IMP

Process View

Mus musculus

17 genes annotated in mouse

regulation of muscle cell apoptotic process

Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of muscle cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of muscle cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.892
Hand2	heart and neural crest derivatives expressed transcript 2	0.884
Hand1	heart and neural crest derivatives expressed transcript 1	0.841	Mouse
Neurod1	neurogenic differentiation 1	0.811	Mouse
Shh	sonic hedgehog	0.789
Ptf1a	pancreas specific transcription factor, 1a	0.778	Mouse
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.724
Pten	phosphatase and tensin homolog	0.672
Emx1	empty spiracles homolog 1 (Drosophila)	0.634
Isl1	ISL1 transcription factor, LIM/homeodomain	0.608
Ddx60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.556
Mdm2	transformed mouse 3T3 cell double minute 2	0.446
Otx2	orthodenticle homolog 2 (Drosophila)	0.437
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.433
Gata4	GATA binding protein 4	0.395
Trp53	transformation related protein 53	0.364
Neurog2	neurogenin 2	0.353	Mouse
Pax6	paired box gene 6	0.335
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.331
Tbx5	T-box 5	0.326
Tgfbr2	transforming growth factor, beta receptor II	0.306
Insm1	insulinoma-associated 1	0.261
Pthlh	parathyroid hormone-like peptide	0.257
Mecom	MDS1 and EVI1 complex locus	0.256
Ntf3	neurotrophin 3	0.251
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.249
Hoxd13	homeobox D13	0.246
Hoxa1	homeobox A1	0.241
Sox9	SRY-box containing gene 9	0.224
Kiss1	KiSS-1 metastasis-suppressor	0.214
Sfrp2	secreted frizzled-related protein 2	0.188
Apc	adenomatosis polyposis coli	0.185
Prph2	peripherin 2	0.173
Fgf8	fibroblast growth factor 8	0.165
Sfrp1	secreted frizzled-related protein 1	0.164	Mouse
Gli2	GLI-Kruppel family member GLI2	0.161
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.155
Col1a1	collagen, type I, alpha 1	0.152
Pdx1	pancreatic and duodenal homeobox 1	0.147
Grb10	growth factor receptor bound protein 10	0.133
Nf1	neurofibromatosis 1	0.130
Gata1	GATA binding protein 1	0.119
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.116
Nos3	nitric oxide synthase 3, endothelial cell	0.114
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.112
Foxc2	forkhead box C2	0.110
Rxra	retinoid X receptor alpha	0.104
Ep300	E1A binding protein p300	0.102
Lepr	leptin receptor	0.100
T	brachyury	0.099
Nkx6-1	NK6 homeobox 1	0.092
Socs1	suppressor of cytokine signaling 1	0.091
Gp9	glycoprotein 9 (platelet)	0.090
Pax3	paired box gene 3	0.086
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.085
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.083
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.083
Sox11	SRY-box containing gene 11	0.082
Rb1	retinoblastoma 1	0.077
Tgfb2	transforming growth factor, beta 2	0.076
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.074
Igf2	insulin-like growth factor 2	0.073
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.072
Gsk3b	glycogen synthase kinase 3 beta	0.067
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.065
Neurog3	neurogenin 3	0.060	Mouse
Fbn1	fibrillin 1	0.058
Lep	leptin	0.055
Npc1	Niemann Pick type C1	0.054
Mdm4	transformed mouse 3T3 cell double minute 4	0.054
Trp63	transformation related protein 63	0.053	Mouse
Alx3	aristaless-like homeobox 3	0.053
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.052
Msx1	homeobox, msh-like 1	0.051
Meox2	mesenchyme homeobox 2	0.050
Tbx1	T-box 1	0.049
Phox2b	paired-like homeobox 2b	0.048
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.047
Hes5	hairy and enhancer of split 5 (Drosophila)	0.047
Cdh23	cadherin 23 (otocadherin)	0.046
Mesp1	mesoderm posterior 1	0.046
Wnt6	wingless-related MMTV integration site 6	0.046
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.045
Utf1	undifferentiated embryonic cell transcription factor 1	0.045
