IMP

Process View

Mus musculus

13 genes annotated in mouse

somite rostral caudal axis specification

The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "somite rostral caudal axis specification"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "somite rostral caudal axis specification" (in gray)

Name	Description	Probability	Func Analog Organism
Pitx2	paired-like homeodomain transcription factor 2	1.000
Shh	sonic hedgehog	1.000
Otx2	orthodenticle homolog 2 (Drosophila)	0.999
Foxc1	forkhead box C1	0.999	Mouse
Pax2	paired box gene 2	0.999
Tbx1	T-box 1	0.996	Mouse
Fgf8	fibroblast growth factor 8	0.994
Nodal	nodal	0.993
Fgfr2	fibroblast growth factor receptor 2	0.990
Gli3	GLI-Kruppel family member GLI3	0.987
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.980
Pax3	paired box gene 3	0.972
Hoxa1	homeobox A1	0.971
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.959
Bmp4	bone morphogenetic protein 4	0.952	Mouse
Foxc2	forkhead box C2	0.945	Mouse
Gata4	GATA binding protein 4	0.929
Hand1	heart and neural crest derivatives expressed transcript 1	0.926
Foxg1	forkhead box G1	0.921	Mouse
Tcfap2a	transcription factor AP-2, alpha	0.900
Hand2	heart and neural crest derivatives expressed transcript 2	0.893
Zic3	zinc finger protein of the cerebellum 3	0.878
Eya1	eyes absent 1 homolog (Drosophila)	0.877
Chd7	chromodomain helicase DNA binding protein 7	0.855
Prrx1	paired related homeobox 1	0.852
Tbx3	T-box 3	0.845	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.838	Mouse
Pitx1	paired-like homeodomain transcription factor 1	0.798
Foxh1	forkhead box H1	0.776	Zebrafish
Nog	noggin	0.761
Ctnnb1	catenin (cadherin associated protein), beta 1	0.757
Jag1	jagged 1	0.751
Rarg	retinoic acid receptor, gamma	0.740
Gbx2	gastrulation brain homeobox 2	0.740
Lhx1	LIM homeobox protein 1	0.727
Vangl2	vang-like 2 (van gogh, Drosophila)	0.718
Smad1	MAD homolog 1 (Drosophila)	0.714	Mouse
Emx2	empty spiracles homolog 2 (Drosophila)	0.671
Wt1	Wilms tumor 1 homolog	0.649
Smad4	MAD homolog 4 (Drosophila)	0.647
Chrd	chordin	0.627
Sox2	SRY-box containing gene 2	0.613
Lmx1a	LIM homeobox transcription factor 1 alpha	0.539	Mouse
Vegfa	vascular endothelial growth factor A	0.527
Pax8	paired box gene 8	0.499
Smad6	MAD homolog 6 (Drosophila)	0.498	Mouse
Dlx5	distal-less homeobox 5	0.463
Gsc	goosecoid homeobox	0.428
Msx1	homeobox, msh-like 1	0.417
Hoxa3	homeobox A3	0.414
Msx2	homeobox, msh-like 2	0.405
Pax6	paired box gene 6	0.379
En1	engrailed 1	0.371
Meox2	mesenchyme homeobox 2	0.362
Otx1	orthodenticle homolog 1 (Drosophila)	0.358	Mouse
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.356
Gata6	GATA binding protein 6	0.316
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.316
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.305
Fgf10	fibroblast growth factor 10	0.304
Sall4	sal-like 4 (Drosophila)	0.289
Alx4	aristaless-like homeobox 4	0.283
Hoxa13	homeobox A13	0.279
Psen1	presenilin 1	0.274
Rb1	retinoblastoma 1	0.266
Tgfb2	transforming growth factor, beta 2	0.248
Pax9	paired box gene 9	0.243
Pou4f2	POU domain, class 4, transcription factor 2	0.224
Hes1	hairy and enhancer of split 1 (Drosophila)	0.215
Hoxd13	homeobox D13	0.202
Nkx2-1	NK2 homeobox 1	0.201
Foxa2	forkhead box A2	0.201
Gata3	GATA binding protein 3	0.200
Hmx3	H6 homeobox 3	0.199
Apc	adenomatosis polyposis coli	0.198
Pax1	paired box gene 1	0.183
Sox3	SRY-box containing gene 3	0.182
Efnb2	ephrin B2	0.177
Fgfr1	fibroblast growth factor receptor 1	0.166
Snai1	snail homolog 1 (Drosophila)	0.165
Rarb	retinoic acid receptor, beta	0.165
Notch1	Notch gene homolog 1 (Drosophila)	0.159
Uncx	UNC homeobox	0.158
Hoxd3	homeobox D3	0.153
Gdnf	glial cell line derived neurotrophic factor	0.149
Tlx3	T-cell leukemia, homeobox 3	0.145
Fgf3	fibroblast growth factor 3	0.145
Axin1	axin 1	0.145
Rxra	retinoid X receptor alpha	0.144
Emx1	empty spiracles homolog 1 (Drosophila)	0.137
Hmx1	H6 homeobox 1	0.136
T	brachyury	0.134	Mouse
Hoxd11	homeobox D11	0.130
Lmx1b	LIM homeobox transcription factor 1 beta	0.130	Mouse
Smo	smoothened homolog (Drosophila)	0.129
Foxb1	forkhead box B1	0.127
Hoxa2	homeobox A2	0.122
Hoxb6	homeobox B6	0.121
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.120
Lhx3	LIM homeobox protein 3	0.115	Mouse
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.113
Gdf1	growth differentiation factor 1	0.112	Mouse
Eomes	eomesodermin homolog (Xenopus laevis)	0.112	Mouse
Hoxa10	homeobox A10	0.109
Pitx3	paired-like homeodomain transcription factor 3	0.107
Dll3	delta-like 3 (Drosophila)	0.107
Sox11	SRY-box containing gene 11	0.099
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.098
Smad3	MAD homolog 3 (Drosophila)	0.097	Mouse
Acvr1	activin A receptor, type 1	0.097
Pou5f1	POU domain, class 5, transcription factor 1	0.093
Sox9	SRY-box containing gene 9	0.092
Runx2	runt related transcription factor 2	0.089
Myf5	myogenic factor 5	0.088
Bdnf	brain derived neurotrophic factor	0.087
Mesp1	mesoderm posterior 1	0.080	Mouse
Wnt3a	wingless-related MMTV integration site 3A	0.073
Tbx2	T-box 2	0.070	Mouse
Tcf21	transcription factor 21	0.070
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.070
Tgfbr2	transforming growth factor, beta receptor II	0.069
Tbx4	T-box 4	0.069	Mouse
Adam17	a disintegrin and metallopeptidase domain 17	0.069
Foxa1	forkhead box A1	0.067	Mouse
Wnt1	wingless-related MMTV integration site 1	0.065
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.065
Hes5	hairy and enhancer of split 5 (Drosophila)	0.064
Nkx3-2	NK3 homeobox 2	0.063
Hoxb3	homeobox B3	0.061
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.061
Irx3	Iroquois related homeobox 3 (Drosophila)	0.060
Insm1	insulinoma-associated 1	0.060
Erbb2ip	Erbb2 interacting protein	0.059
Ptch1	patched homolog 1	0.057
Gdf3	growth differentiation factor 3	0.057
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.056
Neurog2	neurogenin 2	0.055
Zeb1	zinc finger E-box binding homeobox 1	0.054
Lef1	lymphoid enhancer binding factor 1	0.053
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.052
Hoxa11	homeobox A11	0.052
Amhr2	anti-Mullerian hormone type 2 receptor	0.050
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.050
Foxf1a	forkhead box F1a	0.049
Lrp6	low density lipoprotein receptor-related protein 6	0.049
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.048
Lhx9	LIM homeobox protein 9	0.048	Mouse
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.046
