The network for 'regulation of transmembrane receptor protein serine threonine kinase signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transmembrane receptor protein serine threonine kinase signaling pathway

Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.

Homo sapiens
Name Description Probability Func Analog Organism
SMAD7 SMAD family member 7 1.000
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
SMAD3 SMAD family member 3 1.000
SMAD2 SMAD family member 2 0.996
FHL2 four and a half LIM domains 2 0.996
CREBBP CREB binding protein 0.996
SMAD4 SMAD family member 4 0.995
SMAD1 SMAD family member 1 0.992
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.987
TGFB1 transforming growth factor, beta 1 0.980
TP53 tumor protein p53 0.979
FN1 fibronectin 1 0.977
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.973
SKIL SKI-like oncogene 0.953
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.949
SMAD5 SMAD family member 5 0.937
TGFBR1 transforming growth factor, beta receptor 1 0.923
BMPR1A bone morphogenetic protein receptor, type IA 0.884
PML promyelocytic leukemia 0.853
SIRT1 sirtuin 1 0.768
SNX6 sorting nexin 6 0.762
SP1 Sp1 transcription factor 0.759
PAX3 paired box 3 0.752
ATXN1 ataxin 1 0.736
FSTL1 follistatin-like 1 0.688
EP300 E1A binding protein p300 0.634
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.634
ZFYVE9 zinc finger, FYVE domain containing 9 0.605
SNTA1 syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) 0.600
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.594
JAG1 jagged 1 0.554
FBLN1 fibulin 1 0.551
LRP6 low density lipoprotein receptor-related protein 6 0.545
TGFB3 transforming growth factor, beta 3 0.538
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.523
YAP1 Yes-associated protein 1 0.520
ENG endoglin 0.511
TBX5 T-box 5 0.506
BMP2 bone morphogenetic protein 2 0.472
PTK2 PTK2 protein tyrosine kinase 2 0.435
NRP1 neuropilin 1 0.422
CXXC5 CXXC finger protein 5 0.400
AR androgen receptor 0.399
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.391
SKI v-ski sarcoma viral oncogene homolog (avian) 0.388
LOX lysyl oxidase 0.383
FOXD3 forkhead box D3 0.371
MAGEF1 melanoma antigen family F, 1 0.365
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.364
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.352
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.351
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.351
RNF11 ring finger protein 11 0.350
TGFB2 transforming growth factor, beta 2 0.333
ADRB1 adrenergic, beta-1-, receptor 0.333
ABI2 abl-interactor 2 0.325
SNX1 sorting nexin 1 0.322
SMAD6 SMAD family member 6 0.321
PIAS4 protein inhibitor of activated STAT, 4 0.317
TIMP3 TIMP metallopeptidase inhibitor 3 0.317
BMP1 bone morphogenetic protein 1 0.312
IGFBP5 insulin-like growth factor binding protein 5 0.303
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.302
TPBG trophoblast glycoprotein 0.297
INHBA inhibin, beta A 0.284
COL1A1 collagen, type I, alpha 1 0.270
PARVA parvin, alpha 0.263
COL8A1 collagen, type VIII, alpha 1 0.263
LIN7B lin-7 homolog B (C. elegans) 0.258
BMPR1B bone morphogenetic protein receptor, type IB 0.252
NCOR1 nuclear receptor corepressor 1 0.244
NOTCH1 notch 1 0.243
PIAS1 protein inhibitor of activated STAT, 1 0.242
ACVR1 activin A receptor, type I 0.233
