IMP

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Homo sapiens

26 genes annotated in human

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regulation of muscle tissue development

GO:1901861

Any process that modulates the frequency, rate or extent of muscle tissue development.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of muscle tissue development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of muscle tissue development" (in gray)

Name	Description	Probability	Func Analog Organism
EP300	E1A binding protein p300	0.996
FGFR2	fibroblast growth factor receptor 2	0.992	Mouse
JAG1	jagged 1	0.987
NOTCH1	notch 1	0.985
ESR1	estrogen receptor 1	0.922
FGF1	fibroblast growth factor 1 (acidic)	0.901	Human
TBX5	T-box 5	0.890
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.721
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.697	Rat
FSTL1	follistatin-like 1	0.644
TTN	titin	0.556
FGF10	fibroblast growth factor 10	0.535	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.503	Mouse
SETD8	SET domain containing (lysine methyltransferase) 8	0.402
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.327
TRIM63	tripartite motif containing 63	0.302
HDAC4	histone deacetylase 4	0.297	Mouse
MEF2A	myocyte enhancer factor 2A	0.288	Human
JUN	jun proto-oncogene	0.270
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.261
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.257
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.253
ESRRG	estrogen-related receptor gamma	0.242
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.232
TJP1	tight junction protein 1 (zona occludens 1)	0.227
MEF2C	myocyte enhancer factor 2C	0.217
LRP6	low density lipoprotein receptor-related protein 6	0.191	Mouse
BMP2	bone morphogenetic protein 2	0.171
NOTCH3	notch 3	0.169	Human
TGFB3	transforming growth factor, beta 3	0.167
TGFB1	transforming growth factor, beta 1	0.156
BCL6	B-cell CLL/lymphoma 6	0.140
NCOA3	nuclear receptor coactivator 3	0.137
GSK3B	glycogen synthase kinase 3 beta	0.135
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.133
SIRT1	sirtuin 1	0.132
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.131
BMPR1A	bone morphogenetic protein receptor, type IA	0.131
NCOR2	nuclear receptor corepressor 2	0.128
ENG	endoglin	0.126
PLCG1	phospholipase C, gamma 1	0.121
NCOR1	nuclear receptor corepressor 1	0.118
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.102	Human Mouse
STK3	serine/threonine kinase 3	0.098
WWOX	WW domain containing oxidoreductase	0.097
IGF2	insulin-like growth factor 2 (somatomedin A)	0.097
CLOCK	clock homolog (mouse)	0.095
MYOD1	myogenic differentiation 1	0.095
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.091
SMAD7	SMAD family member 7	0.090
FZD1	frizzled homolog 1 (Drosophila)	0.082
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.081
FBLN1	fibulin 1	0.079
PPARG	peroxisome proliferator-activated receptor gamma	0.076
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.075
BCL2L1	BCL2-like 1	0.075
HNF4A	hepatocyte nuclear factor 4, alpha	0.075
ADAM12	ADAM metallopeptidase domain 12	0.073
CXCL11	chemokine (C-X-C motif) ligand 11	0.071
FGF8	fibroblast growth factor 8 (androgen-induced)	0.070
HDAC9	histone deacetylase 9	0.068	Mouse
DLL1	delta-like 1 (Drosophila)	0.067
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.064
FGFR1	fibroblast growth factor receptor 1	0.064	Mouse
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.063
CNOT8	CCR4-NOT transcription complex, subunit 8	0.063
PARVA	parvin, alpha	0.063
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.062
DUSP1	dual specificity phosphatase 1	0.061
RB1	retinoblastoma 1	0.060
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.058
JAG2	jagged 2	0.056
SMAD1	SMAD family member 1	0.054
CDK1	cyclin-dependent kinase 1	0.054	Rat
TCF4	transcription factor 4	0.053
NCK2	NCK adaptor protein 2	0.050
FGF2	fibroblast growth factor 2 (basic)	0.050
C5orf41	chromosome 5 open reading frame 41	0.050
MAML1	mastermind-like 1 (Drosophila)	0.050
LIMS1	LIM and senescent cell antigen-like domains 1	0.048
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.048
SF1	splicing factor 1	0.048
TP53	tumor protein p53	0.046	Human
CDK2	cyclin-dependent kinase 2	0.046
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.045
EGFR	epidermal growth factor receptor	0.044
ATF3	activating transcription factor 3	0.044
APP	amyloid beta (A4) precursor protein	0.044
ARRDC3	arrestin domain containing 3	0.044
ATXN1L	ataxin 1-like	0.042
