IMP

Process View

Mus musculus

1 genes annotated in mouse

rhombomere formation

The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "rhombomere formation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "rhombomere formation" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	0.998
Hoxa1	homeobox A1	0.995
Jag1	jagged 1	0.982
Chd7	chromodomain helicase DNA binding protein 7	0.911
Foxc1	forkhead box C1	0.909
Lmx1a	LIM homeobox transcription factor 1 alpha	0.852
Tbx1	T-box 1	0.849
Gli3	GLI-Kruppel family member GLI3	0.832
Fgfr1	fibroblast growth factor receptor 1	0.813
Gata3	GATA binding protein 3	0.797
Vangl2	vang-like 2 (van gogh, Drosophila)	0.788
Gbx2	gastrulation brain homeobox 2	0.779
Foxc2	forkhead box C2	0.762
Nab2	Ngfi-A binding protein 2	0.720
Eya1	eyes absent 1 homolog (Drosophila)	0.718
Dll1	delta-like 1 (Drosophila)	0.709
Ntf3	neurotrophin 3	0.662
Shh	sonic hedgehog	0.626
Notch1	Notch gene homolog 1 (Drosophila)	0.607	Zebrafish
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.541
Gata4	GATA binding protein 4	0.530
Fos	FBJ osteosarcoma oncogene	0.507
Foxg1	forkhead box G1	0.501
Foxo1	forkhead box O1	0.486
Isl1	ISL1 transcription factor, LIM/homeodomain	0.479
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.455
Fgf8	fibroblast growth factor 8	0.443
Fgfr2	fibroblast growth factor receptor 2	0.419
Emx2	empty spiracles homolog 2 (Drosophila)	0.415
Spry2	sprouty homolog 2 (Drosophila)	0.397
Efnb2	ephrin B2	0.383	Zebrafish
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.378
Psen1	presenilin 1	0.367
Lhx1	LIM homeobox protein 1	0.366
Gdnf	glial cell line derived neurotrophic factor	0.353
Smo	smoothened homolog (Drosophila)	0.325
Egr1	early growth response 1	0.318	Mouse
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.308
Notch2	Notch gene homolog 2 (Drosophila)	0.306
Hoxa2	homeobox A2	0.297
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.293
Fosb	FBJ osteosarcoma oncogene B	0.265
Nog	noggin	0.231
Hes1	hairy and enhancer of split 1 (Drosophila)	0.225
Jag2	jagged 2	0.223
Pax3	paired box gene 3	0.206
Pitx2	paired-like homeodomain transcription factor 2	0.189
Lhx9	LIM homeobox protein 9	0.188
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.186
Rxra	retinoid X receptor alpha	0.185
Nos3	nitric oxide synthase 3, endothelial cell	0.185
Ret	ret proto-oncogene	0.183
Epha4	Eph receptor A4	0.179
Bnc1	basonuclin 1	0.176
Tcfap2a	transcription factor AP-2, alpha	0.156
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.152
Jun	Jun oncogene	0.151
Egr2	early growth response 2	0.149
Otx2	orthodenticle homolog 2 (Drosophila)	0.147
Bcl2	B-cell leukemia/lymphoma 2	0.146
Ephb2	Eph receptor B2	0.141
Sox9	SRY-box containing gene 9	0.141
Msx1	homeobox, msh-like 1	0.127
Bmp4	bone morphogenetic protein 4	0.125
Tbx10	T-box 10	0.120
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.116
Sox2	SRY-box containing gene 2	0.112
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.110
Hand2	heart and neural crest derivatives expressed transcript 2	0.109
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.109
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.107
Dlx5	distal-less homeobox 5	0.101
Hmx3	H6 homeobox 3	0.099
Wiz	widely-interspaced zinc finger motifs	0.098
Junb	Jun-B oncogene	0.094
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.094
En1	engrailed 1	0.087
Socs3	suppressor of cytokine signaling 3	0.087
Ar	androgen receptor	0.083
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.082
Efna2	ephrin A2	0.082
Zeb1	zinc finger E-box binding homeobox 1	0.081
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.080
Efnb1	ephrin B1	0.076
Tgfb2	transforming growth factor, beta 2	0.075
Chrd	chordin	0.075
Nrg1	neuregulin 1	0.074
Hoxb2	homeobox B2	0.068
Bdnf	brain derived neurotrophic factor	0.067
