The network for 'positive regulation of erk1 and erk2 cascade' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of erk1 and erk2 cascade

Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

Mus musculus
Name Description Probability Func Analog Organism
Cd44 CD44 antigen 0.993
Lepr leptin receptor 0.955
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.919
Pten phosphatase and tensin homolog 0.896
Shh sonic hedgehog 0.890
Lyz2 lysozyme 2 0.877
Cbl Casitas B-lineage lymphoma 0.875
Cav1 caveolin 1, caveolae protein 0.871
Vegfa vascular endothelial growth factor A 0.869
Acvr1 activin A receptor, type 1 0.865
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.864
Csf1 colony stimulating factor 1 (macrophage) 0.845
Egfr epidermal growth factor receptor 0.830
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.758
Ptk2 PTK2 protein tyrosine kinase 2 0.751
Ccl2 chemokine (C-C motif) ligand 2 0.745
Plcg1 phospholipase C, gamma 1 0.736
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.732
Prkce protein kinase C, epsilon 0.694
Grb2 growth factor receptor bound protein 2 0.684
Kl klotho 0.676
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.661
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.639
Ghr growth hormone receptor 0.625
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.612
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.606
Fgf10 fibroblast growth factor 10 0.604
Mmp9 matrix metallopeptidase 9 0.583
Bdnf brain derived neurotrophic factor 0.558
Tgfbr2 transforming growth factor, beta receptor II 0.530
C1qa complement component 1, q subcomponent, alpha polypeptide 0.527
H2-Aa histocompatibility 2, class II antigen A, alpha 0.523
Nrp1 neuropilin 1 0.487
Tcf21 transcription factor 21 0.480
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.468
Kdr kinase insert domain protein receptor 0.458
Chrd chordin 0.457
Ednra endothelin receptor type A 0.452
Lmna lamin A 0.449
Fyn Fyn proto-oncogene 0.439
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.438
Raf1 v-raf-leukemia viral oncogene 1 0.433
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.430
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.430
Ccr1 chemokine (C-C motif) receptor 1 0.411
Casp1 caspase 1 0.401
Hoxa1 homeobox A1 0.394
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.390
Tlr2 toll-like receptor 2 0.380
Cd86 CD86 antigen 0.380
Arrb1 arrestin, beta 1 0.374
Cx3cr1 chemokine (C-X3-C) receptor 1 0.371
Dok1 docking protein 1 0.367
Arrb2 arrestin, beta 2 0.360
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.358
Bmp4 bone morphogenetic protein 4 0.352
Ccr2 chemokine (C-C motif) receptor 2 0.350
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.349
Inpp5d inositol polyphosphate-5-phosphatase D 0.348
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.338
Fcgr1 Fc receptor, IgG, high affinity I 0.330
H2-Eb1 histocompatibility 2, class II antigen E beta 0.328
Rdh8 retinol dehydrogenase 8 0.327
Pthlh parathyroid hormone-like peptide 0.320
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.315
Btk Bruton agammaglobulinemia tyrosine kinase 0.301
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.297
Prrx1 paired related homeobox 1 0.297
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.289
Hand2 heart and neural crest derivatives expressed transcript 2 0.289
Cd22 CD22 antigen 0.283
Spry4 sprouty homolog 4 (Drosophila) 0.276
Cybb cytochrome b-245, beta polypeptide 0.265
Src Rous sarcoma oncogene 0.251
Agtr2 angiotensin II receptor, type 2 0.251
C1qc complement component 1, q subcomponent, C chain 0.250
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.250
En1 engrailed 1 0.246
Flt4 FMS-like tyrosine kinase 4 0.244
Lep leptin 0.236
Fgf8 fibroblast growth factor 8 0.227
Braf Braf transforming gene 0.218
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.217
Crhr1 corticotropin releasing hormone receptor 1 0.216
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.215
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.213
Nodal nodal 0.211
Kitl kit ligand 0.207
Nos1 nitric oxide synthase 1, neuronal 0.200
Sykb spleen tyrosine kinase 0.200
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.191
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.190
Fut1 fucosyltransferase 1 0.189
Myd88 myeloid differentiation primary response gene 88 0.187
Plxnd1 plexin D1 0.187
Mrc1 mannose receptor, C type 1 0.184
C3ar1 complement component 3a receptor 1 0.182
Ccl3 chemokine (C-C motif) ligand 3 0.182
Phldb2 pleckstrin homology-like domain, family B, member 2 0.181
Hcls1 hematopoietic cell specific Lyn substrate 1 0.180
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pdgfaa platelet-derived growth factor alpha a 0.817
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.793
bmp4 bone morphogenetic protein 4 0.686
esr1 estrogen receptor 1 0.650
vegfc vascular endothelial growth factor c 0.641
ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a 0.635
nod1 nucleotide-binding oligomerization domain containing 1 0.622
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.601
LOC557072 caspase recruitment domain-containing protein 11-like 0.510
igf1 insulin-like growth factor 1 0.464
sox7 SRY-box containing gene 7 0.446
card14 caspase recruitment domain family, member 14 0.413
pycard PYD and CARD domain containing 0.401
hoxa2b homeo box A2b 0.392
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.388
nrp1a neuropilin 1a 0.384
mapk1 mitogen-activated protein kinase 1 0.375
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.371
podxl podocalyxin-like 0.356
fgf3 fibroblast growth factor 3 0.352
efnb2a ephrin B2a 0.342
bmp7b bone morphogenetic protein 7b 0.329
wls wntless homolog (Drosophila) 0.325
tie2 endothelium-specific receptor tyrosine kinase 2 0.324
nadl1.1 neural adhesion molecule L1.1 0.314
wtip Wilms tumor 1 interacting protein 0.314
tfec transcription factor EC 0.303
pax7b paired box gene 7b 0.285
gpr182 G protein-coupled receptor 182 0.265
gpr126 G protein-coupled receptor 126 0.256
nrp2a neuropilin 2a 0.250
flt4 fms-related tyrosine kinase 4 0.221
vegfaa vascular endothelial growth factor Aa 0.215
safb scaffold attachment factor B 0.211
lpp LIM domain containing preferred translocation partner in lipoma 0.210
arrb2b arrestin, beta 2b 0.208
card9 caspase recruitment domain family, member 9 0.206
pax7a paired box gene 7a 0.201
aplnra apelin receptor a 0.181
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.179
kiss1rb KISS1 receptor b 0.172
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.172
aox3 aldehyde oxidase 3 0.168
hdac4 histone deacetylase 4 0.168
fzd7a frizzled homolog 7a 0.167
sc:d812 sc:d812 0.166
si:ch211-212m21.5 si:ch211-212m21.5 0.164
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.163
si:dkey-236e20.2 si:dkey-236e20.2 0.154
fgf4 fibroblast growth factor 4 0.154
cdon cell adhesion molecule-related/down-regulated by oncogenes 0.152
csf1ra colony stimulating factor 1 receptor, a 0.151
nkx2.3 NK2 transcription factor related 3 0.144
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.143
alcama activated leukocyte cell adhesion molecule a 0.143
atp6v0d1 ATPase, H+ transporting, V0 subunit D isoform 1 0.136
vcana versican a 0.132
tie1 endothelium-specific receptor tyrosine kinase 1 0.130
ccm2 cerebral cavernous malformation 2 0.130
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.128
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.128
zgc:112982 zgc:112982 0.121
gdf6a growth differentiation factor 6a 0.120
trnau1apl tRNA selenocysteine 1 associated protein 1, like 0.120
fzd2 frizzled homolog 2 0.119
nog3 noggin 3 0.115
LOC567965 rho GTPase-activating protein 7-like 0.112
krt8 keratin 8 0.111
oprd1a opioid receptor, delta 1a 0.109
notch2 notch homolog 2 0.107
im:7141132 im:7141132 0.107
foxc1a forkhead box C1a 0.105
plagl2 pleiomorphic adenoma gene-like 2 0.105
luc7l LUC7-like (S. cerevisiae) 0.105
drd2b dopamine receptor D2b 0.104
msna moesin a 0.101
cnn2 calponin 2 0.099
kita kit receptor a 0.099
hmx2 H6 family homeobox 2 0.097
uts1 urotensin 1 0.097
pea3 ETS-domain transcription factor pea3 0.096
apom apolipoprotein M 0.095
bnc2 basonuclin 2 0.095
slc25a22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.095
rnd3a Rho family GTPase 3a 0.094
fzd3a frizzled homolog 3a 0.094
xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 0.093
cpne1 copine I 0.093
col14a1 collagen, type XIV, alpha 1 0.093
lndc1 ly6/neurotoxin domain containing 1 0.092
clec14a C-type lectin domain family 14, member A 0.090
hoxa1a homeo box A1a 0.090
vtg6 vitellogenin 6 0.089
si:dkey-181m9.9 si:dkey-181m9.9 0.088
itga2b integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B) 0.087
calm1a calmodulin 1a 0.086
atoh1b atonal homolog 1b 0.085
zgc:112018 zgc:112018 0.085
pmela premelanosome protein a 0.085
mc4r melanocortin 4 receptor 0.084
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.673
phl pole hole 0.581
drk downstream of receptor kinase 0.401
rl rolled 0.310
aop anterior open 0.303
pnut peanut 0.254
pnt pointed 0.241
Rcd1 Reduction in Cnn dots 1 0.184
Dsor1 Downstream of raf1 0.174
csw corkscrew 0.136
mtt mangetout 0.134
Taf6 TBP-associated factor 6 0.110
Gap1 GTPase-activating protein 1 0.102
dco discs overgrown 0.101
spi spitz 0.100
Src64B Src oncogene at 64B 0.100
CG7028 CG7028 gene product from transcript CG7028-RA 0.089
l(1)G0232 lethal (1) G0232 0.085
bun bunched 0.084
Stat92E Signal-transducer and activator of transcription protein at 92E 0.083
stumps CG31317 gene product from transcript CG31317-RC 0.082
Pp1alpha-96A Protein phosphatase 1alpha at 96A 0.074
Mrtf Myocardin-related transcription factor 0.071
mbc myoblast city 0.067
Egfr Epidermal growth factor receptor 0.067
Vps35 Vacuolar protein sorting 35 0.065
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.064
CG15436 CG15436 gene product from transcript CG15436-RA 0.062
put punt 0.061
InR Insulin-like receptor 0.061
CG10139 CG10139 gene product from transcript CG10139-RA 0.061
sty sprouty 0.060
Aac11 CG6582 gene product from transcript CG6582-RA 0.057
Bap60 Brahma associated protein 60kD 0.057
Smox Smad on X 0.056
trio CG18214 gene product from transcript CG18214-RA 0.054
Shc SHC-adaptor protein 0.054
Sry-beta Serendipity beta 0.054
aPKC atypical protein kinase C 0.053
Jra Jun-related antigen 0.053
B4 CG9239 gene product from transcript CG9239-RA 0.052
repo reversed polarity 0.052
CG7386 CG7386 gene product from transcript CG7386-RA 0.051
slmb supernumerary limbs 0.051
Lis-1 Lissencephaly-1 0.050
Gug Grunge 0.050
Sry-delta Serendipity delta 0.050
srp serpent 0.050
aux auxillin 0.049
grau grauzone 0.049
Fcp1 CG12252 gene product from transcript CG12252-RA 0.049
Taf12 TBP-associated factor 12 0.048
zfh1 Zn finger homeodomain 1 0.045
ths thisbe 0.045
wg wingless 0.045
CG7156 CG7156 gene product from transcript CG7156-RA 0.045
Akt1 CG4006 gene product from transcript CG4006-RA 0.044
CG1024 CG1024 gene product from transcript CG1024-RB 0.043
CstF-64 Cleavage stimulation factor 64 kilodalton subunit 0.042
Fmr1 CG6203 gene product from transcript CG6203-RC 0.042
ttv tout-velu 0.041
14-3-3epsilon CG31196 gene product from transcript CG31196-RA 0.041
mib2 mind bomb 2 0.041
Mad Mothers against dpp 0.041
CG16972 CG16972 gene product from transcript CG16972-RA 0.040
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.039
sr stripe 0.038
Dad Daughters against dpp 0.038
CG4751 CG4751 gene product from transcript CG4751-RA 0.037
svp seven up 0.037
CdsA CDP diglyceride synthetase 0.037
npf neuropeptide F 0.036
fl(2)d female lethal d 0.036
Rbsn-5 Rabenosyn-5 0.036
scb scab 0.035
CG6654 CG6654 gene product from transcript CG6654-RA 0.034
SF1 Splicing factor 1 0.033
pUf68 poly U binding factor 68kD 0.033
Tap42 Two A-associated protein of 42kDa 0.033
gig gigas 0.032
CG13472 CG13472 gene product from transcript CG13472-RA 0.032
Rac2 CG8556 gene product from transcript CG8556-RA 0.031
CG9797 CG9797 gene product from transcript CG9797-RA 0.031
Ced-12 CG5336 gene product from transcript CG5336-RA 0.031
CG8176 CG8176 gene product from transcript CG8176-RD 0.031
Srp54 CG4602 gene product from transcript CG4602-RA 0.030
CG6015 CG6015 gene product from transcript CG6015-RA 0.030
TSG101 tumor suppressor protein 101 0.030
par-6 CG5884 gene product from transcript CG5884-RA 0.030
shn schnurri 0.030
p16-ARC CG9881 gene product from transcript CG9881-RA 0.030
lqf liquid facets 0.030
Pk61C Protein kinase 61C 0.030
Cdk9 Cyclin-dependent kinase 9 0.029
CG4617 CG4617 gene product from transcript CG4617-RA 0.029
CG1792 CG1792 gene product from transcript CG1792-RA 0.029
gek genghis khan 0.029
CG9915 CG9915 gene product from transcript CG9915-RB 0.029
CG31108 CG31108 gene product from transcript CG31108-RA 0.029
rho rhomboid 0.028
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Homo sapiens
Name Description Probability Func Analog Organism
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
EGFR epidermal growth factor receptor 1.000
FGFR2 fibroblast growth factor receptor 2 0.999
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.998
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.997
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.996
CCR5 chemokine (C-C motif) receptor 5 0.995
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.995
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.993
VEGFA vascular endothelial growth factor A 0.993
BCAR1 breast cancer anti-estrogen resistance 1 0.992
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.988
CAV1 caveolin 1, caveolae protein, 22kDa 0.984
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.980
FGF1 fibroblast growth factor 1 (acidic) 0.979
GRB2 growth factor receptor-bound protein 2 0.959
AXL AXL receptor tyrosine kinase 0.951
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.947
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.945
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.943
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.935
SFN stratifin 0.931
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.922
FYN FYN oncogene related to SRC, FGR, YES 0.916
EIF4A3 eukaryotic translation initiation factor 4A3 0.915
MAP2K1 mitogen-activated protein kinase kinase 1 0.901
CCL2 chemokine (C-C motif) ligand 2 0.894
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.876
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.864
LAT linker for activation of T cells 0.861
CCL5 chemokine (C-C motif) ligand 5 0.853
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.851
IL8 interleukin 8 0.846
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.802
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.791
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.772
MET met proto-oncogene (hepatocyte growth factor receptor) 0.770
TRAF1 TNF receptor-associated factor 1 0.768
CCR7 chemokine (C-C motif) receptor 7 0.732
TEK TEK tyrosine kinase, endothelial 0.723
RAP1A RAP1A, member of RAS oncogene family 0.713
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.703
FAS Fas (TNF receptor superfamily, member 6) 0.673
IL6 interleukin 6 (interferon, beta 2) 0.670
SPRR2A small proline-rich protein 2A 0.635
PTEN phosphatase and tensin homolog 0.634
CCL4 chemokine (C-C motif) ligand 4 0.632
SRPK2 SRSF protein kinase 2 0.587
IFNG interferon, gamma 0.584
TNF tumor necrosis factor 0.584
CXCL9 chemokine (C-X-C motif) ligand 9 0.583
PLCG1 phospholipase C, gamma 1 0.565
ADORA2A adenosine A2a receptor 0.559
RALGDS ral guanine nucleotide dissociation stimulator 0.546
BMPR1A bone morphogenetic protein receptor, type IA 0.532
CCR4 chemokine (C-C motif) receptor 4 0.514
CCL22 chemokine (C-C motif) ligand 22 0.501
IGF1R insulin-like growth factor 1 receptor 0.480
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.480
SNIP1 Smad nuclear interacting protein 1 0.478
CXCL2 chemokine (C-X-C motif) ligand 2 0.469
CCL13 chemokine (C-C motif) ligand 13 0.455
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.454
NRP1 neuropilin 1 0.453
FGG fibrinogen gamma chain 0.452
CCL19 chemokine (C-C motif) ligand 19 0.447
PTK2 PTK2 protein tyrosine kinase 2 0.447
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.444
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.444
PECAM1 platelet/endothelial cell adhesion molecule 0.441
FGF10 fibroblast growth factor 10 0.434
NOXA1 NADPH oxidase activator 1 0.423
MAPK3 mitogen-activated protein kinase 3 0.411
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.411
SOS1 son of sevenless homolog 1 (Drosophila) 0.392
CCL8 chemokine (C-C motif) ligand 8 0.391
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.389
CTGF connective tissue growth factor 0.389
LRRC7 leucine rich repeat containing 7 0.388
CCL7 chemokine (C-C motif) ligand 7 0.384
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.382
FGA fibrinogen alpha chain 0.365
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.359
IL2RB interleukin 2 receptor, beta 0.359
ARRB1 arrestin, beta 1 0.351
FGF7 fibroblast growth factor 7 0.351
CDH5 cadherin 5, type 2 (vascular endothelium) 0.345
MAPK1 mitogen-activated protein kinase 1 0.344
ZNF496 zinc finger protein 496 0.343
TTR transthyretin 0.340
CCL3 chemokine (C-C motif) ligand 3 0.340
RXRA retinoid X receptor, alpha 0.337
RET ret proto-oncogene 0.317
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Rattus norvegicus
Name Description Probability Func Analog Organism
Met met proto-oncogene 0.656
Sirpa signal-regulatory protein alpha 0.413
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.358
Ccl4 chemokine (C-C motif) ligand 4 0.320
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.287
Ptafr platelet-activating factor receptor 0.243
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.217
Jak1 Janus kinase 1 0.197
Fgf5 fibroblast growth factor 5 0.194
Mapk1 mitogen activated protein kinase 1 0.182
Gja1 gap junction protein, alpha 1 0.180
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.176
Vcam1 vascular cell adhesion molecule 1 0.174
Socs3 suppressor of cytokine signaling 3 0.150
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.134
Cxcl2 chemokine (C-X-C motif) ligand 2 0.128
Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 0.123
Cdh6 cadherin 6 0.122
Il1b interleukin 1 beta 0.115
Adrb1 adrenergic, beta-1-, receptor 0.114
Fgfr2 fibroblast growth factor receptor 2 0.111
Vav1 vav 1 guanine nucleotide exchange factor 0.106
Il1a interleukin 1 alpha 0.104
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.099
Cd4 Cd4 molecule 0.097
RGD1564664 similar to LOC387763 protein 0.095
Hras Harvey rat sarcoma virus oncogene 0.088
Gnat1 guanine nucleotide binding protein (G protein), alpha transducing 1 0.087
Ccl3 chemokine (C-C motif) ligand 3 0.087
Il2ra interleukin 2 receptor, alpha 0.080
Zg16 zymogen granule protein 16 0.078
Bst1 bone marrow stromal cell antigen 1 0.077
Ptgs2 prostaglandin-endoperoxide synthase 2 0.076
Grk4 G protein-coupled receptor kinase 4 0.075
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.074
Slc5a7 solute carrier family 5 (choline transporter), member 7 0.074
Nrarp Notch-regulated ankyrin repeat protein 0.073
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.069
Itgam integrin, alpha M 0.069
Sstr5 somatostatin receptor 5 0.067
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.066
Tcf4 transcription factor 4 0.065
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.064
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.064
Csf1 colony stimulating factor 1 (macrophage) 0.064
Grm8 glutamate receptor, metabotropic 8 0.064
Cybb cytochrome b-245, beta polypeptide 0.064
Hck hemopoietic cell kinase 0.063
Cfb complement factor B 0.061
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.060
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.059
Sstr1 somatostatin receptor 1 0.059
Nrg1 neuregulin 1 0.059
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.058
Prl prolactin 0.057
Olr1500 olfactory receptor 1500 0.057
Ptprc protein tyrosine phosphatase, receptor type, C 0.057
Il1rap interleukin 1 receptor accessory protein 0.055
Rasgrp1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.055
Klf6 Kruppel-like factor 6 0.054
Tgm1 transglutaminase 1, K polypeptide 0.053
P2rx5 purinergic receptor P2X, ligand-gated ion channel, 5 0.052
Synpo synaptopodin 0.051
Marcks myristoylated alanine rich protein kinase C substrate 0.051
Tgfbr2 transforming growth factor, beta receptor II 0.050
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.049
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.049
Ednra endothelin receptor type A 0.049
Ucn2 urocortin 2 0.049
Hist1h1a histone cluster 1, H1a 0.048
A3galt2 alpha 1,3-galactosyltransferase 2 0.048
Cxcr3 chemokine (C-X-C motif) receptor 3 0.046
Shank2 SH3 and multiple ankyrin repeat domains 2 0.046
Arl11 ADP-ribosylation factor-like 11 0.045
Plxnd1 plexin D1 0.045
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.045
Rho rhodopsin 0.045
Cd83 CD83 molecule 0.045
Acmsd aminocarboxymuconate semialdehyde decarboxylase 0.044
Ctsj cathepsin J 0.044
Ppap2b phosphatidic acid phosphatase type 2B 0.044
Edn1 endothelin 1 0.044
Ednrb endothelin receptor type B 0.044
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.043
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.042
Il4 interleukin 4 0.042
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.042
Jak2 Janus kinase 2 0.041
Inpp5d inositol polyphosphate-5-phosphatase D 0.041
Gfra2 GDNF family receptor alpha 2 0.041
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.041
Plcg2 phospholipase C, gamma 2 0.040
Cxcl10 chemokine (C-X-C motif) ligand 10 0.040
LOC287167 globin, alpha 0.040
Slc24a6 solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 0.040
Runx1 runt-related transcription factor 1 0.040
Gdnf glial cell derived neurotrophic factor 0.039
Cpb1 carboxypeptidase B1 (tissue) 0.039
Gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.039
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.038
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism