IMP

Process View

Mus musculus

4 genes annotated in mouse

Multi-species View

regulation of t cell anergy

GO:0002667

Any process that modulates the frequency, rate, or extent of T cell anergy.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t cell anergy"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t cell anergy" (in gray)

Name	Description	Probability	Func Analog Organism
Lat	linker for activation of T cells	0.944
Cd19	CD19 antigen	0.910
Lck	lymphocyte protein tyrosine kinase	0.823
Zap70	zeta-chain (TCR) associated protein kinase	0.744
Tcra	T-cell receptor alpha chain	0.691
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.659
Cyld	cylindromatosis (turban tumor syndrome)	0.653
Fyn	Fyn proto-oncogene	0.609
Trp53	transformation related protein 53	0.493
Cd28	CD28 antigen	0.444
Stat3	signal transducer and activator of transcription 3	0.426
Cd3g	CD3 antigen, gamma polypeptide	0.422	Mouse
Foxp1	forkhead box P1	0.411	Mouse
Cd6	CD6 antigen	0.356
Traf6	TNF receptor-associated factor 6	0.354
Itk	IL2-inducible T-cell kinase	0.354
Cd247	CD247 antigen	0.350
Rac1	RAS-related C3 botulinum substrate 1	0.316
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.298
Cd27	CD27 antigen	0.279
Cd8a	CD8 antigen, alpha chain	0.267
Rnf11	ring finger protein 11	0.256
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.234
Cd8b1	CD8 antigen, beta chain 1	0.226
Gli2	GLI-Kruppel family member GLI2	0.218
Smad6	MAD homolog 6 (Drosophila)	0.206
Apc	adenomatosis polyposis coli	0.203
Cd2	CD2 antigen	0.203
Ikzf1	IKAROS family zinc finger 1	0.201
Il6st	interleukin 6 signal transducer	0.187
Pmepa1	prostate transmembrane protein, androgen induced 1	0.129
Abl1	c-abl oncogene 1, non-receptor tyrosine kinase	0.126
Smad7	MAD homolog 7 (Drosophila)	0.123
Ctsw	cathepsin W	0.109
Tax1bp1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.108
Il27ra	interleukin 27 receptor, alpha	0.104
Il4	interleukin 4	0.102
Tmem64	transmembrane protein 64	0.100
Ticam1	toll-like receptor adaptor molecule 1	0.094
Itsn1	intersectin 1 (SH3 domain protein 1A)	0.089
Stat6	signal transducer and activator of transcription 6	0.085
Pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.083
Grb10	growth factor receptor bound protein 10	0.083
Cd3d	CD3 antigen, delta polypeptide	0.083	Mouse
Stat5b	signal transducer and activator of transcription 5B	0.082
Sept1	septin 1	0.079
Shc1	src homology 2 domain-containing transforming protein C1	0.078
Kit	kit oncogene	0.076
Dvl2	dishevelled 2, dsh homolog (Drosophila)	0.076
Cd96	CD96 antigen	0.074
Rag1	recombination activating gene 1	0.072
Smad4	MAD homolog 4 (Drosophila)	0.071
Cd4	CD4 antigen	0.070
Foxn1	forkhead box N1	0.070
Sh2d1a	SH2 domain protein 1A	0.068
Sit1	suppression inducing transmembrane adaptor 1	0.066
Sh2d2a	SH2 domain protein 2A	0.065
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.063
Socs1	suppressor of cytokine signaling 1	0.061
Cldn3	claudin 3	0.060
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.058
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.054
Tbl1x	transducin (beta)-like 1 X-linked	0.054
Smad1	MAD homolog 1 (Drosophila)	0.052
Gnaq	guanine nucleotide binding protein, alpha q polypeptide	0.052
Fas	Fas (TNF receptor superfamily member 6)	0.052
Nkd2	naked cuticle 2 homolog (Drosophila)	0.052
Cd7	CD7 antigen	0.051
Cflar	CASP8 and FADD-like apoptosis regulator	0.051
Card11	caspase recruitment domain family, member 11	0.050
Prkcq	protein kinase C, theta	0.049
Ubc	ubiquitin C	0.049
Foxp2	forkhead box P2	0.049	Mouse
Txk	TXK tyrosine kinase	0.048
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.048
Il2rb	interleukin 2 receptor, beta chain	0.047
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.046
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.044
Gimap3	GTPase, IMAP family member 3	0.044
Meox2	mesenchyme homeobox 2	0.042
Rhoh	ras homolog gene family, member H	0.042
Crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.042
Gimap7	GTPase, IMAP family member 7	0.041
Prdx6	peroxiredoxin 6	0.040
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.038
Itgb7	integrin beta 7	0.038
Trp53bp1	transformation related protein 53 binding protein 1	0.038
Cxcr3	chemokine (C-X-C motif) receptor 3	0.038
Smurf1	SMAD specific E3 ubiquitin protein ligase 1	0.037	Mouse
Il2	interleukin 2	0.034
Notch1	Notch gene homolog 1 (Drosophila)	0.034
Il2rg	interleukin 2 receptor, gamma chain	0.034
Gzma	granzyme A	0.033
Tspan32	tetraspanin 32	0.033
Tmem79	transmembrane protein 79	0.031
Ralbp1	ralA binding protein 1	0.031
Ifng	interferon gamma	0.031
Phf2	PHD finger protein 2	0.030
Igf1r	insulin-like growth factor I receptor	0.030
Sorbs1	sorbin and SH3 domain containing 1	0.030
Arid1b	AT rich interactive domain 1B (SWI-like)	0.029
Scnn1a	sodium channel, nonvoltage-gated 1 alpha	0.029
Folr4	folate receptor 4 (delta)	0.029
Ly6d	lymphocyte antigen 6 complex, locus D	0.029
Fign	fidgetin	0.029
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.029
Myd88	myeloid differentiation primary response gene 88	0.029
Stat5a	signal transducer and activator of transcription 5A	0.028
Pkp3	plakophilin 3	0.028
BC021614	cDNA sequence BC021614	0.027
Git2	G protein-coupled receptor kinase-interactor 2	0.027
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.027
Wbp1	WW domain binding protein 1	0.027
Stim1	stromal interaction molecule 1	0.026
Cxcr6	chemokine (C-X-C motif) receptor 6	0.026
Arhgef16	Rho guanine nucleotide exchange factor (GEF) 16	0.026
Map3k2	mitogen-activated protein kinase kinase kinase 2	0.026
Bcl11b	B-cell leukemia/lymphoma 11B	0.025
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.025
Pglyrp2	peptidoglycan recognition protein 2	0.025
Bach2	BTB and CNC homology 2	0.024
Smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.024	Mouse
Cblb	Casitas B-lineage lymphoma b	0.024
Vav1	vav 1 oncogene	0.024
Gtf2i	general transcription factor II I	0.024
Cd5	CD5 antigen	0.023
Fam160b1	family with sequence similarity 160, member B1	0.023
Prrg2	proline-rich Gla (G-carboxyglutamic acid) polypeptide 2	0.023
Ccr7	chemokine (C-C motif) receptor 7	0.022
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.022
Fmnl1	formin-like 1	0.022
Oxr1	oxidation resistance 1	0.022
Vangl2	vang-like 2 (van gogh, Drosophila)	0.022
Zfp362	zinc finger protein 362	0.022
Pknox1	Pbx/knotted 1 homeobox	0.021
Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	0.021
Axin1	axin 1	0.021
Ikzf3	IKAROS family zinc finger 3	0.021
Nfil3	nuclear factor, interleukin 3, regulated	0.020
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.020
Cd2ap	CD2-associated protein	0.020
Ptprc	protein tyrosine phosphatase, receptor type, C	0.020
Ahr	aryl-hydrocarbon receptor	0.020
Skil	SKI-like	0.019
Usp8	ubiquitin specific peptidase 8	0.019
Sla2	Src-like-adaptor 2	0.019
Cdk6	cyclin-dependent kinase 6	0.018
Atp6v1c2	ATPase, H+ transporting, lysosomal V1 subunit C2	0.018
Sh2b2	SH2B adaptor protein 2	0.018
Ctnnb1	catenin (cadherin associated protein), beta 1	0.018
Bbx	bobby sox homolog (Drosophila)	0.018
Flt1	FMS-like tyrosine kinase 1	0.018
Rpl27a	ribosomal protein L27A	0.018
Nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.018
Cbl	Casitas B-lineage lymphoma	0.018	Mouse
Sh3kbp1	SH3-domain kinase binding protein 1	0.017
Gab1	growth factor receptor bound protein 2-associated protein 1	0.017
Kitl	kit ligand	0.017
Hhex	hematopoietically expressed homeobox	0.017
Egfr	epidermal growth factor receptor	0.017
Lpp	LIM domain containing preferred translocation partner in lipoma	0.017
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.017
Hdlbp	high density lipoprotein (HDL) binding protein	0.017
Tbc1d22b	TBC1 domain family, member 22B	0.017
Hcst	hematopoietic cell signal transducer	0.016
S1pr4	sphingosine-1-phosphate receptor 4	0.016
Tbc1d10c	TBC1 domain family, member 10c	0.016
Tbc1d4	TBC1 domain family, member 4	0.016
Epha1	Eph receptor A1	0.016
Ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.016
Ctdsp2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.016
Skap1	src family associated phosphoprotein 1	0.016
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.016
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.016
Klf7	Kruppel-like factor 7 (ubiquitous)	0.016
4921513D23Rik	RIKEN cDNA 4921513D23 gene	0.015
Arrdc1	arrestin domain containing 1	0.015
Sipa1l1	signal-induced proliferation-associated 1 like 1	0.015
Eps8l1	EPS8-like 1	0.015
Plekhg6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.015
Slamf6	SLAM family member 6	0.015
Gata3	GATA binding protein 3	0.015
Aplp2	amyloid beta (A4) precursor-like protein 2	0.015
Wfdc2	WAP four-disulfide core domain 2	0.014
Il17rb	interleukin 17 receptor B	0.014
Stard13	StAR-related lipid transfer (START) domain containing 13	0.014
Cpd	carboxypeptidase D	0.014
Jak2	Janus kinase 2	0.014
Lad1	ladinin	0.014
Klk8	kallikrein related-peptidase 8	0.014
Pard6a	par-6 (partitioning defective 6,) homolog alpha (C. elegans)	0.014
Mll1	myeloid/lymphoid or mixed-lineage leukemia 1	0.014
Btbd7	BTB (POZ) domain containing 7	0.014
Vangl1	vang-like 1 (van gogh, Drosophila)	0.014
Fam168a	family with sequence similarity 168, member A	0.014
Ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.014
Add1	adducin 1 (alpha)	0.013
Jak1	Janus kinase 1	0.013
Pak1	p21 protein (Cdc42/Rac)-activated kinase 1	0.013
Fmo2	flavin containing monooxygenase 2	0.013
Smad5	MAD homolog 5 (Drosophila)	0.013
Itgae	integrin alpha E, epithelial-associated	0.013
Xrn1	5'-3' exoribonuclease 1	0.013
Hook3	hook homolog 3 (Drosophila)	0.013
Atp11c	ATPase, class VI, type 11C	0.013
Sytl1	synaptotagmin-like 1	0.013
Rara	retinoic acid receptor, alpha	0.013
St14	suppression of tumorigenicity 14 (colon carcinoma)	0.013
Dgcr2	DiGeorge syndrome critical region gene 2	0.013
Eif4b	eukaryotic translation initiation factor 4B	0.013
Agl	amylo-1,6-glucosidase, 4-alpha-glucanotransferase	0.013
Traf3ip3	TRAF3 interacting protein 3	0.012
Ccl22	chemokine (C-C motif) ligand 22	0.012
H2-Oa	histocompatibility 2, O region alpha locus	0.012
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.012
Snx20	sorting nexin 20	0.012
Tbx21	T-box 21	0.012
Mall	mal, T-cell differentiation protein-like	0.012
Whsc1l1	Wolf-Hirschhorn syndrome candidate 1-like 1 (human)	0.012
Pstpip2	proline-serine-threonine phosphatase-interacting protein 2	0.012
Prkce	protein kinase C, epsilon	0.012
Chd4	chromodomain helicase DNA binding protein 4	0.012
Dnase1l3	deoxyribonuclease 1-like 3	0.012
Tet2	tet oncogene family member 2	0.012
Phf21a	PHD finger protein 21A	0.012
Med15	mediator complex subunit 15	0.012
Zcchc14	zinc finger, CCHC domain containing 14	0.012
Mpp5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)	0.012
Ap1m2	adaptor protein complex AP-1, mu 2 subunit	0.012
Elmo3	engulfment and cell motility 3, ced-12 homolog (C. elegans)	0.012
Dlg3	discs, large homolog 3 (Drosophila)	0.012
Arhgef26	Rho guanine nucleotide exchange factor (GEF) 26	0.012
Rasal3	RAS protein activator like 3	0.011
Pten	phosphatase and tensin homolog	0.011
Krtcap3	keratinocyte associated protein 3	0.011
Cd79b	CD79B antigen	0.011
L3mbtl3	l(3)mbt-like 3 (Drosophila)	0.011
Ptch1	patched homolog 1	0.011
Dag1	dystroglycan 1	0.011
Lax1	lymphocyte transmembrane adaptor 1	0.011
Stat4	signal transducer and activator of transcription 4	0.011
Smc1a	structural maintenance of chromosomes 1A	0.011
Ssh2	slingshot homolog 2 (Drosophila)	0.011
Arhgap9	Rho GTPase activating protein 9	0.011
Mbtps1	membrane-bound transcription factor peptidase, site 1	0.011
Rnf111	ring finger 111	0.011
Phkb	phosphorylase kinase beta	0.011
Nedd4	neural precursor cell expressed, developmentally down-regulated 4	0.011	Mouse
Cxcr5	chemokine (C-X-C motif) receptor 5	0.011
Cald1	caldesmon 1	0.011
Spint1	serine protease inhibitor, Kunitz type 1	0.011
Rnf186	ring finger protein 186	0.011
Ep300	E1A binding protein p300	0.011
Robo2	roundabout homolog 2 (Drosophila)	0.011
Acly	ATP citrate lyase	0.011
Malt1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.010
5830427D02Rik	RIKEN cDNA 5830427D02 gene	0.010
Gatad2b	GATA zinc finger domain containing 2B	0.010
Pla2g2d	phospholipase A2, group IID	0.010
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.010
Trp53bp2	transformation related protein 53 binding protein 2	0.010
Add3	adducin 3 (gamma)	0.010
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.010
Scnn1b	sodium channel, nonvoltage-gated 1 beta	0.010
Huwe1	HECT, UBA and WWE domain containing 1	0.010
Pdcd6ip	programmed cell death 6 interacting protein	0.010
Zfhx3	zinc finger homeobox 3	0.010
Vnn3	vanin 3	0.010
Marveld3	MARVEL (membrane-associating) domain containing 3	0.010
H2-Q8	histocompatibility 2, Q region locus 8	0.010
Batf	basic leucine zipper transcription factor, ATF-like	0.010
Stxbp2	syntaxin binding protein 2	0.010
Hhip	Hedgehog-interacting protein	0.010
Ets1	E26 avian leukemia oncogene 1, 5' domain	0.010
Plce1	phospholipase C, epsilon 1	0.010