IMP

Process View

Mus musculus

13 genes annotated in mouse

cellular response to glucocorticoid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to glucocorticoid stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to glucocorticoid stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.962	Mouse
Lyz2	lysozyme 2	0.922
Vegfa	vascular endothelial growth factor A	0.893
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.877
Pitx2	paired-like homeodomain transcription factor 2	0.821
Ptgs2	prostaglandin-endoperoxide synthase 2	0.812
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.689	Rat
Trim55	tripartite motif-containing 55	0.674	Mouse
Tgfb1	transforming growth factor, beta 1	0.600	Mouse Rat
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.592
Ren1	renin 1 structural	0.564
Pax3	paired box gene 3	0.509
Hif1a	hypoxia inducible factor 1, alpha subunit	0.486
Gata4	GATA binding protein 4	0.484
Dmd	dystrophin, muscular dystrophy	0.456
Tgfbr2	transforming growth factor, beta receptor II	0.395
Agtr1a	angiotensin II receptor, type 1a	0.393	Rat
Fgfr2	fibroblast growth factor receptor 2	0.392
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.375
Foxc1	forkhead box C1	0.353
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.349
Adam17	a disintegrin and metallopeptidase domain 17	0.335
Gbp5	guanylate binding protein 5	0.321
Mstn	myostatin	0.311
Nos1	nitric oxide synthase 1, neuronal	0.285
Osmr	oncostatin M receptor	0.273
Csf1	colony stimulating factor 1 (macrophage)	0.267
H2-Eb1	histocompatibility 2, class II antigen E beta	0.262
Tgfb2	transforming growth factor, beta 2	0.223	Mouse
Stat3	signal transducer and activator of transcription 3	0.213
Rb1	retinoblastoma 1	0.206
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.187	Rat
Trim63	tripartite motif-containing 63	0.187
Fst	follistatin	0.167
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.147
Lepr	leptin receptor	0.134
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.134
Casp1	caspase 1	0.132	Mouse
Pycard	PYD and CARD domain containing	0.118
Pax6	paired box gene 6	0.110
Fbn1	fibrillin 1	0.105
Wwox	WW domain-containing oxidoreductase	0.101
Pomc	pro-opiomelanocortin-alpha	0.097
Rxra	retinoid X receptor alpha	0.096
Ctnnb1	catenin (cadherin associated protein), beta 1	0.095
Meox2	mesenchyme homeobox 2	0.090
Shh	sonic hedgehog	0.088
Myf6	myogenic factor 6	0.084	Mouse
Htt	huntingtin	0.084
Klf3	Kruppel-like factor 3 (basic)	0.083
Il18	interleukin 18	0.079
Il6st	interleukin 6 signal transducer	0.079
Smad3	MAD homolog 3 (Drosophila)	0.078
Hbegf	heparin-binding EGF-like growth factor	0.077
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.077
Tgfbr1	transforming growth factor, beta receptor I	0.074
Plau	plasminogen activator, urokinase	0.070
Thbs1	thrombospondin 1	0.070
Prlr	prolactin receptor	0.069
Myf5	myogenic factor 5	0.068	Mouse
Ptprc	protein tyrosine phosphatase, receptor type, C	0.067
Vhl	von Hippel-Lindau tumor suppressor	0.067
Egfr	epidermal growth factor receptor	0.067	Rat
Il1r1	interleukin 1 receptor, type I	0.064
Hand2	heart and neural crest derivatives expressed transcript 2	0.063
Jag1	jagged 1	0.063
Slc12a1	solute carrier family 12, member 1	0.062
Errfi1	ERBB receptor feedback inhibitor 1	0.061
Esr1	estrogen receptor 1 (alpha)	0.061
Nos3	nitric oxide synthase 3, endothelial cell	0.061
Lep	leptin	0.059
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.057
Gja1	gap junction protein, alpha 1	0.054
Il1b	interleukin 1 beta	0.054
Aim2	absent in melanoma 2	0.050
Apc	adenomatosis polyposis coli	0.050
Lhx3	LIM homeobox protein 3	0.049
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.048
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.047