Nhlh1	nescient helix loop helix 1	0.045	Mouse
Smn1	survival motor neuron 1	0.044
Arx	aristaless related homeobox	0.044
Esx1	extraembryonic, spermatogenesis, homeobox 1	0.044
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.043
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.042
Onecut1	one cut domain, family member 1	0.042
Pax9	paired box gene 9	0.042
Gata6	GATA binding protein 6	0.041
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.041
Rpl4	ribosomal protein L4	0.040
Mdfi	MyoD family inhibitor	0.040
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.040
Adam17	a disintegrin and metallopeptidase domain 17	0.039
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.039
En1	engrailed 1	0.038
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.038
Ebf2	early B-cell factor 2	0.037
Tal2	T-cell acute lymphocytic leukemia 2	0.036	Mouse
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.036
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.035
Foxe1	forkhead box E1	0.035
Mobp	myelin-associated oligodendrocytic basic protein	0.034
Gja1	gap junction protein, alpha 1	0.034
Tcfap2a	transcription factor AP-2, alpha	0.034
Pou2f2	POU domain, class 2, transcription factor 2	0.034
Neurod4	neurogenic differentiation 4	0.034	Mouse
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.033
Usp18	ubiquitin specific peptidase 18	0.033
Twist1	twist homolog 1 (Drosophila)	0.033	Mouse
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.033
Pou3f2	POU domain, class 3, transcription factor 2	0.033
Fgf15	fibroblast growth factor 15	0.032
Meox1	mesenchyme homeobox 1	0.032
Foxc1	forkhead box C1	0.032
Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	0.032
Epor	erythropoietin receptor	0.032
Atoh7	atonal homolog 7 (Drosophila)	0.031	Mouse
Prrx2	paired related homeobox 2	0.031
Lhx5	LIM homeobox protein 5	0.031
Tlx3	T-cell leukemia, homeobox 3	0.030
Thbs1	thrombospondin 1	0.030
Sox1	SRY-box containing gene 1	0.030
Actn2	actinin alpha 2	0.029
Sct	secretin	0.029
Nrk	Nik related kinase	0.029
Hes2	hairy and enhancer of split 2 (Drosophila)	0.029
Kcnj11	potassium inwardly rectifying channel, subfamily J, member 11	0.029
Mtap2	microtubule-associated protein 2	0.029
Otp	orthopedia homolog (Drosophila)	0.029
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.029
Pitx1	paired-like homeodomain transcription factor 1	0.028
Crebbp	CREB binding protein	0.028
Clock	circadian locomotor output cycles kaput	0.028
Cdx2	caudal type homeobox 2	0.028
Ctnnb1	catenin (cadherin associated protein), beta 1	0.027
Col22a1	collagen, type XXII, alpha 1	0.027
Shox2	short stature homeobox 2	0.027
Trim25	tripartite motif-containing 25	0.026
Agtrap	angiotensin II, type I receptor-associated protein	0.026
Barx1	BarH-like homeobox 1	0.026
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.026
Trp73	transformation related protein 73	0.026	Mouse
Elf1	E74-like factor 1	0.026
Epha3	Eph receptor A3	0.026
Olfr70	olfactory receptor 70	0.026
Smad4	MAD homolog 4 (Drosophila)	0.025
Ren1	renin 1 structural	0.025
Tbx20	T-box 20	0.025
Fbn2	fibrillin 2	0.025
Hoxa13	homeobox A13	0.024
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.024
Hoxd12	homeobox D12	0.024
Wnt5a	wingless-related MMTV integration site 5A	0.024
Lmo2	LIM domain only 2	0.024
Myt1	myelin transcription factor 1	0.024
Rtp4	receptor transporter protein 4	0.023
Nog	noggin	0.023
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.023
Snai1	snail homolog 1 (Drosophila)	0.023
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.023
Gja5	gap junction protein, alpha 5	0.023
Runx2	runt related transcription factor 2	0.023
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.022
Isl2	insulin related protein 2 (islet 2)	0.022
Cacng2	calcium channel, voltage-dependent, gamma subunit 2	0.022
Vax1	ventral anterior homeobox containing gene 1	0.022
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.022
Ebf3	early B-cell factor 3	0.022
