IMP

Process View

Homo sapiens

19 genes annotated in human

kidney morphogenesis

Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "kidney morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "kidney morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	1.000
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.982
FGF1	fibroblast growth factor 1 (acidic)	0.894
FGFR1	fibroblast growth factor receptor 1	0.840
KLHL3	kelch-like 3 (Drosophila)	0.812
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.785
WNK4	WNK lysine deficient protein kinase 4	0.776
FSTL1	follistatin-like 1	0.705
SMAD3	SMAD family member 3	0.662
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.648
BMPR1A	bone morphogenetic protein receptor, type IA	0.631
CUL3	cullin 3	0.613
MEIS2	Meis homeobox 2	0.574
DAPK1	death-associated protein kinase 1	0.543
MEIS1	Meis homeobox 1	0.542
ADAM17	ADAM metallopeptidase domain 17	0.523
MEOX1	mesenchyme homeobox 1	0.506
CCNE1	cyclin E1	0.506
EGR2	early growth response 2	0.499	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.497
KLHL12	kelch-like 12 (Drosophila)	0.481	Human
BMP7	bone morphogenetic protein 7	0.464	Mouse
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.451
FGF10	fibroblast growth factor 10	0.431	Human
NKX2-1	NK2 homeobox 1	0.396
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.389
FGF8	fibroblast growth factor 8 (androgen-induced)	0.359
SMAD2	SMAD family member 2	0.355
SOX2	SRY (sex determining region Y)-box 2	0.337
NOG	noggin	0.331	Mouse
AKAP11	A kinase (PRKA) anchor protein 11	0.302
MSN	moesin	0.274
GLIS2	GLIS family zinc finger 2	0.273
RB1	retinoblastoma 1	0.266
FGF4	fibroblast growth factor 4	0.252	Human
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.234
BCL2L1	BCL2-like 1	0.226
PBK	PDZ binding kinase	0.220
TIMP3	TIMP metallopeptidase inhibitor 3	0.220
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.202
FGF18	fibroblast growth factor 18	0.197
KLHL2	kelch-like 2, Mayven (Drosophila)	0.193	Human
PAX8	paired box 8	0.185
PJA1	praja ring finger 1	0.178
BMP2	bone morphogenetic protein 2	0.166	Human Mouse
MAGED2	melanoma antigen family D, 2	0.162
COL2A1	collagen, type II, alpha 1	0.159
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.148
GSK3B	glycogen synthase kinase 3 beta	0.146
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.140
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.140
HOXB5	homeobox B5	0.139
BMP4	bone morphogenetic protein 4	0.132
PGF	placental growth factor	0.130	Mouse
HOXA10	homeobox A10	0.110
PARVA	parvin, alpha	0.105
TP53BP2	tumor protein p53 binding protein, 2	0.102
ARNT	aryl hydrocarbon receptor nuclear translocator	0.094
FOXA2	forkhead box A2	0.093
FGF7	fibroblast growth factor 7	0.085	Human
FGFR3	fibroblast growth factor receptor 3	0.085
CTGF	connective tissue growth factor	0.082
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.078
TRPV5	transient receptor potential cation channel, subfamily V, member 5	0.076
HNF1B	HNF1 homeobox B	0.073
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.072
E2F3	E2F transcription factor 3	0.070
WNT1	wingless-type MMTV integration site family, member 1	0.069	Human Mouse Fly
EGR3	early growth response 3	0.068	Human
SFRP1	secreted frizzled-related protein 1	0.066
HMGA2	high mobility group AT-hook 2	0.066
PAX2	paired box 2	0.065
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.065
COL7A1	collagen, type VII, alpha 1	0.064
FBXW7	F-box and WD repeat domain containing 7	0.063
HNF1A	HNF1 homeobox A	0.063	Human
WNT7A	wingless-type MMTV integration site family, member 7A	0.061	Human
MARCKSL1	MARCKS-like 1	0.059
SOX1	SRY (sex determining region Y)-box 1	0.058
SNAI1	snail homolog 1 (Drosophila)	0.055
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.055
CUX1	cut-like homeobox 1	0.055	Fly
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.054
SMAD9	SMAD family member 9	0.053
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.052
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.051
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.051
THBS1	thrombospondin 1	0.051
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.049
NGFR	nerve growth factor receptor	0.048
TP53	tumor protein p53	0.047
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.047
LMO4	LIM domain only 4	0.045
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.045
ENG	endoglin	0.045
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.044
GDNF	glial cell derived neurotrophic factor	0.044
FGF2	fibroblast growth factor 2 (basic)	0.043
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.043
