IMP

Process View

Homo sapiens

20 genes annotated in human

response to monosaccharide

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to monosaccharide"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to monosaccharide" (in gray)

Name	Description	Probability	Func Analog Organism
HNF4A	hepatocyte nuclear factor 4, alpha	0.597	Mouse Rat
SMAD3	SMAD family member 3	0.510
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.394	Rat
IL1R1	interleukin 1 receptor, type I	0.305	Rat
FN1	fibronectin 1	0.301	Rat
SMAD2	SMAD family member 2	0.300	Mouse
SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14	0.246	Rat
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.211
CCNY	cyclin Y	0.205
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.170
NCF1	neutrophil cytosolic factor 1	0.164
PLAUR	plasminogen activator, urokinase receptor	0.158
VIM	vimentin	0.153
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.149
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.143
PTEN	phosphatase and tensin homolog	0.135	Rat
PLAU	plasminogen activator, urokinase	0.134	Rat
FYN	FYN oncogene related to SRC, FGR, YES	0.130
NOSTRIN	nitric oxide synthase trafficker	0.125
SNAP23	synaptosomal-associated protein, 23kDa	0.124
CREBBP	CREB binding protein	0.114
IL8	interleukin 8	0.105
SNAP25	synaptosomal-associated protein, 25kDa	0.100
BCAR1	breast cancer anti-estrogen resistance 1	0.087
NCF4	neutrophil cytosolic factor 4, 40kDa	0.087
SREBF2	sterol regulatory element binding transcription factor 2	0.085
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.084
HIPK2	homeodomain interacting protein kinase 2	0.079
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.079
BCL2L1	BCL2-like 1	0.078
IL1B	interleukin 1, beta	0.078	Rat
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.077
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.067
ONECUT1	one cut homeobox 1	0.060
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.058
SNAI1	snail homolog 1 (Drosophila)	0.055
S100B	S100 calcium binding protein B	0.055
ESR1	estrogen receptor 1	0.055
INSR	insulin receptor	0.055	Rat
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.055
FASLG	Fas ligand (TNF superfamily, member 6)	0.054
BBS1	Bardet-Biedl syndrome 1	0.054
IL1RAP	interleukin 1 receptor accessory protein	0.054
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.053	Rat
GRB10	growth factor receptor-bound protein 10	0.052
APAF1	apoptotic peptidase activating factor 1	0.052
AGXT2	alanine--glyoxylate aminotransferase 2	0.051
HNF1A	HNF1 homeobox A	0.050	Mouse
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.047
TGFBR1	transforming growth factor, beta receptor 1	0.046
TGFB3	transforming growth factor, beta 3	0.046
VEGFA	vascular endothelial growth factor A	0.046
ADAM15	ADAM metallopeptidase domain 15	0.045
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.044
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.044
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.044
COL3A1	collagen, type III, alpha 1	0.044
RNASE4	ribonuclease, RNase A family, 4	0.044
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.043
MYOD1	myogenic differentiation 1	0.042
PRKCA	protein kinase C, alpha	0.041
IQGAP1	IQ motif containing GTPase activating protein 1	0.041
PDX1	pancreatic and duodenal homeobox 1	0.041	Mouse
IGF1R	insulin-like growth factor 1 receptor	0.040
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.040
EIF2B4	eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa	0.040
SPTBN4	spectrin, beta, non-erythrocytic 4	0.039
ULK1	unc-51-like kinase 1 (C. elegans)	0.038
RANBP9	RAN binding protein 9	0.038
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.038
CRHR1	corticotropin releasing hormone receptor 1	0.038
DAXX	death-domain associated protein	0.037
FSTL1	follistatin-like 1	0.037
CAV1	caveolin 1, caveolae protein, 22kDa	0.037
MSN	moesin	0.037
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.037
GATA2	GATA binding protein 2	0.035
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.035
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.033
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.033
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.033
INCENP	inner centromere protein antigens 135/155kDa	0.032
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.032
UBQLN1	ubiquilin 1	0.032
PLAT	plasminogen activator, tissue	0.031
PROX1	prospero homeobox 1	0.031
CYR61	cysteine-rich, angiogenic inducer, 61	0.030
SETD8	SET domain containing (lysine methyltransferase) 8	0.030
MAPT	microtubule-associated protein tau	0.028
PSEN2	presenilin 2 (Alzheimer disease 4)	0.028
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.028
TCF12	transcription factor 12	0.028
IRF2	interferon regulatory factor 2	0.027
PRDX1	peroxiredoxin 1	0.027
TP53	tumor protein p53	0.026
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.026
SOCS3	suppressor of cytokine signaling 3	0.026
HNF1B	HNF1 homeobox B	0.025	Mouse
STX5	syntaxin 5	0.025
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.025
MKL1	megakaryoblastic leukemia (translocation) 1	0.025
KAT2B	K(lysine) acetyltransferase 2B	0.025
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.025
AMBP	alpha-1-microglobulin/bikunin precursor	0.025
BHLHE40	basic helix-loop-helix family, member e40	0.024
CDCP1	CUB domain containing protein 1	0.024
EMP1	epithelial membrane protein 1	0.024
CD44	CD44 molecule (Indian blood group)	0.024
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.024
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.024
IRS1	insulin receptor substrate 1	0.023
CXCL3	chemokine (C-X-C motif) ligand 3	0.023
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.023
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.023
SRGN	serglycin	0.023
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.022	Rat
NME1	non-metastatic cells 1, protein (NM23A) expressed in	0.022
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.022
FBLN2	fibulin 2	0.021
PML	promyelocytic leukemia	0.021
COASY	CoA synthase	0.021
IL1RN	interleukin 1 receptor antagonist	0.020
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.020
CDX2	caudal type homeobox 2	0.019
C16orf75	chromosome 16 open reading frame 75	0.019
ENG	endoglin	0.019
NME2	non-metastatic cells 2, protein (NM23B) expressed in	0.019	Rat
GJA1	gap junction protein, alpha 1, 43kDa	0.019
ACTB	actin, beta	0.019
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.018
RPL8	ribosomal protein L8	0.018
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.018
BGN	biglycan	0.018
NME3	non-metastatic cells 3, protein expressed in	0.018
YY1	YY1 transcription factor	0.017
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.017
AKIP1	A kinase (PRKA) interacting protein 1	0.017
APP	amyloid beta (A4) precursor protein	0.017
PECAM1	platelet/endothelial cell adhesion molecule	0.017
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.017
MAPK6	mitogen-activated protein kinase 6	0.017
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.017
XIAP	X-linked inhibitor of apoptosis	0.017
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.016
MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	0.016
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.016
ALB	albumin	0.016
PSEN1	presenilin 1	0.016
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.016
MUC1	mucin 1, cell surface associated	0.016
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.016
ESRRG	estrogen-related receptor gamma	0.016
CSNK1A1	casein kinase 1, alpha 1	0.016
PPP4R2	protein phosphatase 4, regulatory subunit 2	0.016
PAX2	paired box 2	0.016	Mouse
EP300	E1A binding protein p300	0.015
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.015
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.015
MED15	mediator complex subunit 15	0.015
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.015
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.015
CCL2	chemokine (C-C motif) ligand 2	0.015
TIMP1	TIMP metallopeptidase inhibitor 1	0.015
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.014
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.014	Rat
HOXD12	homeobox D12	0.014
PDCD6IP	programmed cell death 6 interacting protein	0.014
IL6	interleukin 6 (interferon, beta 2)	0.014
POU4F2	POU class 4 homeobox 2	0.014
NNMT	nicotinamide N-methyltransferase	0.014
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.014
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.014
NKX6-1	NK6 homeobox 1	0.014
TJP2	tight junction protein 2 (zona occludens 2)	0.014
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.014
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.014
CCND3	cyclin D3	0.014
VCAN	versican	0.014
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.013
FEV	FEV (ETS oncogene family)	0.013
PIM1	pim-1 oncogene	0.013
BAI1	brain-specific angiogenesis inhibitor 1	0.013
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.013
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.013
HLA-DMB	major histocompatibility complex, class II, DM beta	0.013
SFTPC	surfactant protein C	0.013
GABARAPL1	GABA(A) receptor-associated protein like 1	0.013
HDAC1	histone deacetylase 1	0.013
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.013
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.013
FGF3	fibroblast growth factor 3	0.013
GATA4	GATA binding protein 4	0.013	Rat
SPHK1	sphingosine kinase 1	0.013
MYO16	myosin XVI	0.012
MYOCD	myocardin	0.012
BAIAP2	BAI1-associated protein 2	0.012
IRS2	insulin receptor substrate 2	0.012	Mouse
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.012
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.012
NME4	non-metastatic cells 4, protein expressed in	0.012
THBS1	thrombospondin 1	0.012
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.012
EZR	ezrin	0.012
RYR2	ryanodine receptor 2 (cardiac)	0.012
SLC38A2	solute carrier family 38, member 2	0.012
HDAC3	histone deacetylase 3	0.012
PITPNM1	phosphatidylinositol transfer protein, membrane-associated 1	0.012
OSMR	oncostatin M receptor	0.012
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.012	Rat
HMG20B	high mobility group 20B	0.012
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.012
CHRNB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	0.012
CYBA	cytochrome b-245, alpha polypeptide	0.011
NEUROD1	neurogenic differentiation 1	0.011
ND5	NADH dehydrogenase, subunit 5 (complex I)	0.011
DLGAP2	discs, large (Drosophila) homolog-associated protein 2	0.011
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.011
KEAP1	kelch-like ECH-associated protein 1	0.011
PRKCB	protein kinase C, beta	0.011
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.011
TALDO1	transaldolase 1	0.011
HAND2	heart and neural crest derivatives expressed 2	0.011	Human
GAD2	glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)	0.011
EGR3	early growth response 3	0.011
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.011
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.011
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.011
RUNX1	runt-related transcription factor 1	0.011
ANXA1	annexin A1	0.011
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.011
SOD2	superoxide dismutase 2, mitochondrial	0.011
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.011	Human
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.011
PARK7	Parkinson disease (autosomal recessive, early onset) 7	0.011
SRCIN1	SRC kinase signaling inhibitor 1	0.011
SH2B1	SH2B adaptor protein 1	0.010
PRKCD	protein kinase C, delta	0.010	Rat
PAH	phenylalanine hydroxylase	0.010
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.010
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.010
BCL3	B-cell CLL/lymphoma 3	0.010
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.010
SETD7	SET domain containing (lysine methyltransferase) 7	0.010
LTBP4	latent transforming growth factor beta binding protein 4	0.010
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.010
ANXA2	annexin A2	0.010
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.010
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.010