IMP
Process View
negative regulation of protein localization to nucleus
Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of protein localization to nucleus"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.807 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.695 | ||
| BTRC | beta-transducin repeat containing | 0.460 | Fly | |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.435 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.432 | ||
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.327 | ||
| CREBBP | CREB binding protein | 0.315 | ||
| DTX3L | deltex 3-like (Drosophila) | 0.276 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.270 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.264 | ||
| ZNF420 | zinc finger protein 420 | 0.240 | ||
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.233 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.223 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.191 | Rat | |
| DYRK1B | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | 0.187 | Human | |
| GSK3B | glycogen synthase kinase 3 beta | 0.175 | ||
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.174 | Human | |
| AXIN1 | axin 1 | 0.172 | Human | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.166 | ||
| RB1 | retinoblastoma 1 | 0.139 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.129 | ||
| SLMAP | sarcolemma associated protein | 0.113 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.112 | ||
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.110 | ||
| ZNF529 | zinc finger protein 529 | 0.107 | ||
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.105 | ||
| PKD1 | polycystic kidney disease 1 (autosomal dominant) | 0.101 | Mouse | |
| GCC1 | GRIP and coiled-coil domain containing 1 | 0.099 | ||
| RARA | retinoic acid receptor, alpha | 0.096 | ||
| APC | adenomatous polyposis coli | 0.085 | Human | |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.081 | Mouse Fly | |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.075 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.075 | ||
| ERBB2IP | erbb2 interacting protein | 0.071 | ||
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.069 | ||
| STRN3 | striatin, calmodulin binding protein 3 | 0.066 | ||
| RANBP3 | RAN binding protein 3 | 0.066 | ||
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.064 | ||
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.063 | ||
| LZTS2 | leucine zipper, putative tumor suppressor 2 | 0.062 | Mouse | |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.061 | ||
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.058 | ||
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.055 | ||
| PML | promyelocytic leukemia | 0.055 | ||
| LATS1 | LATS, large tumor suppressor, homolog 1 (Drosophila) | 0.054 | ||
| HIPK3 | homeodomain interacting protein kinase 3 | 0.052 | ||
| CKAP5 | cytoskeleton associated protein 5 | 0.050 | ||
| TEK | TEK tyrosine kinase, endothelial | 0.050 | ||
| ZNF432 | zinc finger protein 432 | 0.047 | ||
| ZNF84 | zinc finger protein 84 | 0.046 | ||
| PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.041 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.041 | ||
| AXL | AXL receptor tyrosine kinase | 0.040 | ||
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.039 | ||
| FAS | Fas (TNF receptor superfamily, member 6) | 0.039 | ||
| ZNF260 | zinc finger protein 260 | 0.036 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.036 | ||
| IFIH1 | interferon induced with helicase C domain 1 | 0.035 | ||
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.035 | Human | |
| MOBKL1A | MOB1, Mps One Binder kinase activator-like 1A (yeast) | 0.035 | ||
| EFCAB4B | EF-hand calcium binding domain 4B | 0.034 | ||
| HIPK2 | homeodomain interacting protein kinase 2 | 0.033 | ||
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.033 | ||
| CDK9 | cyclin-dependent kinase 9 | 0.033 | ||
| BBS10 | Bardet-Biedl syndrome 10 | 0.032 | ||
| TJP2 | tight junction protein 2 (zona occludens 2) | 0.031 | ||
| LMO4 | LIM domain only 4 | 0.031 | ||
| INSR | insulin receptor | 0.030 | Worm | |
| HDAC2 | histone deacetylase 2 | 0.029 | ||
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.029 | ||
| YAP1 | Yes-associated protein 1 | 0.029 | Human | |
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.029 | ||
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 | 0.028 | Human | |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 | 0.027 | ||
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.026 | ||
| PROX1 | prospero homeobox 1 | 0.026 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.026 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.026 | ||
| ZNF585A | zinc finger protein 585A | 0.026 | ||
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.025 | ||
| GLI1 | GLI family zinc finger 1 | 0.025 | ||
| IRS1 | insulin receptor substrate 1 | 0.025 | ||
| ACTN1 | actinin, alpha 1 | 0.025 | ||
| IRS2 | insulin receptor substrate 2 | 0.025 | ||
| ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.025 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.025 | Human | |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.025 | ||
| AMOTL1 | angiomotin like 1 | 0.024 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.023 | Human Rat | |
| IGF1R | insulin-like growth factor 1 receptor | 0.023 | Worm | |
| PEX26 | peroxisomal biogenesis factor 26 | 0.023 | ||
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.023 | ||
| ZNF571 | zinc finger protein 571 | 0.023 | ||
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.023 | ||
| MED24 | mediator complex subunit 24 | 0.022 | ||
| ZNF140 | zinc finger protein 140 | 0.021 | Human | |
| HCFC1 | host cell factor C1 (VP16-accessory protein) | 0.021 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.021 | ||
| FLNB | filamin B, beta | 0.021 | ||
| SMAD3 | SMAD family member 3 | 0.021 | ||
| CSNK1E | casein kinase 1, epsilon | 0.021 | ||
| NOG | noggin | 0.021 | ||
| SMAD1 | SMAD family member 1 | 0.020 | ||
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.020 | ||
| AMMECR1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | 0.020 | ||
| TP73 | tumor protein p73 | 0.020 | ||
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | 0.020 | ||
| EEF2K | eukaryotic elongation factor-2 kinase | 0.020 | ||
| OPTN | optineurin | 0.019 | ||
| ZNF304 | zinc finger protein 304 | 0.019 | ||
| PPP6C | protein phosphatase 6, catalytic subunit | 0.019 | ||
| HOXA9 | homeobox A9 | 0.019 | ||
| GLIS2 | GLIS family zinc finger 2 | 0.019 | ||
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.019 | ||
| PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.018 | ||
| PRKCA | protein kinase C, alpha | 0.018 | ||
| DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.018 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.018 | ||
| ZNF12 | zinc finger protein 12 | 0.018 | ||
| ZNF512B | zinc finger protein 512B | 0.018 | ||
| ATXN3 | ataxin 3 | 0.018 | ||
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.018 | ||
| FZD5 | frizzled homolog 5 (Drosophila) | 0.017 | ||
| ACTN4 | actinin, alpha 4 | 0.017 | ||
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 0.017 | ||
| AMOTL2 | angiomotin like 2 | 0.017 | ||
| RABAC1 | Rab acceptor 1 (prenylated) | 0.017 | ||
| TRIM41 | tripartite motif containing 41 | 0.017 | ||
| H2AFX | H2A histone family, member X | 0.017 | ||
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.017 | ||
| ZNF83 | zinc finger protein 83 | 0.016 | ||
| VASP | vasodilator-stimulated phosphoprotein | 0.016 | ||
| ANKRD28 | ankyrin repeat domain 28 | 0.016 | ||
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.016 | ||
| NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.016 | ||
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.016 | ||
| MID1IP1 | MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish)) | 0.016 | ||
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.016 | ||
| PRKCZ | protein kinase C, zeta | 0.015 | ||
| ZNF746 | zinc finger protein 746 | 0.015 | ||
| PHF19 | PHD finger protein 19 | 0.015 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.015 | ||
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 | 0.015 | ||
| ZNF569 | zinc finger protein 569 | 0.015 | ||
| C19orf46 | chromosome 19 open reading frame 46 | 0.015 | ||
| MAPK6 | mitogen-activated protein kinase 6 | 0.015 | ||
| CALD1 | caldesmon 1 | 0.015 | ||
| C10orf116 | chromosome 10 open reading frame 116 | 0.015 | ||
| STRN | striatin, calmodulin binding protein | 0.015 | ||
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.015 | ||
| ZNF227 | zinc finger protein 227 | 0.015 | ||
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.015 | ||
| FBXO33 | F-box protein 33 | 0.015 | ||
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.014 | ||
| HDAC1 | histone deacetylase 1 | 0.014 | ||
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | 0.014 | ||
| EMD | emerin | 0.014 | ||
| RANBP9 | RAN binding protein 9 | 0.014 | ||
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.014 | ||
| AXIN2 | axin 2 | 0.014 | ||
| DEPTOR | DEP domain containing MTOR-interacting protein | 0.014 | ||
| FGFR1 | fibroblast growth factor receptor 1 | 0.014 | ||
| TSC1 | tuberous sclerosis 1 | 0.014 | ||
| ZNF263 | zinc finger protein 263 | 0.014 | ||
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.014 | ||
| NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.014 | ||
| ZNF189 | zinc finger protein 189 | 0.014 | ||
| WDR26 | WD repeat domain 26 | 0.013 | ||
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.013 | ||
| ZNF764 | zinc finger protein 764 | 0.013 | ||
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.013 | ||
| FAM117B | family with sequence similarity 117, member B | 0.013 | ||
| DUSP3 | dual specificity phosphatase 3 | 0.013 | ||
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.013 | Human | |
| GLIS3 | GLIS family zinc finger 3 | 0.013 | ||
| ZNF302 | zinc finger protein 302 | 0.013 | Human | |
| FERMT2 | fermitin family member 2 | 0.013 | ||
| SCRIB | scribbled homolog (Drosophila) | 0.013 | ||
| ZNF45 | zinc finger protein 45 | 0.013 | ||
| PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.013 | ||
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.013 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.013 | ||
| AKAP8L | A kinase (PRKA) anchor protein 8-like | 0.013 | ||
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.013 | ||
| TBK1 | TANK-binding kinase 1 | 0.012 | ||
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.012 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.012 | ||
| ZFP30 | zinc finger protein 30 homolog (mouse) | 0.012 | ||
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.012 | ||
| POLI | polymerase (DNA directed) iota | 0.012 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.012 | ||
| NCOA6 | nuclear receptor coactivator 6 | 0.012 | ||
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.012 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.012 | ||
| TRAF6 | TNF receptor-associated factor 6 | 0.012 | ||
| MPDZ | multiple PDZ domain protein | 0.012 | ||
| PAAF1 | proteasomal ATPase-associated factor 1 | 0.012 | ||
| FHL3 | four and a half LIM domains 3 | 0.012 | ||
| C1orf93 | chromosome 1 open reading frame 93 | 0.012 | ||
| ZNF581 | zinc finger protein 581 | 0.012 | ||
| HMG20A | high mobility group 20A | 0.012 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.012 | ||
| ZNF805 | zinc finger protein 805 | 0.012 | Human | |
| TP63 | tumor protein p63 | 0.012 | ||
| VCP | valosin containing protein | 0.012 | ||
| RNF213 | ring finger protein 213 | 0.011 | ||
| CTTNBP2NL | CTTNBP2 N-terminal like | 0.011 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.011 | ||
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A | 0.011 | ||
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.011 | ||
| HDAC6 | histone deacetylase 6 | 0.011 | ||
| RAB21 | RAB21, member RAS oncogene family | 0.011 | ||
| CLPX | ClpX caseinolytic peptidase X homolog (E. coli) | 0.011 | ||
| PPP1R3F | protein phosphatase 1, regulatory (inhibitor) subunit 3F | 0.011 | ||
| CNN2 | calponin 2 | 0.011 | ||
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta | 0.011 | ||
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.011 | ||
| ZNF567 | zinc finger protein 567 | 0.011 | ||
| RBM12B | RNA binding motif protein 12B | 0.011 | ||
| HECTD1 | HECT domain containing 1 | 0.011 | ||
| GRB10 | growth factor receptor-bound protein 10 | 0.011 | ||
| MYH9 | myosin, heavy chain 9, non-muscle | 0.011 | ||
| PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 0.011 | ||
| ZNF187 | zinc finger protein 187 | 0.011 | ||
| PSEN1 | presenilin 1 | 0.011 | ||
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.011 | ||
| FAM13B | family with sequence similarity 13, member B | 0.011 | ||
| LASP1 | LIM and SH3 protein 1 | 0.011 | ||
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.011 | ||
| RUNX1 | runt-related transcription factor 1 | 0.011 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.011 | ||
| SMS | spermine synthase | 0.011 | ||
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 | 0.011 | ||
| FAM40A | family with sequence similarity 40, member A | 0.011 | ||
| QPRT | quinolinate phosphoribosyltransferase | 0.011 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.011 | ||
| CLEC3B | C-type lectin domain family 3, member B | 0.011 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.011 | ||
| ZBTB8A | zinc finger and BTB domain containing 8A | 0.011 | ||
| PPP1R16A | protein phosphatase 1, regulatory (inhibitor) subunit 16A | 0.011 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.011 | ||
| IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.011 | ||
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.010 | ||
| EIF3C | eukaryotic translation initiation factor 3, subunit C | 0.010 | ||
| TOX4 | TOX high mobility group box family member 4 | 0.010 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.010 | ||
| KAT2B | K(lysine) acetyltransferase 2B | 0.010 | ||
| ZNF559 | zinc finger protein 559 | 0.010 | ||
| C16orf72 | chromosome 16 open reading frame 72 | 0.010 | ||
| TGIF1 | TGFB-induced factor homeobox 1 | 0.010 | ||
| MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.010 | ||
| PYDC2 | pyrin domain containing 2 | 0.010 | ||
| SAMD9L | sterile alpha motif domain containing 9-like | 0.010 | ||
| BRAP | BRCA1 associated protein | 0.010 | ||
| CUL1 | cullin 1 | 0.010 | ||
| ZNF623 | zinc finger protein 623 | 0.010 | ||
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.010 | ||
| ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.010 |