IMP
Process View
regulation of production of molecular mediator of immune response
Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.913 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.905 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.830 | ||
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.824 | ||
| IL4R | interleukin 4 receptor | 0.759 | Mouse | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.723 | Fly | |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.696 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.569 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.531 | ||
| CCR5 | chemokine (C-C motif) receptor 5 | 0.489 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.446 | Fly | |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.440 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.436 | Fly | |
| TRAF1 | TNF receptor-associated factor 1 | 0.429 | Human | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.338 | ||
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.317 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.316 | Human | |
| TRAF2 | TNF receptor-associated factor 2 | 0.293 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.282 | Mouse Rat | |
| GRAP2 | GRB2-related adaptor protein 2 | 0.244 | ||
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | 0.236 | ||
| SOX10 | SRY (sex determining region Y)-box 10 | 0.204 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.195 | Fly | |
| NCOR2 | nuclear receptor corepressor 2 | 0.195 | ||
| PAX3 | paired box 3 | 0.179 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.179 | Fly | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.175 | Fly | |
| IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.165 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.159 | ||
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.158 | ||
| TTR | transthyretin | 0.150 | ||
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.138 | Mouse | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.129 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.124 | ||
| TRADD | TNFRSF1A-associated via death domain | 0.122 | ||
| TICAM2 | toll-like receptor adaptor molecule 2 | 0.119 | ||
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.118 | ||
| CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.113 | Fly | |
| TRAF3 | TNF receptor-associated factor 3 | 0.106 | Human | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.105 | Human | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.101 | Human | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.100 | Fly | |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.098 | ||
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.091 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.091 | Human | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.088 | ||
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.088 | Human | |
| TEK | TEK tyrosine kinase, endothelial | 0.088 | Mouse | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.087 | ||
| TYMP | thymidine phosphorylase | 0.083 | ||
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.082 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.079 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.077 | ||
| A2M | alpha-2-macroglobulin | 0.077 | ||
| RXRA | retinoid X receptor, alpha | 0.075 | ||
| APOC1 | apolipoprotein C-I | 0.073 | ||
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.069 | Human | |
| RBBP4 | retinoblastoma binding protein 4 | 0.065 | ||
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.065 | ||
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.063 | ||
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.061 | ||
| IL4 | interleukin 4 | 0.059 | Mouse | |
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.058 | ||
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.056 | Human | |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.056 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.055 | ||
| IL22RA1 | interleukin 22 receptor, alpha 1 | 0.055 | ||
| ALB | albumin | 0.054 | ||
| SQSTM1 | sequestosome 1 | 0.049 | ||
| CCL8 | chemokine (C-C motif) ligand 8 | 0.048 | Human | |
| HDAC9 | histone deacetylase 9 | 0.047 | ||
| RARA | retinoic acid receptor, alpha | 0.046 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.044 | ||
| TLR2 | toll-like receptor 2 | 0.043 | ||
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.041 | Human | |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.038 | ||
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.038 | ||
| ATG3 | ATG3 autophagy related 3 homolog (S. cerevisiae) | 0.037 | ||
| CD33 | CD33 molecule | 0.037 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.037 | ||
| HP | haptoglobin | 0.037 | ||
| HK3 | hexokinase 3 (white cell) | 0.036 | ||
| PML | promyelocytic leukemia | 0.036 | ||
| IL22RA2 | interleukin 22 receptor, alpha 2 | 0.035 | ||
| IFNG | interferon, gamma | 0.034 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.034 | Human | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.034 | ||
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.034 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.033 | ||
| CD22 | CD22 molecule | 0.033 | ||
| CARD11 | caspase recruitment domain family, member 11 | 0.033 | ||
| ZNF282 | zinc finger protein 282 | 0.032 | ||
| ZNF830 | zinc finger protein 830 | 0.032 | ||
| LY96 | lymphocyte antigen 96 | 0.032 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.032 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.032 | ||
| ANGPT1 | angiopoietin 1 | 0.031 | Mouse | |
| CD48 | CD48 molecule | 0.030 | ||
| CD86 | CD86 molecule | 0.030 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.030 | ||
| PLEK | pleckstrin | 0.029 | ||
| C1QA | complement component 1, q subcomponent, A chain | 0.028 | ||
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.027 | ||
| SLAMF1 | signaling lymphocytic activation molecule family member 1 | 0.027 | ||
| NLRC4 | NLR family, CARD domain containing 4 | 0.026 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.025 | Human | |
| CD80 | CD80 molecule | 0.025 | ||
| IL3 | interleukin 3 (colony-stimulating factor, multiple) | 0.024 | ||
| IL7R | interleukin 7 receptor | 0.024 | ||
| IGSF6 | immunoglobulin superfamily, member 6 | 0.024 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.024 | ||
