IMP
Process View
The network for 'negative regulation of reactive oxygen species biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of reactive oxygen species biosynthetic process
Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pparg | peroxisome proliferator activated receptor gamma | 0.957 | |
| Il6 | interleukin 6 | 0.938 | |
| Il1r1 | interleukin 1 receptor, type I | 0.916 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.905 | |
| Tlr4 | toll-like receptor 4 | 0.862 | |
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.834 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.780 | |
| Lyz2 | lysozyme 2 | 0.766 | |
| Lepr | leptin receptor | 0.720 | |
| Ptrf | polymerase I and transcript release factor | 0.688 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.660 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.531 | |
| Cav1 | caveolin 1, caveolae protein | 0.456 | |
| Lep | leptin | 0.427 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.397 | |
| Dmd | dystrophin, muscular dystrophy | 0.286 | |
| Ghr | growth hormone receptor | 0.275 | |
| Tnf | tumor necrosis factor | 0.241 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.229 | |
| Mmp9 | matrix metallopeptidase 9 | 0.213 | |
| Apoe | apolipoprotein E | 0.207 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.203 | |
| Il6st | interleukin 6 signal transducer | 0.173 | |
| Nos1 | nitric oxide synthase 1, neuronal | 0.156 | |
| Cd44 | CD44 antigen | 0.154 | |
| Il10 | interleukin 10 | 0.123 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.112 | |
| Sgca | sarcoglycan, alpha (dystrophin-associated glycoprotein) | 0.081 | |
| Ncoa3 | nuclear receptor coactivator 3 | 0.073 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.073 | |
| Cd36 | CD36 antigen | 0.072 | |
| Ldlr | low density lipoprotein receptor | 0.072 | |
| Col1a1 | collagen, type I, alpha 1 | 0.067 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.065 | |
| Plin1 | perilipin 1 | 0.064 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.063 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.061 | |
| Esr2 | estrogen receptor 2 (beta) | 0.053 | |
| Arid1b | AT rich interactive domain 1B (SWI-like) | 0.046 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.046 | |
| Spp1 | secreted phosphoprotein 1 | 0.045 | |
| Nfil3 | nuclear factor, interleukin 3, regulated | 0.044 | |
| Lpin1 | lipin 1 | 0.040 | |
| Stat6 | signal transducer and activator of transcription 6 | 0.038 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.038 | |
| C3 | complement component 3 | 0.033 | |
| Insr | insulin receptor | 0.031 | |
| Tlr2 | toll-like receptor 2 | 0.030 | |
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.030 | |
| Junb | Jun-B oncogene | 0.029 | |
| Socs3 | suppressor of cytokine signaling 3 | 0.029 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.029 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.028 | |
| Clcn5 | chloride channel 5 | 0.027 | |
| Lif | leukemia inhibitory factor | 0.026 | |
| Stat5b | signal transducer and activator of transcription 5B | 0.025 | |
| Pnpla2 | patatin-like phospholipase domain containing 2 | 0.021 | |
| Plau | plasminogen activator, urokinase | 0.017 | |
| Adipoq | adiponectin, C1Q and collagen domain containing | 0.017 | |
| Foxp3 | forkhead box P3 | 0.016 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.015 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.015 | |
| Gria1 | glutamate receptor, ionotropic, AMPA1 (alpha 1) | 0.014 | |
| Ripk1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.014 | |
| Pmp22 | peripheral myelin protein 22 | 0.013 | |
| Stat5a | signal transducer and activator of transcription 5A | 0.013 | |
| Ahr | aryl-hydrocarbon receptor | 0.012 | |
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | 0.012 | |
| Nedd4l | neural precursor cell expressed, developmentally down-regulated gene 4-like | 0.012 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.011 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.011 | |
| Prlhr | prolactin releasing hormone receptor | 0.011 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.011 | |
| Dusp1 | dual specificity phosphatase 1 | 0.010 | |
| Lmna | lamin A | 0.010 | |
| Egr1 | early growth response 1 | 0.010 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.975 | |
| CAV2 | caveolin 2 | 0.687 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.254 | |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.242 | |
| IL10RA | interleukin 10 receptor, alpha | 0.157 | |
| PTEN | phosphatase and tensin homolog | 0.126 | |
| EGFR | epidermal growth factor receptor | 0.125 | |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.096 | |
| JAK2 | Janus kinase 2 | 0.093 | |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.093 | |
| IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.082 | |
| MPDZ | multiple PDZ domain protein | 0.078 | |
| CALCA | calcitonin-related polypeptide alpha | 0.073 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.070 | |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.066 | |
| JAK1 | Janus kinase 1 | 0.064 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.062 | |
| EGR2 | early growth response 2 | 0.061 | |
| F2R | coagulation factor II (thrombin) receptor | 0.059 | |
| BCL3 | B-cell CLL/lymphoma 3 | 0.056 | |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.054 | |
| TNIP2 | TNFAIP3 interacting protein 2 | 0.053 | |
| PRKCDBP | protein kinase C, delta binding protein | 0.051 | |
| SSTR2 | somatostatin receptor 2 | 0.048 | |
| IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.048 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.045 | |
| STAT5A | signal transducer and activator of transcription 5A | 0.045 | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.043 | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.041 | |
| OSBPL8 | oxysterol binding protein-like 8 | 0.039 | |
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.038 | |
| DLG2 | discs, large homolog 2 (Drosophila) | 0.038 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.033 | |
| C2orf18 | chromosome 2 open reading frame 18 | 0.031 | |
| SDPR | serum deprivation response | 0.031 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.030 | |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.029 | |
| SSTR3 | somatostatin receptor 3 | 0.029 | |
| TXNRD1 | thioredoxin reductase 1 | 0.029 | |
| MBNL1 | muscleblind-like (Drosophila) | 0.028 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.028 | |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.027 | |
| NRIP1 | nuclear receptor interacting protein 1 | 0.026 | |
| PIAS3 | protein inhibitor of activated STAT, 3 | 0.026 | |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.026 | |
| SHANK1 | SH3 and multiple ankyrin repeat domains 1 | 0.025 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.025 | |
| DLC1 | deleted in liver cancer 1 | 0.024 | |
| KCNF1 | potassium voltage-gated channel, subfamily F, member 1 | 0.024 | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.024 | |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.024 | |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 | 0.024 | |
| CDK17 | cyclin-dependent kinase 17 | 0.023 | |
| SPAG9 | sperm associated antigen 9 | 0.021 | |
| KDM2A | lysine (K)-specific demethylase 2A | 0.021 | |
| GJA4 | gap junction protein, alpha 4, 37kDa | 0.021 | |
| DRD2 | dopamine receptor D2 | 0.019 | |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.018 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.018 | |
| DOK4 | docking protein 4 | 0.018 | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.018 | |
| CISH | cytokine inducible SH2-containing protein | 0.018 | |
| PTRF | polymerase I and transcript release factor | 0.017 | |
| SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.017 | |
| CD44 | CD44 molecule (Indian blood group) | 0.017 | |
| FSCN2 | fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus) | 0.017 | |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.017 | |
| EDNRB | endothelin receptor type B | 0.017 | |
| PROCR | protein C receptor, endothelial | 0.017 | |
| LTK | leukocyte receptor tyrosine kinase | 0.016 | |
| CD59 | CD59 molecule, complement regulatory protein | 0.016 | |
| HRH3 | histamine receptor H3 | 0.016 | |
| BLK | B lymphoid tyrosine kinase | 0.016 | |
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.016 | |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) | 0.016 | |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.016 | |
| IRS1 | insulin receptor substrate 1 | 0.016 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.016 | |
| PNOC | prepronociceptin | 0.016 | |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.016 | |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 | 0.015 | |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.015 | |
| ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.015 | |
| MORC4 | MORC family CW-type zinc finger 4 | 0.015 | |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.015 | |
| OGDHL | oxoglutarate dehydrogenase-like | 0.015 | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.015 | |
| CORT | cortistatin | 0.015 | |
| ERBB2IP | erbb2 interacting protein | 0.015 | |
| CALCRL | calcitonin receptor-like | 0.015 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.015 | |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.015 | |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.015 | |
| EMX1 | empty spiracles homeobox 1 | 0.015 | |
| SP1 | Sp1 transcription factor | 0.015 | |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.015 | |
| SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.015 | |
| OXT | oxytocin, prepropeptide | 0.015 | |
| STAT2 | signal transducer and activator of transcription 2, 113kDa | 0.015 | |
| FOSL2 | FOS-like antigen 2 | 0.015 |