TGFBR1	transforming growth factor, beta receptor 1	0.043
FOXC1	forkhead box C1	0.043
CDK2	cyclin-dependent kinase 2	0.042
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.042
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.041
PDX1	pancreatic and duodenal homeobox 1	0.040
PAX3	paired box 3	0.040
FGF3	fibroblast growth factor 3	0.040	Human
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.040
INHBB	inhibin, beta B	0.040
TGFB2	transforming growth factor, beta 2	0.039
TSC22D4	TSC22 domain family, member 4	0.039
CLDN4	claudin 4	0.038
TAOK1	TAO kinase 1	0.038
SIM2	single-minded homolog 2 (Drosophila)	0.038
MAP1B	microtubule-associated protein 1B	0.037
MYOD1	myogenic differentiation 1	0.035
LBX1	ladybird homeobox 1	0.035
PAX7	paired box 7	0.032
LAT	linker for activation of T cells	0.032
CALCA	calcitonin-related polypeptide alpha	0.031
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.031
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.031
GAS1	growth arrest-specific 1	0.030
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.030
TCF4	transcription factor 4	0.029
PRMT6	protein arginine methyltransferase 6	0.029
SPOP	speckle-type POZ protein	0.029
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.028
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.028
HNF4A	hepatocyte nuclear factor 4, alpha	0.028
FOXD3	forkhead box D3	0.027
NFIB	nuclear factor I/B	0.027
AKIP1	A kinase (PRKA) interacting protein 1	0.027
IRX4	iroquois homeobox 4	0.026
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.026
ZMYND10	zinc finger, MYND-type containing 10	0.026
SOX9	SRY (sex determining region Y)-box 9	0.026	Mouse
OTX2	orthodenticle homeobox 2	0.026
TBX2	T-box 2	0.025
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.025
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.024
TEAD4	TEA domain family member 4	0.024
NOTCH1	notch 1	0.024
NEUROG2	neurogenin 2	0.024
WNT3	wingless-type MMTV integration site family, member 3	0.024	Human
MNX1	motor neuron and pancreas homeobox 1	0.023
SOCS1	suppressor of cytokine signaling 1	0.023
PROX1	prospero homeobox 1	0.023
WNT10A	wingless-type MMTV integration site family, member 10A	0.022	Human
IHH	Indian hedgehog	0.022
MED28	mediator complex subunit 28	0.022
CLDN7	claudin 7	0.021
FOXF1	forkhead box F1	0.021
HOXD13	homeobox D13	0.021
WNK1	WNK lysine deficient protein kinase 1	0.021	Human
LRP6	low density lipoprotein receptor-related protein 6	0.021
ATF7IP	activating transcription factor 7 interacting protein	0.020
MAPT	microtubule-associated protein tau	0.020
HMX1	H6 family homeobox 1	0.020
HES2	hairy and enhancer of split 2 (Drosophila)	0.020
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.020
CADM4	cell adhesion molecule 4	0.020
AQP5	aquaporin 5	0.020
EYA2	eyes absent homolog 2 (Drosophila)	0.020
SIRT6	sirtuin 6	0.020
SETD7	SET domain containing (lysine methyltransferase) 7	0.020
SSR1	signal sequence receptor, alpha	0.020
SOX11	SRY (sex determining region Y)-box 11	0.020
DLX4	distal-less homeobox 4	0.019
PLCG1	phospholipase C, gamma 1	0.019
FZD7	frizzled homolog 7 (Drosophila)	0.019
FRS2	fibroblast growth factor receptor substrate 2	0.019
DUSP6	dual specificity phosphatase 6	0.019
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.019
WNT11	wingless-type MMTV integration site family, member 11	0.019
PDGFA	platelet-derived growth factor alpha polypeptide	0.019
CXXC5	CXXC finger protein 5	0.019
SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	0.019
PDE4DIP	phosphodiesterase 4D interacting protein	0.019
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.019
LMX1B	LIM homeobox transcription factor 1, beta	0.019
NCOA7	nuclear receptor coactivator 7	0.019
IGFBP5	insulin-like growth factor binding protein 5	0.018
HBEGF	heparin-binding EGF-like growth factor	0.018
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.018
OXSR1	oxidative-stress responsive 1	0.018
FAS	Fas (TNF receptor superfamily, member 6)	0.018
CDK6	cyclin-dependent kinase 6	0.018
TAL1	T-cell acute lymphocytic leukemia 1	0.018
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.018
IRX5	iroquois homeobox 5	0.018
PURA	purine-rich element binding protein A	0.017
SIX2	SIX homeobox 2	0.017	Mouse
RUNX1	runt-related transcription factor 1	0.017
FST	follistatin	0.017
HS3ST6	heparan sulfate (glucosamine) 3-O-sulfotransferase 6	0.017
RYR2	ryanodine receptor 2 (cardiac)	0.017
ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2	0.017
CDX2	caudal type homeobox 2	0.017
DGCR14	DiGeorge syndrome critical region gene 14	0.017
FGF19	fibroblast growth factor 19	0.017
WIF1	WNT inhibitory factor 1	0.017
