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Homo sapiens

26 genes annotated in human

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regulation of striated muscle tissue development

GO:0016202

Any process that modulates the frequency, rate or extent of striated muscle development.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of striated muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of striated muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.999	Mouse
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.999
FGF1	fibroblast growth factor 1 (acidic)	0.993	Human
JAG1	jagged 1	0.992
NOTCH1	notch 1	0.979
ESR1	estrogen receptor 1	0.942
FSTL1	follistatin-like 1	0.908
TBX5	T-box 5	0.902
EP300	E1A binding protein p300	0.890
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.886	Mouse
HDAC4	histone deacetylase 4	0.801	Mouse
JUN	jun proto-oncogene	0.786
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.705
FGF10	fibroblast growth factor 10	0.644	Human
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.519
MEF2C	myocyte enhancer factor 2C	0.519
NCOR2	nuclear receptor corepressor 2	0.459
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.418
MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	0.416
NCOA3	nuclear receptor coactivator 3	0.385
LRP6	low density lipoprotein receptor-related protein 6	0.368	Mouse
BMPR1A	bone morphogenetic protein receptor, type IA	0.349
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.343
ENG	endoglin	0.336
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.330
MYOD1	myogenic differentiation 1	0.314
TTN	titin	0.272
RB1	retinoblastoma 1	0.269
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.254
SETD8	SET domain containing (lysine methyltransferase) 8	0.248
AR	androgen receptor	0.232
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.213
TGFB3	transforming growth factor, beta 3	0.196
MEF2A	myocyte enhancer factor 2A	0.194	Human
CREBBP	CREB binding protein	0.184
CNOT8	CCR4-NOT transcription complex, subunit 8	0.183
CDK2	cyclin-dependent kinase 2	0.180
IGF2	insulin-like growth factor 2 (somatomedin A)	0.167
HDAC6	histone deacetylase 6	0.155
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.149	Rat
NOTCH3	notch 3	0.143	Human
INO80B	INO80 complex subunit B	0.138
AXIN1	axin 1	0.135
PLCG1	phospholipase C, gamma 1	0.133
H3F3C	H3 histone, family 3C	0.129
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.128
C5orf41	chromosome 5 open reading frame 41	0.128
FZD1	frizzled homolog 1 (Drosophila)	0.119
TCF4	transcription factor 4	0.119
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.117
SIRT1	sirtuin 1	0.116
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.107
SMAD7	SMAD family member 7	0.105
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.105
CDK1	cyclin-dependent kinase 1	0.097	Rat
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.093	Human Mouse
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.091
HDAC9	histone deacetylase 9	0.088	Mouse
HIC1	hypermethylated in cancer 1	0.087
FGF7	fibroblast growth factor 7	0.084	Human
DLL1	delta-like 1 (Drosophila)	0.083
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.081
GATA4	GATA binding protein 4	0.080	Mouse
JAG2	jagged 2	0.079
BCL2L1	BCL2-like 1	0.075
STK3	serine/threonine kinase 3	0.075
CABLES1	Cdk5 and Abl enzyme substrate 1	0.073
SATB2	SATB homeobox 2	0.073
KAT2B	K(lysine) acetyltransferase 2B	0.070
EPAS1	endothelial PAS domain protein 1	0.070
DDR2	discoidin domain receptor tyrosine kinase 2	0.069
NCK2	NCK adaptor protein 2	0.069
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.069
FBLN1	fibulin 1	0.064
BTF3	basic transcription factor 3	0.064
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.061
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.061
MAML1	mastermind-like 1 (Drosophila)	0.059
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.058
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.058
WWOX	WW domain containing oxidoreductase	0.058
BCL6	B-cell CLL/lymphoma 6	0.058
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.057
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.055
TP53BP2	tumor protein p53 binding protein, 2	0.054
CLOCK	clock homolog (mouse)	0.054
HDAC1	histone deacetylase 1	0.052
CXCL11	chemokine (C-X-C motif) ligand 11	0.050
FGF8	fibroblast growth factor 8 (androgen-induced)	0.050
ZHX1	zinc fingers and homeoboxes 1	0.047
DCN	decorin	0.047
DBP	D site of albumin promoter (albumin D-box) binding protein	0.047
ARRDC3	arrestin domain containing 3	0.046
APP	amyloid beta (A4) precursor protein	0.044
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.044
EGLN1	egl nine homolog 1 (C. elegans)	0.043
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.043
FGF3	fibroblast growth factor 3	0.042
MKL1	megakaryoblastic leukemia (translocation) 1	0.042	Human
IRS1	insulin receptor substrate 1	0.042
PARVA	parvin, alpha	0.042
IQGAP1	IQ motif containing GTPase activating protein 1	0.042
KLF13	Kruppel-like factor 13	0.041
ADAM12	ADAM metallopeptidase domain 12	0.041
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.041
GSK3B	glycogen synthase kinase 3 beta	0.040
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.039
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.039
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.036
CTGF	connective tissue growth factor	0.035
EGLN3	egl nine homolog 3 (C. elegans)	0.035
BMP7	bone morphogenetic protein 7	0.034
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.033
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.033
LBX1	ladybird homeobox 1	0.032
DPP4	dipeptidyl-peptidase 4	0.032
SMAD1	SMAD family member 1	0.032
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.031
CCNA2	cyclin A2	0.031
HSPG2	heparan sulfate proteoglycan 2	0.031
PNRC1	proline-rich nuclear receptor coactivator 1	0.031
DDIT4	DNA-damage-inducible transcript 4	0.030
ATN1	atrophin 1	0.030
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.029
MDFI	MyoD family inhibitor	0.029
TRIM63	tripartite motif containing 63	0.028
FGF2	fibroblast growth factor 2 (basic)	0.028
CNOT7	CCR4-NOT transcription complex, subunit 7	0.028
WNT3A	wingless-type MMTV integration site family, member 3A	0.028
CCNE1	cyclin E1	0.027
MYOCD	myocardin	0.027
ARID1A	AT rich interactive domain 1A (SWI-like)	0.027
TRO	trophinin	0.027
VHL	von Hippel-Lindau tumor suppressor	0.027
FGFR3	fibroblast growth factor receptor 3	0.027
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.027
NCOR1	nuclear receptor corepressor 1	0.027
FZD8	frizzled homolog 8 (Drosophila)	0.026
MYOG	myogenin (myogenic factor 4)	0.026	Mouse
CCNB2	cyclin B2	0.024
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.024
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.024
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.024
SPOP	speckle-type POZ protein	0.024
BMP2	bone morphogenetic protein 2	0.024
HPCAL4	hippocalcin like 4	0.024
SIX1	SIX homeobox 1	0.024	Mouse
LIMS1	LIM and senescent cell antigen-like domains 1	0.023
CHD4	chromodomain helicase DNA binding protein 4	0.023
THBS1	thrombospondin 1	0.023
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.023
NEURL4	neuralized homolog 4 (Drosophila)	0.022
BTG1	B-cell translocation gene 1, anti-proliferative	0.022
HMGA1	high mobility group AT-hook 1	0.022
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.022
RICTOR	RPTOR independent companion of MTOR, complex 2	0.022
MKL2	MKL/myocardin-like 2	0.022
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.021
TOP1	topoisomerase (DNA) I	0.021
TGFB2	transforming growth factor, beta 2	0.021	Human
ADSS	adenylosuccinate synthase	0.021
MAPK8	mitogen-activated protein kinase 8	0.021
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.021
HMGA2	high mobility group AT-hook 2	0.020
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.020
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.020
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.020
SMAD6	SMAD family member 6	0.020
CKS2	CDC28 protein kinase regulatory subunit 2	0.020
BCL2	B-cell CLL/lymphoma 2	0.020	Mouse
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.020
NOTCH2	notch 2	0.020	Human
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.020
CDH5	cadherin 5, type 2 (vascular endothelium)	0.019
ATXN1	ataxin 1	0.019
DMPK	dystrophia myotonica-protein kinase	0.019
LRRK2	leucine-rich repeat kinase 2	0.019
FOXA2	forkhead box A2	0.019
YAP1	Yes-associated protein 1	0.019
PRDM8	PR domain containing 8	0.019
KRT5	keratin 5	0.019
FGF4	fibroblast growth factor 4	0.019	Human
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.019
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.018
TCAP	titin-cap (telethonin)	0.018
PRKCA	protein kinase C, alpha	0.018
E2F1	E2F transcription factor 1	0.017
TBX1	T-box 1	0.017	Human
NOTCH2NL	notch 2 N-terminal like	0.017
TBC1D10A	TBC1 domain family, member 10A	0.017
NCOA1	nuclear receptor coactivator 1	0.017
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.017
PTRF	polymerase I and transcript release factor	0.017
DUSP1	dual specificity phosphatase 1	0.017
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.017
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.017
FZD7	frizzled homolog 7 (Drosophila)	0.017
FGFR1	fibroblast growth factor receptor 1	0.017	Mouse
ZBTB4	zinc finger and BTB domain containing 4	0.016
FGF6	fibroblast growth factor 6	0.016	Human
FRS2	fibroblast growth factor receptor substrate 2	0.016
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.016
PARVB	parvin, beta	0.016
SEC16A	SEC16 homolog A (S. cerevisiae)	0.016
FOXC1	forkhead box C1	0.016
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.016
ITGB1BP3	integrin beta 1 binding protein 3	0.016
OBSL1	obscurin-like 1	0.016
WNT10A	wingless-type MMTV integration site family, member 10A	0.016
FZD2	frizzled homolog 2 (Drosophila)	0.016
TGFBR1	transforming growth factor, beta receptor 1	0.016
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.016
FUNDC2	FUN14 domain containing 2	0.015
NOG	noggin	0.015	Mouse
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.015
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.015
SS18	synovial sarcoma translocation, chromosome 18	0.015
GAS1	growth arrest-specific 1	0.015
BBX	bobby sox homolog (Drosophila)	0.015
TTR	transthyretin	0.015
KRT15	keratin 15	0.015
COASY	CoA synthase	0.015
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.015
LIMK1	LIM domain kinase 1	0.015
RSRC2	arginine/serine-rich coiled-coil 2	0.015
PABPC1	poly(A) binding protein, cytoplasmic 1	0.014
IGF2R	insulin-like growth factor 2 receptor	0.014
RARB	retinoic acid receptor, beta	0.014
HAND2	heart and neural crest derivatives expressed 2	0.014
INVS	inversin	0.014
WNT1	wingless-type MMTV integration site family, member 1	0.014	Human
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.014
KIAA1217	KIAA1217	0.014
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.014
SIX2	SIX homeobox 2	0.014
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.014
BNC1	basonuclin 1	0.013
DLG2	discs, large homolog 2 (Drosophila)	0.013
SMAD4	SMAD family member 4	0.013
FOXF1	forkhead box F1	0.013
PKP4	plakophilin 4	0.013
PLCE1	phospholipase C, epsilon 1	0.013
SFRP1	secreted frizzled-related protein 1	0.013
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.013
RBM4B	RNA binding motif protein 4B	0.013
IGFBP5	insulin-like growth factor binding protein 5	0.013	Human
CXCR3	chemokine (C-X-C motif) receptor 3	0.013
TNS4	tensin 4	0.013
KLF9	Kruppel-like factor 9	0.013
MAPK1	mitogen-activated protein kinase 1	0.013
NRP1	neuropilin 1	0.013
CRYAB	crystallin, alpha B	0.013
KRT6C	keratin 6C	0.013
TGFBR3	transforming growth factor, beta receptor III	0.013
SFRP5	secreted frizzled-related protein 5	0.013
NPAS2	neuronal PAS domain protein 2	0.013
FOXL1	forkhead box L1	0.013
GATA5	GATA binding protein 5	0.013
RARA	retinoic acid receptor, alpha	0.012
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.012	Human
ALX4	ALX homeobox 4	0.012
CNOT1	CCR4-NOT transcription complex, subunit 1	0.012
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.012
GDNF	glial cell derived neurotrophic factor	0.012
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.012
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.012
MRC2	mannose receptor, C type 2	0.012
KLF5	Kruppel-like factor 5 (intestinal)	0.012
HES1	hairy and enhancer of split 1, (Drosophila)	0.012
HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14	0.012
IRX4	iroquois homeobox 4	0.012
BDNF	brain-derived neurotrophic factor	0.012
RBM4	RNA binding motif protein 4	0.012
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.012	Human
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.012
GPC4	glypican 4	0.011
COL1A1	collagen, type I, alpha 1	0.011
POU4F3	POU class 4 homeobox 3	0.011
RUNX3	runt-related transcription factor 3	0.011
JUND	jun D proto-oncogene	0.011
FST	follistatin	0.011
EPHA3	EPH receptor A3	0.011
KANK2	KN motif and ankyrin repeat domains 2	0.011
DHH	desert hedgehog	0.011
COL6A1	collagen, type VI, alpha 1	0.011
FOXF2	forkhead box F2	0.011
GABPB2	GA binding protein transcription factor, beta subunit 2	0.011
SIM2	single-minded homolog 2 (Drosophila)	0.011
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.011
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.011
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.011
EYA1	eyes absent homolog 1 (Drosophila)	0.011
FKBP8	FK506 binding protein 8, 38kDa	0.011
AXIN2	axin 2	0.011
LHX5	LIM homeobox 5	0.011
TLX2	T-cell leukemia homeobox 2	0.011
NEUROG1	neurogenin 1	0.011
DLL4	delta-like 4 (Drosophila)	0.010
ZFYVE9	zinc finger, FYVE domain containing 9	0.010
SLIT2	slit homolog 2 (Drosophila)	0.010
FOXD3	forkhead box D3	0.010
TNIK	TRAF2 and NCK interacting kinase	0.010
MCPH1	microcephalin 1	0.010
PAX8	paired box 8	0.010
MBP	myelin basic protein	0.010
WNT3	wingless-type MMTV integration site family, member 3	0.010
SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	0.010