MIB1 mindbomb homolog 1 (Drosophila) 0.233
CTGF connective tissue growth factor 0.222
BMP7 bone morphogenetic protein 7 0.221
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.220
SIAH1 seven in absentia homolog 1 (Drosophila) 0.216
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.212
WRN Werner syndrome, RecQ helicase-like 0.211
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.200
INSR insulin receptor 0.197
PXN paxillin 0.195
THBS1 thrombospondin 1 0.194
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.190
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.188
CALD1 caldesmon 1 0.186
HIC1 hypermethylated in cancer 1 0.185
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.184
TRIM33 tripartite motif containing 33 0.183
ADAM12 ADAM metallopeptidase domain 12 0.183
POU3F2 POU class 3 homeobox 2 0.179
EPAS1 endothelial PAS domain protein 1 0.172
CAV1 caveolin 1, caveolae protein, 22kDa 0.172
TP53BP2 tumor protein p53 binding protein, 2 0.169
ELN elastin 0.164
DCN decorin 0.159
HEYL hairy/enhancer-of-split related with YRPW motif-like 0.155
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
daf-11 Protein DAF-11 0.528
unc-9 Protein UNC-9 0.144
egl-18 Protein EGL-18 0.134
cat-1 Protein CAT-1 0.102
daf-4 Protein DAF-4 0.099
pkg-1 Protein PKG-1 0.069
osm-6 Protein OSM-6 0.066
sel-8 Protein SEL-8 0.056
daf-1 Protein DAF-1 0.055
tag-320 Protein TAG-320 0.054
pry-1 Protein PRY-1 0.040
R10E4.1 Protein R10E4.1 0.039
unc-73 Protein UNC-73 0.038
tax-4 Protein TAX-4 0.033
osm-5 Protein OSM-5 0.033
eat-4 Protein EAT-4 0.032
rig-6 Protein RIG-6 0.030
nhr-67 Protein NHR-67 0.030
daf-2 Protein DAF-2 0.029
pha-4 Protein PHA-4 0.029
gcy-22 Protein GCY-22 0.028
osm-3 Protein OSM-3 0.028
bli-1 Protein BLI-1 0.027
igdb-2 Protein IGDB-2 0.027
apm-3 Protein APM-3 0.027
odr-3 Protein ODR-3 0.027
daf-3 Protein DAF-3 0.024
R05G6.10 Protein R05G6.10 0.023
skn-1 Protein SKN-1 0.023
vab-8 Protein VAB-8 0.022
scrm-1 Protein SCRM-1 0.022
abl-1 Protein ABL-1 0.022
bar-1 Protein BAR-1 0.022
lin-25 Protein LIN-25 0.021
ncam-1 Protein NCAM-1 0.021
eya-1 Protein EYA-1 0.020
C43H6.7 Protein C43H6.7 0.019
egl-46 Protein EGL-46 0.018
alh-13 Protein ALH-13 0.018
che-1 Protein CHE-1 0.018
noah-1 Protein NOAH-1 0.018
pmk-1 Protein PMK-1 0.017
unc-7 Protein UNC-7 0.017
pqn-62 Protein PQN-62 0.016
daf-12 Protein DAF-12 0.016
daf-10 Protein DAF-10 0.016
vab-3 Protein VAB-3 0.016
pop-1 Protein POP-1 0.015
che-13 Protein CHE-13 0.015
egl-15 Protein EGL-15 0.015
sqt-1 Protein SQT-1 0.014
che-11 Protein CHE-11 0.014
hlh-2 Protein HLH-2 0.013
gei-8 Protein GEI-8 0.013
vang-1 Protein VANG-1 0.013
tag-241 Protein TAG-241 0.013
ztf-19 Protein ZTF-19 0.013
let-756 Protein LET-756 0.013
jmjc-1 Protein JMJC-1 0.013
ttyh-1 Protein TTYH-1 0.013
tmc-2 Protein TMC-2 0.013
unc-18 Protein UNC-18 0.012
grd-1 Protein GRD-1 0.012
CELE_Y46G5A.29 Protein Y46G5A.29 0.012
let-60 Protein LET-60 0.012
unc-43 Protein UNC-43 0.012
dhcr-7 Protein DHCR-7 0.012
F53F10.2 Protein F53F10.2 0.012
unc-112 Protein UNC-112 0.011
unc-6 Protein UNC-6 0.011
itr-1 Protein ITR-1 0.011
uggt-1 Protein UGGT-1 0.011
col-105 Protein COL-105 0.011
lin-59 Protein LIN-59 0.011
F54E12.2 Protein F54E12.2 0.011
pdfr-1 Protein PDFR-1 0.011
col-48 Protein COL-48 0.011
T28F4.1 Protein T28F4.1 0.010
inx-4 Protein INX-4 0.010
