IMP

Process View

Mus musculus

7 genes annotated in mouse

Multi-species View

regulation of t helper 1 cell differentiation

GO:0045625

Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of t helper 1 cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of t helper 1 cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
Socs1	suppressor of cytokine signaling 1	0.998	Mouse
Csf2rb2	colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)	0.997	Mouse
Tnf	tumor necrosis factor	0.994
Jak2	Janus kinase 2	0.991	Mouse
Ccl2	chemokine (C-C motif) ligand 2	0.982
Stat3	signal transducer and activator of transcription 3	0.975
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.954
Socs3	suppressor of cytokine signaling 3	0.928	Mouse
Lepr	leptin receptor	0.923
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.893
Fas	Fas (TNF receptor superfamily member 6)	0.875
Csf2rb	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.773	Mouse
Batf	basic leucine zipper transcription factor, ATF-like	0.770
Ccl12	chemokine (C-C motif) ligand 12	0.720	Mouse
Ifng	interferon gamma	0.656
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.574
Ccr1	chemokine (C-C motif) receptor 1	0.566
Foxp3	forkhead box P3	0.555
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105	0.504
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.481
Ch25h	cholesterol 25-hydroxylase	0.477
Il1b	interleukin 1 beta	0.380
Il6	interleukin 6	0.370
Cxcl2	chemokine (C-X-C motif) ligand 2	0.355
Lyz2	lysozyme 2	0.348
Ccr2	chemokine (C-C motif) receptor 2	0.328
Stat5a	signal transducer and activator of transcription 5A	0.322
Bcl3	B-cell leukemia/lymphoma 3	0.311
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.304
Ccl8	chemokine (C-C motif) ligand 8	0.267
Cish	cytokine inducible SH2-containing protein	0.258	Mouse
Il6st	interleukin 6 signal transducer	0.248
Ccl3	chemokine (C-C motif) ligand 3	0.247	Mouse
Foxn1	forkhead box N1	0.236
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.231
Ccl7	chemokine (C-C motif) ligand 7	0.210	Mouse
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.206
Cxcl9	chemokine (C-X-C motif) ligand 9	0.191
Cd44	CD44 antigen	0.182
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.170
C3ar1	complement component 3a receptor 1	0.170
Pim1	proviral integration site 1	0.154
Msr1	macrophage scavenger receptor 1	0.145
Il1rn	interleukin 1 receptor antagonist	0.143
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.141
Icam1	intercellular adhesion molecule 1	0.140
Cd86	CD86 antigen	0.127
Irg1	immunoresponsive gene 1	0.123
Il2rg	interleukin 2 receptor, gamma chain	0.116
Cxcl1	chemokine (C-X-C motif) ligand 1	0.112
Saa3	serum amyloid A 3	0.112
Tnfrsf9	tumor necrosis factor receptor superfamily, member 9	0.107
Mmp12	matrix metallopeptidase 12	0.096
Cd40	CD40 antigen	0.093
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.093
Irf5	interferon regulatory factor 5	0.093
Serpina3g	serine (or cysteine) peptidase inhibitor, clade A, member 3G	0.093
Mx2	myxovirus (influenza virus) resistance 2	0.087
Ubd	ubiquitin D	0.086
Il3ra	interleukin 3 receptor, alpha chain	0.083
Ccl4	chemokine (C-C motif) ligand 4	0.082	Mouse
Map3k14	mitogen-activated protein kinase kinase kinase 14	0.082
Batf2	basic leucine zipper transcription factor, ATF-like 2	0.082
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.081
Lag3	lymphocyte-activation gene 3	0.080
Stat5b	signal transducer and activator of transcription 5B	0.080
Serpina3n	serine (or cysteine) peptidase inhibitor, clade A, member 3N	0.075
Ccl22	chemokine (C-C motif) ligand 22	0.075
Tgfb1	transforming growth factor, beta 1	0.069
Irf1	interferon regulatory factor 1	0.068
Stat6	signal transducer and activator of transcription 6	0.067
Selp	selectin, platelet	0.067
Pdcd1	programmed cell death 1	0.063
Gdf15	growth differentiation factor 15	0.061
Fcgr1	Fc receptor, IgG, high affinity I	0.058
Il10ra	interleukin 10 receptor, alpha	0.057
Gzma	granzyme A	0.056
Csf1	colony stimulating factor 1 (macrophage)	0.055
Ccr5	chemokine (C-C motif) receptor 5	0.054
Cxcl10	chemokine (C-X-C motif) ligand 10	0.054
Tnip1	TNFAIP3 interacting protein 1	0.052
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.051
Socs2	suppressor of cytokine signaling 2	0.049	Mouse
Casp8	caspase 8	0.048
Il10	interleukin 10	0.047
Il2rb	interleukin 2 receptor, beta chain	0.046
Ptprc	protein tyrosine phosphatase, receptor type, C	0.039
Arid5a	AT rich interactive domain 5A (MRF1-like)	0.036
St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	0.035
Il1r2	interleukin 1 receptor, type II	0.035
Aire	autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)	0.034
Cul5	cullin 5	0.034
Clec4d	C-type lectin domain family 4, member d	0.034
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.033
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.032
Traf6	TNF receptor-associated factor 6	0.032
Folr2	folate receptor 2 (fetal)	0.030
Egr2	early growth response 2	0.030
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.028
Jak3	Janus kinase 3	0.028
Il12rb1	interleukin 12 receptor, beta 1	0.028
Sh2b1	SH2B adaptor protein 1	0.028
Itgax	integrin alpha X	0.027
Plekho2	pleckstrin homology domain containing, family O member 2	0.026
Il4ra	interleukin 4 receptor, alpha	0.026
Ifngr2	interferon gamma receptor 2	0.025
Plaur	plasminogen activator, urokinase receptor	0.024
Ikzf1	IKAROS family zinc finger 1	0.024
Rel	reticuloendotheliosis oncogene	0.024
Tbxas1	thromboxane A synthase 1, platelet	0.024
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.024
Il1r1	interleukin 1 receptor, type I	0.023
Clec4n	C-type lectin domain family 4, member n	0.022
Egfr	epidermal growth factor receptor	0.021
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.021
Nlrp3	NLR family, pyrin domain containing 3	0.021
Ccl6	chemokine (C-C motif) ligand 6	0.020	Mouse
C3	complement component 3	0.020
Junb	Jun-B oncogene	0.020
Xcl1	chemokine (C motif) ligand 1	0.019	Mouse
Gzmc	granzyme C	0.019
Slpi	secretory leukocyte peptidase inhibitor	0.018
Cd14	CD14 antigen	0.018
Ugcg	UDP-glucose ceramide glucosyltransferase	0.018
Mmp3	matrix metallopeptidase 3	0.018
Ccl17	chemokine (C-C motif) ligand 17	0.018	Mouse
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.017
Lta	lymphotoxin A	0.017
Dusp2	dual specificity phosphatase 2	0.017
Clec4e	C-type lectin domain family 4, member e	0.017
Fadd	Fas (TNFRSF6)-associated via death domain	0.017
Sh2d2a	SH2 domain protein 2A	0.017
Rgs16	regulator of G-protein signaling 16	0.017
Atf3	activating transcription factor 3	0.016
Slamf8	SLAM family member 8	0.016
Pdcd1lg2	programmed cell death 1 ligand 2	0.016
Creb1	cAMP responsive element binding protein 1	0.016
Cd7	CD7 antigen	0.015
Ctsw	cathepsin W	0.015
Il17ra	interleukin 17 receptor A	0.015
Pitx3	paired-like homeodomain transcription factor 3	0.015
Ccr7	chemokine (C-C motif) receptor 7	0.015
F10	coagulation factor X	0.014
Rgs1	regulator of G-protein signaling 1	0.014
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.014
Ctla4	cytotoxic T-lymphocyte-associated protein 4	0.014
Cd80	CD80 antigen	0.014
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.014
Slc15a3	solute carrier family 15, member 3	0.014
Traf1	TNF receptor-associated factor 1	0.013
Gpr35	G protein-coupled receptor 35	0.013
Gm11428	predicted gene 11428	0.013
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.013
4933426M11Rik	RIKEN cDNA 4933426M11 gene	0.013
Tnfsf9	tumor necrosis factor (ligand) superfamily, member 9	0.013
Has1	hyaluronan synthase1	0.013
Timp1	tissue inhibitor of metalloproteinase 1	0.013
Lgals7	lectin, galactose binding, soluble 7	0.013
Adam8	a disintegrin and metallopeptidase domain 8	0.013
Nfkbiz	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.013
Ccl9	chemokine (C-C motif) ligand 9	0.012	Mouse
Snx20	sorting nexin 20	0.012
Tnfrsf18	tumor necrosis factor receptor superfamily, member 18	0.012
Tmem173	transmembrane protein 173	0.012
Hhex	hematopoietically expressed homeobox	0.012
C5ar1	complement component 5a receptor 1	0.012
Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	0.012
Ptgir	prostaglandin I receptor (IP)	0.011
Myd88	myeloid differentiation primary response gene 88	0.011
Birc3	baculoviral IAP repeat-containing 3	0.011
Gab2	growth factor receptor bound protein 2-associated protein 2	0.011
Vdr	vitamin D receptor	0.011
Tcra	T-cell receptor alpha chain	0.011
Spred1	sprouty protein with EVH-1 domain 1, related sequence	0.010
Cxcl16	chemokine (C-X-C motif) ligand 16	0.010
Sfn	stratifin	0.010
Mxd1	MAX dimerization protein 1	0.010
Il1a	interleukin 1 alpha	0.010