Otx1	orthodenticle homolog 1 (Drosophila)	0.067
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.063
Phox2b	paired-like homeobox 2b	0.063
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.063
Zfp651	zinc finger protein 651	0.061
Tgif2	TGFB-induced factor homeobox 2	0.059
Ptgs2	prostaglandin-endoperoxide synthase 2	0.058
Hoxc8	homeobox C8	0.057
Fgf3	fibroblast growth factor 3	0.057
Hdac7	histone deacetylase 7	0.056
Hoxa11	homeobox A11	0.056
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.056
Plxna3	plexin A3	0.054
Nynrin	NYN domain and retroviral integrase containing	0.053
Robo3	roundabout homolog 3 (Drosophila)	0.052
Pbx1	pre B-cell leukemia transcription factor 1	0.051
Lamc1	laminin, gamma 1	0.050
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.049
Zic2	zinc finger protein of the cerebellum 2	0.049
Vegfa	vascular endothelial growth factor A	0.049
Fosl2	fos-like antigen 2	0.049
Sars2	seryl-aminoacyl-tRNA synthetase 2	0.048
Btg2	B-cell translocation gene 2, anti-proliferative	0.048
Ctnnb1	catenin (cadherin associated protein), beta 1	0.046
Ebf3	early B-cell factor 3	0.046
Nf1	neurofibromatosis 1	0.046
Rnf208	ring finger protein 208	0.045
Dusp1	dual specificity phosphatase 1	0.045
Rarb	retinoic acid receptor, beta	0.045
Efs	embryonal Fyn-associated substrate	0.043
Foxd2	forkhead box D2	0.043
Emid2	EMI domain containing 2	0.042
Myo1e	myosin IE	0.041
Psen2	presenilin 2	0.041
Sh3rf1	SH3 domain containing ring finger 1	0.040
Hes5	hairy and enhancer of split 5 (Drosophila)	0.039
Nab1	Ngfi-A binding protein 1	0.039
Sox7	SRY-box containing gene 7	0.038
Cbln1	cerebellin 1 precursor protein	0.037
Prrx1	paired related homeobox 1	0.036
Foxi1	forkhead box I1	0.036
Tbx2	T-box 2	0.036
Wnt1	wingless-related MMTV integration site 1	0.035
Igf2	insulin-like growth factor 2	0.034
Lef1	lymphoid enhancer binding factor 1	0.032
Pou4f3	POU domain, class 4, transcription factor 3	0.032
Dll4	delta-like 4 (Drosophila)	0.032
Rb1	retinoblastoma 1	0.032
Phldb1	pleckstrin homology-like domain, family B, member 1	0.031
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.031
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.030
Sox11	SRY-box containing gene 11	0.030
Mbd6	methyl-CpG binding domain protein 6	0.029
Gli2	GLI-Kruppel family member GLI2	0.029
Nckap5l	NCK-associated protein 5-like	0.029
Kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.029
Rnpepl1	arginyl aminopeptidase (aminopeptidase B)-like 1	0.028
Alk	anaplastic lymphoma kinase	0.028
Ikzf4	IKAROS family zinc finger 4	0.028
Zfp362	zinc finger protein 362	0.027
Bcl11b	B-cell leukemia/lymphoma 11B	0.027
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.026
Foxi3	forkhead box I3	0.026
Fgfr3	fibroblast growth factor receptor 3	0.026
Slc26a4	solute carrier family 26, member 4	0.025
Mark1	MAP/microtubule affinity-regulating kinase 1	0.025
Adam19	a disintegrin and metallopeptidase domain 19 (meltrin beta)	0.025
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.025
Osr1	odd-skipped related 1 (Drosophila)	0.025
Zfpm2	zinc finger protein, multitype 2	0.025
Spry1	sprouty homolog 1 (Drosophila)	0.024
Hand1	heart and neural crest derivatives expressed transcript 1	0.024
Wt1	Wilms tumor 1 homolog	0.024	Mouse
Usf2	upstream transcription factor 2	0.024
Ncor2	nuclear receptor co-repressor 2	0.024
Ednra	endothelin receptor type A	0.024
Zfp36	zinc finger protein 36	0.023
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.023
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.023
Csrnp1	cysteine-serine-rich nuclear protein 1	0.022
Ski	ski sarcoma viral oncogene homolog (avian)	0.022
Hoxa4	homeobox A4	0.022
Pou3f1	POU domain, class 3, transcription factor 1	0.022
Klf3	Kruppel-like factor 3 (basic)	0.022
Gata6	GATA binding protein 6	0.022
Stk40	serine/threonine kinase 40	0.021
