IMP

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Homo sapiens

27 genes annotated in human

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regulation of muscle organ development

GO:0048634

Any process that modulates the frequency, rate or extent of muscle development.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of muscle organ development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of muscle organ development" (in gray)

Name	Description	Probability	Func Analog Organism
FGFR2	fibroblast growth factor receptor 2	0.999	Mouse
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.995
NOTCH1	notch 1	0.993
EP300	E1A binding protein p300	0.991
JAG1	jagged 1	0.989
FGF1	fibroblast growth factor 1 (acidic)	0.953	Human
NCOA3	nuclear receptor coactivator 3	0.929
HDAC4	histone deacetylase 4	0.926	Mouse
CREBBP	CREB binding protein	0.906
ESR1	estrogen receptor 1	0.868
SMAD7	SMAD family member 7	0.842	Fly
HDAC3	histone deacetylase 3	0.798
SMAD1	SMAD family member 1	0.798
AR	androgen receptor	0.710
FSTL1	follistatin-like 1	0.667
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.594	Rat
SIRT1	sirtuin 1	0.580
MEF2C	myocyte enhancer factor 2C	0.571
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.524
FGFR1	fibroblast growth factor receptor 1	0.519	Mouse
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.486
FGF10	fibroblast growth factor 10	0.463	Human
AHR	aryl hydrocarbon receptor	0.449
MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	0.445
JUN	jun proto-oncogene	0.409
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.372
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.335
NCOR2	nuclear receptor corepressor 2	0.329
NOTCH3	notch 3	0.316	Human
RB1	retinoblastoma 1	0.300
TBX5	T-box 5	0.283
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.277
NCOR1	nuclear receptor corepressor 1	0.272
TJP1	tight junction protein 1 (zona occludens 1)	0.266
SETD8	SET domain containing (lysine methyltransferase) 8	0.256
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.255
TTN	titin	0.245
MEF2A	myocyte enhancer factor 2A	0.235	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.232	Mouse
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.216
YAP1	Yes-associated protein 1	0.213
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.188
NCOA1	nuclear receptor coactivator 1	0.174
KAT2B	K(lysine) acetyltransferase 2B	0.172
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.169
IGF2	insulin-like growth factor 2 (somatomedin A)	0.168
FGF2	fibroblast growth factor 2 (basic)	0.167
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.164
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.162
SMAD6	SMAD family member 6	0.160	Fly
AXIN1	axin 1	0.156
ARRDC3	arrestin domain containing 3	0.154
TGFB3	transforming growth factor, beta 3	0.153
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.147
TGFB1	transforming growth factor, beta 1	0.136
FGF8	fibroblast growth factor 8 (androgen-induced)	0.126
FZD1	frizzled homolog 1 (Drosophila)	0.125
TCF4	transcription factor 4	0.104
MAPK8	mitogen-activated protein kinase 8	0.096
SATB2	SATB homeobox 2	0.096
FBLN1	fibulin 1	0.095
ENG	endoglin	0.086
TGFBR1	transforming growth factor, beta receptor 1	0.085
BCL6	B-cell CLL/lymphoma 6	0.085
CNOT8	CCR4-NOT transcription complex, subunit 8	0.083
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.083
HDAC9	histone deacetylase 9	0.082	Mouse
DLL1	delta-like 1 (Drosophila)	0.081
ATF3	activating transcription factor 3	0.080
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.080
SMAD5	SMAD family member 5	0.079
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.079
CXCL11	chemokine (C-X-C motif) ligand 11	0.075
BMP7	bone morphogenetic protein 7	0.073	Fly
ZHX1	zinc fingers and homeoboxes 1	0.071
BMP2	bone morphogenetic protein 2	0.069
STK3	serine/threonine kinase 3	0.068
CLOCK	clock homolog (mouse)	0.067
GDF5	growth differentiation factor 5	0.066
ADAM12	ADAM metallopeptidase domain 12	0.066
SMAD4	SMAD family member 4	0.062
MAML1	mastermind-like 1 (Drosophila)	0.061
HIC1	hypermethylated in cancer 1	0.060
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.056
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.055	Mouse
NCOA2	nuclear receptor coactivator 2	0.052
MYOD1	myogenic differentiation 1	0.052
CDK2	cyclin-dependent kinase 2	0.052
