The network for 'phosphatidylinositol 3 kinase signaling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

phosphatidylinositol 3 kinase signaling

A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.

Homo sapiens
Name Description Probability Func Analog Organism
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 1.000
EGFR epidermal growth factor receptor 1.000
GRB2 growth factor receptor-bound protein 2 0.999
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.997
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.994
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.994
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.993
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.989
FYN FYN oncogene related to SRC, FGR, YES 0.987
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.978
SH3KBP1 SH3-domain kinase binding protein 1 0.971
CAV1 caveolin 1, caveolae protein, 22kDa 0.946
VEGFA vascular endothelial growth factor A 0.908
IRS1 insulin receptor substrate 1 0.885
INSR insulin receptor 0.881
IGF1R insulin-like growth factor 1 receptor 0.877
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.856
MPDZ multiple PDZ domain protein 0.852
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.842
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.774
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.754
PDCD6IP programmed cell death 6 interacting protein 0.695
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.674
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.616
ITCH itchy E3 ubiquitin protein ligase homolog (mouse) 0.599
CCL3 chemokine (C-C motif) ligand 3 0.593
GAB1 GRB2-associated binding protein 1 0.572
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.537
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.501
CCR5 chemokine (C-C motif) receptor 5 0.468
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.453
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.430
SH2D4A SH2 domain containing 4A 0.430
WIPF1 WAS/WASL interacting protein family, member 1 0.427
MET met proto-oncogene (hepatocyte growth factor receptor) 0.419
NRP1 neuropilin 1 0.404
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.334
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.318
MED28 mediator complex subunit 28 0.316
PLCG1 phospholipase C, gamma 1 0.298
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.277
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.274
SYK spleen tyrosine kinase 0.274
PTEN phosphatase and tensin homolog 0.245
GAB2 GRB2-associated binding protein 2 0.216
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.205
GRB10 growth factor receptor-bound protein 10 0.205
BLNK B-cell linker 0.203
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.200
LAT linker for activation of T cells 0.193
BCAR1 breast cancer anti-estrogen resistance 1 0.191
HCK hemopoietic cell kinase 0.190
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.188
RND1 Rho family GTPase 1 0.182
SLA Src-like-adaptor 0.171
GH1 growth hormone 1 0.166
TEK TEK tyrosine kinase, endothelial 0.164
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.158
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.158
PGF placental growth factor 0.154
CXCL9 chemokine (C-X-C motif) ligand 9 0.153
RICTOR RPTOR independent companion of MTOR, complex 2 0.150
IL1B interleukin 1, beta 0.149
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.139
ANGPT2 angiopoietin 2 0.137
IRS2 insulin receptor substrate 2 0.135
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.134
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.134
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.131
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 0.129
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.128
SOCS3 suppressor of cytokine signaling 3 0.118
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.116
TGFB3 transforming growth factor, beta 3 0.116
VAV2 vav 2 guanine nucleotide exchange factor 0.115
CCL2 chemokine (C-C motif) ligand 2 0.114
