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Mus musculus

0 genes annotated in mouse

endocrine gland cancer

DOID:170

An organ system cancer located in endocrine system that is characterized by uncontrolled cellular proliferation of the hormone producing glands of the endocrine system.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endocrine gland cancer" (in gray)

Name	Description	Probability	Func Analog Organism
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	1.000	Human
Trp53	transformation related protein 53	1.000	Human
Brca1	breast cancer 1	0.992	Human
Pten	phosphatase and tensin homolog	0.992	Human
Apc	adenomatosis polyposis coli	0.991
Ctnnb1	catenin (cadherin associated protein), beta 1	0.978
Rb1	retinoblastoma 1	0.951
Mdm2	transformed mouse 3T3 cell double minute 2	0.885
Braf	Braf transforming gene	0.565
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.549
Msh2	mutS homolog 2 (E. coli)	0.528
Raf1	v-raf-leukemia viral oncogene 1	0.446
Nf2	neurofibromatosis 2	0.320
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.291
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.279
Brca2	breast cancer 2	0.275	Human
Atm	ataxia telangiectasia mutated homolog (human)	0.264
Smad4	MAD homolog 4 (Drosophila)	0.204	Human
Vhl	von Hippel-Lindau tumor suppressor	0.200
Cbx5	chromobox homolog 5 (Drosophila HP1a)	0.199
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.195
Atr	ataxia telangiectasia and Rad3 related	0.141
Esr1	estrogen receptor 1 (alpha)	0.132
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.129
Ptch1	patched homolog 1	0.125
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.122
Nf1	neurofibromatosis 1	0.119
Lepr	leptin receptor	0.114
Kif2a	kinesin family member 2A	0.107
Rnf2	ring finger protein 2	0.100
Cep290	centrosomal protein 290	0.095
Fgfr2	fibroblast growth factor receptor 2	0.093
Kit	kit oncogene	0.081
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.079
Zfp830	zinc finger protein 830	0.074
Meox2	mesenchyme homeobox 2	0.072
Cbx1	chromobox homolog 1 (Drosophila HP1 beta)	0.068
Suclg1	succinate-CoA ligase, GDP-forming, alpha subunit	0.067
Col1a1	collagen, type I, alpha 1	0.064
Nbn	nibrin	0.062
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.061
Fas	Fas (TNF receptor superfamily member 6)	0.058
Zmym2	zinc finger, MYM-type 2	0.056
BC018507	cDNA sequence BC018507	0.055
Rxra	retinoid X receptor alpha	0.055
Ylpm1	YLP motif containing 1	0.054
Kitl	kit ligand	0.052
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.051
Sdha	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.051
Hif1a	hypoxia inducible factor 1, alpha subunit	0.050
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.047
Scaf8	SR-related CTD-associated factor 8	0.045
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.042
Ndufa9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9	0.041
Mdm4	transformed mouse 3T3 cell double minute 4	0.041
Stk11	serine/threonine kinase 11	0.039	Human
Smad3	MAD homolog 3 (Drosophila)	0.037
Fbxo11	F-box protein 11	0.036
Sox9	SRY-box containing gene 9	0.033
Uqcrc1	ubiquinol-cytochrome c reductase core protein 1	0.032
Rac1	RAS-related C3 botulinum substrate 1	0.032
Usp9x	ubiquitin specific peptidase 9, X chromosome	0.032
Rint1	RAD50 interactor 1	0.031
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.031
Spnb2	spectrin beta 2	0.030
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.029	Human
Ccnd1	cyclin D1	0.029
Rpgr	retinitis pigmentosa GTPase regulator	0.028
Itga6	integrin alpha 6	0.028
Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.027
Mapk14	mitogen-activated protein kinase 14	0.026
Tsc1	tuberous sclerosis 1	0.026
Smad2	MAD homolog 2 (Drosophila)	0.026
Thbs1	thrombospondin 1	0.025
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.025
Lsm14a	LSM14 homolog A (SCD6, S. cerevisiae)	0.024
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.024
Epc2	enhancer of polycomb homolog 2 (Drosophila)	0.024
Ap2s1	adaptor-related protein complex 2, sigma 1 subunit	0.024
Bmi1	Bmi1 polycomb ring finger oncogene	0.024
Atp5a1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1	0.023
C80913	expressed sequence C80913	0.023
Aes	amino-terminal enhancer of split	0.022
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.022
E2f1	E2F transcription factor 1	0.022
Stat3	signal transducer and activator of transcription 3	0.022
Suz12	suppressor of zeste 12 homolog (Drosophila)	0.022
Lyz2	lysozyme 2	0.021
Qser1	glutamine and serine rich 1	0.021
Mapk8	mitogen-activated protein kinase 8	0.020
Dmtf1	cyclin D binding myb-like transcription factor 1	0.020
Acot7	acyl-CoA thioesterase 7	0.020
Cdkn2c	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.020
Mga	MAX gene associated	0.020
Sav1	salvador homolog 1 (Drosophila)	0.020
Ntf3	neurotrophin 3	0.019
Ptbp2	polypyrimidine tract binding protein 2	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Fancd2	Fanconi anemia, complementation group D2	0.019
Tgfbr1	transforming growth factor, beta receptor I	0.019
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.018
Zfp292	zinc finger protein 292	0.018
Zfp654	zinc finger protein 654	0.018
Cs	citrate synthase	0.018
Atf2	activating transcription factor 2	0.018
Egln3	EGL nine homolog 3 (C. elegans)	0.018
Mbd3	methyl-CpG binding domain protein 3	0.017
Rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.017
Calm2	calmodulin 2	0.017
Trpm7	transient receptor potential cation channel, subfamily M, member 7	0.017
Notch1	Notch gene homolog 1 (Drosophila)	0.017
Matr3	matrin 3	0.017
Lats1	large tumor suppressor	0.017
Otud4	OTU domain containing 4	0.016
Ppp1ca	protein phosphatase 1, catalytic subunit, alpha isoform	0.016
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.016
Tmem14c	transmembrane protein 14C	0.016
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.016
Rfwd2	ring finger and WD repeat domain 2	0.016
Trip12	thyroid hormone receptor interactor 12	0.016
Smad1	MAD homolog 1 (Drosophila)	0.016
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.016
6330503K22Rik	RIKEN cDNA 6330503K22 gene	0.016
Txn2	thioredoxin 2	0.015
Kdm3a	lysine (K)-specific demethylase 3A	0.015
Bcl2	B-cell leukemia/lymphoma 2	0.015
Slc25a11	solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11	0.015
Hspbp1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1	0.015
Csnk2a2	casein kinase 2, alpha prime polypeptide	0.015
Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	0.015
Pde7a	phosphodiesterase 7A	0.015
Lhx1	LIM homeobox protein 1	0.015
Lrrcc1	leucine rich repeat and coiled-coil domain containing 1	0.014
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.014
Mapre1	microtubule-associated protein, RP/EB family, member 1	0.014
Rfx7	regulatory factor X, 7	0.014
Smc6	structural maintenance of chromosomes 6	0.014
Zfp280c	zinc finger protein 280C	0.014
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.013
Zfp26	zinc finger protein 26	0.013
Aco2	aconitase 2, mitochondrial	0.013
Pcgf6	polycomb group ring finger 6	0.013
Rad51	RAD51 homolog (S. cerevisiae)	0.013
Rara	retinoic acid receptor, alpha	0.013
Tgfb2	transforming growth factor, beta 2	0.013
Csnk2b	casein kinase 2, beta polypeptide	0.013
Mphosph9	M-phase phosphoprotein 9	0.013
Pgam1	phosphoglycerate mutase 1	0.013
Trim23	tripartite motif-containing 23	0.013
Snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.013
Zranb1	zinc finger, RAN-binding domain containing 1	0.013
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.013
Kif16b	kinesin family member 16B	0.013
Ndufb6	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6	0.013
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.012
Mib1	mindbomb homolog 1 (Drosophila)	0.012
Ogdh	oxoglutarate dehydrogenase (lipoamide)	0.012
Senp6	SUMO/sentrin specific peptidase 6	0.012
Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	0.012	Human
Zfp451	zinc finger protein 451	0.012
Chuk	conserved helix-loop-helix ubiquitous kinase	0.012
Dync1i2	dynein cytoplasmic 1 intermediate chain 2	0.012
Gsk3b	glycogen synthase kinase 3 beta	0.012
Rnf126	ring finger protein 126	0.012
Pparg	peroxisome proliferator activated receptor gamma	0.012
Kdm1a	lysine (K)-specific demethylase 1A	0.012
Pcm1	pericentriolar material 1	0.012	Human
Zzz3	zinc finger, ZZ domain containing 3	0.012
Apoe	apolipoprotein E	0.012
Gja1	gap junction protein, alpha 1	0.011
Trove2	TROVE domain family, member 2	0.011
Ptk2	PTK2 protein tyrosine kinase 2	0.011
Yap1	yes-associated protein 1	0.011
Parg	poly (ADP-ribose) glycohydrolase	0.011
Obfc2b	oligonucleotide/oligosaccharide-binding fold containing 2B	0.011
Pik3cb	phosphatidylinositol 3-kinase, catalytic, beta polypeptide	0.011
Pds5b	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.011
Uqcrfs1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.011
Npc1	Niemann Pick type C1	0.011
Cul3	cullin 3	0.011
Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.011
Morf4l1	mortality factor 4 like 1	0.011
Impad1	inositol monophosphatase domain containing 1	0.011
Arid4b	AT rich interactive domain 4B (RBP1-like)	0.011
Nos3	nitric oxide synthase 3, endothelial cell	0.011
Rsbn1	rosbin, round spermatid basic protein 1	0.011
Sdhc	succinate dehydrogenase complex, subunit C, integral membrane protein	0.011	Human
Sdhb	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.010
Shh	sonic hedgehog	0.010
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.010
Epb4.1l5	erythrocyte protein band 4.1-like 5	0.010
Slc25a10	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10	0.010
Top2b	topoisomerase (DNA) II beta	0.010
Pdha1	pyruvate dehydrogenase E1 alpha 1	0.010