IMP

Process View

Homo sapiens

36 genes annotated in human

carbohydrate catabolic process

The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "carbohydrate catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "carbohydrate catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
ALDOA	aldolase A, fructose-bisphosphate	0.992
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.988	Fly
ENO1	enolase 1, (alpha)	0.977	Mouse
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.943
TPI1	triosephosphate isomerase 1	0.929	Fly
PKM2	pyruvate kinase, muscle	0.922
GPI	glucose-6-phosphate isomerase	0.910	Mouse
LDHA	lactate dehydrogenase A	0.905
TKT	transketolase	0.887
NCOR2	nuclear receptor corepressor 2	0.790	Human
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.764
PGK1	phosphoglycerate kinase 1	0.753	Mouse
GLB1	galactosidase, beta 1	0.728	Rat
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.565
HK1	hexokinase 1	0.558	Yeast
CTSA	cathepsin A	0.497
ENO2	enolase 2 (gamma, neuronal)	0.427	Rat
NCOR1	nuclear receptor corepressor 1	0.421
EGFR	epidermal growth factor receptor	0.368
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.320
GRN	granulin	0.311
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.299
PGAM1	phosphoglycerate mutase 1 (brain)	0.284
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.281
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.258
GRB10	growth factor receptor-bound protein 10	0.236
PPARA	peroxisome proliferator-activated receptor alpha	0.231
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.220
IRS1	insulin receptor substrate 1	0.216
TALDO1	transaldolase 1	0.214
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.212
HNF4A	hepatocyte nuclear factor 4, alpha	0.186
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.179
NEU1	sialidase 1 (lysosomal sialidase)	0.176
GYS1	glycogen synthase 1 (muscle)	0.165
PFKL	phosphofructokinase, liver	0.161
BBS1	Bardet-Biedl syndrome 1	0.158
ITGB1BP3	integrin beta 1 binding protein 3	0.144
TPP1	tripeptidyl peptidase I	0.143
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.139
IGF2R	insulin-like growth factor 2 receptor	0.137
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.129	Human
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.112
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.111
RXRA	retinoid X receptor, alpha	0.104
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.100	Rat
ARID1A	AT rich interactive domain 1A (SWI-like)	0.096
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.094
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.086	Rat
RNPEP	arginyl aminopeptidase (aminopeptidase B)	0.077
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.072
TUBA4A	tubulin, alpha 4a	0.070
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.066
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.064
RARA	retinoic acid receptor, alpha	0.060
CAV1	caveolin 1, caveolae protein, 22kDa	0.057
CTSD	cathepsin D	0.056
PFKFB1	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	0.054	Human
ESR1	estrogen receptor 1	0.054
MAP4	microtubule-associated protein 4	0.053
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.052
GCKR	glucokinase (hexokinase 4) regulator	0.049
SMAD9	SMAD family member 9	0.048
CCND1	cyclin D1	0.048
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.048
DDB1	damage-specific DNA binding protein 1, 127kDa	0.047
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.045	Mouse
PGD	phosphogluconate dehydrogenase	0.044
IRS2	insulin receptor substrate 2	0.043
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.043
PTN	pleiotrophin	0.043
FBP2	fructose-1,6-bisphosphatase 2	0.042	Human
CAPRIN2	caprin family member 2	0.041
FAF1	Fas (TNFRSF6) associated factor 1	0.041
PLD3	phospholipase D family, member 3	0.041
CAPNS1	calpain, small subunit 1	0.040
LAMP1	lysosomal-associated membrane protein 1	0.040
HSPB1	heat shock 27kDa protein 1	0.039
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.038
GHR	growth hormone receptor	0.038
G6PD	glucose-6-phosphate dehydrogenase	0.037
BCL6	B-cell CLL/lymphoma 6	0.037
HR	hairless homolog (mouse)	0.036
PRKCSH	protein kinase C substrate 80K-H	0.036
AP2M1	adaptor-related protein complex 2, mu 1 subunit	0.036
PGR	progesterone receptor	0.036
MLX	MAX-like protein X	0.035
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.035	Yeast
ESRRG	estrogen-related receptor gamma	0.035
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.035
CLN3	ceroid-lipofuscinosis, neuronal 3	0.034
NCOA1	nuclear receptor coactivator 1	0.033
ALDOC	aldolase C, fructose-bisphosphate	0.033	Human Fly
VEGFA	vascular endothelial growth factor A	0.033
MEF2A	myocyte enhancer factor 2A	0.033
MAN2B1	mannosidase, alpha, class 2B, member 1	0.033
PFKP	phosphofructokinase, platelet	0.032	Human
ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b	0.031
EGLN3	egl nine homolog 3 (C. elegans)	0.031
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.031
BBS2	Bardet-Biedl syndrome 2	0.030
BSG	basigin (Ok blood group)	0.030
PPARG	peroxisome proliferator-activated receptor gamma	0.030	Human
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.030
ACACA	acetyl-CoA carboxylase alpha	0.028
PGM1	phosphoglucomutase 1	0.028
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.027
ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.027
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.026
BHLHE40	basic helix-loop-helix family, member e40	0.026
C16orf45	chromosome 16 open reading frame 45	0.026
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.026
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.026
CALR	calreticulin	0.026
EPOR	erythropoietin receptor	0.025
SLC25A1	solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1	0.025
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.025	Rat
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.025
PRDX1	peroxiredoxin 1	0.024
HDAC6	histone deacetylase 6	0.024
GK	glycerol kinase	0.024
IGF1R	insulin-like growth factor 1 receptor	0.024	Human
CDHR2	cadherin-related family member 2	0.023
BBS10	Bardet-Biedl syndrome 10	0.023
HLTF	helicase-like transcription factor	0.023
CAPG	capping protein (actin filament), gelsolin-like	0.023
STAT5B	signal transducer and activator of transcription 5B	0.022
HDAC3	histone deacetylase 3	0.022
GLA	galactosidase, alpha	0.022
KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.021
IL8	interleukin 8	0.021
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.021
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.021
PFKM	phosphofructokinase, muscle	0.021
C1orf85	chromosome 1 open reading frame 85	0.021
EGLN1	egl nine homolog 1 (C. elegans)	0.021
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.020
RUNX1	runt-related transcription factor 1	0.020
RPN2	ribophorin II	0.020
PSEN2	presenilin 2 (Alzheimer disease 4)	0.020
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.020	Human
FUCA1	fucosidase, alpha-L- 1, tissue	0.020
VDAC1	voltage-dependent anion channel 1	0.020
MAP2K1	mitogen-activated protein kinase kinase 1	0.019
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.019
LOC729020	rcRPE	0.019
MARCO	macrophage receptor with collagenous structure	0.019
OSGEPL1	O-sialoglycoprotein endopeptidase-like 1	0.019
GNS	glucosamine (N-acetyl)-6-sulfatase	0.019
TF	transferrin	0.019
MBL2	mannose-binding lectin (protein C) 2, soluble	0.019
GAPDHS	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.018	Fly
PGAM2	phosphoglycerate mutase 2 (muscle)	0.018
NUCB1	nucleobindin 1	0.018
TM9SF1	transmembrane 9 superfamily member 1	0.018
FUCA2	fucosidase, alpha-L- 2, plasma	0.018
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.018
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.018	Yeast
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.018
GPAA1	glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)	0.017
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.017
HDAC4	histone deacetylase 4	0.017	Mouse
MPV17	MpV17 mitochondrial inner membrane protein	0.017
ADM	adrenomedullin	0.017
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.017
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.017
IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.017
GLT25D1	glycosyltransferase 25 domain containing 1	0.017
HEXA	hexosaminidase A (alpha polypeptide)	0.017
CHD9	chromodomain helicase DNA binding protein 9	0.017
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.017	Yeast
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.017
RPL3L	ribosomal protein L3-like	0.016
SND1	staphylococcal nuclease and tudor domain containing 1	0.016
PSAP	prosaposin	0.016
EDEM2	ER degradation enhancer, mannosidase alpha-like 2	0.016
TSPO	translocator protein (18kDa)	0.016
PDPK1	3-phosphoinositide dependent protein kinase-1	0.016
MIF4GD	MIF4G domain containing	0.016
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.016
BCKDK	branched chain ketoacid dehydrogenase kinase	0.016
PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.016
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.016
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.016
CLEC4G	C-type lectin domain family 4, member G	0.016
GSTP1	glutathione S-transferase pi 1	0.016
CAPN1	calpain 1, (mu/I) large subunit	0.016
ING2	inhibitor of growth family, member 2	0.015
PPT1	palmitoyl-protein thioesterase 1	0.015
PYGM	phosphorylase, glycogen, muscle	0.015	Rat
C1orf63	chromosome 1 open reading frame 63	0.015
PID1	phosphotyrosine interaction domain containing 1	0.015
COPZ1	coatomer protein complex, subunit zeta 1	0.015
HDAC5	histone deacetylase 5	0.015
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.015
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.015
NAGK	N-acetylglucosamine kinase	0.015
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.015
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.015
BCAR1	breast cancer anti-estrogen resistance 1	0.015
MANBA	mannosidase, beta A, lysosomal	0.015
SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	0.015
HABP4	hyaluronan binding protein 4	0.015
ACTN3	actinin, alpha 3	0.015
PRKCA	protein kinase C, alpha	0.015
APOC2	apolipoprotein C-II	0.014
HEXB	hexosaminidase B (beta polypeptide)	0.014	Mouse
GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	0.014
BCAP31	B-cell receptor-associated protein 31	0.014
ERP29	endoplasmic reticulum protein 29	0.014
AQP7	aquaporin 7	0.014
C7orf68	chromosome 7 open reading frame 68	0.014
RXRG	retinoid X receptor, gamma	0.014
CFL1	cofilin 1 (non-muscle)	0.014
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.014
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.014
SIRT1	sirtuin 1	0.014
ADRBK1	adrenergic, beta, receptor kinase 1	0.014
RAB10	RAB10, member RAS oncogene family	0.014
PRCP	prolylcarboxypeptidase (angiotensinase C)	0.014
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.014
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.014
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.014
FLOT2	flotillin 2	0.013
UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	0.013
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.013
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.013
ERO1L	ERO1-like (S. cerevisiae)	0.013
STAT5A	signal transducer and activator of transcription 5A	0.013
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.013
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.013
JAK2	Janus kinase 2	0.013
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.013
TM9SF4	transmembrane 9 superfamily protein member 4	0.013
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.013
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.013
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.013
GUSB	glucuronidase, beta	0.013
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.013
TNNT3	troponin T type 3 (skeletal, fast)	0.013
ENO3	enolase 3 (beta, muscle)	0.013	Yeast
HP	haptoglobin	0.012
PFKFB4	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	0.012	Human
C3orf1	chromosome 3 open reading frame 1	0.012
NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	0.012
TCAP	titin-cap (telethonin)	0.012
TARBP1	TAR (HIV-1) RNA binding protein 1	0.012
PPP1R10	protein phosphatase 1, regulatory (inhibitor) subunit 10	0.012
CLCN1	chloride channel 1, skeletal muscle	0.012
CDK6	cyclin-dependent kinase 6	0.012
SNX17	sorting nexin 17	0.012
PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.012
PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.012
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.012
CD33	CD33 molecule	0.012
ALDOB	aldolase B, fructose-bisphosphate	0.012
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.012
GRB14	growth factor receptor-bound protein 14	0.012
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.012
GNPDA1	glucosamine-6-phosphate deaminase 1	0.012
ESRRB	estrogen-related receptor beta	0.012
MUC20	mucin 20, cell surface associated	0.012
METTL3	methyltransferase like 3	0.012
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.012
F10	coagulation factor X	0.012
HK2	hexokinase 2	0.012	Yeast
PUS7L	pseudouridylate synthase 7 homolog (S. cerevisiae)-like	0.011
DLG4	discs, large homolog 4 (Drosophila)	0.011
AGK	acylglycerol kinase	0.011
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.011
FBXO6	F-box protein 6	0.011
GM2A	GM2 ganglioside activator	0.011	Mouse
GSK3B	glycogen synthase kinase 3 beta	0.011
IGFBP3	insulin-like growth factor binding protein 3	0.011
FOXO3	forkhead box O3	0.011
P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	0.011
JAK1	Janus kinase 1	0.011
TRIM32	tripartite motif containing 32	0.011
ENSA	endosulfine alpha	0.011
MORC4	MORC family CW-type zinc finger 4	0.011
IGFBP5	insulin-like growth factor binding protein 5	0.011
SSX4	synovial sarcoma, X breakpoint 4	0.011
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.011
CKMT2	creatine kinase, mitochondrial 2 (sarcomeric)	0.011
TCTN3	tectonic family member 3	0.011
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.011
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.011
ANGPTL4	angiopoietin-like 4	0.011
BCL3	B-cell CLL/lymphoma 3	0.011
TRAP1	TNF receptor-associated protein 1	0.011
MYBPC2	myosin binding protein C, fast type	0.011
APOE	apolipoprotein E	0.011
ASL	argininosuccinate lyase	0.011
LNX1	ligand of numb-protein X 1	0.011
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.011
PLAUR	plasminogen activator, urokinase receptor	0.011
CKM	creatine kinase, muscle	0.011
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.011
AK4	adenylate kinase 4	0.011
ERRFI1	ERBB receptor feedback inhibitor 1	0.011
DCN	decorin	0.011
PRNP	prion protein	0.011
STC2	stanniocalcin 2	0.011
ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	0.011
NCOA2	nuclear receptor coactivator 2	0.011
CD4	CD4 molecule	0.011
PTPRF	protein tyrosine phosphatase, receptor type, F	0.011
TNNI2	troponin I type 2 (skeletal, fast)	0.011
PHKG1	phosphorylase kinase, gamma 1 (muscle)	0.011
SARDH	sarcosine dehydrogenase	0.011
TRPV6	transient receptor potential cation channel, subfamily V, member 6	0.011
SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1	0.011
PDXK	pyridoxal (pyridoxine, vitamin B6) kinase	0.011
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.010
ARF3	ADP-ribosylation factor 3	0.010
P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	0.010
HAUS4	HAUS augmin-like complex, subunit 4	0.010
HAAO	3-hydroxyanthranilate 3,4-dioxygenase	0.010
FAM103A1	family with sequence similarity 103, member A1	0.010
FANCA	Fanconi anemia, complementation group A	0.010
ELP4	elongation protein 4 homolog (S. cerevisiae)	0.010
HRC	histidine rich calcium binding protein	0.010
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.010
MYBPH	myosin binding protein H	0.010
AR	androgen receptor	0.010
BBS7	Bardet-Biedl syndrome 7	0.010
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	0.010
LDHC	lactate dehydrogenase C	0.010
SS18	synovial sarcoma translocation, chromosome 18	0.010
ETHE1	ethylmalonic encephalopathy 1	0.010