KLF5	Kruppel-like factor 5 (intestinal)	0.042
INO80B	INO80 complex subunit B	0.042
RARA	retinoic acid receptor, alpha	0.041
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.041
H3F3C	H3 histone, family 3C	0.040
DBP	D site of albumin promoter (albumin D-box) binding protein	0.039
PNRC1	proline-rich nuclear receptor coactivator 1	0.038
SATB2	SATB homeobox 2	0.038
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.037	Mouse
BTG1	B-cell translocation gene 1, anti-proliferative	0.037
WNT1	wingless-type MMTV integration site family, member 1	0.033	Human
CABLES1	Cdk5 and Abl enzyme substrate 1	0.033
CTGF	connective tissue growth factor	0.033
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.033
HSPG2	heparan sulfate proteoglycan 2	0.033
MDFI	MyoD family inhibitor	0.031
FST	follistatin	0.030
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.030
BMP7	bone morphogenetic protein 7	0.030
HBP1	HMG-box transcription factor 1	0.029
CREBBP	CREB binding protein	0.029
FGF7	fibroblast growth factor 7	0.029	Human
KLF9	Kruppel-like factor 9	0.028
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.027
DLG2	discs, large homolog 2 (Drosophila)	0.027
WNT3A	wingless-type MMTV integration site family, member 3A	0.026
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.026
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.025
FGFR3	fibroblast growth factor receptor 3	0.025
QKI	quaking homolog, KH domain RNA binding (mouse)	0.025
BTG2	BTG family, member 2	0.025	Human
KAT2B	K(lysine) acetyltransferase 2B	0.025
ATN1	atrophin 1	0.025
AR	androgen receptor	0.025
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.025
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.025
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.024
SEC16A	SEC16 homolog A (S. cerevisiae)	0.024
DDR2	discoidin domain receptor tyrosine kinase 2	0.024
FGF3	fibroblast growth factor 3	0.024
AXIN1	axin 1	0.024
NEB	nebulin	0.024
TGFB2	transforming growth factor, beta 2	0.024	Human
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.023
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.023
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.023
FGF4	fibroblast growth factor 4	0.023	Human
THBS1	thrombospondin 1	0.022
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.022
AHR	aryl hydrocarbon receptor	0.022
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.022
TTR	transthyretin	0.022
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.022
YAP1	Yes-associated protein 1	0.022
GABARAP	GABA(A) receptor-associated protein	0.022
PDGFC	platelet derived growth factor C	0.021
FZD8	frizzled homolog 8 (Drosophila)	0.020
GATA4	GATA binding protein 4	0.020	Mouse
KRT5	keratin 5	0.020
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.019
HPCAL4	hippocalcin like 4	0.019
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.019
HMGA2	high mobility group AT-hook 2	0.019
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.019
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.019
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.018
TCAP	titin-cap (telethonin)	0.018
FZD7	frizzled homolog 7 (Drosophila)	0.018
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.018
HDAC1	histone deacetylase 1	0.018
MUC1	mucin 1, cell surface associated	0.018
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.018
HES1	hairy and enhancer of split 1, (Drosophila)	0.018
FN1	fibronectin 1	0.018
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.018
NOTCH2NL	notch 2 N-terminal like	0.018
ASB13	ankyrin repeat and SOCS box containing 13	0.018
STK4	serine/threonine kinase 4	0.017
TBX1	T-box 1	0.017	Human
DDIT4	DNA-damage-inducible transcript 4	0.017
LBX1	ladybird homeobox 1	0.017
ALX4	ALX homeobox 4	0.017
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.017
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.017
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.017
KRT6C	keratin 6C	0.016
FRS2	fibroblast growth factor receptor substrate 2	0.016
NCOA1	nuclear receptor coactivator 1	0.016
TXNIP	thioredoxin interacting protein	0.016
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.016
ADRBK1	adrenergic, beta, receptor kinase 1	0.016
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.016
OBSL1	obscurin-like 1	0.016
NRP1	neuropilin 1	0.016
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.016
COL1A1	collagen, type I, alpha 1	0.016
NOTCH2	notch 2	0.016	Human
TGFBR1	transforming growth factor, beta receptor 1	0.016
TRO	trophinin	0.015
MAPK1	mitogen-activated protein kinase 1	0.015
KLF13	Kruppel-like factor 13	0.015
TOP1	topoisomerase (DNA) I	0.015
FGF6	fibroblast growth factor 6	0.015	Human
CCND1	cyclin D1	0.015
RBM4	RNA binding motif protein 4	0.015
DCN	decorin	0.015
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.015
SMAD6	SMAD family member 6	0.015
E2F1	E2F transcription factor 1	0.015
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.015
DPP4	dipeptidyl-peptidase 4	0.015
BDNF	brain-derived neurotrophic factor	0.015
KRT15	keratin 15	0.014
MKL1	megakaryoblastic leukemia (translocation) 1	0.014	Human
IGFBP5	insulin-like growth factor binding protein 5	0.014	Human
FOXA2	forkhead box A2	0.014
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.014	Human
CXCR3	chemokine (C-X-C motif) receptor 3	0.014
FUNDC2	FUN14 domain containing 2	0.014
PROX1	prospero homeobox 1	0.014
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.014
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.014	Human
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.014
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.014
HDAC3	histone deacetylase 3	0.014
BTF3	basic transcription factor 3	0.014
KLHL24	kelch-like 24 (Drosophila)	0.013
TRIM43	tripartite motif containing 43	0.013
NPAS2	neuronal PAS domain protein 2	0.013
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.013
SOX11	SRY (sex determining region Y)-box 11	0.013
IGF2R	insulin-like growth factor 2 receptor	0.013
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.013
COASY	CoA synthase	0.013
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.013
BMP4	bone morphogenetic protein 4	0.013
PRDM8	PR domain containing 8	0.013
WNT3	wingless-type MMTV integration site family, member 3	0.013
PLCE1	phospholipase C, epsilon 1	0.013
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.012
KANK2	KN motif and ankyrin repeat domains 2	0.012
UBD	ubiquitin D	0.012
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.012
EYA1	eyes absent homolog 1 (Drosophila)	0.012
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012	Mouse
CNOT7	CCR4-NOT transcription complex, subunit 7	0.012
IQGAP1	IQ motif containing GTPase activating protein 1	0.012
NPAS1	neuronal PAS domain protein 1	0.012
GAS1	growth arrest-specific 1	0.012
HDAC6	histone deacetylase 6	0.012
FHL1	four and a half LIM domains 1	0.012
PPARA	peroxisome proliferator-activated receptor alpha	0.011
TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.011
EPAS1	endothelial PAS domain protein 1	0.011
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.011
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.011
EDN1	endothelin 1	0.011
ARNT	aryl hydrocarbon receptor nuclear translocator	0.011
ARID1A	AT rich interactive domain 1A (SWI-like)	0.011
WNT11	wingless-type MMTV integration site family, member 11	0.011
EPHA3	EPH receptor A3	0.011
EFNB2	ephrin-B2	0.011	Mouse
EIF1	eukaryotic translation initiation factor 1	0.011
PARVB	parvin, beta	0.011
RARB	retinoic acid receptor, beta	0.011
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.011
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.011
HAND2	heart and neural crest derivatives expressed 2	0.011
SIM2	single-minded homolog 2 (Drosophila)	0.011
FILIP1L	filamin A interacting protein 1-like	0.011
HOXD12	homeobox D12	0.011	Fly
NOV	nephroblastoma overexpressed gene	0.011
IRX4	iroquois homeobox 4	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011	Rat
PTK6	PTK6 protein tyrosine kinase 6	0.011
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.011
GATAD2B	GATA zinc finger domain containing 2B	0.011
CDH5	cadherin 5, type 2 (vascular endothelium)	0.010
CYLD	cylindromatosis (turban tumor syndrome)	0.010
EGR1	early growth response 1	0.010
PYY	peptide YY	0.010
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.010
TDGF1	teratocarcinoma-derived growth factor 1	0.010
GSC	goosecoid homeobox	0.010
FKBP8	FK506 binding protein 8, 38kDa	0.010
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.010
RICTOR	RPTOR independent companion of MTOR, complex 2	0.010
PRKCA	protein kinase C, alpha	0.010
GATA5	GATA binding protein 5	0.010
SFRP1	secreted frizzled-related protein 1	0.010
ITGB1BP3	integrin beta 1 binding protein 3	0.010
ZEB2	zinc finger E-box binding homeobox 2	0.010
DHH	desert hedgehog	0.010
IGF1	insulin-like growth factor 1 (somatomedin C)	0.010
IFNG	interferon, gamma	0.010
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.010
COL2A1	collagen, type II, alpha 1	0.010