Itga3	integrin alpha 3	0.021
Atf3	activating transcription factor 3	0.021
Lhb	luteinizing hormone beta	0.021
Epn1	epsin 1	0.021
Hoxd11	homeobox D11	0.021
Dock1	dedicator of cytokinesis 1	0.020
Inha	inhibin alpha	0.020
Arid1a	AT rich interactive domain 1A (SWI-like)	0.020
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.020
Ctnnbip1	catenin beta interacting protein 1	0.020
Wnt6	wingless-related MMTV integration site 6	0.020
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.020
Grip1	glutamate receptor interacting protein 1	0.019
Cxcr4	chemokine (C-X-C motif) receptor 4	0.019
Efna5	ephrin A5	0.019
Amh	anti-Mullerian hormone	0.019
Dst	dystonin	0.019
Ephb3	Eph receptor B3	0.019
Plxna1	plexin A1	0.018
Sox10	SRY-box containing gene 10	0.018
Tead3	TEA domain family member 3	0.018
Atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.018
Adcy4	adenylate cyclase 4	0.018
Npy	neuropeptide Y	0.018
Fam19a5	family with sequence similarity 19, member A5	0.018
Lhx3	LIM homeobox protein 3	0.017
Aatk	apoptosis-associated tyrosine kinase	0.017
Col4a2	collagen, type IV, alpha 2	0.017
Sim2	single-minded homolog 2 (Drosophila)	0.017
Strc	stereocilin	0.017
Phox2a	paired-like homeobox 2a	0.017
Snai1	snail homolog 1 (Drosophila)	0.017
Zfp385a	zinc finger protein 385A	0.017
Cyr61	cysteine rich protein 61	0.017
Spns2	spinster homolog 2 (Drosophila)	0.017
Mtss1l	metastasis suppressor 1-like	0.016
Nrtn	neurturin	0.016
Egfr	epidermal growth factor receptor	0.016
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.016
Irf2bp1	interferon regulatory factor 2 binding protein 1	0.016
T	brachyury	0.016
Cic	capicua homolog (Drosophila)	0.016
Gdf15	growth differentiation factor 15	0.016
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.015
Jph3	junctophilin 3	0.015
Cckbr	cholecystokinin B receptor	0.015
Srrm4	serine/arginine repetitive matrix 4	0.015
Htr6	5-hydroxytryptamine (serotonin) receptor 6	0.015
Fgf4	fibroblast growth factor 4	0.015
Neurl4	neuralized homolog 4 (Drosophila)	0.015
Sall3	sal-like 3 (Drosophila)	0.015
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.015
Evx2	even skipped homeotic gene 2 homolog	0.015
Bcl6b	B-cell CLL/lymphoma 6, member B	0.015
Fzd8	frizzled homolog 8 (Drosophila)	0.015
Smad7	MAD homolog 7 (Drosophila)	0.015
Fgf10	fibroblast growth factor 10	0.015
Adam11	a disintegrin and metallopeptidase domain 11	0.015
St6galnac3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	0.015
Ece1	endothelin converting enzyme 1	0.015
Rarg	retinoic acid receptor, gamma	0.015
Sim1	single-minded homolog 1 (Drosophila)	0.014
Apln	apelin	0.014
Zfp503	zinc finger protein 503	0.014
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.014
Col2a1	collagen, type II, alpha 1	0.014
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.014
Meox2	mesenchyme homeobox 2	0.014
Notch3	Notch gene homolog 3 (Drosophila)	0.014	Zebrafish
Egfl7	EGF-like domain 7	0.014
Gli1	GLI-Kruppel family member GLI1	0.014
Midn	midnolin	0.014
Tcf15	transcription factor 15	0.014
Ghrhr	growth hormone releasing hormone receptor	0.014
Ankrd11	ankyrin repeat domain 11	0.014
Prrx2	paired related homeobox 2	0.014
Llgl1	lethal giant larvae homolog 1 (Drosophila)	0.014
Hoxc6	homeobox C6	0.014
Abcd1	ATP-binding cassette, sub-family D (ALD), member 1	0.014
Dlx2	distal-less homeobox 2	0.014
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.014
Syt7	synaptotagmin VII	0.014
Thra	thyroid hormone receptor alpha	0.014
Rtbdn	retbindin	0.014
Efna3	ephrin A3	0.013
Dusp5	dual specificity phosphatase 5	0.013
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.013
Epha2	Eph receptor A2	0.013
Ier5l	immediate early response 5-like	0.013
Mab21l2	mab-21-like 2 (C. elegans)	0.013
Tle2	transducin-like enhancer of split 2, homolog of Drosophila E(spl)	0.013