W02B8.1 Protein W02B8.1 0.010
gpb-2 Protein GPB-2 0.010
msi-1 Protein MSI-1 0.010
ZC506.1 Protein ZC506.1 0.010
unc-10 Protein UNC-10 0.010
cam-1 Protein CAM-1 0.010
nhr-71 Protein NHR-71 0.010
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Danio rerio
Name Description Probability Func Analog Organism
chd chordin 0.999
bmp2b bone morphogenetic protein 2b 0.984
ntla no tail a 0.964
flh floating head 0.898
cxcr4a chemokine (C-X-C motif) receptor 4a 0.856
bmp2a bone morphogenetic protein 2a 0.820
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.819
gli1 GLI-Kruppel family member 1 0.817
bmp4 bone morphogenetic protein 4 0.793
shha sonic hedgehog a 0.770
spry4 sprouty (Drosophila) homolog 4 0.683
lft1 lefty1 0.678
dusp6 dual specificity phosphatase 6 0.664
ndr2 nodal-related 2 0.642
epha4a eph receptor A4a 0.639
eomesa eomesodermin homolog a 0.623
tbx20 T-box 20 0.588
gsc goosecoid 0.538
dharma dharma 0.537
tbx2b T-box 2b 0.535
rarab retinoic acid receptor, alpha b 0.515
gbx2 gastrulation brain homeo box 2 0.508
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.500
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.496
twist3 twist3 0.462
raraa retinoic acid receptor, alpha a 0.450
hand2 heart and neural crest derivatives expressed transcript 2 0.443
lmo4a LIM domain only 4a 0.436
foxo3b forkhead box O3b 0.436
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.428
lhx2b LIM homeobox 2b 0.422
ctsl1b cathepsin L, 1 b 0.418
tll1 tolloid-like 1 0.413
ephb4b eph receptor B4b 0.395
ptch2 patched 2 0.389
slc25a37 solute carrier family 25, member 37 0.382
nanos3 nanos homolog 3 0.377
gpc4 glypican 4 0.374
col27a1a collagen, type XXVII, alpha 1a 0.356
wnt11r wingless-type MMTV integration site family, member 11, related 0.347
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.342
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.336
eif4e1b eukaryotic translation initiation factor 4e 1b 0.327
tbx16 T-box gene 16 0.321
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.309
tp53bp2 tumor protein p53 binding protein, 2 0.300
tbx1 T-box 1 0.300
pcdh18b protocadherin 18b 0.296
oep one-eyed pinhead 0.295
wnt3a wingless-type MMTV integration site family, member 3A 0.286
dcc deleted in colorectal carcinoma 0.285
dkk1b dickkopf 1b 0.283
vent ventral expressed homeobox 0.280
sox17 SRY-box containing gene 17 0.276
bmp7a bone morphogenetic protein 7a 0.275
hoxa13b homeo box A13b 0.263
wnt8a wingless-type MMTV integration site family, member 8a 0.255
cdh5 cadherin 5 0.254
nkd1 naked cuticle homolog 1 (Drosophila) 0.248
ptpra protein tyrosine phosphatase, receptor type, A 0.247
wnt9b wingless-type MMTV integration site family, member 9B 0.245
fzd8b frizzled homolog 8b 0.243
twist2 twist2 0.235
bmp3 bone morphogenetic protein 3 0.230
hs6st2 heparan sulfate 6-O-sulfotransferase 2 0.227
gli2a GLI-Kruppel family member GLI2a 0.217
hmx1 H6 homeo box 1 0.217
twist1b twist1b 0.211
cdx4 caudal type homeo box transcription factor 4 0.210
bambia BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a 0.210
rasl11b RAS-like, family 11, member B 0.209
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.198
pcdh10b protocadherin 10b 0.195
crabp2a cellular retinoic acid binding protein 2, a 0.195
foxa3 forkhead box A3 0.194
igf1rb insulin-like growth factor 1b receptor 0.194