WNT9B	wingless-type MMTV integration site family, member 9B	0.017	Human
NCOA6	nuclear receptor coactivator 6	0.017
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.017
CRHR1	corticotropin releasing hormone receptor 1	0.017
CYR61	cysteine-rich, angiogenic inducer, 61	0.017
CLDN1	claudin 1	0.017
EYA1	eyes absent homolog 1 (Drosophila)	0.016
DDR2	discoidin domain receptor tyrosine kinase 2	0.016
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.016
WNT6	wingless-type MMTV integration site family, member 6	0.016	Human
NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2	0.016
VSX1	visual system homeobox 1	0.016
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.016
PYY	peptide YY	0.015
ACAN	aggrecan	0.015
NPHP1	nephronophthisis 1 (juvenile)	0.015
HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	0.015
HOXC5	homeobox C5	0.015
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.015
OTP	orthopedia homeobox	0.015
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.015
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.015
PCBD2	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2	0.014
KAT2B	K(lysine) acetyltransferase 2B	0.014
HOXD9	homeobox D9	0.014
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.014
SDC2	syndecan 2	0.014
RAB5B	RAB5B, member RAS oncogene family	0.014
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.014
LIMS1	LIM and senescent cell antigen-like domains 1	0.014
MSX1	msh homeobox 1	0.014
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.014
T	T, brachyury homolog (mouse)	0.013
LHX9	LIM homeobox 9	0.013
CREBBP	CREB binding protein	0.013
HOXB1	homeobox B1	0.013
NKD2	naked cuticle homolog 2 (Drosophila)	0.013
HOXA11	homeobox A11	0.013	Mouse
EGR1	early growth response 1	0.013	Human
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.013
FZD10	frizzled homolog 10 (Drosophila)	0.013
FOXF2	forkhead box F2	0.013
CRLF1	cytokine receptor-like factor 1	0.013
HOXD11	homeobox D11	0.013	Mouse
ITGA8	integrin, alpha 8	0.013
SLIT2	slit homolog 2 (Drosophila)	0.013
SMO	smoothened homolog (Drosophila)	0.013
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.013
TGFB3	transforming growth factor, beta 3	0.013
THBS2	thrombospondin 2	0.013
HOXC10	homeobox C10	0.013
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.013
NKX3-2	NK3 homeobox 2	0.013
UNC119B	unc-119 homolog B (C. elegans)	0.013
PRRX2	paired related homeobox 2	0.013
EPHB3	EPH receptor B3	0.012
FOXN4	forkhead box N4	0.012
DNAJC1	DnaJ (Hsp40) homolog, subfamily C, member 1	0.012
EID1	EP300 interacting inhibitor of differentiation 1	0.012
C5orf13	chromosome 5 open reading frame 13	0.012
EFNA2	ephrin-A2	0.012
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.012
TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.012
FGFR4	fibroblast growth factor receptor 4	0.012
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.012
STK36	serine/threonine kinase 36	0.012
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.012
OLIG2	oligodendrocyte lineage transcription factor 2	0.012
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.012
SHH	sonic hedgehog	0.012
SIX3	SIX homeobox 3	0.012
C5orf38	chromosome 5 open reading frame 38	0.012
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.012
RAX	retina and anterior neural fold homeobox	0.012
NPAS1	neuronal PAS domain protein 1	0.011
GATA6	GATA binding protein 6	0.011
BNC1	basonuclin 1	0.011
WT1	Wilms tumor 1	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.011
KCNJ5	potassium inwardly-rectifying channel, subfamily J, member 5	0.011
GLI3	GLI family zinc finger 3	0.011	Mouse
GLI1	GLI family zinc finger 1	0.011
MAX	MYC associated factor X	0.011
EP300	E1A binding protein p300	0.011
SIX6	SIX homeobox 6	0.011
CDH16	cadherin 16, KSP-cadherin	0.011
BTRC	beta-transducin repeat containing	0.011
BCL2L2	BCL2-like 2	0.011
NKD1	naked cuticle homolog 1 (Drosophila)	0.011
IER2	immediate early response 2	0.011
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.011
UTF1	undifferentiated embryonic cell transcription factor 1	0.011
MEOX2	mesenchyme homeobox 2	0.011
HOXB8	homeobox B8	0.010
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.010
HMX3	H6 family homeobox 3	0.010
PTHLH	parathyroid hormone-like hormone	0.010
NKX6-2	NK6 homeobox 2	0.010
JAG1	jagged 1	0.010
LAMC3	laminin, gamma 3	0.010
JAG2	jagged 2	0.010
FOXL1	forkhead box L1	0.010
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.010
ONECUT2	one cut homeobox 2	0.010
NOTCH3	notch 3	0.010
TBX3	T-box 3	0.010
BAD	BCL2-associated agonist of cell death	0.010
OVOL1	ovo-like 1(Drosophila)	0.010
CSF1	colony stimulating factor 1 (macrophage)	0.010