IMP

Process View

Mus musculus

17 genes annotated in mouse

regulation of protein deacetylation

Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein deacetylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of protein deacetylation" (in gray)

Name	Description	Probability	Func Analog Organism
Trp53	transformation related protein 53	1.000
Jun	Jun oncogene	0.992
Skil	SKI-like	0.990	Mouse
Sin3a	transcriptional regulator, SIN3A (yeast)	0.984
Pten	phosphatase and tensin homolog	0.970
Arid1a	AT rich interactive domain 1A (SWI-like)	0.962
Hdac1	histone deacetylase 1	0.946	Mouse
Vasp	vasodilator-stimulated phosphoprotein	0.835	Mouse
Kat2a	K(lysine) acetyltransferase 2A	0.833
Fos	FBJ osteosarcoma oncogene	0.685	Mouse
Evl	Ena-vasodilator stimulated phosphoprotein	0.580	Mouse
Ncor1	nuclear receptor co-repressor 1	0.503
Plin1	perilipin 1	0.456
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.420
Wfikkn2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.408
Enah	enabled homolog (Drosophila)	0.348	Mouse
Csrp2bp	cysteine and glycine-rich protein 2 binding protein	0.338
Egr1	early growth response 1	0.288
Sox2	SRY-box containing gene 2	0.271
Yy1	YY1 transcription factor	0.257
Srf	serum response factor	0.220
Yeats2	YEATS domain containing 2	0.202
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.190
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.190
Daxx	Fas death domain-associated protein	0.188
Ski	ski sarcoma viral oncogene homolog (avian)	0.168
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.166
Hdac7	histone deacetylase 7	0.158
Zeb1	zinc finger E-box binding homeobox 1	0.151
Tnf	tumor necrosis factor	0.141
Wdr26	WD repeat domain 26	0.134
Igh	immunoglobulin heavy chain complex	0.133
Egr2	early growth response 2	0.126
Rnf44	ring finger protein 44	0.123
Morf4l1	mortality factor 4 like 1	0.119
Mdm2	transformed mouse 3T3 cell double minute 2	0.108
Plaur	plasminogen activator, urokinase receptor	0.105
Atf3	activating transcription factor 3	0.103	Mouse
Arid2	AT rich interactive domain 2 (ARID, RFX-like)	0.101
Yap1	yes-associated protein 1	0.098
Ednra	endothelin receptor type A	0.097
5430411K18Rik	RIKEN cDNA 5430411K18 gene	0.094
Hr	hairless	0.094
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.094
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.093
Plxnd1	plexin D1	0.091
Pml	promyelocytic leukemia	0.088	Human
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.084
Mta2	metastasis-associated gene family, member 2	0.084
Casp8	caspase 8	0.083
Ncoa1	nuclear receptor coactivator 1	0.082
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.080
Zfp362	zinc finger protein 362	0.080
Trp73	transformation related protein 73	0.078	Mouse
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.069
Smad7	MAD homolog 7 (Drosophila)	0.069
Cxcl2	chemokine (C-X-C motif) ligand 2	0.067
Mdm4	transformed mouse 3T3 cell double minute 4	0.067
Rhob	ras homolog gene family, member B	0.062
Adamts1	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1	0.061
Zfp36	zinc finger protein 36	0.061
Trrap	transformation/transcription domain-associated protein	0.060
Rc3h1	RING CCCH (C3H) domains 1	0.058
Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	0.058
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.058
Cyr61	cysteine rich protein 61	0.058
Rara	retinoic acid receptor, alpha	0.056
Sfn	stratifin	0.055
Sp1	trans-acting transcription factor 1	0.054
Tgfbr1	transforming growth factor, beta receptor I	0.052
Fbxw7	F-box and WD-40 domain protein 7	0.051
Notch1	Notch gene homolog 1 (Drosophila)	0.051
Runx1	runt related transcription factor 1	0.051
Fosb	FBJ osteosarcoma oncogene B	0.050	Mouse
Tada3	transcriptional adaptor 3	0.049
Actn1	actinin, alpha 1	0.048
Klf4	Kruppel-like factor 4 (gut)	0.048
Ptgs2	prostaglandin-endoperoxide synthase 2	0.047
Nfil3	nuclear factor, interleukin 3, regulated	0.047
Stat3	signal transducer and activator of transcription 3	0.045
Fadd	Fas (TNFRSF6)-associated via death domain	0.045
Mll5	myeloid/lymphoid or mixed-lineage leukemia 5	0.045
Nab2	Ngfi-A binding protein 2	0.044
Klf6	Kruppel-like factor 6	0.044
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.043
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.043
Ghr	growth hormone receptor	0.040
