IMP

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Homo sapiens

22 genes annotated in human

regulation of cytokine production involved in immune response

Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of cytokine production involved in immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of cytokine production involved in immune response" (in gray)

Name	Description	Probability	Func Analog Organism
TRAF1	TNF receptor-associated factor 1	0.989	Human
TRAF6	TNF receptor-associated factor 6	0.966
BIRC3	baculoviral IAP repeat containing 3	0.963
CD40	CD40 molecule, TNF receptor superfamily member 5	0.896
RIPK2	receptor-interacting serine-threonine kinase 2	0.891
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.890
TRADD	TNFRSF1A-associated via death domain	0.810
CCR5	chemokine (C-C motif) receptor 5	0.787
TRAF3	TNF receptor-associated factor 3	0.726	Human
CCL4	chemokine (C-C motif) ligand 4	0.708	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.698
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.626
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.563
PILRA	paired immunoglobin-like type 2 receptor alpha	0.497
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.492
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.487
IRAK2	interleukin-1 receptor-associated kinase 2	0.462
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.425
SQSTM1	sequestosome 1	0.424
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.410
SIGLEC7	sialic acid binding Ig-like lectin 7	0.297
A2M	alpha-2-macroglobulin	0.292
CD14	CD14 molecule	0.274
MYD88	myeloid differentiation primary response gene (88)	0.268
IL22RA1	interleukin 22 receptor, alpha 1	0.260
TRAF2	TNF receptor-associated factor 2	0.256
TGFB1	transforming growth factor, beta 1	0.250
TGIF1	TGFB-induced factor homeobox 1	0.226
TEK	TEK tyrosine kinase, endothelial	0.223	Mouse
CCL8	chemokine (C-C motif) ligand 8	0.219	Human
ALB	albumin	0.215
CCR7	chemokine (C-C motif) receptor 7	0.213
APOC1	apolipoprotein C-I	0.187
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.186
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.185	Human
BIRC2	baculoviral IAP repeat containing 2	0.180
CCR1	chemokine (C-C motif) receptor 1	0.176
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.175
SMAD3	SMAD family member 3	0.169
SOCS3	suppressor of cytokine signaling 3	0.158
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.152
IL10RA	interleukin 10 receptor, alpha	0.147
CXCL9	chemokine (C-X-C motif) ligand 9	0.145
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.139
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.135
IL10	interleukin 10	0.118
IL1B	interleukin 1, beta	0.117
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.112
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.109
HK3	hexokinase 3 (white cell)	0.098
CCL2	chemokine (C-C motif) ligand 2	0.096	Human
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.093	Human
TICAM2	toll-like receptor adaptor molecule 2	0.090
CCL7	chemokine (C-C motif) ligand 7	0.090	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.088
TYMP	thymidine phosphorylase	0.086
CALCOCO2	calcium binding and coiled-coil domain 2	0.082
CCL5	chemokine (C-C motif) ligand 5	0.082	Human
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.082
CCL22	chemokine (C-C motif) ligand 22	0.078	Human
TRAF5	TNF receptor-associated factor 5	0.067	Human
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.066
ANGPT1	angiopoietin 1	0.064	Mouse
IFNG	interferon, gamma	0.062
IL2RG	interleukin 2 receptor, gamma	0.062
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.061
IDE	insulin-degrading enzyme	0.060
CD80	CD80 molecule	0.058
TANK	TRAF family member-associated NFKB activator	0.057
ENG	endoglin	0.056
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.056	Human
BECN1	beclin 1, autophagy related	0.054
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.053	Mouse
TNF	tumor necrosis factor	0.049
IRF4	interferon regulatory factor 4	0.048
CCL13	chemokine (C-C motif) ligand 13	0.047	Human
CXCL10	chemokine (C-X-C motif) ligand 10	0.047
NUMBL	numb homolog (Drosophila)-like	0.045
HDAC9	histone deacetylase 9	0.044
IL22RA2	interleukin 22 receptor, alpha 2	0.044
APOC2	apolipoprotein C-II	0.042
IL7R	interleukin 7 receptor	0.042
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.041
CCR4	chemokine (C-C motif) receptor 4	0.041
NLRP3	NLR family, pyrin domain containing 3	0.039
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.038	Human
CD48	CD48 molecule	0.037
PLEK	pleckstrin	0.037
ZMYND11	zinc finger, MYND-type containing 11	0.036
EBI3	Epstein-Barr virus induced 3	0.036
CD86	CD86 molecule	0.035
NKG7	natural killer cell group 7 sequence	0.035
IL1RN	interleukin 1 receptor antagonist	0.033
FSTL1	follistatin-like 1	0.032
CXCL11	chemokine (C-X-C motif) ligand 11	0.030
CD40LG	CD40 ligand	0.030
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.028
CCR3	chemokine (C-C motif) receptor 3	0.028
CXCL13	chemokine (C-X-C motif) ligand 13	0.028
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.028
TIFA	TRAF-interacting protein with forkhead-associated domain	0.028
ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.028
TREM1	triggering receptor expressed on myeloid cells 1	0.027
IL2RA	interleukin 2 receptor, alpha	0.027
AQP9	aquaporin 9	0.027
MARCO	macrophage receptor with collagenous structure	0.026
HP	haptoglobin	0.026
CXCR4	chemokine (C-X-C motif) receptor 4	0.026
APOC3	apolipoprotein C-III	0.025
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.025
TGFB3	transforming growth factor, beta 3	0.025
CCL3	chemokine (C-C motif) ligand 3	0.024	Human
PCDH9	protocadherin 9	0.024
TLR2	toll-like receptor 2	0.024
CSF3	colony stimulating factor 3 (granulocyte)	0.024
AOAH	acyloxyacyl hydrolase (neutrophil)	0.024
PTAFR	platelet-activating factor receptor	0.024
CD83	CD83 molecule	0.023
CSF1	colony stimulating factor 1 (macrophage)	0.023
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.023	Human
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.022
DPP4	dipeptidyl-peptidase 4	0.022
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.022
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.021
BATF	basic leucine zipper transcription factor, ATF-like	0.021
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.020
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.020
C2	complement component 2	0.020
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.020
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.020
IL8	interleukin 8	0.020
IL2RB	interleukin 2 receptor, beta	0.019
CD300A	CD300a molecule	0.019
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.019
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.019
CA12	carbonic anhydrase XII	0.019
NCOR2	nuclear receptor corepressor 2	0.019
FPR3	formyl peptide receptor 3	0.019
CCL20	chemokine (C-C motif) ligand 20	0.019	Human
CHIT1	chitinase 1 (chitotriosidase)	0.019
BCL10	B-cell CLL/lymphoma 10	0.018
CCL19	chemokine (C-C motif) ligand 19	0.018	Human
FGA	fibrinogen alpha chain	0.018
IL6	interleukin 6 (interferon, beta 2)	0.018
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.018
ZC3H12A	zinc finger CCCH-type containing 12A	0.018
ICAM1	intercellular adhesion molecule 1	0.017
FCAR	Fc fragment of IgA, receptor for	0.017	Human
TGFBR1	transforming growth factor, beta receptor 1	0.017
BCL2A1	BCL2-related protein A1	0.017
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.017
VCAM1	vascular cell adhesion molecule 1	0.017
AIF1	allograft inflammatory factor 1	0.017
SIGLEC9	sialic acid binding Ig-like lectin 9	0.017
PPAP2B	phosphatidic acid phosphatase type 2B	0.017
CCL1	chemokine (C-C motif) ligand 1	0.016	Human
CCRL2	chemokine (C-C motif) receptor-like 2	0.016
TRAF3IP2	TRAF3 interacting protein 2	0.016
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.016
IGSF6	immunoglobulin superfamily, member 6	0.016
CCL11	chemokine (C-C motif) ligand 11	0.016	Human
SIRPB1	signal-regulatory protein beta 1	0.016
IL1R1	interleukin 1 receptor, type I	0.016
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.016
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.016
IL21R	interleukin 21 receptor	0.016
CMKLR1	chemokine-like receptor 1	0.016
HCK	hemopoietic cell kinase	0.016
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.016
LCAT	lecithin-cholesterol acyltransferase	0.015
RUNX3	runt-related transcription factor 3	0.015
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.015
FPR2	formyl peptide receptor 2	0.015
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.015
NRP2	neuropilin 2	0.015
C3AR1	complement component 3a receptor 1	0.015
LRP6	low density lipoprotein receptor-related protein 6	0.015
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.014
IL18RAP	interleukin 18 receptor accessory protein	0.014
IRF5	interferon regulatory factor 5	0.014
ADAMDEC1	ADAM-like, decysin 1	0.014
CCL17	chemokine (C-C motif) ligand 17	0.014	Human
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.014
IFNB1	interferon, beta 1, fibroblast	0.014
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.014	Human
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.014	Human
CXCL5	chemokine (C-X-C motif) ligand 5	0.014
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.013
SLAMF1	signaling lymphocytic activation molecule family member 1	0.013
CAV1	caveolin 1, caveolae protein, 22kDa	0.013
IFITM1	interferon induced transmembrane protein 1 (9-27)	0.013
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.013
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.013
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.013
LGALS9	lectin, galactoside-binding, soluble, 9	0.013	Human
NRP1	neuropilin 1	0.013
CFP	complement factor properdin	0.013
WDFY3	WD repeat and FYVE domain containing 3	0.013
SLAMF7	SLAM family member 7	0.012
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.012
APOBR	apolipoprotein B receptor	0.012
MSC	musculin	0.012
RETN	resistin	0.012
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.012
TNFRSF8	tumor necrosis factor receptor superfamily, member 8	0.012
GPR132	G protein-coupled receptor 132	0.012
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.012
IFI44	interferon-induced protein 44	0.012
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.012
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.012
CD209	CD209 molecule	0.012
IL24	interleukin 24	0.012	Human
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.012
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.012
C1QA	complement component 1, q subcomponent, A chain	0.012
RGS1	regulator of G-protein signaling 1	0.011
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.011
USP15	ubiquitin specific peptidase 15	0.011
IDO1	indoleamine 2,3-dioxygenase 1	0.011
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.011
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.011
CXCL2	chemokine (C-X-C motif) ligand 2	0.011
BIN2	bridging integrator 2	0.011
CD72	CD72 molecule	0.011
RGS16	regulator of G-protein signaling 16	0.011
GPR35	G protein-coupled receptor 35	0.011
IL4	interleukin 4	0.011
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.011
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.011
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.011
CD300C	CD300c molecule	0.010
CYBB	cytochrome b-245, beta polypeptide	0.010
SIGLEC5	sialic acid binding Ig-like lectin 5	0.010
IL13	interleukin 13	0.010
APP	amyloid beta (A4) precursor protein	0.010
CH25H	cholesterol 25-hydroxylase	0.010
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.010
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.010