CSH2 chorionic somatomammotropin hormone 2 0.113
CCL4 chemokine (C-C motif) ligand 4 0.111
HDAC6 histone deacetylase 6 0.110
SMAD4 SMAD family member 4 0.110
BCR breakpoint cluster region 0.109
VAV3 vav 3 guanine nucleotide exchange factor 0.108
GRB7 growth factor receptor-bound protein 7 0.104
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.101
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.100
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.099
BTK Bruton agammaglobulinemia tyrosine kinase 0.095
SELE selectin E 0.093
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.093
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.093
SNX9 sorting nexin 9 0.089
CSHL1 chorionic somatomammotropin hormone-like 1 0.087
SPRR2A small proline-rich protein 2A 0.083
DARC Duffy blood group, chemokine receptor 0.082
GH2 growth hormone 2 0.081
PECAM1 platelet/endothelial cell adhesion molecule 0.081
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.079
IL6 interleukin 6 (interferon, beta 2) 0.078
CCR1 chemokine (C-C motif) receptor 1 0.078
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
gpr126 G protein-coupled receptor 126 0.623
nf1a neurofibromin 1a 0.612
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.576
erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog 0.362
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.329
col2a1a collagen type II, alpha-1a 0.258
nrp1a neuropilin 1a 0.234
tie2 endothelium-specific receptor tyrosine kinase 2 0.185
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.153
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.148
si:ch211-195h23.3 si:ch211-195h23.3 0.146
npnt nephronectin 0.134
card14 caspase recruitment domain family, member 14 0.133
flt4 fms-related tyrosine kinase 4 0.124
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.118
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.116
emx3 empty spiracles homeobox 3 0.111
tgfb3 transforming growth factor, beta 3 0.109
tp53bp2 tumor protein p53 binding protein, 2 0.109
disp1 dispatched homolog 1 (Drosophila) 0.105
hgfb hepatocyte growth factor b 0.104
vegfab vascular endothelial growth factor Ab 0.097
camk2g1 calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 1 0.096
pomt2 protein-O-mannosyltransferase 2 0.094
bmpr1ba bone morphogenetic protein receptor, type 1ba 0.093
skia nuclear oncoprotein skia 0.093
bnc2 basonuclin 2 0.090
sulf1 sulfatase 1 0.083
zgc:77714 zgc:77714 0.082
nf1b neurofibromin 1b 0.074
tie1 endothelium-specific receptor tyrosine kinase 1 0.071
si:dkey-8l13.4 si:dkey-8l13.4 0.068
ptgs1 prostaglandin-endoperoxide synthase 1 0.066
cd247l CD247 antigen like 0.066
nr2f5 nuclear receptor subfamily 2, group F, member 5 0.066
fgfr3 fibroblast growth factor receptor 3 0.066
si:dkeyp-50f5.1 si:dkeyp-50f5.1 0.064
LOC567384 interferon-induced protein with tetratricopeptide repeats 5-like 0.064
large like-glycosyltransferase 0.063
nkx2.3 NK2 transcription factor related 3 0.062
slc25a32a solute carrier family 25, member 32a 0.061
map1lc3a microtubule-associated protein 1 light chain 3 alpha 0.061
zgc:123282 zgc:123282 0.059
nkx2.1a NK2 homeobox 1a 0.059
nrg1 neuregulin 1 0.059
akt2 v-akt murine thymoma viral oncogene homolog 2 0.059
echs1 enoyl Coenzyme A hydratase, short chain, 1, mitochondrial 0.058
hadha hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase, alpha subunit 0.056
foxi1 forkhead box I1 0.055
nitr8 novel immune-type receptor 8 0.054
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.053
LOC555739 serine/threonine-protein kinase LMTK1-like 0.053
dnmt4 DNA (cytosine-5-)-methyltransferase 4 0.052
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.051
ankrd6 ankyrin repeat domain 6 0.051
igiv1s5 immunoglobulin light iota variable 1, s5 0.051
ifnphi1 interferon phi 1 0.051
pcmtd1 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 0.050
serpinf2 serine (or cysteine) peptidase inhibitor, clade F, member 2 0.049
ptpreb protein tyrosine phosphatase, receptor type, E, b 0.049
LOC795096 hypothetical protein LOC795096 0.049