MKL1	megakaryoblastic leukemia (translocation) 1	0.051	Human
GATA4	GATA binding protein 4	0.051	Mouse
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.050
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.049
TGFB2	transforming growth factor, beta 2	0.049	Human
RICTOR	RPTOR independent companion of MTOR, complex 2	0.048
DBP	D site of albumin promoter (albumin D-box) binding protein	0.047
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.046
PARVA	parvin, alpha	0.045
INO80B	INO80 complex subunit B	0.045
NOG	noggin	0.044	Mouse
COL1A1	collagen, type I, alpha 1	0.043
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.042
JAG2	jagged 2	0.042
HIST1H1E	histone cluster 1, H1e	0.042
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.042
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.041
DUSP1	dual specificity phosphatase 1	0.041
PNRC1	proline-rich nuclear receptor coactivator 1	0.041
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.040
C5orf41	chromosome 5 open reading frame 41	0.040
TP53	tumor protein p53	0.039	Human
SMAD3	SMAD family member 3	0.039	Mouse
FGFR3	fibroblast growth factor receptor 3	0.039
HDAC1	histone deacetylase 1	0.038
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.038
BMP4	bone morphogenetic protein 4	0.038
CABLES1	Cdk5 and Abl enzyme substrate 1	0.038
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.037
FGF3	fibroblast growth factor 3	0.036
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.035
BMPR1A	bone morphogenetic protein receptor, type IA	0.035	Fly
ATN1	atrophin 1	0.035
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.035	Human Mouse
DPP4	dipeptidyl-peptidase 4	0.035
GABARAP	GABA(A) receptor-associated protein	0.035
APP	amyloid beta (A4) precursor protein	0.034
PTEN	phosphatase and tensin homolog	0.034
WWOX	WW domain containing oxidoreductase	0.034
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.034
FGF7	fibroblast growth factor 7	0.033	Human
GSK3B	glycogen synthase kinase 3 beta	0.033
PHF10	PHD finger protein 10	0.033
CCNA2	cyclin A2	0.032
THBS1	thrombospondin 1	0.032
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.032
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.031
HOXC8	homeobox C8	0.031
FZD8	frizzled homolog 8 (Drosophila)	0.031
LBX1	ladybird homeobox 1	0.031
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.030
NOTCH2	notch 2	0.029	Human
RBM4	RNA binding motif protein 4	0.029
CDK1	cyclin-dependent kinase 1	0.029	Rat
FOXF2	forkhead box F2	0.029
HDAC6	histone deacetylase 6	0.028
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.028
FGF4	fibroblast growth factor 4	0.028	Human
AMOTL1	angiomotin like 1	0.028
PLCG1	phospholipase C, gamma 1	0.028
FOXF1	forkhead box F1	0.028
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.027
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.027
EGLN3	egl nine homolog 3 (C. elegans)	0.027
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.027
SMAD2	SMAD family member 2	0.026
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.026
KLF13	Kruppel-like factor 13	0.026
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.025
KRT5	keratin 5	0.025
JUND	jun D proto-oncogene	0.025
WWTR1	WW domain containing transcription regulator 1	0.024
WNT1	wingless-type MMTV integration site family, member 1	0.024	Human
TNNI1	troponin I type 1 (skeletal, slow)	0.024
PRKCA	protein kinase C, alpha	0.024
GAS1	growth arrest-specific 1	0.024
HPCAL4	hippocalcin like 4	0.024
FRS2	fibroblast growth factor receptor substrate 2	0.024
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.024
BTF3	basic transcription factor 3	0.024
CTGF	connective tissue growth factor	0.023
NEB	nebulin	0.023
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.023
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.023
SOX7	SRY (sex determining region Y)-box 7	0.023
EGLN1	egl nine homolog 1 (C. elegans)	0.023
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.022
HSPG2	heparan sulfate proteoglycan 2	0.022
JUP	junction plakoglobin	0.022
FOXO1	forkhead box O1	0.022
FST	follistatin	0.022
E2F1	E2F transcription factor 1	0.022
TJP2	tight junction protein 2 (zona occludens 2)	0.021
SIM2	single-minded homolog 2 (Drosophila)	0.021
HIST1H3B	histone cluster 1, H3b	0.021
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.021
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.021