Zfr2	zinc finger RNA binding protein 2	0.013
Gata1	GATA binding protein 1	0.013
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.013
Bmp7	bone morphogenetic protein 7	0.013
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.013
Dmrt3	doublesex and mab-3 related transcription factor 3	0.013
Adamts7	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7	0.013
Prr12	proline rich 12	0.013
Apc2	adenomatosis polyposis coli 2	0.013
Unc5c	unc-5 homolog C (C. elegans)	0.013
Stc2	stanniocalcin 2	0.013
Mybpc3	myosin binding protein C, cardiac	0.012
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.012
Ptk7	PTK7 protein tyrosine kinase 7	0.012
Myod1	myogenic differentiation 1	0.012
She	src homology 2 domain-containing transforming protein E	0.012
Fscn1	fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus)	0.012
Cabp2	calcium binding protein 2	0.012
Pkd1	polycystic kidney disease 1 homolog	0.012
Egr3	early growth response 3	0.012	Mouse
Irx4	Iroquois related homeobox 4 (Drosophila)	0.012
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.012
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.012
Mageb3	melanoma antigen, family B, 3	0.012
Zmiz2	zinc finger, MIZ-type containing 2	0.012
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.012
Pnoc	prepronociceptin	0.012
Col7a1	collagen, type VII, alpha 1	0.012
Sox4	SRY-box containing gene 4	0.012
Nadk	NAD kinase	0.012
Flt4	FMS-like tyrosine kinase 4	0.012
Dusp2	dual specificity phosphatase 2	0.012
Tbx3	T-box 3	0.011
Sox13	SRY-box containing gene 13	0.011
S1pr2	sphingosine-1-phosphate receptor 2	0.011
S1pr3	sphingosine-1-phosphate receptor 3	0.011
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.011
Ier2	immediate early response 2	0.011
Khk	ketohexokinase	0.011
Tlx2	T-cell leukemia, homeobox 2	0.011
Col4a3	collagen, type IV, alpha 3	0.011
Slco5a1	solute carrier organic anion transporter family, member 5A1	0.011
Hoxb6	homeobox B6	0.011
Hmx2	H6 homeobox 2	0.011
Hoxd1	homeobox D1	0.011
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.011
Gsx1	GS homeobox 1	0.011
Ptch1	patched homolog 1	0.011
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.011
Gpr27	G protein-coupled receptor 27	0.011
Wnt4	wingless-related MMTV integration site 4	0.011
Nhlh1	nescient helix loop helix 1	0.011
Tert	telomerase reverse transcriptase	0.011
6330416G13Rik	RIKEN cDNA 6330416G13 gene	0.011
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.011
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.011
Irx1	Iroquois related homeobox 1 (Drosophila)	0.011
Vax1	ventral anterior homeobox containing gene 1	0.011
Adra2b	adrenergic receptor, alpha 2b	0.011
Myo6	myosin VI	0.011
Pou4f2	POU domain, class 4, transcription factor 2	0.011
Kiss1	KiSS-1 metastasis-suppressor	0.011
Hoxd3	homeobox D3	0.011
Cxcl2	chemokine (C-X-C motif) ligand 2	0.011
Insm1	insulinoma-associated 1	0.011
Lama5	laminin, alpha 5	0.010
Ahr	aryl-hydrocarbon receptor	0.010
Dpysl4	dihydropyrimidinase-like 4	0.010
Slc26a5	solute carrier family 26, member 5	0.010
Celf4	CUGBP, Elav-like family member 4	0.010
Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	0.010
H1fx	H1 histone family, member X	0.010
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.010
Ihh	Indian hedgehog	0.010
Ncs1	neuronal calcium sensor 1	0.010
Smad6	MAD homolog 6 (Drosophila)	0.010
Gal	galanin	0.010
Efna1	ephrin A1	0.010
Hoxc4	homeobox C4	0.010
Col13a1	collagen, type XIII, alpha 1	0.010
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.010
Col11a1	collagen, type XI, alpha 1	0.010
Scube3	signal peptide, CUB domain, EGF-like 3	0.010
Gjb5	gap junction protein, beta 5	0.010
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.010
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.010
Zbtb46	zinc finger and BTB domain containing 46	0.010