcript mbeta | 0.456 | |
HLHmdelta | E(spl) region transcript mdelta | 0.385 | |
Med | Medea | 0.379 | |
gro | groucho | 0.348 | |
HLHmgamma | E(spl) region transcript mgamma | 0.308 | |
shn | schnurri | 0.300 | |
HLHm7 | E(spl) region transcript m7 | 0.297 | |
tld | tolloid | 0.295 | |
daw | dawdle | 0.263 | |
ci | cubitus interruptus | 0.255 | |
HLHm3 | E(spl) region transcript m3 | 0.229 | |
HLHm5 | E(spl) region transcript m5 | 0.163 | |
stck | steamer duck | 0.151 | |
malpha | E(spl) region transcript malpha | 0.133 | |
G-oalpha47A | G protein oalpha 47A | 0.129 | |
sog | short gastrulation | 0.127 | |
Smox | Smad on X | 0.124 | |
tok | tolkin | 0.118 | |
babo | baboon | 0.114 | |
mbc | myoblast city | 0.092 | |
myoglianin | CG1838 gene product from transcript CG1838-RD | 0.089 | |
Tl | Toll | 0.084 | |
tkv | thickveins | 0.074 | |
EcR | Ecdysone receptor | 0.059 | |
noc | no ocelli | 0.054 | |
ush | u-shaped | 0.053 | |
stmA | stambha A | 0.053 | |
Tom | Twin of m4 | 0.052 | |
emc | extra macrochaetae | 0.049 | |
shot | short stop | 0.046 | |
Plc21C | Phospholipase C at 21C | 0.045 | |
Su(H) | Suppressor of Hairless | 0.044 | |
sax | saxophone | 0.044 | |
Egfr | Epidermal growth factor receptor | 0.043 | |
dpp | decapentaplegic | 0.043 | |
usp | ultraspiracle | 0.040 | |
sc | scute | 0.038 | |
dlg1 | discs large 1 | 0.036 | |
m2 | E(spl) region transcript m2 | 0.036 | |
18w | 18 wheeler | 0.034 | |
aux | auxillin | 0.033 | |
wit | wishful thinking | 0.032 | |
LamC | Lamin C | 0.031 | |
Ubqn | Ubiquilin | 0.030 | |
kek5 | kekkon5 | 0.029 | |
scw | screw | 0.028 | |
Sema-1a | CG18405 gene product from transcript CG18405-RD | 0.027 | |
Kr-h1 | Kruppel homolog 1 | 0.026 | |
Snap | Soluble NSF attachment protein | 0.026 | |
bib | big brain | 0.026 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.025 | |
unc-104 | CG8566 gene product from transcript CG8566-RB | 0.023 | |
Sulf1 | Sulfated | 0.022 | |
comt | comatose | 0.021 | |
Pvr | PDGF- and VEGF-receptor related | 0.021 | |
cv-2 | crossveinless 2 | 0.020 | |
kni | knirps | 0.020 | |
Pk92B | Protein kinase at 92B | 0.020 | |
Dap160 | Dynamin associated protein 160 | 0.020 | |
Eip74EF | Ecdysone-induced protein 74EF | 0.019 | |
Mmp1 | Matrix metalloproteinase 1 | 0.018 | |
neur | neuralized | 0.018 | |
tsg | twisted gastrulation | 0.018 | |
sd | scalloped | 0.018 | |
Nrg | Neuroglian | 0.017 | |
m4 | E(spl) region transcript m4 | 0.017 | |
TBPH | CG10327 gene product from transcript CG10327-RC | 0.017 | |
beta-Spec | beta Spectrin | 0.016 | |
kay | kayak | 0.016 | |
CG13604 | CG13604 gene product from transcript CG13604-RD | 0.016 | |
CG6194 | CG6194 gene product from transcript CG6194-RA | 0.015 | |
Sara | Smad anchor for receptor activation | 0.015 | |
O-fut1 | O-fucosyltransferase 1 | 0.015 | |
Pde8 | Phosphodiesterase 8 | 0.015 | |
hig | hikaru genki | 0.015 | |
svr | silver | 0.014 | |
BobA | Brother of Bearded A | 0.014 | |
byn | brachyenteron | 0.014 | |
mew | multiple edematous wings | 0.014 | |
sfl | sulfateless | 0.014 | |
CG16972 | CG16972 gene product from transcript CG16972-RA | 0.014 | |
Dl | Delta | 0.014 | |
Fs | Follistatin | 0.013 | |
cora | coracle | 0.013 | |
tap | target of Poxn | 0.013 | |
Myo31DF | Myosin 31DF | 0.013 | |
ex | expanded | 0.013 | |
Cyp18a1 | Cytochrome P450-18a1 | 0.013 | |
bowl | brother of odd with entrails limited | 0.013 | |
wun | wunen | 0.013 | |
insc | inscuteable | 0.012 | |
LanA | Laminin A | 0.012 | |
tup | tailup | 0.012 | |
spen | split ends | 0.012 | |
ase | asense | 0.012 | |
l(2)gl | lethal (2) giant larvae | 0.012 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
SMAD7 | SMAD family member 7 | 1.000 | |
SMAD3 | SMAD family member 3 | 1.000 | |
SMAD2 | SMAD family member 2 | 0.995 | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.976 | |
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.963 | |
BMPR1A | bone morphogenetic protein receptor, type IA | 0.927 | |
