IMP

Process View

Homo sapiens

25 genes annotated in human

positive regulation of transcription factor import into nucleus

Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of transcription factor import into nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of transcription factor import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
SMAD1	SMAD family member 1	0.994	Human
SMAD3	SMAD family member 3	0.992
IL1R1	interleukin 1 receptor, type I	0.890
SMAD4	SMAD family member 4	0.887	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.829
BTRC	beta-transducin repeat containing	0.811	Fly
SMAD5	SMAD family member 5	0.752	Human
CCR5	chemokine (C-C motif) receptor 5	0.670
CCL4	chemokine (C-C motif) ligand 4	0.643	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.593
MYD88	myeloid differentiation primary response gene (88)	0.585
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.484
SH2D4A	SH2 domain containing 4A	0.457
FLNB	filamin B, beta	0.434	Human
PSEN1	presenilin 1	0.418
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.372
SMAD2	SMAD family member 2	0.372	Human
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.360
CXCL2	chemokine (C-X-C motif) ligand 2	0.348
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.298
FLNA	filamin A, alpha	0.292
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.267
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.238
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.234
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.225
IL8	interleukin 8	0.207
RNF31	ring finger protein 31	0.206
MAVS	mitochondrial antiviral signaling protein	0.205
CUL1	cullin 1	0.197
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.178
IL1B	interleukin 1, beta	0.177
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.174
CCL2	chemokine (C-C motif) ligand 2	0.151	Human
KPNB1	karyopherin (importin) beta 1	0.145	Fly
CCR1	chemokine (C-C motif) receptor 1	0.132
ZNF84	zinc finger protein 84	0.129
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.127
FBXW11	F-box and WD repeat domain containing 11	0.120	Fly
CCL8	chemokine (C-C motif) ligand 8	0.114	Human
YAP1	Yes-associated protein 1	0.111
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.102
LY96	lymphocyte antigen 96	0.101
TRAF1	TNF receptor-associated factor 1	0.100
IDE	insulin-degrading enzyme	0.098
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.096
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.096
TNF	tumor necrosis factor	0.091
CD83	CD83 molecule	0.088
IL1R2	interleukin 1 receptor, type II	0.087
PLAUR	plasminogen activator, urokinase receptor	0.084
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.082
HIPK3	homeodomain interacting protein kinase 3	0.082
IRF2	interferon regulatory factor 2	0.080
DSG2	desmoglein 2	0.078
CFLAR	CASP8 and FADD-like apoptosis regulator	0.076
CXCL10	chemokine (C-X-C motif) ligand 10	0.075
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.074
WIPF1	WAS/WASL interacting protein family, member 1	0.071
JUP	junction plakoglobin	0.064
BBS10	Bardet-Biedl syndrome 10	0.056
SKP1	S-phase kinase-associated protein 1	0.056
CXCL11	chemokine (C-X-C motif) ligand 11	0.055
ICAM1	intercellular adhesion molecule 1	0.055
APC	adenomatous polyposis coli	0.054
WASL	Wiskott-Aldrich syndrome-like	0.053
CBX5	chromobox homolog 5	0.052
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.051	Human
BIRC3	baculoviral IAP repeat containing 3	0.050
ACTN1	actinin, alpha 1	0.050
RIPK2	receptor-interacting serine-threonine kinase 2	0.049
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.048
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.048
RACGAP1	Rac GTPase activating protein 1	0.047
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.047
SKIL	SKI-like oncogene	0.047
MBOAT7	membrane bound O-acyltransferase domain containing 7	0.046
HOXA9	homeobox A9	0.046
IL6	interleukin 6 (interferon, beta 2)	0.044
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.044
MYH9	myosin, heavy chain 9, non-muscle	0.044
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.044
RBM10	RNA binding motif protein 10	0.044
CXCL9	chemokine (C-X-C motif) ligand 9	0.044
SNAI1	snail homolog 1 (Drosophila)	0.043
TREM1	triggering receptor expressed on myeloid cells 1	0.043
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.042
MAPK6	mitogen-activated protein kinase 6	0.041
ZNF432	zinc finger protein 432	0.041
SPRR2A	small proline-rich protein 2A	0.041
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.039
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.039
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.038
CUL4A	cullin 4A	0.038
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.038
CCL20	chemokine (C-C motif) ligand 20	0.037	Human
TRIM21	tripartite motif containing 21	0.037
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.036
CCR7	chemokine (C-C motif) receptor 7	0.036
NLK	nemo-like kinase	0.035
TMEM173	transmembrane protein 173	0.035
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.034
MDC1	mediator of DNA-damage checkpoint 1	0.034
BCL2A1	BCL2-related protein A1	0.033
CXXC5	CXXC finger protein 5	0.033
CCL11	chemokine (C-C motif) ligand 11	0.032	Human
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.032
CYLD	cylindromatosis (turban tumor syndrome)	0.031
WEE1	WEE1 homolog (S. pombe)	0.031
TLR2	toll-like receptor 2	0.031
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.031
CXCL13	chemokine (C-X-C motif) ligand 13	0.030
PSEN2	presenilin 2 (Alzheimer disease 4)	0.030
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.030
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.030
XIRP1	xin actin-binding repeat containing 1	0.030
ATF7IP	activating transcription factor 7 interacting protein	0.029
CTNND1	catenin (cadherin-associated protein), delta 1	0.029
CCL3	chemokine (C-C motif) ligand 3	0.029	Human
CCR4	chemokine (C-C motif) receptor 4	0.028
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.027
CXCL5	chemokine (C-X-C motif) ligand 5	0.027
CCL13	chemokine (C-C motif) ligand 13	0.027	Human
CCL22	chemokine (C-C motif) ligand 22	0.026	Human
ZNF569	zinc finger protein 569	0.026
CXCL3	chemokine (C-X-C motif) ligand 3	0.026
ZBED5	zinc finger, BED-type containing 5	0.026
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.025
CBX1	chromobox homolog 1	0.025
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.025
LMNA	lamin A/C	0.025
IL10	interleukin 10	0.025
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.024
TRIM33	tripartite motif containing 33	0.024	Human
ZNF585A	zinc finger protein 585A	0.024
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.023
DPP4	dipeptidyl-peptidase 4	0.023
CUL2	cullin 2	0.022
SELE	selectin E	0.022
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.022
MAGEA11	melanoma antigen family A, 11	0.021
SFN	stratifin	0.021
IRAK1	interleukin-1 receptor-associated kinase 1	0.021
FBXL15	F-box and leucine-rich repeat protein 15	0.021
LMO4	LIM domain only 4	0.020
CCL19	chemokine (C-C motif) ligand 19	0.020
INHBA	inhibin, beta A	0.020
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.020
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.019
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.019
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.018
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.018
ATM	ataxia telangiectasia mutated	0.018
IFNG	interferon, gamma	0.018
SMAD9	SMAD family member 9	0.018	Human
VCAM1	vascular cell adhesion molecule 1	0.018
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.018
C3AR1	complement component 3a receptor 1	0.017
IL7R	interleukin 7 receptor	0.017
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.017
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.017
CNN2	calponin 2	0.017
TPM4	tropomyosin 4	0.017
PARP12	poly (ADP-ribose) polymerase family, member 12	0.017
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.017
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.016
GLIS2	GLIS family zinc finger 2	0.016
FHL1	four and a half LIM domains 1	0.016
PYDC2	pyrin domain containing 2	0.016
LAT	linker for activation of T cells	0.016
IRAK3	interleukin-1 receptor-associated kinase 3	0.016
FPR3	formyl peptide receptor 3	0.016
IFIH1	interferon induced with helicase C domain 1	0.016	Human
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.016
TFPI2	tissue factor pathway inhibitor 2	0.016
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.016
CH25H	cholesterol 25-hydroxylase	0.016
TRAF2	TNF receptor-associated factor 2	0.015
TGFBR1	transforming growth factor, beta receptor 1	0.015
KYNU	kynureninase	0.015
C1orf93	chromosome 1 open reading frame 93	0.015
CENPE	centromere protein E, 312kDa	0.015
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.015
C20orf20	chromosome 20 open reading frame 20	0.015
SMAD7	SMAD family member 7	0.015	Human
CARD11	caspase recruitment domain family, member 11	0.014
BTK	Bruton agammaglobulinemia tyrosine kinase	0.014
IL18RAP	interleukin 18 receptor accessory protein	0.014
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.014
ITGB7	integrin, beta 7	0.014
MYOZ1	myozenin 1	0.014
IL4R	interleukin 4 receptor	0.014
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.014	Human
RGS1	regulator of G-protein signaling 1	0.014
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.014
IFI44	interferon-induced protein 44	0.014
CCL7	chemokine (C-C motif) ligand 7	0.014	Human
TICAM2	toll-like receptor adaptor molecule 2	0.014
PBK	PDZ binding kinase	0.014
SHARPIN	SHANK-associated RH domain interactor	0.013
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.013
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.013
USP9X	ubiquitin specific peptidase 9, X-linked	0.013
FBLIM1	filamin binding LIM protein 1	0.013	Human
FHL3	four and a half LIM domains 3	0.013
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.013
EBI3	Epstein-Barr virus induced 3	0.013
ZNF211	zinc finger protein 211	0.013
PLEK	pleckstrin	0.013
TCF12	transcription factor 12	0.013
IRF7	interferon regulatory factor 7	0.013
KIF4A	kinesin family member 4A	0.013
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.013
PDLIM7	PDZ and LIM domain 7 (enigma)	0.013
WDR26	WD repeat domain 26	0.013
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.012
ZNF140	zinc finger protein 140	0.012	Human
AQP9	aquaporin 9	0.012
MKL2	MKL/myocardin-like 2	0.012
ZNF12	zinc finger protein 12	0.012
ZNF571	zinc finger protein 571	0.012
PIAS1	protein inhibitor of activated STAT, 1	0.012
PKP4	plakophilin 4	0.012
SH3BP2	SH3-domain binding protein 2	0.012
LAMP3	lysosomal-associated membrane protein 3	0.012
TNPO1	transportin 1	0.012
SCRIB	scribbled homolog (Drosophila)	0.012
IL1A	interleukin 1, alpha	0.012	Human
MEST	mesoderm specific transcript homolog (mouse)	0.012
TRIM63	tripartite motif containing 63	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.012
STAT4	signal transducer and activator of transcription 4	0.012
MSC	musculin	0.012
TRIM25	tripartite motif containing 25	0.012
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.012
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.011
IFI44L	interferon-induced protein 44-like	0.011
DDB1	damage-specific DNA binding protein 1, 127kDa	0.011
IL21R	interleukin 21 receptor	0.011
AR	androgen receptor	0.011
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.011
IRF4	interferon regulatory factor 4	0.011
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.011
PHF19	PHD finger protein 19	0.011
PTPRE	protein tyrosine phosphatase, receptor type, E	0.011
DSP	desmoplakin	0.011
IL2RG	interleukin 2 receptor, gamma	0.011
TFEC	transcription factor EC	0.011
CCL5	chemokine (C-C motif) ligand 5	0.011	Human
GPR109B	G protein-coupled receptor 109B	0.011
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.011
TNRC6A	trinucleotide repeat containing 6A	0.011
SRPK2	SRSF protein kinase 2	0.011
GFI1B	growth factor independent 1B transcription repressor	0.011
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.011
ARF6	ADP-ribosylation factor 6	0.011
ZNF529	zinc finger protein 529	0.011
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.010
FNBP1	formin binding protein 1	0.010
LASP1	LIM and SH3 protein 1	0.010
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.010
PTAFR	platelet-activating factor receptor	0.010
ZNF260	zinc finger protein 260	0.010
EDAR	ectodysplasin A receptor	0.010
DGCR14	DiGeorge syndrome critical region gene 14	0.010
TYMP	thymidine phosphorylase	0.010
PI3	peptidase inhibitor 3, skin-derived	0.010
ZMYM2	zinc finger, MYM-type 2	0.010
PTK2	PTK2 protein tyrosine kinase 2	0.010