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.021
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.021
Stat1	signal transducer and activator of transcription 1	0.021
Flii	flightless I homolog (Drosophila)	0.021
Mnx1	motor neuron and pancreas homeobox 1	0.021
Skil	SKI-like	0.020
Bdkrb2	bradykinin receptor, beta 2	0.020	Mouse
Dcc	deleted in colorectal carcinoma	0.020
Samd9l	sterile alpha motif domain containing 9-like	0.020
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.020
Obsl1	obscurin-like 1	0.020
Omp	olfactory marker protein	0.020
Gfi1b	growth factor independent 1B	0.019
Sfrp5	secreted frizzled-related sequence protein 5	0.019	Mouse
Adra2b	adrenergic receptor, alpha 2b	0.019
Ednra	endothelin receptor type A	0.019
Mab21l2	mab-21-like 2 (C. elegans)	0.019
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.019
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.019
Pou4f2	POU domain, class 4, transcription factor 2	0.019
Insr	insulin receptor	0.019
Prox1	prospero-related homeobox 1	0.019
Igf2r	insulin-like growth factor 2 receptor	0.019
Tbx3	T-box 3	0.018
Btbd17	BTB (POZ) domain containing 17	0.018
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.018
Gpr50	G-protein-coupled receptor 50	0.018
Gbp7	guanylate binding protein 7	0.018
Vegfa	vascular endothelial growth factor A	0.018
Tcf15	transcription factor 15	0.018	Mouse
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.018
Uox	urate oxidase	0.018
Hhat	hedgehog acyltransferase	0.018
Oas3	2'-5' oligoadenylate synthetase 3	0.018
Atr	ataxia telangiectasia and Rad3 related	0.018
Fgf16	fibroblast growth factor 16	0.017
Foxf1a	forkhead box F1a	0.017
Fgfr2	fibroblast growth factor receptor 2	0.017
Bdnf	brain derived neurotrophic factor	0.017
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.017
Glis3	GLIS family zinc finger 3	0.017
1700065I17Rik	RIKEN cDNA 1700065I17 gene	0.017
Grm1	glutamate receptor, metabotropic 1	0.017
Whrn	whirlin	0.017
Hoxd3	homeobox D3	0.017
Nhlh2	nescient helix loop helix 2	0.017	Mouse
Hic1	hypermethylated in cancer 1	0.017
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.017
Lhx6	LIM homeobox protein 6	0.017
Col2a1	collagen, type II, alpha 1	0.017
Fgf17	fibroblast growth factor 17	0.017
Nppc	natriuretic peptide type C	0.017
Evx2	even skipped homeotic gene 2 homolog	0.016
Gip	gastric inhibitory polypeptide	0.016
Igfbpl1	insulin-like growth factor binding protein-like 1	0.016
Cxcr4	chemokine (C-X-C motif) receptor 4	0.016
Nxph4	neurexophilin 4	0.016
Foxd4	forkhead box D4	0.016
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.016
Pcdh12	protocadherin 12	0.016
Aicda	activation-induced cytidine deaminase	0.016
Csf1	colony stimulating factor 1 (macrophage)	0.016
Zeb1	zinc finger E-box binding homeobox 1	0.016
Foxg1	forkhead box G1	0.016
Tcf21	transcription factor 21	0.016
Tas1r1	taste receptor, type 1, member 1	0.016
Dlk1	delta-like 1 homolog (Drosophila)	0.016
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.016
Foxa2	forkhead box A2	0.015
Lhx3	LIM homeobox protein 3	0.015
Col11a2	collagen, type XI, alpha 2	0.015
Fndc7	fibronectin type III domain containing 7	0.015
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.015
Ggt5	gamma-glutamyltransferase 5	0.015
Ghr	growth hormone receptor	0.015
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.015
Akap9	A kinase (PRKA) anchor protein (yotiao) 9	0.015
Parp14	poly (ADP-ribose) polymerase family, member 14	0.015
Hes3	hairy and enhancer of split 3 (Drosophila)	0.015
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.015
Col15a1	collagen, type XV, alpha 1	0.015
Psen1	presenilin 1	0.015
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.015
Srrm4	serine/arginine repetitive matrix 4	0.014
Dscam	Down syndrome cell adhesion molecule	0.014
Klk1b11	kallikrein 1-related peptidase b11	0.014
Nbn	nibrin	0.014
Atoh1	atonal homolog 1 (Drosophila)	0.014	Mouse
Ctsg	cathepsin G	0.014
Akp3	alkaline phosphatase 3, intestine, not Mn requiring	0.014
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.014
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.014
Cbl	Casitas B-lineage lymphoma	0.014
Masp1	mannan-binding lectin serine peptidase 1	0.014
Efs	embryonal Fyn-associated substrate	0.014
Igf1	insulin-like growth factor 1	0.014	Human
Zic1	zinc finger protein of the cerebellum 1	0.014
Neurl1a	neuralized homolog 1A (Drosophila)	0.014
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.014
Amhr2	anti-Mullerian hormone type 2 receptor	0.014
Lox	lysyl oxidase	0.014
Chrnb4	cholinergic receptor, nicotinic, beta polypeptide 4	0.014
Zfhx4	zinc finger homeodomain 4	0.014
Zfpm2	zinc finger protein, multitype 2	0.014
Prrx1	paired related homeobox 1	0.014
Ltbp1	latent transforming growth factor beta binding protein 1	0.014
Sox2	SRY-box containing gene 2	0.013
Has2	hyaluronan synthase 2	0.013
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.013
Mybpc3	myosin binding protein C, cardiac	0.013
Crtc3	CREB regulated transcription coactivator 3	0.013
Parp12	poly (ADP-ribose) polymerase family, member 12	0.013
Glra1	glycine receptor, alpha 1 subunit	0.013
Hoxd1	homeobox D1	0.013
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.013
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.013
Yap1	yes-associated protein 1	0.013
Ccnd1	cyclin D1	0.013
Dtx1	deltex 1 homolog (Drosophila)	0.013
Huwe1	HECT, UBA and WWE domain containing 1	0.012
Dsc3	desmocollin 3	0.012
Tbx19	T-box 19	0.012
Gdnf	glial cell line derived neurotrophic factor	0.012
Dnm1	dynamin 1	0.012
Irx4	Iroquois related homeobox 4 (Drosophila)	0.012
Gipc3	GIPC PDZ domain containing family, member 3	0.012
Fgf5	fibroblast growth factor 5	0.012
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.012
Nobox	NOBOX oogenesis homeobox	0.012
Myh10	myosin, heavy polypeptide 10, non-muscle	0.012
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.012
Oasl2	2'-5' oligoadenylate synthetase-like 2	0.012
Prl	prolactin	0.012
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.012
Hcrt	hypocretin	0.012
Tal1	T-cell acute lymphocytic leukemia 1	0.012	Mouse
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.012
Wt1	Wilms tumor 1 homolog	0.012
Egfr	epidermal growth factor receptor	0.012
Krt14	keratin 14	0.012
Fyn	Fyn proto-oncogene	0.012
Pnliprp2	pancreatic lipase-related protein 2	0.012
Rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.011
Acvr1	activin A receptor, type 1	0.011
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.011
Pitx3	paired-like homeodomain transcription factor 3	0.011
E2f1	E2F transcription factor 1	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Hoxc9	homeobox C9	0.011
BC057022	cDNA sequence BC057022	0.011
Stk32b	serine/threonine kinase 32B	0.011
Gucy2e	guanylate cyclase 2e	0.011
Runx1	runt related transcription factor 1	0.011
Ascl2	achaete-scute complex homolog 2 (Drosophila)	0.011
Fam20c	family with sequence similarity 20, member C	0.011
Slc4a8	solute carrier family 4 (anion exchanger), member 8	0.011
Asb12	ankyrin repeat and SOCS box-containing 12	0.011
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.011	Mouse
Insm2	insulinoma-associated 2	0.011
Ldb3	LIM domain binding 3	0.011
Bhlha9	basic helix-loop-helix family, member a9	0.011
Sfn	stratifin	0.011
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.011
Efnb2	ephrin B2	0.011
Hoxc6	homeobox C6	0.011
Arc	activity regulated cytoskeletal-associated protein	0.011
Tcf3	transcription factor 3	0.011
Ptch1	patched homolog 1	0.010
Col8a1	collagen, type VIII, alpha 1	0.010
Nkx2-9	NK2 transcription factor related, locus 9 (Drosophila)	0.010	Mouse
Sav1	salvador homolog 1 (Drosophila)	0.010
Pum1	pumilio 1 (Drosophila)	0.010
Foxp2	forkhead box P2	0.010
Robo3	roundabout homolog 3 (Drosophila)	0.010
Rax	retina and anterior neural fold homeobox	0.010
Tead4	TEA domain family member 4	0.010