plod2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.189
tbx6 T-box gene 6 0.188
rarga retinoic acid receptor gamma a 0.184
smo smoothened homolog (Drosophila) 0.184
robo1 roundabout homolog 1 0.177
acvr2a activin receptor IIa 0.170
acvr2b activin receptor IIb 0.169
smad1 MAD homolog 1 (Drosophila) 0.167
fbn2b fibrillin 2b 0.164
rgma RGM domain family, member A 0.162
wnt9a wingless-type MMTV integration site family, member 9A 0.161
fgfr1b fibroblast growth factor receptor 1b 0.156
pwp2h PWP2 periodic tryptophan protein homolog (yeast) 0.155
hdac4 histone deacetylase 4 0.154
hs6st1a heparan sulfate 6-O-sulfotransferase 1a 0.152
hnf1ba HNF1 homeobox Ba 0.151
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.149
bmpr2a bone morphogenetic protein receptor, type II a (serine/threonine kinase) 0.148
nog1 noggin 1 0.146
plcg1 phospholipase C, gamma 1 0.145
sox32 SRY-box containing gene 32 0.145
cdh2 cadherin 2, neuronal 0.145
foxg1a forkhead box G1a 0.140
nog3 noggin 3 0.139
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Drosophila melanogaster
Name Description Probability Func Analog Organism
ci cubitus interruptus 0.994
sog short gastrulation 0.971
Egfr Epidermal growth factor receptor 0.910
Dad Daughters against dpp 0.895
tkv thickveins 0.883
gbb glass bottom boat 0.828
wit wishful thinking 0.788
tld tolloid 0.768
E(spl) Enhancer of split 0.766
Sulf1 Sulfated 0.721
Irk2 Inwardly rectifying potassium channel 2 0.684
N Notch 0.633
Socs36E Suppressor of cytokine signaling at 36E 0.619
EcR Ecdysone receptor 0.611
sax saxophone 0.599
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.599
kek5 kekkon5 0.574
mbc myoblast city 0.563
wun wunen 0.557
tok tolkin 0.546
dm diminutive 0.532
cv-2 crossveinless 2 0.473
fkh fork head 0.437
brk brinker 0.417
dlg1 discs large 1 0.414
kay kayak 0.403
ab abrupt 0.385
dpp decapentaplegic 0.367
Mad Mothers against dpp 0.341
Snoo Sno oncogene 0.338
Dap160 Dynamin associated protein 160 0.317
HLHm7 E(spl) region transcript m7 0.297
robo roundabout 0.292
S6k RPS6-p70-protein kinase 0.273
HLHmdelta E(spl) region transcript mdelta 0.265
sfl sulfateless 0.265
aux auxillin 0.257
CtBP C-terminal Binding Protein 0.254
hep hemipterous 0.248
mys myospheroid 0.243
Sir2 CG5216 gene product from transcript CG5216-RA 0.236
egh egghead 0.236
tll tailless 0.228
ct cut 0.224
Ssdp Sequence-specific single-stranded DNA-binding protein 0.223
coro CG9446 gene product from transcript CG9446-RC 0.219
HLHmbeta E(spl) region transcript mbeta 0.213
Tl Toll 0.209
cv crossveinless 0.200
neuroligin CG13772 gene product from transcript CG13772-RA 0.198
HLHmgamma E(spl) region transcript mgamma 0.187
daw dawdle 0.184
Smox Smad on X 0.183
babo baboon 0.182
ex expanded 0.175
Su(z)2 Suppressor of zeste 2 0.172
Lasp CG3849 gene product from transcript CG3849-RB 0.169
gro groucho 0.161
Atg1 Autophagy-specific gene 1 0.161
HLHm3 E(spl) region transcript m3 0.158
so sine oculis 0.153
Mer Merlin 0.146
zfh2 Zn finger homeodomain 2 0.140
shn schnurri 0.139
htl heartless 0.136
boi brother of iHog 0.134
LamC Lamin C 0.133
unc-104 CG8566 gene product from transcript CG8566-RB 0.131
bib big brain 0.129
Eip93F CG18389 gene product from transcript CG18389-RB 0.125
InR Insulin-like receptor 0.119
zpg zero population growth 0.118
Sdc Syndecan 0.113
comt comatose 0.112
HLHm5 E(spl) region transcript m5 0.112
fng fringe 0.112
Akt1 CG4006 gene product from transcript CG4006-RA 0.112
numb CG3779 gene product from transcript CG3779-RB 0.111
rictor rapamycin-insensitive companion of Tor 0.109
put punt 0.109
Fak56D Focal Adhesion Kinase 0.109
G-oalpha47A G protein oalpha 47A 0.109
tsg twisted gastrulation 0.109
CG3194 CG3194 gene product from transcript CG3194-RB 0.107
CG10200 CG10200 gene product from transcript CG10200-RB 0.106
Su(H) Suppressor of Hairless 0.105
kn knot 0.102
Nf1 Neurofibromin 1 0.100
Pax Paxillin 0.099
CG11347 CG11347 gene product from transcript CG11347-RE 0.096
CG10103 CG10103 gene product from transcript CG10103-RA 0.095
CG9986 CG9986 gene product from transcript CG9986-RA 0.094
hh hedgehog 0.091
alpha-Spec alpha Spectrin 0.090
m2 E(spl) region transcript m2 0.089
sd scalloped 0.088
insc inscuteable 0.088
ds dachsous 0.087
SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit 0.085
CG16884 CG16884 gene product from transcript CG16884-RA 0.084
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Tgfb2 transforming growth factor, beta 2 0.998
Pitx2 paired-like homeodomain transcription factor 2 0.987
Bmp4 bone morphogenetic protein 4 0.979
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.977
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.977
Smad6 MAD homolog 6 (Drosophila) 0.966
Fgfr2 fibroblast growth factor receptor 2 0.966
Acvr1 activin A receptor, type 1 0.966
Nodal nodal 0.958
Shh sonic hedgehog 0.956
Chrd chordin 0.949
Otx2 orthodenticle homolog 2 (Drosophila) 0.940
Smad7 MAD homolog 7 (Drosophila) 0.915
Smad3 MAD homolog 3 (Drosophila) 0.915
Vegfa vascular endothelial growth factor A 0.877
Hoxa1 homeobox A1 0.877
Lef1 lymphoid enhancer binding factor 1 0.854
Fgf8 fibroblast growth factor 8 0.843
Gli3 GLI-Kruppel family member GLI3 0.842
Tcfap2a transcription factor AP-2, alpha 0.824
Alx4 aristaless-like homeobox 4 0.821
Nog noggin 0.811
Sox2 SRY-box containing gene 2 0.810
Tbx3 T-box 3 0.789
Sfrp2 secreted frizzled-related protein 2 0.767
Gdnf glial cell line derived neurotrophic factor 0.759
Prrx2 paired related homeobox 2 0.758
Msx2 homeobox, msh-like 2 0.755
Hes1 hairy and enhancer of split 1 (Drosophila) 0.755
Wnt3a wingless-related MMTV integration site 3A 0.750
Apc adenomatosis polyposis coli 0.747
Snai1 snail homolog 1 (Drosophila) 0.740
Efnb2 ephrin B2 0.737
Tgfbr2 transforming growth factor, beta receptor II 0.724
Fgfr1 fibroblast growth factor receptor 1 0.720
Amhr2 anti-Mullerian hormone type 2 receptor 0.713
Gata4 GATA binding protein 4 0.705
Bmp7 bone morphogenetic protein 7 0.702
Axin1 axin 1 0.697
Rarb retinoic acid receptor, beta 0.670
Cdkn2a cyclin-dependent kinase inhibitor 2A 0.661
Prrx1 paired related homeobox 1 0.656
Pax3 paired box gene 3 0.647
Foxa2 forkhead box A2 0.644
Fst follistatin 0.639
Pten phosphatase and tensin homolog 0.627
Pou5f1 POU domain, class 5, transcription factor 1 0.610
Gata6 GATA binding protein 6 0.589
Smad4 MAD homolog 4 (Drosophila) 0.584
Eng endoglin 0.583
Fgf5 fibroblast growth factor 5 0.561
Tbx1 T-box 1 0.555
Gpc3 glypican 3 0.553
Eya1 eyes absent 1 homolog (Drosophila) 0.550
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.547
Onecut1 one cut domain, family member 1 0.537
Kdr kinase insert domain protein receptor 0.536
Hand1 heart and neural crest derivatives expressed transcript 1 0.533
Foxh1 forkhead box H1 0.525
Grb10 growth factor receptor bound protein 10 0.520
Fgf15 fibroblast growth factor 15 0.514
Ntn1 netrin 1 0.511
Twist2 twist homolog 2 (Drosophila) 0.509
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.507
Fzd1 frizzled homolog 1 (Drosophila) 0.507
Zic3 zinc finger protein of the cerebellum 3 0.506
Mapk14 mitogen-activated protein kinase 14 0.502
Wnt5a wingless-related MMTV integration site 5A 0.500
Cdon cell adhesion molecule-related/down-regulated by oncogenes 0.485
Inhbb inhibin beta-B 0.483
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.480
Ptrf polymerase I and transcript release factor 0.477
Gdf1 growth differentiation factor 1 0.473
Trp63 transformation related protein 63 0.469
Axin2 axin2 0.466
Pou3f3 POU domain, class 3, transcription factor 3 0.466
Ret ret proto-oncogene 0.465
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.458
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.457
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.455
Nkx2-1 NK2 homeobox 1 0.443
Tbx2 T-box 2 0.438
Eda ectodysplasin-A 0.438
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.432
Ctnnb1 catenin (cadherin associated protein), beta 1 0.428
Braf Braf transforming gene 0.428
Gas1 growth arrest specific 1 0.424
Ece1 endothelin converting enzyme 1 0.424
En1 engrailed 1 0.423
Hoxd11 homeobox D11 0.420
Acvrl1 activin A receptor, type II-like 1 0.416
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.414
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.396
Meox2 mesenchyme homeobox 2 0.396
Nkx1-2 NK1 transcription factor related, locus 2 (Drosophila) 0.393
Sox18 SRY-box containing gene 18 0.392
Dlx5 distal-less homeobox 5 0.392
Wnt3 wingless-related MMTV integration site 3 0.392
Thbs1 thrombospondin 1 0.371
Smo smoothened homolog (Drosophila) 0.370
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Lamc1 laminin, gamma 1 0.728
Ece1 endothelin converting enzyme 1 0.601
Pmepa1 prostate transmembrane protein, androgen induced 1 0.493
Flt1 FMS-related tyrosine kinase 1 0.353
Prkch protein kinase C, eta 0.269
Smad7 SMAD family member 7 0.231
Cish cytokine inducible SH2-containing protein 0.219
Mcam melanoma cell adhesion molecule 0.182
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.175
Hes1 hairy and enhancer of split 1 (Drosophila) 0.173
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.165
Pde4a phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) 0.155
Jak2 Janus kinase 2 0.133
Agtr1a angiotensin II receptor, type 1a 0.132
Col4a1 collagen, type IV, alpha 1 0.131
Stat6 signal transducer and activator of transcription 6 0.129
Emp1 epithelial membrane protein 1 0.117
Nos3 nitric oxide synthase 3, endothelial cell 0.111
Gata6 GATA binding protein 6 0.109
Cand1 cullin-associated and neddylation-dissociated 1 0.095
Pecam1 platelet/endothelial cell adhesion molecule 1 0.092
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.067
Efnb1 ephrin B1 0.066
Eng endoglin 0.065
Fbln5 fibulin 5 0.064
Slit3 slit homolog 3 (Drosophila) 0.064
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.058
Akt1s1 AKT1 substrate 1 (proline-rich) 0.056
Ednra endothelin receptor type A 0.054
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.054
