Process View
The network for 'insulin receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Lepr | leptin receptor | 1.000 | |
Insr | insulin receptor | 0.997 | |
Grb2 | growth factor receptor bound protein 2 | 0.993 | |
Fyn | Fyn proto-oncogene | 0.955 | |
Jak2 | Janus kinase 2 | 0.939 | |
Apc | adenomatosis polyposis coli | 0.931 | |
Ghr | growth hormone receptor | 0.927 | |
Cbl | Casitas B-lineage lymphoma | 0.917 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.898 | |
Ptk2 | PTK2 protein tyrosine kinase 2 | 0.895 | |
Per2 | period homolog 2 (Drosophila) | 0.886 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.884 | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.876 | |
Pparg | peroxisome proliferator activated receptor gamma | 0.871 | |
Pik3r1 | phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) | 0.845 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.820 | |
Lep | leptin | 0.819 | |
Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.811 | |
Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.764 | |
Irs2 | insulin receptor substrate 2 | 0.759 | |
Egfr | epidermal growth factor receptor | 0.756 | |
Mup19 | major urinary protein 19 | 0.706 | |
Fas | Fas (TNF receptor superfamily member 6) | 0.626 | |
Pik3ca | phosphatidylinositol 3-kinase, catalytic, alpha polypeptide | 0.625 | |
Nck2 | non-catalytic region of tyrosine kinase adaptor protein 2 | 0.576 | |
Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.539 | |
Npc1 | Niemann Pick type C1 | 0.539 | |
Grb10 | growth factor receptor bound protein 10 | 0.520 | |
Mup10 | major urinary protein 10 | 0.517 | |
Dok1 | docking protein 1 | 0.506 | |
Plcg1 | phospholipase C, gamma 1 | 0.489 | |
Lipe | lipase, hormone sensitive | 0.483 | |
Apoe | apolipoprotein E | 0.483 | |
Igf1r | insulin-like growth factor I receptor | 0.480 | |
LOC100048884 | novel member of the major urinary protein (Mup) gene family | 0.469 | |
Cav1 | caveolin 1, caveolae protein | 0.467 | |
Tek | endothelial-specific receptor tyrosine kinase | 0.418 | |
Tsc1 | tuberous sclerosis 1 | 0.393 | |
Nos1 | nitric oxide synthase 1, neuronal | 0.383 | |
Dok2 | docking protein 2 | 0.354 | |
Blnk | B-cell linker | 0.352 | |
Pnpla2 | patatin-like phospholipase domain containing 2 | 0.342 | |
Akt1 | thymoma viral proto-oncogene 1 | 0.338 | |
Mup5 | major urinary protein 5 | 0.318 | |
Clock | circadian locomotor output cycles kaput | 0.307 | |
Mup4 | major urinary protein 4 | 0.288 | |
Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.277 | |
Kit | kit oncogene | 0.247 | |
Stat3 | signal transducer and activator of transcription 3 | 0.243 | |
Esr1 | estrogen receptor 1 (alpha) | 0.233 | |
Ins2 | insulin II | 0.226 | |
Gab2 | growth factor receptor bound protein 2-associated protein 2 | 0.221 | |
Irs1 | insulin receptor substrate 1 | 0.211 | |
Mup1 | major urinary protein 1 | 0.208 | |
Mup9 | major urinary protein 9 | 0.200 | |
Smarca4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.200 | |
Axin1 | axin 1 | 0.195 | |
Shc1 | src homology 2 domain-containing transforming protein C1 | 0.191 | |
Pim1 | proviral integration site 1 | 0.184 | |
Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.183 | |
Nr1h4 | nuclear receptor subfamily 1, group H, member 4 | 0.180 | |
Tsc2 | tuberous sclerosis 2 | 0.173 | |
Drd2 | dopamine receptor D2 | 0.170 | |
Tnf | tumor necrosis factor | 0.167 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.166 | |
Akr1c6 | aldo-keto reductase family 1, member C6 | 0.164 | |
LOC100048885 | major urinary protein LOC100048885 | 0.163 | |
Mup12 | major urinary protein 12 | 0.161 | |
Rb1 | retinoblastoma 1 | 0.160 | |
Ldb3 | LIM domain binding 3 | 0.158 | |
Cyp2e1 | cytochrome P450, family 2, subfamily e, polypeptide 1 | 0.152 | |
Mup7 | major urinary protein 7 | 0.150 | |
Tgfb1 | transforming growth factor, beta 1 | 0.149 | |
F9 | coagulation factor IX | 0.147 | |
Megf8 | multiple EGF-like-domains 8 | 0.147 | |
Mup11 | major urinary protein 11 | 0.142 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.140 | |
Mup13 | major urinary protein 13 | 0.139 | |
Ep300 | E1A binding protein p300 | 0.137 | |
Gab1 | growth factor receptor bound protein 2-associated protein 1 | 0.137 | |
Agtr1a | angiotensin II receptor, type 1a | 0.137 | |
Ar | androgen receptor | 0.134 | |
Mup2 | major urinary protein 2 | 0.133 | |
Mup17 | major urinary protein 17 | 0.130 | |
Mup8 | major urinary protein 8 | 0.129 | |
Adipoq | adiponectin, C1Q and collagen domain containing | 0.129 | |
Mup14 | major urinary protein 14 | 0.128 | |
Nf2 | neurofibromatosis 2 | 0.126 | |
Kiss1 | KiSS-1 metastasis-suppressor | 0.123 | |
Cyp1a2 | cytochrome P450, family 1, subfamily a, polypeptide 2 | 0.121 | |
Fmr1 | fragile X mental retardation syndrome 1 homolog | 0.119 | |
Il6st | interleukin 6 signal transducer | 0.116 | |
Fgf21 | fibroblast growth factor 21 | 0.116 | |
Epn1 | epsin 1 | 0.113 | |
Sos1 | son of sevenless homolog 1 (Drosophila) | 0.110 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.109 | |
Mup15 | major urinary protein 15 | 0.108 | |
Igf2 | insulin-like growth factor 2 | 0.106 | |
Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.105 | |
Tgfbr1 | transforming growth factor, beta receptor I | 0.105 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
acs-20 | Protein ACS-20 | 0.082 | |
oac-46 | Protein OAC-46 | 0.057 | |
hnd-1 | Protein HND-1 | 0.055 | |
osm-3 | Protein OSM-3 | 0.054 | |
pry-1 | Protein PRY-1 | 0.053 | |
ifg-1 | Protein IFG-1 | 0.052 | |
che-2 | Protein CHE-2 | 0.051 | |
T19A5.3 | Protein T19A5.3 | 0.051 | |
ptr-1 | Protein PTR-1 | 0.050 | |
osm-6 | Protein OSM-6 | 0.049 | |
nhr-67 | Protein NHR-67 | 0.047 | |
ptr-6 | Protein PTR-6 | 0.045 | |
vab-3 | Protein VAB-3 | 0.043 | |
hlh-14 | Protein HLH-14 | 0.043 | |
daf-7 | Protein DAF-7 | 0.042 | |
che-3 | Protein CHE-3 | 0.037 | |
ptr-11 | Protein PTR-11 | 0.037 | |
F28H7.8 | Protein F28H7.8 | 0.034 | |
CELE_C01G6.5 | Protein C01G6.5 | 0.033 | |
K02A6.2 | Protein K02A6.2 | 0.031 | |
Y113G7C.1 | Protein Y113G7C.1 | 0.030 | |
C52A10.1 | Protein C52A10.1 | 0.029 | |
T25F10.3 | Protein T25F10.3 | 0.027 | |
CELE_C27D8.2 | Protein C27D8.2 | 0.026 | |
nhr-50 | Protein NHR-50 | 0.026 | |
C34E7.4 | Protein C34E7.4 | 0.025 | |
unc-104 | Protein UNC-104 | 0.025 | |
qua-1 | Protein QUA-1 | 0.024 | |
C06E8.5 | Protein C06E8.5 | 0.024 | |
CELE_M05D6.3 | Protein M05D6.3 | 0.023 | |
osm-5 | Protein OSM-5 | 0.022 | |
CELE_Y47G6A.13 | Protein Y47G6A.13 | 0.022 | |
wht-4 | Protein WHT-4 | 0.022 | |
mec-2 | Protein MEC-2 | 0.022 | |
ptr-15 | Protein PTR-15 | 0.021 | |
R11A8.7 | Protein R11A8.7 | 0.020 | |
inx-4 | Protein INX-4 | 0.020 | |
daf-2 | Protein DAF-2 | 0.020 | |
che-1 | Protein CHE-1 | 0.018 | |
osm-1 | Protein OSM-1 | 0.018 | |
CELE_Y11D7A.9 | Protein Y11D7A.9 | 0.018 | |
F42G4.6 | Protein F42G4.6 | 0.018 | |
sms-1 | Protein SMS-1 | 0.017 | |
pde-2 | Protein PDE-2 | 0.017 | |
F36H9.5 | Protein F36H9.5 | 0.017 | |
R05G6.9 | Protein R05G6.9 | 0.016 | |
ina-1 | Protein INA-1 | 0.016 | |
hlh-30 | Protein HLH-30 | 0.016 | |
F38A5.6 | Protein F38A5.6 | 0.016 | |
T05A8.3 | Protein T05A8.3 | 0.016 | |
hmg-1.2 | Protein HMG-1.2 | 0.016 | |
ccch-1 | Protein CCCH-1 | 0.016 | |
acy-3 | Protein ACY-3 | 0.016 | |
F14F11.2 | Protein F14F11.2 | 0.015 | |
zyg-11 | Protein ZYG-11 | 0.015 | |
acc-4 | Protein ACC-4 | 0.015 | |
F54D1.6 | Protein F54D1.6 | 0.015 | |
F56D2.5 | Protein F56D2.5 | 0.014 | |
math-32 | Protein MATH-32 | 0.014 | |
hlh-2 | Protein HLH-2 | 0.014 | |
nas-38 | Protein NAS-38 | 0.014 | |
CELE_Y51A2D.8 | Protein Y51A2D.8 | 0.014 | |
Y38F1A.8 | Protein Y38F1A.8 | 0.014 | |
ZC373.4 | Protein ZC373.4 | 0.014 | |
nfm-1 | Protein NFM-1 | 0.014 | |
bli-3 | Protein BLI-3 | 0.013 | |
sel-10 | Protein SEL-10 | 0.013 | |
C34C6.3 | Protein C34C6.3 | 0.013 | |
che-13 | Protein CHE-13 | 0.013 | |
nhx-9 | Protein NHX-9 | 0.013 | |
M70.3 | Protein M70.3 | 0.013 | |
che-11 | Protein CHE-11 | 0.013 | |
atg-18 | Protein ATG-18 | 0.013 | |
C56C10.4 | Protein C56C10.4 | 0.013 | |
CELE_ZK337.2 | Protein ZK337.2 | 0.013 | |
C47D2.1 | Protein C47D2.1 | 0.013 | |
CELE_Y41C4A.6 | Protein Y41C4A.6 | 0.013 | |
lin-32 | Protein LIN-32 | 0.013 | |
egl-20 | Protein EGL-20 | 0.013 | |
D2024.4 | Protein D2024.4 | 0.013 | |
srp-6 | Protein SRP-6 | 0.012 | |
wrt-1 | Protein WRT-1 | 0.012 | |
D2096.9 | Protein D2096.9 | 0.012 | |
K03E6.7 | Protein K03E6.7 | 0.012 | |
CELE_F07G6.8 | Protein F07G6.8 | 0.012 | |
lgc-27 | Protein LGC-27 | 0.012 | |
CELE_R10D12.1 | Protein R10D12.1 | 0.012 | |
flt-1 | Protein FLT-1 | 0.012 | |
K02G10.5 | Protein K02G10.5 | 0.012 | |
pes-1 | Protein PES-1 | 0.012 | |
T22C8.6 | Protein T22C8.6 | 0.012 | |
C18A3.4 | Protein C18A3.4 | 0.012 | |
CELE_R05A10.4 | Protein R05A10.4 | 0.012 | |
K07A3.3 | Protein K07A3.3 | 0.011 | |
paqr-3 | Protein PAQR-3 | 0.011 | |
tpa-1 | Protein TPA-1 | 0.011 | |
F10E9.2 | Protein F10E9.2 | 0.011 | |
dyf-13 | Protein DYF-13 | 0.011 | |
lpr-3 | Protein LPR-3 | 0.011 | |
CELE_F35E12.9 | Protein F35E12.9 | 0.011 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Ilp2 | Insulin-like peptide 2 | 0.782 | |
Ilp6 | Insulin-like peptide 6 | 0.483 | |
Ras85D | Ras oncogene at 85D | 0.468 | |
Ilp5 | Insulin-like peptide 5 | 0.461 | |
S6k | RPS6-p70-protein kinase | 0.417 | |
B4 | CG9239 gene product from transcript CG9239-RA | 0.402 | |
Mad | Mothers against dpp | 0.401 | |
Pi3K92E | CG4141 gene product from transcript CG4141-RB | 0.396 | |
InR | Insulin-like receptor | 0.346 | |
Pten | CG5671 gene product from transcript CG5671-RB | 0.316 | |
path | pathetic | 0.280 | |
Lnk | CG17367 gene product from transcript CG17367-RC | 0.270 | |
sNPF-R | short neuropeptide F receptor | 0.262 | |
dm | diminutive | 0.234 | |
pico | CG11940 gene product from transcript CG11940-RA | 0.212 | |
Pk61C | Protein kinase 61C | 0.208 | |
Gycalpha99B | Guanylyl cyclase alpha-subunit at 99B | 0.171 | |
ttm50 | tiny tim 50 | 0.144 | |
Ilp3 | Insulin-like peptide 3 | 0.126 | |
Ide | Insulin degrading metalloproteinase | 0.125 | |
jeb | jelly belly | 0.102 | |
boss | bride of sevenless | 0.096 | |
skpA | CG16983 gene product from transcript CG16983-RD | 0.088 | |
CG14815 | CG14815 gene product from transcript CG14815-RA | 0.082 | |
Cyp6t3 | CG8457 gene product from transcript CG8457-RA | 0.079 | |
Gsc | Goosecoid | 0.076 | |
BHD | Birt-Hogg-Dube homolog | 0.072 | |
kis | kismet | 0.069 | |
Hrs | Hepatocyte growth factor regulated tyrosine kinase substrate | 0.069 | |
gig | gigas | 0.067 | |
Indy | I'm not dead yet | 0.065 | |
Ilp7 | Insulin-like peptide 7 | 0.064 | |
Pdp1 | PAR-domain protein 1 | 0.062 | |
sNPF | short neuropeptide F precursor | 0.061 | |
Atg8a | Autophagy-specific gene 8a | 0.058 | |
foxo | forkhead box, sub-group O | 0.058 | |
Atg1 | Autophagy-specific gene 1 | 0.055 | |
spi | spitz | 0.054 | |
Pi3K59F | Phosphotidylinositol 3 kinase 59F | 0.053 | |
CG8443 | CG8443 gene product from transcript CG8443-RA | 0.049 | |
SNF1A | SNF1A/AMP-activated protein kinase | 0.049 | |
Fatp | Fatty acid (long chain) transport protein | 0.047 | |
Myo31DF | Myosin 31DF | 0.045 | |
Tor | Target of rapamycin | 0.043 | |
rictor | rapamycin-insensitive companion of Tor | 0.042 | |
hpo | hippo | 0.041 | |
Su(dx) | Suppressor of deltex | 0.039 | |
daw | dawdle | 0.039 | |
Pde1c | Phosphodiesterase 1c | 0.038 | |
Bre1 | CG10542 gene product from transcript CG10542-RA | 0.037 | |
p38b | CG7393 gene product from transcript CG7393-RA | 0.037 | |
Ptth | Prothoracicotropic hormone | 0.036 | |
sav | salvador | 0.035 | |
slif | slimfast | 0.034 | |
CG3837 | CG3837 gene product from transcript CG3837-RA | 0.032 | |
ImpL2 | Ecdysone-inducible gene L2 | 0.032 | |
Itp-r83A | Inositol 1,4,5,-tris-phosphate receptor | 0.031 | |
melt | melted | 0.031 | |
trp | transient receptor potential | 0.031 | |
tok | tolkin | 0.031 | |
Rheb | CG1081 gene product from transcript CG1081-RA | 0.031 | |
scyl | scylla | 0.030 | |
Vinc | Vinculin | 0.029 | |
Akt1 | CG4006 gene product from transcript CG4006-RA | 0.029 | |
Thor | CG8846 gene product from transcript CG8846-RA | 0.029 | |
cdi | center divider | 0.028 | |
raptor | CG4320 gene product from transcript CG4320-RA | 0.028 | |
HLH106 | Helix loop helix protein 106 | 0.027 | |
Hcf | Host cell factor | 0.027 | |
CycG | Cyclin G | 0.027 | |
Ilp4 | Insulin-like peptide 4 | 0.026 | |
Klp64D | Kinesin-like protein at 64D | 0.026 | |
CG14059 | CG14059 gene product from transcript CG14059-RB | 0.025 | |
ssh | slingshot | 0.025 | |
chrb | charybde | 0.024 | |
RanBPM | Ran-binding protein M | 0.024 | |
CG4221 | CG4221 gene product from transcript CG4221-RA | 0.024 | |
Nf1 | Neurofibromin 1 | 0.024 | |
Art3 | Arginine methyltransferase 3 | 0.024 | |
Dab | Disabled | 0.023 | |
trpl | trp-like | 0.023 | |
ns3 | nucleostemin 3 | 0.023 | |
rols | rolling pebbles | 0.022 | |
didum | dilute class unconventional myosin | 0.022 | |
slik | Sterile20-like kinase | 0.022 | |
pasha | partner of drosha | 0.022 | |
Spt5 | CG7626 gene product from transcript CG7626-RA | 0.022 | |
mtt | mangetout | 0.022 | |
Pigment-dispersing factor | 0.021 | ||
VhaSFD | Vacuolar H[+]-ATPase SFD subunit | 0.020 | |
Nrt | Neurotactin | 0.020 | |
unk | unkempt | 0.020 | |
sev | sevenless | 0.020 | |
nct | nicastrin | 0.020 | |
Lsd-2 | Lipid storage droplet-2 | 0.020 | |
ninaC | neither inactivation nor afterpotential C | 0.019 | |
Trxr-1 | Thioredoxin reductase-1 | 0.019 | |
klg | klingon | 0.019 | |
drk | downstream of receptor kinase | 0.019 | |
Vmat | Vesicular monoamine transporter | 0.019 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 1.000 | |
GRB2 | growth factor receptor-bound protein 2 | 1.000 | |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.994 | |
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.992 | |
INSR | insulin receptor | 0.988 | |
EGFR | epidermal growth factor receptor | 0.963 | |
CREBBP | CREB binding protein | 0.949 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.933 | |
GRB10 | growth factor receptor-bound protein 10 | 0.866 | |
NCOA1 | nuclear receptor coactivator 1 | 0.859 | |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.768 | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.762 | |
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.752 | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.616 | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.588 | |
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.575 | |
NCF1 | neutrophil cytosolic factor 1 | 0.558 | |
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.523 | |
PLCG1 | phospholipase C, gamma 1 | 0.492 | |
GSK3B | glycogen synthase kinase 3 beta | 0.475 | |
MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.455 | |
FYN | FYN oncogene related to SRC, FGR, YES | 0.451 | |
IRS2 | insulin receptor substrate 2 | 0.406 | |
JAK2 | Janus kinase 2 | 0.317 | |
GHR | growth hormone receptor | 0.300 | |
NCOA2 | nuclear receptor coactivator 2 | 0.282 | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.277 | |
PRKCA | protein kinase C, alpha | 0.237 | |
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.224 | |
PRKCZ | protein kinase C, zeta | 0.218 | |
SORBS3 | sorbin and SH3 domain containing 3 | 0.206 | |
CUL1 | cullin 1 | 0.188 | |
IRS1 | insulin receptor substrate 1 | 0.179 | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.175 | |
RXRA | retinoid X receptor, alpha | 0.163 | |
NCK1 | NCK adaptor protein 1 | 0.150 | |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.143 | |
EP300 | E1A binding protein p300 | 0.141 | |
AR | androgen receptor | 0.139 | |
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.138 | |
RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.122 | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.117 | |
MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.117 | |
KAT2B | K(lysine) acetyltransferase 2B | 0.100 | |
SIRT1 | sirtuin 1 | 0.098 | |
CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.098 | |
NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.095 | |
ESR1 | estrogen receptor 1 | 0.095 | |
SH3RF1 | SH3 domain containing ring finger 1 | 0.091 | |
RARA | retinoic acid receptor, alpha | 0.091 | |
SH2B1 | SH2B adaptor protein 1 | 0.086 | |
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.086 | |
EIF4E | eukaryotic translation initiation factor 4E | 0.081 | |
MAPK14 | mitogen-activated protein kinase 14 | 0.078 | |
POU5F1 | POU class 5 homeobox 1 | 0.078 | |
STAT5B | signal transducer and activator of transcription 5B | 0.076 | |
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.074 | |
NCF2 | neutrophil cytosolic factor 2 | 0.073 | |
EPOR | erythropoietin receptor | 0.072 | |
RPTOR | regulatory associated protein of MTOR, complex 1 | 0.067 | |
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.063 | |
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.062 | |
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.059 | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.058 | |
MAPT | microtubule-associated protein tau | 0.056 | |
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.055 | |
RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.054 | |
MAPK3 | mitogen-activated protein kinase 3 | 0.054 | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.053 | |
STAT5A | signal transducer and activator of transcription 5A | 0.050 | |
BCL3 | B-cell CLL/lymphoma 3 | 0.049 | |
PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.049 | |
CREB1 | cAMP responsive element binding protein 1 | 0.048 | |
RAB6A | RAB6A, member RAS oncogene family | 0.043 | |
SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 | 0.042 | |
SOS1 | son of sevenless homolog 1 (Drosophila) | 0.041 | |
SOCS1 | suppressor of cytokine signaling 1 | 0.039 | |
MED15 | mediator complex subunit 15 | 0.037 | |
PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.037 | |
SMAD3 | SMAD family member 3 | 0.035 | |
IL1R1 | interleukin 1 receptor, type I | 0.035 | |
ZAP70 | zeta-chain (TCR) associated protein kinase 70kDa | 0.034 | |
VAV1 | vav 1 guanine nucleotide exchange factor | 0.033 | |
PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.032 | |
EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 | 0.032 | |
LAT | linker for activation of T cells | 0.032 | |
ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.030 | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.029 | |
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.029 | |
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.028 | |
IGF1R | insulin-like growth factor 1 receptor | 0.027 | |
LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.026 | |
HDAC6 | histone deacetylase 6 | 0.026 | |
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.025 | |
DOCK1 | dedicator of cytokinesis 1 | 0.025 | |
IL1RAP | interleukin 1 receptor accessory protein | 0.025 | |
CSK | c-src tyrosine kinase | 0.025 | |
MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.025 | |
EEF2K | eukaryotic elongation factor-2 kinase | 0.024 | |
SNAP25 | synaptosomal-associated protein, 25kDa | 0.024 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Irs1 | insulin receptor substrate 1 | 0.451 | |
Ptpn6 | protein tyrosine phosphatase, non-receptor type 6 | 0.225 | |
Egfr | epidermal growth factor receptor | 0.220 | |
LOC100363783 | rCG53773-like | 0.185 | |
Vav1 | vav 1 guanine nucleotide exchange factor | 0.104 | |
Inpp5d | inositol polyphosphate-5-phosphatase D | 0.101 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.100 | |
Slc4a2 | solute carrier family 4 (anion exchanger), member 2 | 0.094 | |
Pik3r1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.091 | |
Nfia | nuclear factor I/A | 0.078 | |
Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.076 | |
Metap2 | methionyl aminopeptidase 2 | 0.073 | |
Itgb7 | integrin, beta 7 | 0.069 | |
Sbno2 | strawberry notch homolog 2 (Drosophila) | 0.068 | |
Jak2 | Janus kinase 2 | 0.060 | |
Rara | retinoic acid receptor, alpha | 0.059 | |
Ralgds | ral guanine nucleotide dissociation stimulator | 0.058 | |
Sirpa | signal-regulatory protein alpha | 0.056 | |
Stat3 | signal transducer and activator of transcription 3 | 0.056 | |
Cfp | complement factor properdin | 0.054 | |
Lnpep | leucyl/cystinyl aminopeptidase | 0.052 | |
Cd37 | CD37 molecule | 0.047 | |
Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.047 | |
LOC259246 | alpha-2u globulin PGCL1 | 0.045 | |
Stat6 | signal transducer and activator of transcription 6 | 0.042 | |
Acacb | acetyl-Coenzyme A carboxylase beta | 0.040 | |
Cish | cytokine inducible SH2-containing protein | 0.039 | |
Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.039 | |
Mobkl2a | MOB1, Mps One Binder kinase activator-like 2A (yeast) | 0.038 | |
Ppp1r9b | protein phosphatase 1, regulatory subunit 9B | 0.038 | |
Rnf10 | ring finger protein 10 | 0.037 | |
Slc2a3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.036 | |
Itgam | integrin, alpha M | 0.034 | |
Stat5b | signal transducer and activator of transcription 5B | 0.034 | |
Hist1h1a | histone cluster 1, H1a | 0.034 | |
Cd14 | CD14 molecule | 0.033 | |
Pip4k2a | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.033 | |
Phkg1 | phosphorylase kinase, gamma 1 | 0.032 | |
Agtr1a | angiotensin II receptor, type 1a | 0.032 | |
Dpt | dermatopontin | 0.031 | |
Arrdc1 | arrestin domain containing 1 | 0.030 | |
Ampd1 | adenosine monophosphate deaminase 1 (isoform M) | 0.030 | |
Socs2 | suppressor of cytokine signaling 2 | 0.029 | |
Sirt2 | sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) | 0.029 | |
Wdr6 | WD repeat domain 6 | 0.029 | |
Grb2 | growth factor receptor bound protein 2 | 0.029 | |
Epn1 | Epsin 1 | 0.029 | |
Rgs14 | regulator of G-protein signaling 14 | 0.029 | |
Med25 | mediator complex subunit 25 | 0.028 | |
Gria3 | glutamate receptor, ionotrophic, AMPA 3 | 0.028 | |
Itpr1 | inositol 1,4,5-triphosphate receptor, type 1 | 0.028 | |
Sort1 | sortilin 1 | 0.027 | |
Cd86 | CD86 molecule | 0.027 | |
Lgr4 | leucine-rich repeat-containing G protein-coupled receptor 4 | 0.026 | |
Gpam | glycerol-3-phosphate acyltransferase, mitochondrial | 0.026 | |
Capn6 | calpain 6 | 0.026 | |
Gna12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.026 | |
Fgfr1 | Fibroblast growth factor receptor 1 | 0.026 | |
Smad7 | SMAD family member 7 | 0.025 | |
Irs3 | insulin receptor substrate 3 | 0.025 | |
Hk3 | hexokinase 3 (white cell) | 0.025 | |
Ppard | peroxisome proliferator-activated receptor delta | 0.025 | |
Bcl3 | B-cell CLL/lymphoma 3 | 0.024 | |
Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.024 | |
Slc4a1 | solute carrier family 4 (anion exchanger), member 1 | 0.023 | |
Ptger4 | prostaglandin E receptor 4 (subtype EP4) | 0.023 | |
Ryr2 | ryanodine receptor 2, cardiac | 0.023 | |
S1pr2 | sphingosine-1-phosphate receptor 2 | 0.023 | |
Pkn2 | protein kinase N2 | 0.023 | |
Bcar1 | breast cancer anti-estrogen resistance 1 | 0.023 | |
RGD1359529 | similar to chromosome 1 open reading frame 63 | 0.023 | |
Pik3cd | phosphoinositide-3-kinase, catalytic, delta polypeptide | 0.023 | |
Ptprs | protein tyrosine phosphatase, receptor type, S | 0.022 | |
Egr4 | early growth response 4 | 0.022 | |
Rxra | retinoid X receptor alpha | 0.022 | |
Pyy | peptide YY (mapped) | 0.022 | |
Jak3 | Janus kinase 3 | 0.022 | |
Myh9 | myosin, heavy chain 9, non-muscle | 0.022 | |
Serbp1 | Serpine1 mRNA binding protein 1 | 0.021 | |
RGD1307100 | similar to RIKEN cDNA D630029K19 | 0.021 | |
Map3k11 | mitogen-activated protein kinase kinase kinase 11 | 0.021 | |
Ddr1 | discoidin domain receptor tyrosine kinase 1 | 0.021 | |
Igsf6 | immunoglobulin superfamily, member 6 | 0.021 | |
Sfrs12 | splicing factor, arginine/serine-rich 12 | 0.021 | |
Camk2d | calcium/calmodulin-dependent protein kinase II delta | 0.021 | |
Hoxc4 | homeo box C4 | 0.021 | |
Orai1 | ORAI calcium release-activated calcium modulator 1 | 0.020 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.020 | |
Cugbp2 | CUG triplet repeat, RNA binding protein 2 | 0.020 | |
Ghr | growth hormone receptor | 0.020 | |
Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.020 | |
Ddx46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | 0.020 | |
Fth1 | ferritin, heavy polypeptide 1 | 0.020 | |
Mcpt3 | mast cell peptidase 3 | 0.020 | |
Agxt | alanine-glyoxylate aminotransferase | 0.019 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.019 | |
Tpo | thyroid peroxidase | 0.019 | |
Cmklr1 | chemokine-like receptor 1 | 0.019 | |
Gria2 | glutamate receptor, ionotropic, AMPA 2 | 0.019 | |
Grifin | galectin-related inter-fiber protein | 0.019 |