Sox7	SRY-box containing gene 7	0.046
Dll4	delta-like 4 (Drosophila)	0.046
Pten	phosphatase and tensin homolog	0.045
Evx2	even skipped homeotic gene 2 homolog	0.044
Ntf3	neurotrophin 3	0.042
Hoxd9	homeobox D9	0.041
Alx3	aristaless-like homeobox 3	0.040
Pax7	paired box gene 7	0.039
Neurog1	neurogenin 1	0.039
Vax1	ventral anterior homeobox containing gene 1	0.039
Bmp7	bone morphogenetic protein 7	0.039
Fgf15	fibroblast growth factor 15	0.038
Hoxd1	homeobox D1	0.037
Matn3	matrilin 3	0.036
Pbx1	pre B-cell leukemia transcription factor 1	0.035
Hoxd10	homeobox D10	0.035
Alx1	ALX homeobox 1	0.035
Gli2	GLI-Kruppel family member GLI2	0.035
Dmrt3	doublesex and mab-3 related transcription factor 3	0.035
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.035
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.034
Rax	retina and anterior neural fold homeobox	0.034
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.034
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.034
Sox4	SRY-box containing gene 4	0.033
Tal2	T-cell acute lymphocytic leukemia 2	0.033
Lhx5	LIM homeobox protein 5	0.033	Mouse
Tdgf1	teratocarcinoma-derived growth factor 1	0.032
Evx1	even skipped homeotic gene 1 homolog	0.032
Hoxb13	homeobox B13	0.031
Dlx1	distal-less homeobox 1	0.031
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.030
Smad7	MAD homolog 7 (Drosophila)	0.030	Mouse
Smad2	MAD homolog 2 (Drosophila)	0.030	Mouse
Hoxb2	homeobox B2	0.030
Pou3f3	POU domain, class 3, transcription factor 3	0.030
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.030
Shox2	short stature homeobox 2	0.030
Fgfr3	fibroblast growth factor receptor 3	0.029
Tulp1	tubby like protein 1	0.029
Lrp2	low density lipoprotein receptor-related protein 2	0.029
Atoh1	atonal homolog 1 (Drosophila)	0.029
Hoxa9	homeobox A9	0.028
Hesx1	homeobox gene expressed in ES cells	0.028
Wnt9b	wingless-type MMTV integration site 9B	0.028
Sall3	sal-like 3 (Drosophila)	0.028
Egfr	epidermal growth factor receptor	0.028
Zic2	zinc finger protein of the cerebellum 2	0.028
Ece1	endothelin converting enzyme 1	0.027
Wnt3	wingless-related MMTV integration site 3	0.027
Foxf2	forkhead box F2	0.027
Rara	retinoic acid receptor, alpha	0.027
Hmga2	high mobility group AT-hook 2	0.027
Bnc1	basonuclin 1	0.026
Hoxb1	homeobox B1	0.026
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.025
Nanog	Nanog homeobox	0.025
En2	engrailed 2	0.025
Mecom	MDS1 and EVI1 complex locus	0.025
Cdx1	caudal type homeobox 1	0.025
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.025
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.025
Dlx2	distal-less homeobox 2	0.024
Lefty1	left right determination factor 1	0.024
Myod1	myogenic differentiation 1	0.024
Gja1	gap junction protein, alpha 1	0.024
Zic1	zinc finger protein of the cerebellum 1	0.024
Sox1	SRY-box containing gene 1	0.024
Hoxc6	homeobox C6	0.024
Cited2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.023
Notch2	Notch gene homolog 2 (Drosophila)	0.023
Fev	FEV (ETS oncogene family)	0.023
Sall1	sal-like 1 (Drosophila)	0.023
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.023
Ihh	Indian hedgehog	0.023
Robo3	roundabout homolog 3 (Drosophila)	0.023
Tead3	TEA domain family member 3	0.023
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.023
Col13a1	collagen, type XIII, alpha 1	0.023
Dbx1	developing brain homeobox 1	0.022
Cfc1	cripto, FRL-1, cryptic family 1	0.021
Pcdh12	protocadherin 12	0.021
Hoxa5	homeobox A5	0.021
Pthlh	parathyroid hormone-like peptide	0.021
Klf3	Kruppel-like factor 3 (basic)	0.021
Foxl2	forkhead box L2	0.021	Mouse
Efnb1	ephrin B1	0.021
Noto	notochord homolog (Xenopus laevis)	0.021
Rdh10	retinol dehydrogenase 10 (all-trans)	0.021
Prrx2	paired related homeobox 2	0.021
Twist2	twist homolog 2 (Drosophila)	0.021
Hoxb7	homeobox B7	0.020
Fgf4	fibroblast growth factor 4	0.020
Myf6	myogenic factor 6	0.020
Nes	nestin	0.020
Efna2	ephrin A2	0.020
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.020
Hoxb4	homeobox B4	0.020
Pou4f3	POU domain, class 4, transcription factor 3	0.020
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.020
Barx1	BarH-like homeobox 1	0.020
Cdkn2d	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.019	Mouse
Lhx4	LIM homeobox protein 4	0.019	Mouse
Myoz3	myozenin 3	0.019
Cga	glycoprotein hormones, alpha subunit	0.019
Zbtb46	zinc finger and BTB domain containing 46	0.019
Hmx2	H6 homeobox 2	0.019
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.019
Dhh	desert hedgehog	0.018
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.018
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.018
Neurod1	neurogenic differentiation 1	0.018
Cer1	cerberus 1 homolog (Xenopus laevis)	0.018
Etv2	ets variant gene 2	0.018
Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	0.018
Hoxb5	homeobox B5	0.018
Rnf2	ring finger protein 2	0.018
Tlx2	T-cell leukemia, homeobox 2	0.018
Sim1	single-minded homolog 1 (Drosophila)	0.017
Isl2	insulin related protein 2 (islet 2)	0.017	Mouse
Emid2	EMI domain containing 2	0.017
Tcf15	transcription factor 15	0.017
Foxd2	forkhead box D2	0.017	Mouse
Mip	major intrinsic protein of eye lens fiber	0.017
Ptk7	PTK7 protein tyrosine kinase 7	0.017
Foxe3	forkhead box E3	0.017	Mouse
Ighmbp2	immunoglobulin mu binding protein 2	0.017
Lrp5	low density lipoprotein receptor-related protein 5	0.017
Tal1	T-cell acute lymphocytic leukemia 1	0.017
Pyy	peptide YY	0.017
Col11a2	collagen, type XI, alpha 2	0.017
Dlx6	distal-less homeobox 6	0.017
Tead4	TEA domain family member 4	0.017
Hoxa4	homeobox A4	0.016
Tcl1	T-cell lymphoma breakpoint 1	0.016
Gata2	GATA binding protein 2	0.016
Magel2	melanoma antigen, family L, 2	0.016
Mnx1	motor neuron and pancreas homeobox 1	0.016
Hhex	hematopoietically expressed homeobox	0.016
Amh	anti-Mullerian hormone	0.016
Neurog3	neurogenin 3	0.016
Dll1	delta-like 1 (Drosophila)	0.016
Vstm2b	V-set and transmembrane domain containing 2B	0.015
Gata5	GATA binding protein 5	0.015
Osr1	odd-skipped related 1 (Drosophila)	0.015
Klf10	Kruppel-like factor 10	0.015
Il11	interleukin 11	0.015
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.015
Tcfap2c	transcription factor AP-2, gamma	0.015
Slc26a4	solute carrier family 26, member 4	0.014
Cyp26c1	cytochrome P450, family 26, subfamily c, polypeptide 1	0.014
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.014
Neurod4	neurogenic differentiation 4	0.014
Cxadr	coxsackie virus and adenovirus receptor	0.014
Irx5	Iroquois related homeobox 5 (Drosophila)	0.014
Myog	myogenin	0.014
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.014
Gsx2	GS homeobox 2	0.014
Phlda2	pleckstrin homology-like domain, family A, member 2	0.014
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.013
Flt4	FMS-like tyrosine kinase 4	0.013
Rnf111	ring finger 111	0.013
Eya4	eyes absent 4 homolog (Drosophila)	0.013
Cldn6	claudin 6	0.013
Jun	Jun oncogene	0.013
Prdm1	PR domain containing 1, with ZNF domain	0.013
Fst	follistatin	0.013
Pou3f4	POU domain, class 3, transcription factor 4	0.013
Cdc42	cell division cycle 42 homolog (S. cerevisiae)	0.013
Efna4	ephrin A4	0.013
Mn1	meningioma 1	0.013
Bik	BCL2-interacting killer	0.013
Ptf1a	pancreas specific transcription factor, 1a	0.013
Onecut1	one cut domain, family member 1	0.013
Bmpr2	bone morphogenic protein receptor, type II (serine/threonine kinase)	0.013
Hoxd12	homeobox D12	0.013
Wnt4	wingless-related MMTV integration site 4	0.013
Foxd1	forkhead box D1	0.012	Mouse
Insm2	insulinoma-associated 2	0.012
Hoxc8	homeobox C8	0.012
Ddx3y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked	0.012
Bptf	bromodomain PHD finger transcription factor	0.012
Wwtr1	WW domain containing transcription regulator 1	0.012
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.012
Nf1	neurofibromatosis 1	0.012
Wnt5a	wingless-related MMTV integration site 5A	0.012
Vgll2	vestigial like 2 homolog (Drosophila)	0.012
Nr0b1	nuclear receptor subfamily 0, group B, member 1	0.012
Lzts2	leucine zipper, putative tumor suppressor 2	0.012
Sim2	single-minded homolog 2 (Drosophila)	0.012
Ednra	endothelin receptor type A	0.012
Gsx1	GS homeobox 1	0.012
Cldn8	claudin 8	0.012
Inhbb	inhibin beta-B	0.012
Sox14	SRY-box containing gene 14	0.012
Inhbc	inhibin beta-C	0.012
Fgf6	fibroblast growth factor 6	0.012
Hes3	hairy and enhancer of split 3 (Drosophila)	0.012
Hmga1	high mobility group AT-hook 1	0.011
Rybp	RING1 and YY1 binding protein	0.011
Thsd1	thrombospondin, type I, domain 1	0.011
Figla	folliculogenesis specific basic helix-loop-helix	0.011
Nkx3-1	NK-3 transcription factor, locus 1 (Drosophila)	0.011
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.011
Acvr2b	activin receptor IIB	0.011
Wnt2b	wingless related MMTV integration site 2b	0.011
Wnt10b	wingless related MMTV integration site 10b	0.011
Spnb2	spectrin beta 2	0.011
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.011
Edar	ectodysplasin-A receptor	0.011
Cldn3	claudin 3	0.011
Sdcbp	syndecan binding protein	0.011
Fzd10	frizzled homolog 10 (Drosophila)	0.011
Wnt11	wingless-related MMTV integration site 11	0.011
Braf	Braf transforming gene	0.011
Eng	endoglin	0.010
Gsk3b	glycogen synthase kinase 3 beta	0.010
Aif1l	allograft inflammatory factor 1-like	0.010
Socs1	suppressor of cytokine signaling 1	0.010
Bach1	BTB and CNC homology 1	0.010
Hnf1b	HNF1 homeobox B	0.010
Atoh8	atonal homolog 8 (Drosophila)	0.010
Fgf16	fibroblast growth factor 16	0.010
Calcr	calcitonin receptor	0.010
Kiss1	KiSS-1 metastasis-suppressor	0.010
Cmtm8	CKLF-like MARVEL transmembrane domain containing 8	0.010
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.010
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.010