Vegfa vascular endothelial growth factor A 0.051
Tgfbr2 transforming growth factor, beta receptor II 0.050
Timp3 TIMP metallopeptidase inhibitor 3 0.049
Col4a4 collagen, type IV, alpha 4 0.048
Timp2 TIMP metallopeptidase inhibitor 2 0.045
LOC100360403 ATP-binding cassette, sub-family C, member 9-like 0.045
Sox17 SRY (sex determining region Y)-box 17 0.042
Pdpn podoplanin 0.042
Smad6 SMAD family member 6 0.041
Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 0.040
Tgfbr3 transforming growth factor, beta receptor III 0.039
Rara retinoic acid receptor, alpha 0.038
Amd1 adenosylmethionine decarboxylase 1 0.036
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.034
Socs2 suppressor of cytokine signaling 2 0.034
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.033
Ddr2 discoidin domain receptor tyrosine kinase 2 0.033
Atp7b ATPase, Cu++ transporting, beta polypeptide 0.032
Met met proto-oncogene 0.029
Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 0.029
Thbd thrombomodulin 0.029
Tp53 tumor protein p53 0.029
Nfia nuclear factor I/A 0.029
Adra2b adrenergic, alpha-2B-, receptor 0.028
Prph2 peripherin 2 0.028
Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 0.028
Myh9 myosin, heavy chain 9, non-muscle 0.028
Hand2 heart and neural crest derivatives expressed 2 0.028
Jub jub, ajuba homolog (Xenopus laevis) 0.028
Impa1 Inositol (myo)-1(or 4)-monophosphatase 1 0.028
Loxl1 lysyl oxidase-like 1 0.027
Fam198b family with sequence similarity 198, member B 0.027
Cdh5 cadherin 5 0.026
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.026
Hsp90b1 heat shock protein 90, beta, member 1 0.025
Tgfb3 transforming growth factor, beta 3 0.025
Hpcal4 hippocalcin-like 4 0.025
Npr3 natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) 0.025
Gsk3b glycogen synthase kinase 3 beta 0.025
Igf2r insulin-like growth factor 2 receptor 0.024
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.024
Gata4 GATA binding protein 4 0.024
Mr1 major histocompatibility complex, class I-related 0.024
Ncan neurocan 0.024
Wt1 Wilms tumor 1 0.023
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.023
Rest RE1-silencing transcription factor 0.023
Dlg4 discs, large homolog 4 (Drosophila) 0.023
Sox7 SRY (sex determining region Y)-box 7 0.023
Foxq1 forkhead box Q1 0.022
Mafb v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) 0.022
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.022
RT1-M4 RT1 class Ib, locus M4 0.022
Fgf1 fibroblast growth factor 1 0.022
Ssbp4 single stranded DNA binding protein 4 0.022
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.022
Qk quaking 0.022
Map3k3 mitogen activated protein kinase kinase kinase 3 0.022
Tceb3 transcription elongation factor B (SIII), polypeptide 3 0.021
Olfml2b olfactomedin-like 2B 0.021
Fgfr2 fibroblast growth factor receptor 2 0.021
Kcnj9 potassium inwardly-rectifying channel, subfamily J, member 9 0.021
Slc12a1 solute carrier family 12 (sodium/potassium/chloride transporters), member 1 0.021
Gja3 gap junction protein, alpha 3 0.020
Klf13 Kruppel-like factor 13 0.020
Epas1 endothelial PAS domain protein 1 0.020
Dlgap2 discs, large (Drosophila) homolog-associated protein 2 0.020
Nox4 NADPH oxidase 4 0.020
Pias2 protein inhibitor of activated STAT, 2 0.019
Nes nestin 0.019
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism