The network for 'myeloid cell homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myeloid cell homeostasis

The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.

Mus musculus
Name Description Probability Func Analog Organism
Spna1 spectrin alpha 1 0.999
Ank1 ankyrin 1, erythroid 0.997
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.996
Epor erythropoietin receptor 0.994
Hbb-b2 hemoglobin, beta adult minor chain 0.993
Stat3 signal transducer and activator of transcription 3 0.993
Smad4 MAD homolog 4 (Drosophila) 0.991
Mapk14 mitogen-activated protein kinase 14 0.991
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.986
Kit kit oncogene 0.986
Gata4 GATA binding protein 4 0.971
Pbx1 pre B-cell leukemia transcription factor 1 0.970
Gata1 GATA binding protein 1 0.952
Ikzf1 IKAROS family zinc finger 1 0.948
Smad1 MAD homolog 1 (Drosophila) 0.934
Tal1 T-cell acute lymphocytic leukemia 1 0.912
Pten phosphatase and tensin homolog 0.898
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.884
Nos3 nitric oxide synthase 3, endothelial cell 0.883
Trp53 transformation related protein 53 0.877
Gypa glycophorin A 0.877
Stat1 signal transducer and activator of transcription 1 0.864
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.849
Lyz2 lysozyme 2 0.848
Wt1 Wilms tumor 1 homolog 0.834
Ptprc protein tyrosine phosphatase, receptor type, C 0.833
Rxra retinoid X receptor alpha 0.828
Hbb-b1 hemoglobin, beta adult major chain 0.827
Id1 inhibitor of DNA binding 1 0.825
Il6st interleukin 6 signal transducer 0.825
Lck lymphocyte protein tyrosine kinase 0.808
Atf2 activating transcription factor 2 0.780
Hoxb3 homeobox B3 0.776
Arid1a AT rich interactive domain 1A (SWI-like) 0.774
Bcl2 B-cell leukemia/lymphoma 2 0.766
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.756
Gfi1b growth factor independent 1B 0.754
Neurod1 neurogenic differentiation 1 0.739
Axin1 axin 1 0.706
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.694
Meox2 mesenchyme homeobox 2 0.692
Runx1 runt related transcription factor 1 0.687
Tcf4 transcription factor 4 0.684
Smad7 MAD homolog 7 (Drosophila) 0.684
Hoxa5 homeobox A5 0.673
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.665
Irf9 interferon regulatory factor 9 0.664
Shh sonic hedgehog 0.659
Il2rg interleukin 2 receptor, gamma chain 0.657
Hba-a2 hemoglobin alpha, adult chain 2 0.655
Ctnnb1 catenin (cadherin associated protein), beta 1 0.654
Rbl2 retinoblastoma-like 2 0.653
Hoxb6 homeobox B6 0.635
Sox4 SRY-box containing gene 4 0.625
Fgfr2 fibroblast growth factor receptor 2 0.619
Smad6 MAD homolog 6 (Drosophila) 0.617
Adam17 a disintegrin and metallopeptidase domain 17 0.602
Notch2 Notch gene homolog 2 (Drosophila) 0.590
Epas1 endothelial PAS domain protein 1 0.588
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.582
Plac1 placental specific protein 1 0.574
Axl AXL receptor tyrosine kinase 0.570
Hoxd1 homeobox D1 0.558
Tgfb2 transforming growth factor, beta 2 0.553
Tgfb1 transforming growth factor, beta 1 0.550
Mll5 myeloid/lymphoid or mixed-lineage leukemia 5 0.537
Hand2 heart and neural crest derivatives expressed transcript 2 0.523
Gpr50 G-protein-coupled receptor 50 0.523
Smad3 MAD homolog 3 (Drosophila) 0.522
Tcirg1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3 0.519
Tcf3 transcription factor 3 0.510
Trim30a tripartite motif-containing 30A 0.509
Hoxb8 homeobox B8 0.504
Id3 inhibitor of DNA binding 3 0.499
Vhl von Hippel-Lindau tumor suppressor 0.498
Stat5b signal transducer and activator of transcription 5B 0.486
Hoxb4 homeobox B4 0.469
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.461
Crebbp CREB binding protein 0.461
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.451
Plcg1 phospholipase C, gamma 1 0.439
Shox2 short stature homeobox 2 0.439
Nfe2 nuclear factor, erythroid derived 2 0.437
Klf1 Kruppel-like factor 1 (erythroid) 0.435
Egln1 EGL nine homolog 1 (C. elegans) 0.433
Zfpm2 zinc finger protein, multitype 2 0.433
Prf1 perforin 1 (pore forming protein) 0.430
Sox10 SRY-box containing gene 10 0.430
Klf3 Kruppel-like factor 3 (basic) 0.429
Ncoa6 nuclear receptor coactivator 6 0.426
Ptch2 patched homolog 2 0.423
Uba7 ubiquitin-like modifier activating enzyme 7 0.422
Hoxb5 homeobox B5 0.421
Acvrl1 activin A receptor, type II-like 1 0.419
Gja1 gap junction protein, alpha 1 0.415
Neurog1 neurogenin 1 0.413
Socs1 suppressor of cytokine signaling 1 0.410
Spnb2 spectrin beta 2 0.397
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.392
Mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.390
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
alas2 aminolevulinate, delta-, synthetase 2 0.987
pitx2 paired-like homeodomain transcription factor 2 0.978
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.947
tbx5a T-box 5a 0.874
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.838
LOC566708 FL cytokine receptor-like 0.835
hbae3 hemoglobin alpha embryonic-3 0.779
tfr1a transferrin receptor 1a 0.726
plcg1 phospholipase C, gamma 1 0.698
isl1 islet1 0.607
tal1 T-cell acute lymphocytic leukemia 1 0.503
gata1a GATA binding protein 1a 0.493
klf4 Kruppel-like factor 4 0.457
spns2 spinster homolog 2 (Drosophila) 0.456
hoxc6a homeo box C6a 0.443
gfi1.1 growth factor independent 1.1 0.432
epor erythropoietin receptor 0.389
cpox coproporphyrinogen oxidase 0.372
pax2a paired box gene 2a 0.320
hbbe3 hemoglobin beta embryonic-3 0.307
rpl23a ribosomal protein L23a 0.300
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.293
gata6 GATA-binding protein 6 0.276
vent ventral expressed homeobox 0.267
hbbe1.1 hemoglobin beta embryonic-1.1 0.252
myl7 myosin, light polypeptide 7, regulatory 0.214
myca myelocytomatosis oncogene a 0.212
rxrga retinoid x receptor, gamma a 0.198
dlc deltaC 0.194
gapdh glyceraldehyde-3-phosphate dehydrogenase 0.192
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.187
hnf1ba HNF1 homeobox Ba 0.181
urod uroporphyrinogen decarboxylase 0.181
mll4b myeloid/lymphoid or mixed-lineage leukemia 4b 0.178
gpia glucose phosphate isomerase a 0.174
si:dkeyp-66d7.2 si:dkeyp-66d7.2 0.159
anxa1b annexin A1b 0.156
trim33 tripartite motif-containing 33 0.154
f2r coagulation factor II (thrombin) receptor 0.151
cbfb core-binding factor, beta subunit 0.151
mafl v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L 0.147
isl2a islet2a 0.145
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.139
bmp2b bone morphogenetic protein 2b 0.138
kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.130
cahz carbonic anhydrase 0.130
acvr2b activin receptor IIb 0.124
hbaa1 hemoglobin alpha adult-1 0.124
sptb spectrin, beta, erythrocytic 0.122
LOC100151531 zinc finger protein Gfi-1b-like 0.119
spaw southpaw 0.119
prdm1a PR domain containing 1a, with ZNF domain 0.114
ca8 carbonic anhydrase VIII 0.114
rpl11 ribosomal protein L11 0.113
drl draculin 0.109
bcl2l1 bcl2-like 1 0.107
gata3 GATA-binding protein 3 0.105
sox7 SRY-box containing gene 7 0.104
jag2 jagged 2 0.104
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.102
si:dkeyp-22b2.3 si:dkeyp-22b2.3 0.099
hdr hematopoietic death receptor 0.098
tspo translocator protein 0.096
hoxd4a homeo box D4a 0.096
atoh1a atonal homolog 1a 0.095
dld deltaD 0.095
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.094
atoh1b atonal homolog 1b 0.094
pax3a paired box gene 3a 0.091
cebp1 CCAAT/enhancer binding protein (C/EBP) 1 0.091
mpx myeloid-specific peroxidase 0.091
her1 hairy-related 1 0.091
lft2 lefty2 0.087
foxi2 forkhead box I2 0.087
nt5c2l1 5'-nucleotidase, cytosolic II, like 1 0.086
ppox protoporphyrinogen oxidase 0.086
csf3r colony stimulating factor 3 receptor (granulocyte) 0.085
hbbe2 hemoglobin beta embryonic-2 0.084
neurod6b neurogenic differentiation 6b 0.083
pycard PYD and CARD domain containing 0.082
tfe3b transcription factor binding to IGHM enhancer 3b 0.082
mstnb myostatin b 0.081
lhx1a LIM homeobox 1a 0.081
eef1b2 eukaryotic translation elongation factor 1 beta 2 0.081
bnip3lb BCL2/adenovirus E1B interacting protein 3-like b 0.080
znfl2a zinc finger-like gene 2a 0.080
zgc:77702 zgc:77702 0.080
aco1 aconitase 1, soluble 0.079
faua Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a 0.078
pdcd2 programmed cell death 2 0.077
rpl13a ribosomal protein L13a 0.077
ccnd1 cyclin D1 0.076
zgc:66433 zgc:66433 0.076
gata2a GATA-binding protein 2a 0.076
perp PERP, TP53 apoptosis effector 0.075
rpl38 ribosomal protein L38 0.074
rps18 ribosomal protein S18 0.074
rps12 ribosomal protein S12 0.074
matr3l matrin 3-like 0.074
ephb4b eph receptor B4b 0.072
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
SMAD2 SMAD family member 2 0.991
TAL1 T-cell acute lymphocytic leukemia 1 0.989
TP53 tumor protein p53 0.928
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.925
RPS10 ribosomal protein S10 0.820
KAT2B K(lysine) acetyltransferase 2B 0.682
SMAD7 SMAD family member 7 0.641
RUNX1 runt-related transcription factor 1 0.629
DDIT3 DNA-damage-inducible transcript 3 0.596
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.569
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.566
PGK1 phosphoglycerate kinase 1 0.545
SP1 Sp1 transcription factor 0.528
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.482
SMAD3 SMAD family member 3 0.479
CREBBP CREB binding protein 0.455
NCOA6 nuclear receptor coactivator 6 0.422
XIAP X-linked inhibitor of apoptosis 0.410
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.379
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.368
RPS16 ribosomal protein S16 0.345
S100A10 S100 calcium binding protein A10 0.316
RPS11 ribosomal protein S11 0.314
TCF12 transcription factor 12 0.310
HOXB5 homeobox B5 0.299
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.297
SYK spleen tyrosine kinase 0.292
TKT transketolase 0.287
CCND1 cyclin D1 0.280
BCL2L1 BCL2-like 1 0.278
JUN jun proto-oncogene 0.273
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.254
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.253
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.246
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.241
UBASH3B ubiquitin associated and SH3 domain containing B 0.234
FKBP1A FK506 binding protein 1A, 12kDa 0.233
CFLAR CASP8 and FADD-like apoptosis regulator 0.226
NRP1 neuropilin 1 0.214
HOXA5 homeobox A5 0.212
BCL2 B-cell CLL/lymphoma 2 0.209
ANXA1 annexin A1 0.206
APAF1 apoptotic peptidase activating factor 1 0.203
MSN moesin 0.194
GATA2 GATA binding protein 2 0.178
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.159
BMPR1A bone morphogenetic protein receptor, type IA 0.152
RPS3 ribosomal protein S3 0.142
RPS15A ribosomal protein S15a 0.142
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.142
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.135
SLC4A1 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) 0.135
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.133
BMP2 bone morphogenetic protein 2 0.133
EP300 E1A binding protein p300 0.129
HBG2 hemoglobin, gamma G 0.129
RPL5 ribosomal protein L5 0.124
GSK3B glycogen synthase kinase 3 beta 0.121
HOXA10 homeobox A10 0.121
GAS6 growth arrest-specific 6 0.117
NCOA1 nuclear receptor coactivator 1 0.114
NCOR2 nuclear receptor corepressor 2 0.111
TGFB1 transforming growth factor, beta 1 0.108
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.104
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.104
MAPK8 mitogen-activated protein kinase 8 0.103
NFIL3 nuclear factor, interleukin 3 regulated 0.102
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.100
RPS5 ribosomal protein S5 0.099
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.099
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.099
RPS15 ribosomal protein S15 0.096
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.096
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.095
ARID4B AT rich interactive domain 4B (RBP1-like) 0.093
QKI quaking homolog, KH domain RNA binding (mouse) 0.092
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.091
BAG3 BCL2-associated athanogene 3 0.090
GATA4 GATA binding protein 4 0.090
APH1A anterior pharynx defective 1 homolog A (C. elegans) 0.089
RBBP4 retinoblastoma binding protein 4 0.085
GAS7 growth arrest-specific 7 0.085
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.084
NMI N-myc (and STAT) interactor 0.084
RPS2 ribosomal protein S2 0.081
GYPB glycophorin B (MNS blood group) 0.080
SPTB spectrin, beta, erythrocytic 0.080
CAPG capping protein (actin filament), gelsolin-like 0.077
SIRT1 sirtuin 1 0.075
RPLP2 ribosomal protein, large, P2 0.074
GHR growth hormone receptor 0.074
RHAG Rh-associated glycoprotein 0.072
INSR insulin receptor 0.070
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.068
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.068
SMAD1 SMAD family member 1 0.067
ANK1 ankyrin 1, erythrocytic 0.067
RPLP1 ribosomal protein, large, P1 0.064
CUX1 cut-like homeobox 1 0.064
HOXA9 homeobox A9 0.062
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Hbb hemoglobin, beta 0.121
Alas2 aminolevulinate, delta-, synthase 2 0.112
Hba-a2 hemoglobin alpha, adult chain 2 0.100
Elk3 ELK3, ETS-domain protein 0.096
LOC100134871 beta globin minor gene 0.092
Ptprc protein tyrosine phosphatase, receptor type, C 0.077
LOC287167 globin, alpha 0.052
Adam17 ADAM metallopeptidase domain 17 0.045
LOC689064 beta-globin 0.037
Hbb-b1 hemoglobin, beta adult major chain 0.028
Jak1 Janus kinase 1 0.016
Tgfbr3 transforming growth factor, beta receptor III 0.012
Casp3 caspase 3 0.012
Iqgap1 IQ motif containing GTPase activating protein 1 0.012
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism