The network for 'myeloid cell activation involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myeloid cell activation involved in immune response

A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.

Mus musculus
Name Description Probability Func Analog Organism
Cd247 CD247 antigen 0.989
Ikzf1 IKAROS family zinc finger 1 0.956
Ptprc protein tyrosine phosphatase, receptor type, C 0.934
Ccr2 chemokine (C-C motif) receptor 2 0.920
Cd19 CD19 antigen 0.917
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.907
Ccr6 chemokine (C-C motif) receptor 6 0.895
Csf2rb2 colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) 0.877
AF251705 cDNA sequence AF251705 0.874
Hcst hematopoietic cell signal transducer 0.861
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.828
Mefv Mediterranean fever 0.817
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.814
Inpp5d inositol polyphosphate-5-phosphatase D 0.771
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.710
Nfam1 Nfat activating molecule with ITAM motif 1 0.688
Prkce protein kinase C, epsilon 0.684
Ccr1 chemokine (C-C motif) receptor 1 0.663
Il4 interleukin 4 0.653
Lat linker for activation of T cells 0.650
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.615
Ifng interferon gamma 0.590
Grb2 growth factor receptor bound protein 2 0.576
Grap2 GRB2-related adaptor protein 2 0.571
Cd22 CD22 antigen 0.553
Cd4 CD4 antigen 0.545
Itgax integrin alpha X 0.539
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.531
Il2rb interleukin 2 receptor, beta chain 0.524
Prf1 perforin 1 (pore forming protein) 0.516
Cd7 CD7 antigen 0.499
Cd40 CD40 antigen 0.414
C5ar1 complement component 5a receptor 1 0.401
Met met proto-oncogene 0.385
S1pr4 sphingosine-1-phosphate receptor 4 0.352
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.342
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.338
Fes feline sarcoma oncogene 0.335
Xcr1 chemokine (C motif) receptor 1 0.320
Mmp9 matrix metallopeptidase 9 0.315
Efna1 ephrin A1 0.314
Cd14 CD14 antigen 0.304
Tnf tumor necrosis factor 0.299
Fcgr1 Fc receptor, IgG, high affinity I 0.289
Csf1r colony stimulating factor 1 receptor 0.288
Prdm1 PR domain containing 1, with ZNF domain 0.275
Ncf1 neutrophil cytosolic factor 1 0.252
Il2 interleukin 2 0.240
Myo1f myosin IF 0.233
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.230
Ptpre protein tyrosine phosphatase, receptor type, E 0.227
Cd6 CD6 antigen 0.225
Cxcr2 chemokine (C-X-C motif) receptor 2 0.222
Galnt6 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 0.222
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.216
Cbl Casitas B-lineage lymphoma 0.206
Acvrl1 activin A receptor, type II-like 1 0.205
Snai1 snail homolog 1 (Drosophila) 0.202
Itk IL2-inducible T-cell kinase 0.194
Efnb2 ephrin B2 0.193
Pdcd1 programmed cell death 1 0.190
Mmp8 matrix metallopeptidase 8 0.189
Cd3e CD3 antigen, epsilon polypeptide 0.186
Selp selectin, platelet 0.181
Cd96 CD96 antigen 0.179
Stat6 signal transducer and activator of transcription 6 0.177
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.177
Fyn Fyn proto-oncogene 0.175
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.173
Lcp2 lymphocyte cytosolic protein 2 0.172
Ldb3 LIM domain binding 3 0.171
Ifngr1 interferon gamma receptor 1 0.167
Irf5 interferon regulatory factor 5 0.167
Cd8a CD8 antigen, alpha chain 0.167
Trem3 triggering receptor expressed on myeloid cells 3 0.166
Ncr1 natural cytotoxicity triggering receptor 1 0.165
Cnr2 cannabinoid receptor 2 (macrophage) 0.164
Aim2 absent in melanoma 2 0.160
Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide 0.160
Sit1 suppression inducing transmembrane adaptor 1 0.150
P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7 0.145
Fcrla Fc receptor-like A 0.142
Cd300lb CD300 antigen like family member B 0.136
Cd300a CD300A antigen 0.133
Sfpi1 SFFV proviral integration 1 0.131
Mb myoglobin 0.126
Cx3cr1 chemokine (C-X3-C) receptor 1 0.125
Il1rn interleukin 1 receptor antagonist 0.123
Sirpa signal-regulatory protein alpha 0.123
Tlr2 toll-like receptor 2 0.122
Trpv1 transient receptor potential cation channel, subfamily V, member 1 0.118
Fgd3 FYVE, RhoGEF and PH domain containing 3 0.114
Fasl Fas ligand (TNF superfamily, member 6) 0.114
Icos inducible T-cell co-stimulator 0.114
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.113
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.113
Kit kit oncogene 0.112
Lair1 leukocyte-associated Ig-like receptor 1 0.110
Ccl3 chemokine (C-C motif) ligand 3 0.110
Msr1 macrophage scavenger receptor 1 0.109
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
SYK spleen tyrosine kinase 0.485
CCR5 chemokine (C-C motif) receptor 5 0.435
BLNK B-cell linker 0.369
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.209
NRP1 neuropilin 1 0.180
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.165
EGFR epidermal growth factor receptor 0.153
LAT linker for activation of T cells 0.123
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.117
SNAP23 synaptosomal-associated protein, 23kDa 0.110
IL2RG interleukin 2 receptor, gamma 0.103
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.100
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.089
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.084
GAB1 GRB2-associated binding protein 1 0.083
SLA Src-like-adaptor 0.081
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.074
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.066
IL4R interleukin 4 receptor 0.061
UBASH3B ubiquitin associated and SH3 domain containing B 0.056
CDH5 cadherin 5, type 2 (vascular endothelium) 0.056
CAV1 caveolin 1, caveolae protein, 22kDa 0.055
CXCL9 chemokine (C-X-C motif) ligand 9 0.055
C19orf50 chromosome 19 open reading frame 50 0.044
VAV1 vav 1 guanine nucleotide exchange factor 0.042
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.040
HCK hemopoietic cell kinase 0.038
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.037
CAV2 caveolin 2 0.036
SOS1 son of sevenless homolog 1 (Drosophila) 0.035
CCL2 chemokine (C-C motif) ligand 2 0.034
CCR7 chemokine (C-C motif) receptor 7 0.031
TFF1 trefoil factor 1 0.027
CCL4 chemokine (C-C motif) ligand 4 0.025
ANXA2 annexin A2 0.024
FYB FYN binding protein 0.022
CRH corticotropin releasing hormone 0.021
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.021
PPL periplakin 0.021
FGFR1 fibroblast growth factor receptor 1 0.021
PDGFA platelet-derived growth factor alpha polypeptide 0.020
IDE insulin-degrading enzyme 0.020
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.019
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.019
ANKRD27 ankyrin repeat domain 27 (VPS9 domain) 0.019
PLCG1 phospholipase C, gamma 1 0.019
IL4 interleukin 4 0.019
NLRC4 NLR family, CARD domain containing 4 0.018
IL10RA interleukin 10 receptor, alpha 0.018
CCL22 chemokine (C-C motif) ligand 22 0.018
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.018
TNF tumor necrosis factor 0.017
VCAM1 vascular cell adhesion molecule 1 0.017
CCL8 chemokine (C-C motif) ligand 8 0.017
CCL5 chemokine (C-C motif) ligand 5 0.016
VEGFA vascular endothelial growth factor A 0.016
BAI1 brain-specific angiogenesis inhibitor 1 0.015
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.015
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.015
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.014
MEFV Mediterranean fever 0.014
CCL7 chemokine (C-C motif) ligand 7 0.014
IL10 interleukin 10 0.014
CCL19 chemokine (C-C motif) ligand 19 0.013
ZNF746 zinc finger protein 746 0.013
IFNG interferon, gamma 0.013
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.013
CCR1 chemokine (C-C motif) receptor 1 0.012
CXCL3 chemokine (C-X-C motif) ligand 3 0.012
CCL13 chemokine (C-C motif) ligand 13 0.012
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.011
GRB2 growth factor receptor-bound protein 2 0.011
PGF placental growth factor 0.011
TRAF1 TNF receptor-associated factor 1 0.011
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.011
DPP4 dipeptidyl-peptidase 4 0.010
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.010
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.537
Morf4l2 mortality factor 4 like 2 0.348
Csf1 colony stimulating factor 1 (macrophage) 0.152
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.143
Ptprc protein tyrosine phosphatase, receptor type, C 0.115
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.087
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.075
Cybb cytochrome b-245, beta polypeptide 0.074
Arl11 ADP-ribosylation factor-like 11 0.062
Eif4h eukaryotic translation initiation factor 4H 0.061
Calm1 calmodulin 1 0.061
Ciita class II, major histocompatibility complex, transactivator 0.056
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.055
Tuba1c tubulin, alpha 1C 0.053
Ppp2ca protein phosphatase 2, catalytic subunit, alpha isoform 0.052
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.051
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.049
Ptafr platelet-activating factor receptor 0.045
Cd38 CD38 molecule 0.045
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.042
Sirpa signal-regulatory protein alpha 0.042
Adar adenosine deaminase, RNA-specific 0.042
Tnfrsf8 tumor necrosis factor receptor superfamily, member 8 0.042
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.041
RGD1310262 hypothetical LOC304650 0.040
Lat linker for activation of T cells 0.039
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.037
Actg1 actin, gamma 1 0.036
Txnrd1 thioredoxin reductase 1 0.036
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.036
Cxcr3 chemokine (C-X-C motif) receptor 3 0.034
C5ar1 complement component 5a receptor 1 0.033
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.033
Cd247 Cd247 molecule 0.033
RGD1304644 similar to RIKEN cDNA 2310046K01 0.032
Atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.032
Pgam1 phosphoglycerate mutase 1 (brain) 0.032
Arhgap25 Rho GTPase activating protein 25 0.031
Gzmk granzyme K 0.030
Rraga Ras-related GTP binding A 0.030
Calm2 calmodulin 2 0.029
Tlr4 toll-like receptor 4 0.028
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.027
Ppp2cb protein phosphatase 2, catalytic subunit, beta isoform 0.027
Tcf4 transcription factor 4 0.026
Aplnr apelin receptor 0.026
Ccr5 chemokine (C-C motif) receptor 5 0.026
Ctse cathepsin E 0.026
Fgf16 fibroblast growth factor 16 0.026
Tgfbr3 transforming growth factor, beta receptor III 0.026
Bcl3 B-cell CLL/lymphoma 3 0.024
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.024
Prl3d4 prolactin family 3, subfamily d, member 4 0.023
Cd86 CD86 molecule 0.022
Acrv1 acrosomal vesicle protein 1 0.022
Sdc3 syndecan 3 0.021
Hck hemopoietic cell kinase 0.021
Ncr1 natural cytotoxicity triggering receptor 1 0.021
Padi3 peptidyl arginine deiminase, type III 0.021
Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) 0.021
Cltc clathrin, heavy chain (Hc) 0.021
B3gnt7 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 0.021
Slc24a6 solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 0.020
Ly86 lymphocyte antigen 86 0.019
Psd4 pleckstrin and Sec7 domain containing 4 0.019
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.018
Ncan neurocan 0.018
Slc9a1 solute carrier family 9 (sodium/hydrogen exchanger), member 1 0.018
Ednra endothelin receptor type A 0.018
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.018
Dock8 dedicator of cytokinesis 8 0.018
Irf5 interferon regulatory factor 5 0.018
Il2rb interleukin 2 receptor, beta 0.017
Cdcp1 CUB domain containing protein 1 0.017
Folr2 folate receptor 2 (fetal) 0.017
Mcpt2 mast cell protease 2 0.017
Pde3a phosphodiesterase 3A, cGMP inhibited 0.017
Tbxas1 thromboxane A synthase 1, platelet 0.017
Plaur plasminogen activator, urokinase receptor 0.017
Cfp complement factor properdin 0.016
Tgfbr2 transforming growth factor, beta receptor II 0.016
Mutyh mutY homolog (E. coli) 0.016
Neurl3 neuralized homolog 3 (Drosophila) 0.016
Cd8a CD8a molecule 0.016
Il1b interleukin 1 beta 0.016
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.016
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.015
Skap2 src kinase associated phosphoprotein 2 0.015
Inpp5d inositol polyphosphate-5-phosphatase D 0.015
Hrh2 histamine receptor H 2 0.015
Igh-6 immunoglobulin heavy chain 6 0.015
Faslg Fas ligand (TNF superfamily, member 6) 0.015
Dchs1 dachsous 1 (Drosophila) 0.015
Il17ra interleukin 17 receptor A 0.014
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.014
Nptn neuroplastin 0.014
App amyloid beta (A4) precursor protein 0.014
Dnase1l3 deoxyribonuclease 1-like 3 0.014
Zwint ZW10 interactor 0.014
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.014
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism