IMP

Process View

Mus musculus

16 genes annotated in mouse

Multi-species View

regulation of erbb signaling pathway

GO:1901184

Any process that modulates the frequency, rate or extent of ERBB signaling pathway.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of erbb signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of erbb signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
App	amyloid beta (A4) precursor protein	0.746
Prnp	prion protein	0.746
Psen1	presenilin 1	0.258
Cbl	Casitas B-lineage lymphoma	0.247	Fly
Dlg4	discs, large homolog 4 (Drosophila)	0.234	Fly
Blnk	B-cell linker	0.228
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.190
Egfr	epidermal growth factor receptor	0.175
Src	Rous sarcoma oncogene	0.167
Inpp5d	inositol polyphosphate-5-phosphatase D	0.144
Apc	adenomatosis polyposis coli	0.130
Lepr	leptin receptor	0.130
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.123
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.120
Sh3kbp1	SH3-domain kinase binding protein 1	0.116
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.114
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.114
Ctnnb1	catenin (cadherin associated protein), beta 1	0.113
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.110
Aplp2	amyloid beta (A4) precursor-like protein 2	0.107
Vav2	vav 2 oncogene	0.095
Btk	Bruton agammaglobulinemia tyrosine kinase	0.093
Dab1	disabled homolog 1 (Drosophila)	0.091
Usp8	ubiquitin specific peptidase 8	0.089
Ncor1	nuclear receptor co-repressor 1	0.082
Notch1	Notch gene homolog 1 (Drosophila)	0.078
Smarcc1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.077
Dlg1	discs, large homolog 1 (Drosophila)	0.073	Fly
Grb2	growth factor receptor bound protein 2	0.071	Fly
Dnm1	dynamin 1	0.070
Smad3	MAD homolog 3 (Drosophila)	0.067
Numb	numb gene homolog (Drosophila)	0.062
Notch2	Notch gene homolog 2 (Drosophila)	0.061
Kiss1	KiSS-1 metastasis-suppressor	0.056
Prrx1	paired related homeobox 1	0.056
Mecp2	methyl CpG binding protein 2	0.053
Fgfr2	fibroblast growth factor receptor 2	0.053
L1cam	L1 cell adhesion molecule	0.049
Stam2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.046	Fly
Braf	Braf transforming gene	0.046
Bcar1	breast cancer anti-estrogen resistance 1	0.046
Cd22	CD22 antigen	0.046
Vegfa	vascular endothelial growth factor A	0.044
Fyn	Fyn proto-oncogene	0.042
Grap2	GRB2-related adaptor protein 2	0.041	Fly
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.040
Cpeb3	cytoplasmic polyadenylation element binding protein 3	0.040
Pten	phosphatase and tensin homolog	0.038
Prkce	protein kinase C, epsilon	0.038
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.037
Irs1	insulin receptor substrate 1	0.036
Ncstn	nicastrin	0.034
Gab2	growth factor receptor bound protein 2-associated protein 2	0.033
Tgfa	transforming growth factor alpha	0.033	Human
Ptgs2	prostaglandin-endoperoxide synthase 2	0.032
Twsg1	twisted gastrulation homolog 1 (Drosophila)	0.032
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.031
Ptpra	protein tyrosine phosphatase, receptor type, A	0.030
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.030
Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	0.029	Fly
Itga4	integrin alpha 4	0.029	Mouse
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.028	Fly
Clstn1	calsyntenin 1	0.027
Vav3	vav 3 oncogene	0.027
Mea1	male enhanced antigen 1	0.027
Bdnf	brain derived neurotrophic factor	0.026
Psap	prosaposin	0.026
Npc1	Niemann Pick type C1	0.026
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.026
Prkcd	protein kinase C, delta	0.025
Dll4	delta-like 4 (Drosophila)	0.024
Epb4.1l2	erythrocyte protein band 4.1-like 2	0.024
Nos1	nitric oxide synthase 1, neuronal	0.024
Itgal	integrin alpha L	0.024	Mouse
Fgfr3	fibroblast growth factor receptor 3	0.024
Il6st	interleukin 6 signal transducer	0.024
Kiss1r	KISS1 receptor	0.023
Sos1	son of sevenless homolog 1 (Drosophila)	0.023
Rasgrp1	RAS guanyl releasing protein 1	0.023
Csf1	colony stimulating factor 1 (macrophage)	0.022
Sulf2	sulfatase 2	0.021	Fly
Fzd1	frizzled homolog 1 (Drosophila)	0.021
Hif1a	hypoxia inducible factor 1, alpha subunit	0.021
Fgr	Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog	0.020
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.020
Dlg3	discs, large homolog 3 (Drosophila)	0.020	Fly
Nf1	neurofibromatosis 1	0.020
Vav1	vav 1 oncogene	0.020
Umod	uromodulin	0.020
Ctsb	cathepsin B	0.019
Batf	basic leucine zipper transcription factor, ATF-like	0.019
Itgb3	integrin beta 3	0.019
Jak2	Janus kinase 2	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Arid1a	AT rich interactive domain 1A (SWI-like)	0.018
Pgr	progesterone receptor	0.018
Dlg2	discs, large homolog 2 (Drosophila)	0.018	Fly
Icos	inducible T-cell co-stimulator	0.017
Pdcd1	programmed cell death 1	0.017
Acvr1	activin A receptor, type 1	0.017
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.017
Wls	wntless homolog (Drosophila)	0.017
Shc1	src homology 2 domain-containing transforming protein C1	0.017
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.017
Dnm2	dynamin 2	0.016
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.016
Gp5	glycoprotein 5 (platelet)	0.016
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.016
Pdgfb	platelet derived growth factor, B polypeptide	0.016
Prkar1b	protein kinase, cAMP dependent regulatory, type I beta	0.016
Emx1	empty spiracles homolog 1 (Drosophila)	0.016
Dsg4	desmoglein 4	0.015
Arc	activity regulated cytoskeletal-associated protein	0.015
Col12a1	collagen, type XII, alpha 1	0.015
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.015
Gsdma3	gasdermin A3	0.015
Apaf1	apoptotic peptidase activating factor 1	0.015
Otud4	OTU domain containing 4	0.015
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.015
Jak1	Janus kinase 1	0.014
Sulf1	sulfatase 1	0.014	Fly
P2rx7	purinergic receptor P2X, ligand-gated ion channel, 7	0.014
Npy1r	neuropeptide Y receptor Y1	0.014
Stat3	signal transducer and activator of transcription 3	0.014
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.014
Dok2	docking protein 2	0.014
Ankrd17	ankyrin repeat domain 17	0.014
Crebbp	CREB binding protein	0.014
Cybb	cytochrome b-245, beta polypeptide	0.014
Pdpk1	3-phosphoinositide dependent protein kinase 1	0.014
Cd96	CD96 antigen	0.014
Sirpa	signal-regulatory protein alpha	0.013
Flt1	FMS-like tyrosine kinase 1	0.013
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.013
Il1r1	interleukin 1 receptor, type I	0.013
Cd40	CD40 antigen	0.013
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.013
Zbtb7b	zinc finger and BTB domain containing 7B	0.013
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.013
Cdh1	cadherin 1	0.013
Bcl6	B-cell leukemia/lymphoma 6	0.013
Hhat	hedgehog acyltransferase	0.013
Rbl2	retinoblastoma-like 2	0.013
Rora	RAR-related orphan receptor alpha	0.013
H2-Oa	histocompatibility 2, O region alpha locus	0.013
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.012
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.012
Arid1b	AT rich interactive domain 1B (SWI-like)	0.012
Pxn	paxillin	0.012
Cntn1	contactin 1	0.012
Adam17	a disintegrin and metallopeptidase domain 17	0.012	Human
Gab1	growth factor receptor bound protein 2-associated protein 1	0.012
Gna15	guanine nucleotide binding protein, alpha 15	0.012
Rasa1	RAS p21 protein activator 1	0.012
Camk2a	calcium/calmodulin-dependent protein kinase II alpha	0.012
Fzd4	frizzled homolog 4 (Drosophila)	0.012
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.012
Smad4	MAD homolog 4 (Drosophila)	0.012
Sparcl1	SPARC-like 1	0.012
Adam10	a disintegrin and metallopeptidase domain 10	0.012
Camsap1	calmodulin regulated spectrin-associated protein 1	0.012
Sgpl1	sphingosine phosphate lyase 1	0.012
Pdcd6	programmed cell death 6	0.011
Map2k2	mitogen-activated protein kinase kinase 2	0.011
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.011
Rac1	RAS-related C3 botulinum substrate 1	0.011
Atf2	activating transcription factor 2	0.011
Opcml	opioid binding protein/cell adhesion molecule-like	0.011
Plcb1	phospholipase C, beta 1	0.011
Ptk2b	PTK2 protein tyrosine kinase 2 beta	0.011	Fly
Wnt3a	wingless-related MMTV integration site 3A	0.011
Itk	IL2-inducible T-cell kinase	0.011
Sykb	spleen tyrosine kinase	0.011
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.011
Clu	clusterin	0.011
Grm1	glutamate receptor, metabotropic 1	0.011
Nxt1	NTF2-related export protein 1	0.011
Selplg	selectin, platelet (p-selectin) ligand	0.011
Msl1	male-specific lethal 1 homolog (Drosophila)	0.011
Cdt1	chromatin licensing and DNA replication factor 1	0.011
Cd38	CD38 antigen	0.011
Col4a3	collagen, type IV, alpha 3	0.011
Sp1	trans-acting transcription factor 1	0.011
Fzd7	frizzled homolog 7 (Drosophila)	0.011
Il10ra	interleukin 10 receptor, alpha	0.011
Scaf11	SR-related CTD-associated factor 11	0.010
Cpd	carboxypeptidase D	0.010
Vgf	VGF nerve growth factor inducible	0.010
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.010
Qsox1	quiescin Q6 sulfhydryl oxidase 1	0.010
Itm2b	integral membrane protein 2B	0.010
Pde6a	phosphodiesterase 6A, cGMP-specific, rod, alpha	0.010
Tcf7l2	transcription factor 7-like 2, T-cell specific, HMG-box	0.010
Ikzf1	IKAROS family zinc finger 1	0.010
Zfp644	zinc finger protein 644	0.010
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.010
Pkn2	protein kinase N2	0.010
Ldlr	low density lipoprotein receptor	0.010