IMP

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Mus musculus

1 genes annotated in mouse

smad protein complex assembly

The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "smad protein complex assembly"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "smad protein complex assembly" (in gray)

Name	Description	Probability	Func Analog Organism
Apc	adenomatosis polyposis coli	0.993
Smad4	MAD homolog 4 (Drosophila)	0.985	Human
Ctnnb1	catenin (cadherin associated protein), beta 1	0.761
Smad3	MAD homolog 3 (Drosophila)	0.758	Human Rat
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.661
Tbx5	T-box 5	0.566	Mouse
Smad1	MAD homolog 1 (Drosophila)	0.520	Human
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.430
Eya1	eyes absent 1 homolog (Drosophila)	0.413
Scn5a	sodium channel, voltage-gated, type V, alpha	0.394
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.381
Smad2	MAD homolog 2 (Drosophila)	0.361	Human
Hoxa1	homeobox A1	0.342
Pten	phosphatase and tensin homolog	0.311
Erbb2ip	Erbb2 interacting protein	0.309
Ptgs2	prostaglandin-endoperoxide synthase 2	0.309
Alx1	ALX homeobox 1	0.298
Vdr	vitamin D receptor	0.289
Lepr	leptin receptor	0.272
Il10	interleukin 10	0.254
Pitx1	paired-like homeodomain transcription factor 1	0.234
Otx2	orthodenticle homolog 2 (Drosophila)	0.231
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.214
Dll4	delta-like 4 (Drosophila)	0.210
Foxg1	forkhead box G1	0.202
Nos3	nitric oxide synthase 3, endothelial cell	0.200
Zmym2	zinc finger, MYM-type 2	0.198
Bptf	bromodomain PHD finger transcription factor	0.197
Lef1	lymphoid enhancer binding factor 1	0.182
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.181
Tbx3	T-box 3	0.177	Mouse
Shh	sonic hedgehog	0.171
Smad7	MAD homolog 7 (Drosophila)	0.170
Bdnf	brain derived neurotrophic factor	0.159
Braf	Braf transforming gene	0.159
Stat3	signal transducer and activator of transcription 3	0.150
Fgfr2	fibroblast growth factor receptor 2	0.148
Chd7	chromodomain helicase DNA binding protein 7	0.147
Prkg1	protein kinase, cGMP-dependent, type I	0.142
Axin1	axin 1	0.132
Csf1	colony stimulating factor 1 (macrophage)	0.119
Zeb1	zinc finger E-box binding homeobox 1	0.118
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.116
Ptch1	patched homolog 1	0.115
Pitx2	paired-like homeodomain transcription factor 2	0.114
Pax2	paired box gene 2	0.114
Sox2	SRY-box containing gene 2	0.106
Zic3	zinc finger protein of the cerebellum 3	0.105
Rxra	retinoid X receptor alpha	0.101
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.101
Nodal	nodal	0.098
Lrp6	low density lipoprotein receptor-related protein 6	0.096
Esr2	estrogen receptor 2 (beta)	0.095
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.095
Gsk3b	glycogen synthase kinase 3 beta	0.093
Efnb2	ephrin B2	0.093
Ifng	interferon gamma	0.088
Fgfr3	fibroblast growth factor receptor 3	0.088
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.085
Wt1	Wilms tumor 1 homolog	0.083
Htt	huntingtin	0.077
Sall1	sal-like 1 (Drosophila)	0.068
Kit	kit oncogene	0.067
Lif	leukemia inhibitory factor	0.066
Gata3	GATA binding protein 3	0.066
Esr1	estrogen receptor 1 (alpha)	0.061
Amhr2	anti-Mullerian hormone type 2 receptor	0.057
Il6st	interleukin 6 signal transducer	0.056
Ighmbp2	immunoglobulin mu binding protein 2	0.055
Rnf2	ring finger protein 2	0.055
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.054
Runx3	runt related transcription factor 3	0.054
Col1a1	collagen, type I, alpha 1	0.052
Nog	noggin	0.051
Tcf21	transcription factor 21	0.051
Pou5f1	POU domain, class 5, transcription factor 1	0.050
Nos2	nitric oxide synthase 2, inducible	0.048
Tlr4	toll-like receptor 4	0.047
Hmx3	H6 homeobox 3	0.046
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.046
Lmx1a	LIM homeobox transcription factor 1 alpha	0.044
Sall4	sal-like 4 (Drosophila)	0.043
Col13a1	collagen, type XIII, alpha 1	0.041
Mmp9	matrix metallopeptidase 9	0.039
Cd274	CD274 antigen	0.038
Noto	notochord homolog (Xenopus laevis)	0.038
Stk11	serine/threonine kinase 11	0.037
Kitl	kit ligand	0.037
Gja1	gap junction protein, alpha 1	0.036
Hoxd1	homeobox D1	0.035
Tbx4	T-box 4	0.035	Mouse
Trp63	transformation related protein 63	0.034
Nanog	Nanog homeobox	0.034
Vav3	vav 3 oncogene	0.034
Gja5	gap junction protein, alpha 5	0.033
Irx3	Iroquois related homeobox 3 (Drosophila)	0.033
Meox2	mesenchyme homeobox 2	0.032
Bmp4	bone morphogenetic protein 4	0.032
Tlr2	toll-like receptor 2	0.032
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.031
Foxp1	forkhead box P1	0.031
Rybp	RING1 and YY1 binding protein	0.031
Vstm2b	V-set and transmembrane domain containing 2B	0.030
Ar	androgen receptor	0.030
Gata2	GATA binding protein 2	0.030
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.030
Bcl6	B-cell leukemia/lymphoma 6	0.029
Bmp5	bone morphogenetic protein 5	0.029
Atoh8	atonal homolog 8 (Drosophila)	0.029
Pou4f2	POU domain, class 4, transcription factor 2	0.029
Prdm6	PR domain containing 6	0.028
Jag1	jagged 1	0.027
Hoxa10	homeobox A10	0.027
Tnfrsf25	tumor necrosis factor receptor superfamily, member 25	0.026
Lhx9	LIM homeobox protein 9	0.026
Vangl2	vang-like 2 (van gogh, Drosophila)	0.026
Snai1	snail homolog 1 (Drosophila)	0.026
Rnf111	ring finger 111	0.025
Otx1	orthodenticle homolog 1 (Drosophila)	0.025
Acvr2a	activin receptor IIA	0.025
Gata4	GATA binding protein 4	0.025
Tdgf1	teratocarcinoma-derived growth factor 1	0.024
Cd44	CD44 antigen	0.024
Elavl2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	0.024
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.024
Myo7a	myosin VIIA	0.024
Socs1	suppressor of cytokine signaling 1	0.024
Sox17	SRY-box containing gene 17	0.024
Hhex	hematopoietically expressed homeobox	0.023
Il6	interleukin 6	0.023
Thbs1	thrombospondin 1	0.023
Yap1	yes-associated protein 1	0.023
Sox9	SRY-box containing gene 9	0.023
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.023
Fgf10	fibroblast growth factor 10	0.022
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.022
Gimap7	GTPase, IMAP family member 7	0.022
Hoxd9	homeobox D9	0.022
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.022
Tead2	TEA domain family member 2	0.022
Shox2	short stature homeobox 2	0.022
Pdcd1	programmed cell death 1	0.021
Ahr	aryl-hydrocarbon receptor	0.021
Nkg7	natural killer cell group 7 sequence	0.021
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.020
Agtr1a	angiotensin II receptor, type 1a	0.020
Mn1	meningioma 1	0.020
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.020
Tbx6	T-box 6	0.020	Mouse
Myo6	myosin VI	0.020
Bmi1	Bmi1 polycomb ring finger oncogene	0.020
Efna1	ephrin A1	0.019
Ptp4a2	protein tyrosine phosphatase 4a2	0.019
Mdm2	transformed mouse 3T3 cell double minute 2	0.019
Nf2	neurofibromatosis 2	0.019
Eomes	eomesodermin homolog (Xenopus laevis)	0.019	Mouse
Runx1	runt related transcription factor 1	0.019
Myf5	myogenic factor 5	0.019
Dlx5	distal-less homeobox 5	0.019
Hoxb4	homeobox B4	0.018
Irx4	Iroquois related homeobox 4 (Drosophila)	0.018
Tgfbr2	transforming growth factor, beta receptor II	0.018
Zfp503	zinc finger protein 503	0.018
Eif4enif1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.018
Brca1	breast cancer 1	0.018
Ccr2	chemokine (C-C motif) receptor 2	0.018
Bcl2	B-cell leukemia/lymphoma 2	0.018
Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	0.018
Prrx1	paired related homeobox 1	0.017
Atr	ataxia telangiectasia and Rad3 related	0.017
Zbtb46	zinc finger and BTB domain containing 46	0.017
Wnk4	WNK lysine deficient protein kinase 4	0.017
Osr1	odd-skipped related 1 (Drosophila)	0.017
Scube2	signal peptide, CUB domain, EGF-like 2	0.017
Tcf7	transcription factor 7, T-cell specific	0.017
Foxc2	forkhead box C2	0.017
Cd5	CD5 antigen	0.017
Ldlr	low density lipoprotein receptor	0.017
Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	0.016
Foxf1a	forkhead box F1a	0.016
Neurog2	neurogenin 2	0.016
Myod1	myogenic differentiation 1	0.016
Msc	musculin	0.016
Gzmk	granzyme K	0.016
Plekha4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.016
Gata6	GATA binding protein 6	0.016
Tnnt3	troponin T3, skeletal, fast	0.016
Klf10	Kruppel-like factor 10	0.015
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.015
Emx2	empty spiracles homolog 2 (Drosophila)	0.015
Tbx21	T-box 21	0.015	Mouse
Xirp1	xin actin-binding repeat containing 1	0.015
6330577E15Rik	RIKEN cDNA 6330577E15 gene	0.015
Apoe	apolipoprotein E	0.015
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.015
Trp73	transformation related protein 73	0.015
Emx1	empty spiracles homolog 1 (Drosophila)	0.015
Tal1	T-cell acute lymphocytic leukemia 1	0.015
Cxadr	coxsackie virus and adenovirus receptor	0.015
Ece1	endothelin converting enzyme 1	0.015
Vmn1r15	vomeronasal 1 receptor 15	0.015
Col4a3	collagen, type IV, alpha 3	0.015
Ntf5	neurotrophin 5	0.015
Runx2	runt related transcription factor 2	0.014
Atp1b4	ATPase, (Na+)/K+ transporting, beta 4 polypeptide	0.014
4933427G17Rik	RIKEN cDNA 4933427G17 gene	0.014
C80913	expressed sequence C80913	0.014
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.014
Gdf3	growth differentiation factor 3	0.014
Nkd1	naked cuticle 1 homolog (Drosophila)	0.014
Sim2	single-minded homolog 2 (Drosophila)	0.014
Fign	fidgetin	0.014
Smad5	MAD homolog 5 (Drosophila)	0.014
Egflam	EGF-like, fibronectin type III and laminin G domains	0.014
Thsd1	thrombospondin, type I, domain 1	0.014
Klf3	Kruppel-like factor 3 (basic)	0.014
Golga5	golgi autoantigen, golgin subfamily a, 5	0.014
Ncoa3	nuclear receptor coactivator 3	0.014
Otop1	otopetrin 1	0.014
Mrfap1	Morf4 family associated protein 1	0.014
Acvr2b	activin receptor IIB	0.014
Ank	progressive ankylosis	0.014
Fasl	Fas ligand (TNF superfamily, member 6)	0.014
Gm12824	predicted gene 12824	0.014
Fam89a	family with sequence similarity 89, member A	0.014
Hif1a	hypoxia inducible factor 1, alpha subunit	0.014
Ryr2	ryanodine receptor 2, cardiac	0.014
Asb12	ankyrin repeat and SOCS box-containing 12	0.014
Wnt2	wingless-related MMTV integration site 2	0.013
Cd8b1	CD8 antigen, beta chain 1	0.013
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.013
Zic1	zinc finger protein of the cerebellum 1	0.013
Chuk	conserved helix-loop-helix ubiquitous kinase	0.013
March6	membrane-associated ring finger (C3HC4) 6	0.013
Vhl	von Hippel-Lindau tumor suppressor	0.013
Tnfaip1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.013
Sox7	SRY-box containing gene 7	0.013
Nckap5l	NCK-associated protein 5-like	0.013
Lhx1	LIM homeobox protein 1	0.013
Trp53	transformation related protein 53	0.013
Mixl1	Mix1 homeobox-like 1 (Xenopus laevis)	0.013
Rora	RAR-related orphan receptor alpha	0.013
Nf1	neurofibromatosis 1	0.013
Kremen1	kringle containing transmembrane protein 1	0.013
Lpar3	lysophosphatidic acid receptor 3	0.013
Dscaml1	Down syndrome cell adhesion molecule-like 1	0.013
Irx5	Iroquois related homeobox 5 (Drosophila)	0.013
Hoxa13	homeobox A13	0.013
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.013
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.013
Nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.013
Pax3	paired box gene 3	0.013
BC020535	cDNA sequence BC020535	0.012
Gbx2	gastrulation brain homeobox 2	0.012
Padi3	peptidyl arginine deiminase, type III	0.012
Mll2	myeloid/lymphoid or mixed-lineage leukemia 2	0.012
Mecom	MDS1 and EVI1 complex locus	0.012
Tnfsf11	tumor necrosis factor (ligand) superfamily, member 11	0.012
Edar	ectodysplasin-A receptor	0.012
Tbx20	T-box 20	0.012
Rragc	Ras-related GTP binding C	0.012
Asb10	ankyrin repeat and SOCS box-containing 10	0.012
Tcra	T-cell receptor alpha chain	0.012
Kiss1r	KISS1 receptor	0.012
Nxf7	nuclear RNA export factor 7	0.012
Rtn4	reticulon 4	0.012
Hmga2	high mobility group AT-hook 2	0.012
Lyz2	lysozyme 2	0.012
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.012
Pou4f1	POU domain, class 4, transcription factor 1	0.012
Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	0.012
Sorbs3	sorbin and SH3 domain containing 3	0.012
Wnt3a	wingless-related MMTV integration site 3A	0.012
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.012
Egr1	early growth response 1	0.012
Traf6	TNF receptor-associated factor 6	0.012
Bmp6	bone morphogenetic protein 6	0.012
She	src homology 2 domain-containing transforming protein E	0.012
Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.012
Aldh1a3	aldehyde dehydrogenase family 1, subfamily A3	0.012
Fgf8	fibroblast growth factor 8	0.012
Bach1	BTB and CNC homology 1	0.012
Tcfcp2l1	transcription factor CP2-like 1	0.012
Hoxb2	homeobox B2	0.012
Adrb1	adrenergic receptor, beta 1	0.012
Lsm14b	LSM14 homolog B (SCD6, S. cerevisiae)	0.012
Fgf13	fibroblast growth factor 13	0.012
Piwil1	piwi-like homolog 1 (Drosophila)	0.012
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.012
Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	0.011
Bmp2	bone morphogenetic protein 2	0.011
Acan	aggrecan	0.011
Vdac2	voltage-dependent anion channel 2	0.011
Ush1g	Usher syndrome 1G homolog (human)	0.011
Cdx2	caudal type homeobox 2	0.011
Npr3	natriuretic peptide receptor 3	0.011
Sftpa1	surfactant associated protein A1	0.011
Card10	caspase recruitment domain family, member 10	0.011
Mbtd1	mbt domain containing 1	0.011
Cbfb	core binding factor beta	0.011
Pparg	peroxisome proliferator activated receptor gamma	0.011
Pax7	paired box gene 7	0.011
Gm1971	predicted gene 1971	0.011
Pou4f3	POU domain, class 4, transcription factor 3	0.011
Pknox1	Pbx/knotted 1 homeobox	0.011
Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	0.011
Themis	thymocyte selection associated	0.011
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.011
Vegfa	vascular endothelial growth factor A	0.011
B9d2	B9 protein domain 2	0.011
Cxcr6	chemokine (C-X-C motif) receptor 6	0.011
Spp1	secreted phosphoprotein 1	0.011
Cd27	CD27 antigen	0.011
Fzd6	frizzled homolog 6 (Drosophila)	0.011
Espn	espin	0.011
Cyp1a1	cytochrome P450, family 1, subfamily a, polypeptide 1	0.011
Foxa1	forkhead box A1	0.011
Wnt9a	wingless-type MMTV integration site 9A	0.011
Pcdhb6	protocadherin beta 6	0.011
Wwc2	WW, C2 and coiled-coil domain containing 2	0.011
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.011
Rspo1	R-spondin homolog (Xenopus laevis)	0.011
Hes7	hairy and enhancer of split 7 (Drosophila)	0.011
Sox18	SRY-box containing gene 18	0.011
Alx3	aristaless-like homeobox 3	0.011
Actr3	ARP3 actin-related protein 3 homolog (yeast)	0.010
Gsc	goosecoid homeobox	0.010
Fgf18	fibroblast growth factor 18	0.010
Ripply3	ripply3 homolog (zebrafish)	0.010
Ren1	renin 1 structural	0.010
Defb10	defensin beta 10	0.010
Tas2r105	taste receptor, type 2, member 105	0.010
Cd28	CD28 antigen	0.010
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.010
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.010
Lats1	large tumor suppressor	0.010
Tlx3	T-cell leukemia, homeobox 3	0.010
Gli3	GLI-Kruppel family member GLI3	0.010
Hic2	hypermethylated in cancer 2	0.010
Slc27a3	solute carrier family 27 (fatty acid transporter), member 3	0.010
Ifrd1	interferon-related developmental regulator 1	0.010
Prdm1	PR domain containing 1, with ZNF domain	0.010
Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	0.010
March5	membrane-associated ring finger (C3HC4) 5	0.010
Ushbp1	Usher syndrome 1C binding protein 1	0.010
Tsc1	tuberous sclerosis 1	0.010
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.010
Phf13	PHD finger protein 13	0.010
4930544G11Rik	RIKEN cDNA 4930544G11 gene	0.010
Flnc	filamin C, gamma	0.010
Prx	periaxin	0.010
Col23a1	collagen, type XXIII, alpha 1	0.010
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.010
Rab5a	RAB5A, member RAS oncogene family	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010
Npy2r	neuropeptide Y receptor Y2	0.010
Cbln3	cerebellin 3 precursor protein	0.010
Dmtf1	cyclin D binding myb-like transcription factor 1	0.010