HMGA2	high mobility group AT-hook 2	0.020
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.020	Mouse
SFRP1	secreted frizzled-related protein 1	0.020
INVS	inversin	0.020
BCL2	B-cell CLL/lymphoma 2	0.020	Mouse
TTR	transthyretin	0.020
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.020
COL2A1	collagen, type II, alpha 1	0.020
HAND2	heart and neural crest derivatives expressed 2	0.020
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.020
FZD7	frizzled homolog 7 (Drosophila)	0.019
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.019	Human
TF	transferrin	0.019
CKS2	CDC28 protein kinase regulatory subunit 2	0.019
CCNE1	cyclin E1	0.019
NEURL4	neuralized homolog 4 (Drosophila)	0.019
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.019
EYA1	eyes absent homolog 1 (Drosophila)	0.018
ATXN1L	ataxin 1-like	0.018
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.018
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.018
GATA5	GATA binding protein 5	0.018
COASY	CoA synthase	0.018
FOXL1	forkhead box L1	0.018
GLIS2	GLIS family zinc finger 2	0.018
GJD3	gap junction protein, delta 3, 31.9kDa	0.018
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.018
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.018
WNT11	wingless-type MMTV integration site family, member 11	0.018
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.017
RBM4B	RNA binding motif protein 4B	0.017
SIX2	SIX homeobox 2	0.017
EPHA3	EPH receptor A3	0.017
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.017
FUNDC2	FUN14 domain containing 2	0.017
SLIT2	slit homolog 2 (Drosophila)	0.017
TCAP	titin-cap (telethonin)	0.017
PLCE1	phospholipase C, epsilon 1	0.017
CNOT7	CCR4-NOT transcription complex, subunit 7	0.016
RREB1	ras responsive element binding protein 1	0.016
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.016
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.016
AURKA	aurora kinase A	0.016
MAPT	microtubule-associated protein tau	0.016
PARVB	parvin, beta	0.016
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.016
GDNF	glial cell derived neurotrophic factor	0.016
HES1	hairy and enhancer of split 1, (Drosophila)	0.016
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.016
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.016
ITGB1BP3	integrin beta 1 binding protein 3	0.016
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.016
FOXC1	forkhead box C1	0.015
RBMS3	RNA binding motif, single stranded interacting protein 3	0.015
BTG2	BTG family, member 2	0.015	Human
GABPB2	GA binding protein transcription factor, beta subunit 2	0.015
SS18	synovial sarcoma translocation, chromosome 18	0.015
TBX1	T-box 1	0.015	Human
UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats	0.015
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.015
TBC1D10A	TBC1 domain family, member 10A	0.015
NRP1	neuropilin 1	0.015
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.015
IQGAP1	IQ motif containing GTPase activating protein 1	0.015
SLIT3	slit homolog 3 (Drosophila)	0.015
FERMT2	fermitin family member 2	0.015
TGFBR3	transforming growth factor, beta receptor III	0.014
RBPMS	RNA binding protein with multiple splicing	0.014
NOV	nephroblastoma overexpressed gene	0.014
KLF5	Kruppel-like factor 5 (intestinal)	0.014
BDNF	brain-derived neurotrophic factor	0.014
INHBB	inhibin, beta B	0.014
VEZF1	vascular endothelial zinc finger 1	0.014
JMY	junction mediating and regulatory protein, p53 cofactor	0.014
PRRX2	paired related homeobox 2	0.014
MBNL1	muscleblind-like (Drosophila)	0.014
YY1	YY1 transcription factor	0.014
FN1	fibronectin 1	0.014
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.014	Human
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.014
NPAS1	neuronal PAS domain protein 1	0.014
DDR2	discoidin domain receptor tyrosine kinase 2	0.014
NPAS2	neuronal PAS domain protein 2	0.014
ALX4	ALX homeobox 4	0.014
WNT3	wingless-type MMTV integration site family, member 3	0.014
DHH	desert hedgehog	0.014
GSC	goosecoid homeobox	0.013
DLL4	delta-like 4 (Drosophila)	0.013
ZNF148	zinc finger protein 148	0.013
ECEL1	endothelin converting enzyme-like 1	0.013
HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14	0.013
BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	0.013
BCL2L1	BCL2-like 1	0.013
WNT10A	wingless-type MMTV integration site family, member 10A	0.013
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.013
PIAS4	protein inhibitor of activated STAT, 4	0.013
TP73	tumor protein p73	0.013
TNS4	tensin 4	0.013
TRO	trophinin	0.013
KRT6C	keratin 6C	0.013
DLX4	distal-less homeobox 4	0.013
TLX2	T-cell leukemia homeobox 2	0.013
EPHA4	EPH receptor A4	0.013
ADSS	adenylosuccinate synthase	0.013
HOXD9	homeobox D9	0.012
BHLHE23	basic helix-loop-helix family, member e23	0.012
COL13A1	collagen, type XIII, alpha 1	0.012
FILIP1L	filamin A interacting protein 1-like	0.012
GATAD2B	GATA zinc finger domain containing 2B	0.012
TRIM63	tripartite motif containing 63	0.012
IGF1	insulin-like growth factor 1 (somatomedin C)	0.012
EYA2	eyes absent homolog 2 (Drosophila)	0.012
TNC	tenascin C	0.012
ACAN	aggrecan	0.012
POU4F3	POU class 4 homeobox 3	0.012
MBD2	methyl-CpG binding domain protein 2	0.012
NOTCH2NL	notch 2 N-terminal like	0.012
QKI	quaking homolog, KH domain RNA binding (mouse)	0.012
PPARA	peroxisome proliferator-activated receptor alpha	0.012
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.012
PDE10A	phosphodiesterase 10A	0.012
ACVR2B	activin A receptor, type IIB	0.012
A4GALT	alpha 1,4-galactosyltransferase	0.012
MRC2	mannose receptor, C type 2	0.012
DCN	decorin	0.012
PDX1	pancreatic and duodenal homeobox 1	0.012
SOX9	SRY (sex determining region Y)-box 9	0.012	Mouse
SIX1	SIX homeobox 1	0.012	Mouse
CRLF1	cytokine receptor-like factor 1	0.012
SFRP5	secreted frizzled-related protein 5	0.012
TBX2	T-box 2	0.011
TBL1X	transducin (beta)-like 1X-linked	0.011
TWIST2	twist homolog 2 (Drosophila)	0.011
HOXD10	homeobox D10	0.011
NEUROG1	neurogenin 1	0.011
FGF6	fibroblast growth factor 6	0.011	Human
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.011
LHX5	LIM homeobox 5	0.011
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.011
SOX11	SRY (sex determining region Y)-box 11	0.011
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.011
FGF18	fibroblast growth factor 18	0.011	Human
PAX8	paired box 8	0.011
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.011
MSX1	msh homeobox 1	0.011
GBX2	gastrulation brain homeobox 2	0.011
HDAC7	histone deacetylase 7	0.011
KLF9	Kruppel-like factor 9	0.011
PYY	peptide YY	0.011
PDGFC	platelet derived growth factor C	0.011
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.011
VEGFC	vascular endothelial growth factor C	0.011
SWAP70	SWAP switching B-cell complex 70kDa subunit	0.011
CXCR3	chemokine (C-X-C motif) receptor 3	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011	Rat
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.011
FKBP8	FK506 binding protein 8, 38kDa	0.011
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.011
CNN1	calponin 1, basic, smooth muscle	0.011
GPC4	glypican 4	0.011
ASB9	ankyrin repeat and SOCS box containing 9	0.011
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.011
SOX2	SRY (sex determining region Y)-box 2	0.011
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.011
IRX4	iroquois homeobox 4	0.011
BCAM	basal cell adhesion molecule (Lutheran blood group)	0.011
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.011
BEND5	BEN domain containing 5	0.011
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.011
ASB13	ankyrin repeat and SOCS box containing 13	0.010
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.010
PTCH1	patched 1	0.010
PITX2	paired-like homeodomain 2	0.010
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.010
MAGEA2	melanoma antigen family A, 2	0.010
DLG2	discs, large homolog 2 (Drosophila)	0.010
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.010
BNC1	basonuclin 1	0.010
UTF1	undifferentiated embryonic cell transcription factor 1	0.010
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.010
LRRK2	leucine-rich repeat kinase 2	0.010
PCDH7	protocadherin 7	0.010
RAX	retina and anterior neural fold homeobox	0.010
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.010
LMX1B	LIM homeobox transcription factor 1, beta	0.010
GOLT1B	golgi transport 1B	0.010
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.010
PRKG1	protein kinase, cGMP-dependent, type I	0.010
CLIC4	chloride intracellular channel 4	0.010
ERAS	ES cell expressed Ras	0.010
NOSTRIN	nitric oxide synthase trafficker	0.010
CDH5	cadherin 5, type 2 (vascular endothelium)	0.010
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.010