IMP

Process View

Mus musculus

21 genes annotated in mouse

Multi-species View

regulation of interleukin 10 production

GO:0032653

Any process that modulates the frequency, rate, or extent of interleukin-10 production.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 10 production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 10 production" (in gray)

Name	Description	Probability	Func Analog Organism
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.975
Tnf	tumor necrosis factor	0.970
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.862
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.773
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.675
Il2rg	interleukin 2 receptor, gamma chain	0.623
Ptprc	protein tyrosine phosphatase, receptor type, C	0.611
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.544
Lyz2	lysozyme 2	0.522
Casp1	caspase 1	0.448
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.423
Ifng	interferon gamma	0.387
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.385
Myd88	myeloid differentiation primary response gene 88	0.341
Cd44	CD44 antigen	0.281
Cd40	CD40 antigen	0.274	Mouse
Fas	Fas (TNF receptor superfamily member 6)	0.266
Igh	immunoglobulin heavy chain complex	0.201
Btk	Bruton agammaglobulinemia tyrosine kinase	0.197
Stat3	signal transducer and activator of transcription 3	0.187
Cd28	CD28 antigen	0.171
Ticam1	toll-like receptor adaptor molecule 1	0.157
Ccr6	chemokine (C-C motif) receptor 6	0.149
Tnip1	TNFAIP3 interacting protein 1	0.148
Ikzf1	IKAROS family zinc finger 1	0.147
Cd19	CD19 antigen	0.146
Socs1	suppressor of cytokine signaling 1	0.145
Pycard	PYD and CARD domain containing	0.143	Human
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.135
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.134
Gbp5	guanylate binding protein 5	0.124
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.109
Ccl4	chemokine (C-C motif) ligand 4	0.108
Birc3	baculoviral IAP repeat-containing 3	0.108
Il4	interleukin 4	0.106
Pdcd1	programmed cell death 1	0.101
Bcl6	B-cell leukemia/lymphoma 6	0.093
Bcl3	B-cell leukemia/lymphoma 3	0.091
Pou2af1	POU domain, class 2, associating factor 1	0.089
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.086
Lat	linker for activation of T cells	0.084
Inpp5d	inositol polyphosphate-5-phosphatase D	0.081
Tnfrsf13b	tumor necrosis factor receptor superfamily, member 13b	0.078
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.072
Ccr7	chemokine (C-C motif) receptor 7	0.069
Aim2	absent in melanoma 2	0.067
Clec4n	C-type lectin domain family 4, member n	0.066
Il10	interleukin 10	0.065
Lta	lymphotoxin A	0.059
Vav1	vav 1 oncogene	0.054
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.052
Fasl	Fas ligand (TNF superfamily, member 6)	0.050
Cd14	CD14 antigen	0.047
Col11a2	collagen, type XI, alpha 2	0.045
Rag2	recombination activating gene 2	0.045
Gpr132	G protein-coupled receptor 132	0.044
Ldb3	LIM domain binding 3	0.042
Prkcd	protein kinase C, delta	0.042	Mouse
Ebi3	Epstein-Barr virus induced gene 3	0.041
Sfpi1	SFFV proviral integration 1	0.041
Lyn	Yamaguchi sarcoma viral (v-yes-1) oncogene homolog	0.039
2010106G01Rik	RIKEN cDNA 2010106G01 gene	0.038
Traf6	TNF receptor-associated factor 6	0.038
Notch1	Notch gene homolog 1 (Drosophila)	0.037
Il27ra	interleukin 27 receptor, alpha	0.035
C1qb	complement component 1, q subcomponent, beta polypeptide	0.033
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.033
Pik3cg	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.032
Elane	elastase, neutrophil expressed	0.032
Pdcd1lg2	programmed cell death 1 ligand 2	0.032
Csf1r	colony stimulating factor 1 receptor	0.031
Icos	inducible T-cell co-stimulator	0.031
Cd4	CD4 antigen	0.030
Cd300ld	CD300 molecule-like family member d	0.029
Hspa9	heat shock protein 9	0.028
Ifngr1	interferon gamma receptor 1	0.028
Mefv	Mediterranean fever	0.027
Lck	lymphocyte protein tyrosine kinase	0.026
Il4ra	interleukin 4 receptor, alpha	0.026
Il1b	interleukin 1 beta	0.026
Il12b	interleukin 12b	0.025
Hbb-y	hemoglobin Y, beta-like embryonic chain	0.025
Ms4a2	membrane-spanning 4-domains, subfamily A, member 2	0.025
Cd86	CD86 antigen	0.025
Il1r1	interleukin 1 receptor, type I	0.024
Socs3	suppressor of cytokine signaling 3	0.024
Ccr1	chemokine (C-C motif) receptor 1	0.023
Spp1	secreted phosphoprotein 1	0.023
Psg21	pregnancy-specific glycoprotein 21	0.023	Mouse
Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D	0.023
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.023
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.023
Duox2	dual oxidase 2	0.022
Batf	basic leucine zipper transcription factor, ATF-like	0.022
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.022
Junb	Jun-B oncogene	0.021
Tlr2	toll-like receptor 2	0.020	Mouse
Nlrp3	NLR family, pyrin domain containing 3	0.020	Mouse
Siglece	sialic acid binding Ig-like lectin E	0.020
Tlr4	toll-like receptor 4	0.020
Trem3	triggering receptor expressed on myeloid cells 3	0.019
Il6	interleukin 6	0.019
Gdf3	growth differentiation factor 3	0.019
Slc26a4	solute carrier family 26, member 4	0.019
Slamf1	signaling lymphocytic activation molecule family member 1	0.019
Cd80	CD80 antigen	0.019
Fgd3	FYVE, RhoGEF and PH domain containing 3	0.019
Blk	B lymphoid kinase	0.019
Nos2	nitric oxide synthase 2, inducible	0.018
Plek	pleckstrin	0.018
Irf1	interferon regulatory factor 1	0.018
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.018
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.018	Mouse
Akt2	thymoma viral proto-oncogene 2	0.017	Mouse
Unc93b1	unc-93 homolog B1 (C. elegans)	0.017
Il22	interleukin 22	0.017
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.017
Notch2	Notch gene homolog 2 (Drosophila)	0.017
Naip1	NLR family, apoptosis inhibitory protein 1	0.017
Akt1	thymoma viral proto-oncogene 1	0.016	Mouse
Klf1	Kruppel-like factor 1 (erythroid)	0.016
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.016
Cyld	cylindromatosis (turban tumor syndrome)	0.015
Crb2	crumbs homolog 2 (Drosophila)	0.015
Tcra	T-cell receptor alpha chain	0.015
Irg1	immunoresponsive gene 1	0.015
Prf1	perforin 1 (pore forming protein)	0.015
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.014
Lcp1	lymphocyte cytosolic protein 1	0.014
Fcgr2b	Fc receptor, IgG, low affinity IIb	0.014
Sh2d2a	SH2 domain protein 2A	0.014
Rel	reticuloendotheliosis oncogene	0.014
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.014
Ooep	oocyte expressed protein homolog (dog)	0.014
Gypa	glycophorin A	0.014
Lair1	leukocyte-associated Ig-like receptor 1	0.014
Car1	carbonic anhydrase 1	0.014
Il2rb	interleukin 2 receptor, beta chain	0.014
Tomm40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.014
Tnfsf18	tumor necrosis factor (ligand) superfamily, member 18	0.014
Tbxas1	thromboxane A synthase 1, platelet	0.013
Chd7	chromodomain helicase DNA binding protein 7	0.013
Ermap	erythroblast membrane-associated protein	0.013
Vpreb3	pre-B lymphocyte gene 3	0.013
Spna1	spectrin alpha 1	0.013
Samd4b	sterile alpha motif domain containing 4B	0.013
Ccl12	chemokine (C-C motif) ligand 12	0.013
Ccr9	chemokine (C-C motif) receptor 9	0.013
Ctss	cathepsin S	0.013
Erv3	endogenous retroviral sequence 3	0.013
Jak1	Janus kinase 1	0.013	Mouse
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.012
Klf7	Kruppel-like factor 7 (ubiquitous)	0.012
Ccr8	chemokine (C-C motif) receptor 8	0.012
Il2ra	interleukin 2 receptor, alpha chain	0.012
Nlrp6	NLR family, pyrin domain containing 6	0.012	Mouse
Traf3	TNF receptor-associated factor 3	0.012
Cd5	CD5 antigen	0.012
Sele	selectin, endothelial cell	0.012
Ccl3	chemokine (C-C motif) ligand 3	0.012
Tlr6	toll-like receptor 6	0.012	Mouse
C3	complement component 3	0.012
Il7r	interleukin 7 receptor	0.012
Cd96	CD96 antigen	0.012
Prkce	protein kinase C, epsilon	0.012
Foxp1	forkhead box P1	0.012	Mouse
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.012
Fyn	Fyn proto-oncogene	0.012
Robo3	roundabout homolog 3 (Drosophila)	0.012
Plac1	placental specific protein 1	0.012
Samsn1	SAM domain, SH3 domain and nuclear localization signals, 1	0.011	Mouse
Cblb	Casitas B-lineage lymphoma b	0.011
Sh2b1	SH2B adaptor protein 1	0.011
Zfp36	zinc finger protein 36	0.011
C3ar1	complement component 3a receptor 1	0.011
Cr2	complement receptor 2	0.011
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.011
Il12rb1	interleukin 12 receptor, beta 1	0.011
P2ry6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.011
Ccbp2	chemokine binding protein 2	0.011
Runx3	runt related transcription factor 3	0.011
Traf2	TNF receptor-associated factor 2	0.011
Treml1	triggering receptor expressed on myeloid cells-like 1	0.011
Ccl2	chemokine (C-C motif) ligand 2	0.011
Lcn4	lipocalin 4	0.011
Psg18	pregnancy specific glycoprotein 18	0.011
Msr1	macrophage scavenger receptor 1	0.011
Gzmb	granzyme B	0.011
Ptafr	platelet-activating factor receptor	0.011
Ms4a6b	membrane-spanning 4-domains, subfamily A, member 6B	0.011
Tlr1	toll-like receptor 1	0.011	Mouse
Zap70	zeta-chain (TCR) associated protein kinase	0.011
Mmp1a	matrix metallopeptidase 1a (interstitial collagenase)	0.011
Cd6	CD6 antigen	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.010
Cd300lf	CD300 antigen like family member F	0.010
Prss2	protease, serine, 2	0.010
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.010
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.010
Tac4	tachykinin 4	0.010
Prl3a1	prolactin family 3, subfamily a, member 1	0.010
Cxcl2	chemokine (C-X-C motif) ligand 2	0.010
Naip2	NLR family, apoptosis inhibitory protein 2	0.010
Il18	interleukin 18	0.010