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.022 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.022 | Fly | |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.021 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.021 | ||
| CCL19 | chemokine (C-C motif) ligand 19 | 0.021 | Human | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.020 | ||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.020 | ||
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.020 | ||
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.020 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.020 | ||
| NLRP3 | NLR family, pyrin domain containing 3 | 0.020 | ||
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.020 | Human | |
| TCF4 | transcription factor 4 | 0.020 | ||
| FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 | 0.020 | ||
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.019 | ||
| SLC15A3 | solute carrier family 15, member 3 | 0.019 | ||
| IRF4 | interferon regulatory factor 4 | 0.018 | ||
| HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 | 0.018 | ||
| AES | amino-terminal enhancer of split | 0.018 | ||
| MARCO | macrophage receptor with collagenous structure | 0.018 | ||
| PTAFR | platelet-activating factor receptor | 0.018 | ||
| APOA1 | apolipoprotein A-I | 0.017 | ||
| SMC1A | structural maintenance of chromosomes 1A | 0.017 | ||
| APOC2 | apolipoprotein C-II | 0.017 | ||
| IL1B | interleukin 1, beta | 0.017 | ||
| TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.017 | ||
| ANGPT2 | angiopoietin 2 | 0.017 | ||
| CMKLR1 | chemokine-like receptor 1 | 0.017 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.017 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.017 | Human | |
| C2 | complement component 2 | 0.017 | ||
| CSF1 | colony stimulating factor 1 (macrophage) | 0.017 | ||
| AIF1 | allograft inflammatory factor 1 | 0.016 | ||
| CCR3 | chemokine (C-C motif) receptor 3 | 0.016 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.016 | ||
| FPR3 | formyl peptide receptor 3 | 0.016 | ||
| IRF5 | interferon regulatory factor 5 | 0.016 | ||
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.015 | ||
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.015 | Fly | |
| SMAD3 | SMAD family member 3 | 0.015 | ||
| BATF | basic leucine zipper transcription factor, ATF-like | 0.015 | ||
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.015 | ||
| TNF | tumor necrosis factor | 0.015 | ||
| IL6R | interleukin 6 receptor | 0.015 | ||
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | 0.015 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.015 | Human | |
| LRDD | leucine-rich repeats and death domain containing | 0.015 | ||
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.015 | ||
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.015 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.015 | ||
| TBX5 | T-box 5 | 0.014 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.014 | ||
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.014 | ||
| C1QB | complement component 1, q subcomponent, B chain | 0.014 | ||
| NRP1 | neuropilin 1 | 0.014 | ||
| THOC5 | THO complex 5 | 0.014 | ||
| NUMBL | numb homolog (Drosophila)-like | 0.014 | ||
| CD163 | CD163 molecule | 0.014 | ||
| BCL2A1 | BCL2-related protein A1 | 0.014 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.013 | ||
| EBI3 | Epstein-Barr virus induced 3 | 0.013 | ||
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 0.013 | ||
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.013 | Human | |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.013 | ||
| PCDH9 | protocadherin 9 | 0.013 | ||
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.013 | Human | |
| KIR3DL2 | killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 | 0.012 | ||
| EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.012 | ||
| SPRR2D | small proline-rich protein 2D | 0.012 | ||
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.012 | ||
| IFNB1 | interferon, beta 1, fibroblast | 0.012 | ||
| TGFB3 | transforming growth factor, beta 3 | 0.012 | ||
| AQP9 | aquaporin 9 | 0.012 | ||
| LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.012 | Human | |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.012 | ||
| EPOR | erythropoietin receptor | 0.012 | ||
| MED12 | mediator complex subunit 12 | 0.012 | ||
| CA12 | carbonic anhydrase XII | 0.012 | ||
| MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.012 | ||
| CARD16 | caspase recruitment domain family, member 16 | 0.012 | ||
| TGFB1 | transforming growth factor, beta 1 | 0.012 | ||
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.012 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.012 | ||
| LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.012 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.012 | ||
| C3AR1 | complement component 3a receptor 1 | 0.012 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.012 | Fly | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.011 | ||
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.011 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.011 | ||
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) | 0.011 | ||
| VCAM1 | vascular cell adhesion molecule 1 | 0.011 | ||
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | 0.011 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.011 | ||
| CASP5 | caspase 5, apoptosis-related cysteine peptidase | 0.011 | Fly | |
| TLR7 | toll-like receptor 7 | 0.011 | ||
| SIRPB1 | signal-regulatory protein beta 1 | 0.011 | ||
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.011 | ||
| CD209 | CD209 molecule | 0.011 | ||
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | 0.011 | ||
| CCL23 | chemokine (C-C motif) ligand 23 | 0.011 | Human | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.011 | ||
| INADL | InaD-like (Drosophila) | 0.011 | ||
| TLR1 | toll-like receptor 1 | 0.011 | ||
| PYCARD | PYD and CARD domain containing | 0.010 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.010 | ||
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.010 | ||
| CD72 | CD72 molecule | 0.010 | ||
| SIGLEC9 | sialic acid binding Ig-like lectin 9 | 0.010 | ||
| APOC3 | apolipoprotein C-III | 0.010 | ||
| CTBP2 | C-terminal binding protein 2 | 0.010 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.010 | ||
| CHIT1 | chitinase 1 (chitotriosidase) | 0.010 | ||
| FGL2 | fibrinogen-like 2 | 0.010 | ||
| IL10 | interleukin 10 | 0.010 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.010 |