Dusp1	dual specificity phosphatase 1	0.039
Zyx	zyxin	0.039
Rcor1	REST corepressor 1	0.038
Elof1	elongation factor 1 homolog (ELF1, S. cerevisiae)	0.037
Pygo2	pygopus 2	0.035
Basp1	brain abundant, membrane attached signal protein 1	0.034
Nanog	Nanog homeobox	0.034
Kdm2b	lysine (K)-specific demethylase 2B	0.034
Tbl1x	transducin (beta)-like 1 X-linked	0.034	Fly
Ncdn	neurochondrin	0.033
Mecp2	methyl CpG binding protein 2	0.032
Grk6	G protein-coupled receptor kinase 6	0.032
Sntb2	syntrophin, basic 2	0.032
Dmd	dystrophin, muscular dystrophy	0.031
Spry4	sprouty homolog 4 (Drosophila)	0.031
Hbegf	heparin-binding EGF-like growth factor	0.030
Elavl1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.030
Klf7	Kruppel-like factor 7 (ubiquitous)	0.029
Hcfc1	host cell factor C1	0.028
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.028
Cxcl1	chemokine (C-X-C motif) ligand 1	0.028
Gtf2ird1	general transcription factor II I repeat domain-containing 1	0.027
Ppl	periplakin	0.027
Traf2	TNF receptor-associated factor 2	0.027
Hivep1	human immunodeficiency virus type I enhancer binding protein 1	0.026
Traf6	TNF receptor-associated factor 6	0.026
Fst	follistatin	0.026
Tada2a	transcriptional adaptor 2A	0.025
Nr4a2	nuclear receptor subfamily 4, group A, member 2	0.024
Thra	thyroid hormone receptor alpha	0.024
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform	0.024
Dag1	dystroglycan 1	0.024
Junb	Jun-B oncogene	0.024
Vcl	vinculin	0.024
Rcan1	regulator of calcineurin 1	0.024
Sept9	septin 9	0.023
Btg2	B-cell translocation gene 2, anti-proliferative	0.023
Apbb1ip	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein	0.023
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.023
Ptf1a	pancreas specific transcription factor, 1a	0.023
Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.022
Gem	GTP binding protein (gene overexpressed in skeletal muscle)	0.022
Gna13	guanine nucleotide binding protein, alpha 13	0.022
Kitl	kit ligand	0.022
Trim8	tripartite motif-containing 8	0.021
Lamc2	laminin, gamma 2	0.021
Wiz	widely-interspaced zinc finger motifs	0.021
Zswim6	zinc finger, SWIM domain containing 6	0.021
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.021
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.021
Trip12	thyroid hormone receptor interactor 12	0.021
Mtap1s	microtubule-associated protein 1S	0.021
Irf6	interferon regulatory factor 6	0.020
Kdm5b	lysine (K)-specific demethylase 5B	0.020	Mouse
Stat6	signal transducer and activator of transcription 6	0.020
Mex3c	mex3 homolog C (C. elegans)	0.020
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.020
Lep	leptin	0.020
Mstn	myostatin	0.020	Mouse
Acvr1	activin A receptor, type 1	0.020
Chd4	chromodomain helicase DNA binding protein 4	0.019
Uty	ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome	0.019
Pum1	pumilio 1 (Drosophila)	0.019
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.019
Men1	multiple endocrine neoplasia 1	0.019
Ctbp2	C-terminal binding protein 2	0.019
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.019
Pdgfa	platelet derived growth factor, alpha	0.019
Frmd6	FERM domain containing 6	0.019
Siah2	seven in absentia 2	0.019
Ppard	peroxisome proliferator activator receptor delta	0.018
Jarid2	jumonji, AT rich interactive domain 2	0.018
Arl4c	ADP-ribosylation factor-like 4C	0.018
Csk	c-src tyrosine kinase	0.018
Fosl2	fos-like antigen 2	0.018	Mouse
Mitf	microphthalmia-associated transcription factor	0.018
Batf	basic leucine zipper transcription factor, ATF-like	0.018
Ahr	aryl-hydrocarbon receptor	0.018
Wwtr1	WW domain containing transcription regulator 1	0.017
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.017
Fyn	Fyn proto-oncogene	0.017
Hip1	huntingtin interacting protein 1	0.017
Gatad2a	GATA zinc finger domain containing 2A	0.017
Polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.017
Egln1	EGL nine homolog 1 (C. elegans)	0.016
Marcksl1	MARCKS-like 1	0.016
Rest	RE1-silencing transcription factor	0.016
Crebbp	CREB binding protein	0.016
Tead1	TEA domain family member 1	0.016
Cul9	cullin 9	0.016
Ccnd1	cyclin D1	0.016
Ifng	interferon gamma	0.016
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.016
Trp63	transformation related protein 63	0.016	Mouse
Cic	capicua homolog (Drosophila)	0.016
Foxc2	forkhead box C2	0.015
Mta1	metastasis associated 1	0.015
Socs1	suppressor of cytokine signaling 1	0.015
Midn	midnolin	0.015
Huwe1	HECT, UBA and WWE domain containing 1	0.015
Klc1	kinesin light chain 1	0.015
Itch	itchy, E3 ubiquitin protein ligase	0.015
Etv6	ets variant gene 6 (TEL oncogene)	0.015
Tead3	TEA domain family member 3	0.015
Socs5	suppressor of cytokine signaling 5	0.015
Mapk8	mitogen-activated protein kinase 8	0.015	Human
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2	0.015
Efna5	ephrin A5	0.014
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.014
Cxcl10	chemokine (C-X-C motif) ligand 10	0.014
Csnk1e	casein kinase 1, epsilon	0.014
Ylpm1	YLP motif containing 1	0.014
Tcf4	transcription factor 4	0.014
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.014
Rel	reticuloendotheliosis oncogene	0.014
E2f1	E2F transcription factor 1	0.014
Akt3	thymoma viral proto-oncogene 3	0.013
Il10	interleukin 10	0.013
Sdc4	syndecan 4	0.013
Zfp36l1	zinc finger protein 36, C3H type-like 1	0.013
Foxo1	forkhead box O1	0.013
Kdr	kinase insert domain protein receptor	0.013
Trim55	tripartite motif-containing 55	0.013
Taok1	TAO kinase 1	0.013
Pik3c2a	phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide	0.013
Wwox	WW domain-containing oxidoreductase	0.013
Tsc22d2	TSC22 domain family, member 2	0.013
Tgif1	TGFB-induced factor homeobox 1	0.013
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.013
Map3k1	mitogen-activated protein kinase kinase kinase 1	0.013
Tiparp	TCDD-inducible poly(ADP-ribose) polymerase	0.013
Stat5a	signal transducer and activator of transcription 5A	0.012
Irf2bp2	interferon regulatory factor 2 binding protein 2	0.012
Ccnd2	cyclin D2	0.012
Qrich1	glutamine-rich 1	0.012
Ncor2	nuclear receptor co-repressor 2	0.012	Mouse
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.012
Rhog	ras homolog gene family, member G	0.012
LOC100503441	hypothetical protein LOC100503441	0.012
Cxcr4	chemokine (C-X-C motif) receptor 4	0.012
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.012	Mouse
Wisp1	WNT1 inducible signaling pathway protein 1	0.012
Mapk7	mitogen-activated protein kinase 7	0.012
Has2	hyaluronan synthase 2	0.012
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.012
Gm10244	predicted gene 10244	0.012
Mea1	male enhanced antigen 1	0.012
Scd2	stearoyl-Coenzyme A desaturase 2	0.012
Mef2d	myocyte enhancer factor 2D	0.012
Dusp16	dual specificity phosphatase 16	0.012
Hs2st1	heparan sulfate 2-O-sulfotransferase 1	0.012
Etv5	ets variant gene 5	0.012
Phf12	PHD finger protein 12	0.012
Plekho2	pleckstrin homology domain containing, family O member 2	0.011
Mapk14	mitogen-activated protein kinase 14	0.011
Rad54l2	RAD54 like 2 (S. cerevisiae)	0.011
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.011
Zc3h12c	zinc finger CCCH type containing 12C	0.011
Snrk	SNF related kinase	0.011
Tet1	tet oncogene 1	0.011
Inhba	inhibin beta-A	0.011
Nfib	nuclear factor I/B	0.011
Tgif2	TGFB-induced factor homeobox 2	0.011
Pvr	poliovirus receptor	0.011
Irf1	interferon regulatory factor 1	0.011
Cd40	CD40 antigen	0.011
Nes	nestin	0.011
Myo10	myosin X	0.011
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.011
Zbtb7a	zinc finger and BTB domain containing 7a	0.011
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.011
Mll3	myeloid/lymphoid or mixed-lineage leukemia 3	0.011
Ythdf1	YTH domain family 1	0.011
Dhcr7	7-dehydrocholesterol reductase	0.011
Trak1	trafficking protein, kinesin binding 1	0.010
Cnot2	CCR4-NOT transcription complex, subunit 2	0.010
Elk4	ELK4, member of ETS oncogene family	0.010
A230046K03Rik	RIKEN cDNA A230046K03 gene	0.010
Dok1	docking protein 1	0.010
Zmym5	zinc finger, MYM-type 5	0.010
Med14	mediator complex subunit 14	0.010
Hdac2	histone deacetylase 2	0.010
Ripk3	receptor-interacting serine-threonine kinase 3	0.010
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.010
Prr12	proline rich 12	0.010
Lasp1	LIM and SH3 protein 1	0.010
Abhd5	abhydrolase domain containing 5	0.010
Otx1	orthodenticle homolog 1 (Drosophila)	0.010
Agrp	agouti related protein	0.010
Atm	ataxia telangiectasia mutated homolog (human)	0.010
Tead4	TEA domain family member 4	0.010
Sh2b3	SH2B adaptor protein 3	0.010
Axin1	axin 1	0.010
Fzd4	frizzled homolog 4 (Drosophila)	0.010