Vdr	vitamin D receptor	0.046
H2-DMa	histocompatibility 2, class II, locus DMa	0.046
Hr	hairless	0.044
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.043
Socs5	suppressor of cytokine signaling 5	0.042
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.042
Rbl2	retinoblastoma-like 2	0.039
Rora	RAR-related orphan receptor alpha	0.038
Sox4	SRY-box containing gene 4	0.037
Lox	lysyl oxidase	0.036
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.035
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.035
Pax7	paired box gene 7	0.035
Nf1	neurofibromatosis 1	0.035
Mybph	myosin binding protein H	0.034
Klhl24	kelch-like 24 (Drosophila)	0.034
Tnni2	troponin I, skeletal, fast 2	0.033
Cd14	CD14 antigen	0.033
Foxp3	forkhead box P3	0.033
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.032
Esr2	estrogen receptor 2 (beta)	0.031
Hsd3b2	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	0.030	Rat
Cdk5r1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.030
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.030	Mouse
Drd2	dopamine receptor D2	0.030
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.028
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.028
Fgf10	fibroblast growth factor 10	0.028
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.028
Arnt	aryl hydrocarbon receptor nuclear translocator	0.028
Rod1	ROD1 regulator of differentiation 1 (S. pombe)	0.028
Cyld	cylindromatosis (turban tumor syndrome)	0.027
Ar	androgen receptor	0.027
Notch2	Notch gene homolog 2 (Drosophila)	0.026
Ciita	class II transactivator	0.026
Isl1	ISL1 transcription factor, LIM/homeodomain	0.026	Rat
Cyr61	cysteine rich protein 61	0.025
Dysf	dysferlin	0.025
Tcfap2a	transcription factor AP-2, alpha	0.025
F13b	coagulation factor XIII, beta subunit	0.024
Zfpm2	zinc finger protein, multitype 2	0.024
Myod1	myogenic differentiation 1	0.023
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.023
Ch25h	cholesterol 25-hydroxylase	0.023
Jak2	Janus kinase 2	0.023
Birc3	baculoviral IAP repeat-containing 3	0.022
Keg1	kidney expressed gene 1	0.022
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.022
Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	0.022
Cp	ceruloplasmin	0.022
Myog	myogenin	0.022	Mouse
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.021
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.021
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.021
Myc	myelocytomatosis oncogene	0.021
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.021
Dmgdh	dimethylglycine dehydrogenase precursor	0.021
Hp	haptoglobin	0.020
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.020
Gata6	GATA binding protein 6	0.020
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.020
Tgm3	transglutaminase 3, E polypeptide	0.020
Ghr	growth hormone receptor	0.019
Fbxl3	F-box and leucine-rich repeat protein 3	0.019
Arx	aristaless related homeobox	0.019
Serping1	serine (or cysteine) peptidase inhibitor, clade G, member 1	0.019
Ccl9	chemokine (C-C motif) ligand 9	0.019
Cxcl1	chemokine (C-X-C motif) ligand 1	0.019
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.018
Eif3f	eukaryotic translation initiation factor 3, subunit F	0.018
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.018
Gna13	guanine nucleotide binding protein, alpha 13	0.017
Ugt2b38	UDP glucuronosyltransferase 2 family, polypeptide B38	0.017	Rat
Psmb9	proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)	0.016
Yap1	yes-associated protein 1	0.016
Krt25	keratin 25	0.016
Cav1	caveolin 1, caveolae protein	0.016
Socs3	suppressor of cytokine signaling 3	0.016
Pten	phosphatase and tensin homolog	0.016
Tead3	TEA domain family member 3	0.016
Tmpo	thymopoietin	0.016
Mdfi	MyoD family inhibitor	0.016
Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	0.016
Hsd3b6	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6	0.016	Rat
Onecut1	one cut domain, family member 1	0.016
Insr	insulin receptor	0.015
Fshr	follicle stimulating hormone receptor	0.015
Fas	Fas (TNF receptor superfamily member 6)	0.015
Mc5r	melanocortin 5 receptor	0.015
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.015
Klf6	Kruppel-like factor 6	0.015
Cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.015
Bmp2	bone morphogenetic protein 2	0.015
Rarb	retinoic acid receptor, beta	0.015
Dsg4	desmoglein 4	0.015
Cyp11b2	cytochrome P450, family 11, subfamily b, polypeptide 2	0.014
Inhba	inhibin beta-A	0.014
Ret	ret proto-oncogene	0.014
Cyp1b1	cytochrome P450, family 1, subfamily b, polypeptide 1	0.014
Lrg1	leucine-rich alpha-2-glycoprotein 1	0.013
Plin1	perilipin 1	0.013
Cacna1s	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.013
Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	0.013
Mesp1	mesoderm posterior 1	0.013
Ripk3	receptor-interacting serine-threonine kinase 3	0.013
Foxn1	forkhead box N1	0.013
Cyp2c54	cytochrome P450, family 2, subfamily c, polypeptide 54	0.013
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.013
Apaf1	apoptotic peptidase activating factor 1	0.013
Met	met proto-oncogene	0.013
Idua	iduronidase, alpha-L-	0.013
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.013
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.013
Tnfrsf11b	tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)	0.013
Ccl7	chemokine (C-C motif) ligand 7	0.013
Cxcr4	chemokine (C-X-C motif) receptor 4	0.012
Mobkl1b	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.012
Twist2	twist homolog 2 (Drosophila)	0.012
C4b	complement component 4B (Childo blood group)	0.012
Tfpi2	tissue factor pathway inhibitor 2	0.012
Ctsl	cathepsin L	0.012
Mbl1	mannose-binding lectin (protein A) 1	0.012
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.012	Rat
Atf4	activating transcription factor 4	0.012
Plac8	placenta-specific 8	0.012
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.012
Cbl	Casitas B-lineage lymphoma	0.012
Sox9	SRY-box containing gene 9	0.012
Otc	ornithine transcarbamylase	0.012
Zeb1	zinc finger E-box binding homeobox 1	0.011
Phox2b	paired-like homeobox 2b	0.011
Insm1	insulinoma-associated 1	0.011
Lif	leukemia inhibitory factor	0.011
Msn	moesin	0.011
Emp1	epithelial membrane protein 1	0.011
Ntf3	neurotrophin 3	0.011
Nrg1	neuregulin 1	0.011
Ext1	exostoses (multiple) 1	0.011
Thpo	thrombopoietin	0.011
AW112010	expressed sequence AW112010	0.011
Cyp2c38	cytochrome P450, family 2, subfamily c, polypeptide 38	0.011
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.011
Sos1	son of sevenless homolog 1 (Drosophila)	0.011
Anxa3	annexin A3	0.011
Gbp2	guanylate binding protein 2	0.011
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.011
Ccl8	chemokine (C-C motif) ligand 8	0.011
Cyp2j5	cytochrome P450, family 2, subfamily j, polypeptide 5	0.011
Lcn2	lipocalin 2	0.011
Agtrap	angiotensin II, type I receptor-associated protein	0.011
Mc2r	melanocortin 2 receptor	0.011
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.010
Vav3	vav 3 oncogene	0.010
Bmp4	bone morphogenetic protein 4	0.010	Rat
Socs1	suppressor of cytokine signaling 1	0.010
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.010
Cyp2f2	cytochrome P450, family 2, subfamily f, polypeptide 2	0.010
Il12a	interleukin 12a	0.010
Mybpc1	myosin binding protein C, slow-type	0.010
Cd47	CD47 antigen (Rh-related antigen, integrin-associated signal transducer)	0.010
C9	complement component 9	0.010
Nupr1	nuclear protein 1	0.010
Hrc	histidine rich calcium binding protein	0.010