SP1 | Sp1 transcription factor | 0.883 | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.845 | |
NRP1 | neuropilin 1 | 0.830 | |
TGFB1 | transforming growth factor, beta 1 | 0.787 | |
NOTCH1 | notch 1 | 0.784 | |
JAG1 | jagged 1 | 0.668 | |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.648 | |
EP300 | E1A binding protein p300 | 0.615 | |
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.596 | |
FN1 | fibronectin 1 | 0.590 | |
CTGF | connective tissue growth factor | 0.572 | |
BMP2 | bone morphogenetic protein 2 | 0.513 | |
FSTL1 | follistatin-like 1 | 0.499 | |
SNIP1 | Smad nuclear interacting protein 1 | 0.490 | |
WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.414 | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.360 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.323 | |
ACVR1 | activin A receptor, type I | 0.301 | |
FKBP1A | FK506 binding protein 1A, 12kDa | 0.298 | |
TGFB3 | transforming growth factor, beta 3 | 0.275 | |
BMPR1B | bone morphogenetic protein receptor, type IB | 0.265 | |
FBXL12 | F-box and leucine-rich repeat protein 12 | 0.255 | |
NCK2 | NCK adaptor protein 2 | 0.244 | |
CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.241 | |
FOXD3 | forkhead box D3 | 0.227 | |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.222 | |
TPBG | trophoblast glycoprotein | 0.191 | |
GDF5 | growth differentiation factor 5 | 0.182 | |
RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.175 | |
ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.168 | |
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.163 | |
DLG1 | discs, large homolog 1 (Drosophila) | 0.151 | |
RNF5 | ring finger protein 5 | 0.145 | |
PIAS4 | protein inhibitor of activated STAT, 4 | 0.132 | |
NOG | noggin | 0.129 | |
TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | 0.125 | |
PARVA | parvin, alpha | 0.124 | |
XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.116 | |
STRADA | STE20-related kinase adaptor alpha | 0.111 | |
PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.111 | |
HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.108 | |
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.099 | |
SMAD1 | SMAD family member 1 | 0.097 | |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.096 | |
BBS10 | Bardet-Biedl syndrome 10 | 0.086 | |
CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.084 | |
TGFBR1 | transforming growth factor, beta receptor 1 | 0.082 | |
WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.082 | |
MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.079 | |
SKIL | SKI-like oncogene | 0.071 | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.069 | |
HOXA1 | homeobox A1 | 0.066 | |
TADA3 | transcriptional adaptor 3 | 0.066 | |
NCOR2 | nuclear receptor corepressor 2 | 0.062 | |
LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.060 | |
LPXN | leupaxin | 0.060 | |
HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.059 | |
NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.059 | |
SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.059 | |
RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.057 | |
SIRT1 | sirtuin 1 | 0.057 | |
MAML1 | mastermind-like 1 (Drosophila) | 0.056 | |
SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.051 | |
TP53BP2 | tumor protein p53 binding protein, 2 | 0.051 | |
ZEB2 | zinc finger E-box binding homeobox 2 | 0.050 | |
SMAD6 | SMAD family member 6 | 0.048 | |
QKI | quaking homolog, KH domain RNA binding (mouse) | 0.047 | |
BGN | biglycan | 0.047 | |
VCL | vinculin | 0.047 | |
LIMD1 | LIM domains containing 1 | 0.046 | |
FBLN1 | fibulin 1 | 0.045 | |
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.045 | |
FILIP1L | filamin A interacting protein 1-like | 0.045 | |
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.045 | |
MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.045 | |
ING2 | inhibitor of growth family, member 2 | 0.044 | |
THBS1 | thrombospondin 1 | 0.044 | |
PIAS1 | protein inhibitor of activated STAT, 1 | 0.044 | |
TGFB2 | transforming growth factor, beta 2 | 0.044 | |
FBXL15 | F-box and leucine-rich repeat protein 15 | 0.044 | |
SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.042 | |
TOX4 | TOX high mobility group box family member 4 | 0.042 | |
CXXC5 | CXXC finger protein 5 | 0.041 | |
ACVR1B | activin A receptor, type IB | 0.041 | |
NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.041 | |
SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.040 | |
CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.039 | |
SCARB2 | scavenger receptor class B, member 2 | 0.039 | |
MEST | mesoderm specific transcript homolog (mouse) | 0.038 | |
TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.038 | |
SFRP4 | secreted frizzled-related protein 4 | 0.038 | |
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.037 | |
ACVR2B | activin A receptor, type IIB | 0.037 | |
EGR1 | early growth response 1 | 0.037 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Smad7 | SMAD family member 7 | 0.198 | |
Il12b | interleukin 12B | 0.086 | |
Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.074 | |
Tal1 | T-cell acute lymphocytic leukemia 1 | 0.052 | |
Psen1 | presenilin 1 | 0.048 | |
Jak2 | Janus kinase 2 | 0.038 | |
Ets1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.038 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.033 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.030 | |
Pacs1 | phosphofurin acidic cluster sorting protein 1 | 0.026 | |
Tceb3 | transcription elongation factor B (SIII), polypeptide 3 | 0.024 | |
Dlgap2 | discs, large (Drosophila) homolog-associated protein 2 | 0.023 | |
Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.023 | |
Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.023 | |
Mmp23 | matrix metallopeptidase 23 | 0.022 | |
Serpinh1 | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 0.022 | |
Wt1 | Wilms tumor 1 | 0.022 | |
Tgfbr3 | transforming growth factor, beta receptor III | 0.021 | |
Rara | retinoic acid receptor, alpha | 0.020 | |
Cish | cytokine inducible SH2-containing protein | 0.020 | |
Sox17 | SRY (sex determining region Y)-box 17 | 0.019 | |
Lama5 | laminin, alpha 5 | 0.019 | |
Gja5 | gap junction protein, alpha 5 | 0.019 | |
Prkch | protein kinase C, eta | 0.019 | |
Il1r1 | interleukin 1 receptor, type I | 0.019 | |
Acta2 | smooth muscle alpha-actin | 0.016 | |
Atp7b | ATPase, Cu++ transporting, beta polypeptide | 0.016 | |
Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.016 | |
Unc5b | unc-5 homolog B (C. elegans) | 0.016 | |
Ggt5 | gamma-glutamyltransferase 5 | 0.015 | |
Ece1 | endothelin converting enzyme 1 | 0.015 | |
Znf503 | zinc finger protein 503 | 0.015 | |
St3gal3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | 0.015 | |
Met | met proto-oncogene | 0.015 | |
Elk3 | ELK3, ETS-domain protein | 0.014 | |
Socs2 | suppressor of cytokine signaling 2 | 0.014 | |
Rin1 | Ras and Rab interactor 1 | 0.013 | |
Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.013 | |
Fbln5 | fibulin 5 | 0.012 | |
Pde4a | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 0.012 | |
Efnb1 | ephrin B1 | 0.012 | |
Rab14 | RAB14, member RAS oncogene family | 0.011 | |
Prkar2a | protein kinase, cAMP dependent regulatory, type II alpha | 0.011 | |
Ptp4a1 | protein tyrosine phosphatase type IVA, member 1 | 0.011 | |
Klf2 | Kruppel-like factor 2 (lung) | 0.011 | |
Ednrb | endothelin receptor type B | 0.011 | |
Shc2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.011 | |
Stx2 | syntaxin 2 | 0.011 | |
Kif27 | kinesin family member 27 | 0.011 | |
Arnt | aryl hydrocarbon receptor nuclear translocator | 0.011 | |
Stag3 | stromal antigen 3 | 0.010 | |
Slc12a4 | solute carrier family 12 (potassium/chloride transporters), member 4 | 0.010 | |
Lnpep | leucyl/cystinyl aminopeptidase | 0.010 |