ptk6a PTK6 protein tyrosine kinase 6a 0.049
pomt1 protein-O-mannosyltransferase 1 0.048
ocrl oculocerebrorenal syndrome of Lowe 0.047
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.047
inhbab inhibin, beta Ab 0.046
tnfrsf18 tumor necrosis factor receptor superfamily, member 18 0.046
LOC100001239 interferon-induced protein with tetratricopeptide repeats 5-like 0.046
efnb2a ephrin B2a 0.046
tiparp TCDD-inducible poly(ADP-ribose) polymerase 0.046
adora2b adenosine A2b receptor 0.045
amh anti-Mullerian hormone 0.044
nitr12 novel immune-type receptor 12 0.044
il10 interleukin 10 0.043
fshb follicle stimulating hormone, beta polypeptide 0.043
inhbb inhibin, beta B 0.043
c9 complement component 9 0.042
tyrobp TYRO protein tyrosine kinase binding protein 0.042
si:ch211-140f21.1 si:ch211-140f21.1 0.042
col5a3b collagen type V alpha-3b 0.042
evx1 even-skipped homeobox 1 0.041
sc:d812 sc:d812 0.041
lmx1b.2 LIM homeobox transcription factor 1, beta 2 0.041
illr4 immune-related, lectin-like receptor 4 0.041
illr1 immune-related, lectin-like receptor 1 0.040
ltk leukocyte tyrosine kinase 0.040
ihha Indian hedgehog homolog a 0.039
il6st interleukin 6 signal transducer 0.039
zbtb16a zinc finger and BTB domain containing 16a 0.039
spra sepiapterin reductase a 0.039
nitr5 novel immune-type receptor 5 and immune-type receptor 5-like 0.039
cd8a CD8 antigen, alpha polypeptide 0.039
styk1 serine/threonine/tyrosine kinase 1 0.038
antxr1 anthrax toxin receptor 1 0.038
si:ch211-235f6.2 si:ch211-235f6.2 0.038
vegfc vascular endothelial growth factor c 0.038
ahcy S-adenosylhomocysteine hydrolase 0.038
nitr4a novel immune-type receptor 4a 0.037
mbtps1 membrane-bound transcription factor protease, site 1 0.037
acat1 acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) 0.037
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Atg18 Autophagy-specific gene 18 0.169
chico CG5686 gene product from transcript CG5686-RB 0.120
ena enabled 0.102
lea leak 0.088
Pk61C Protein kinase 61C 0.086
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.083
jeb jelly belly 0.077
Tl Toll 0.071
NFAT NFAT homolog 0.064
Alk CG8250 gene product from transcript CG8250-RA 0.061
Atg2 Autophagy-specific gene 2 0.060
Stam Signal transducing adaptor molecule 0.058
S6k RPS6-p70-protein kinase 0.058
Wnk CG7177 gene product from transcript CG7177-RA 0.057
ex expanded 0.057
stai stathmin 0.054
step steppke 0.054
Pp2B-14D Protein phosphatase 2B at 14D 0.053
Atg8a Autophagy-specific gene 8a 0.047
wun wunen 0.047
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.044
Pi3K59F Phosphotidylinositol 3 kinase 59F 0.042
Pten CG5671 gene product from transcript CG5671-RB 0.041
Indy I'm not dead yet 0.040
kis kismet 0.040
dnc dunce 0.039
rst roughest 0.039
LIMK1 LIM-kinase1 0.038
oys oysgedart 0.038
Atg4 Autophagy-specific gene 4 0.032
drl derailed 0.032
baz bazooka 0.032
cher cheerio 0.030
Rheb CG1081 gene product from transcript CG1081-RA 0.030
tok tolkin 0.029
spi spitz 0.028
HLH106 Helix loop helix protein 106 0.028
Marf Mitochondrial assembly regulatory factor 0.028
cnc cap-n-collar 0.027
ems empty spiracles 0.027
Atg9 Autophagy-specific gene 9 0.027
myoglianin CG1838 gene product from transcript CG1838-RD 0.027
Pvr PDGF- and VEGF-receptor related 0.027
repo reversed polarity 0.027
klg klingon 0.027
tomosyn CG17762 gene product from transcript CG17762-RB 0.026
tutl turtle 0.026
X11L CG5675 gene product from transcript CG5675-RB 0.025
trio CG18214 gene product from transcript CG18214-RA 0.025
Cbl CG7037 gene product from transcript CG7037-RB 0.025
Akt1 CG4006 gene product from transcript CG4006-RA 0.025
CaMKII Calcium/calmodulin-dependent protein kinase II 0.024
Ephrin CG1862 gene product from transcript CG1862-RA 0.024
fra frazzled 0.024
Wnt5 Wnt oncogene analog 5 0.023
rut rutabaga 0.023
Eip71CD Ecdysone-induced protein 28/29kD 0.023
pdm3 pou domain motif 3 0.022
Atg7 Autophagy-specific gene 7 0.022
ImpL2 Ecdysone-inducible gene L2 0.022
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.022
trn tartan 0.022
Mob4 CG3403 gene product from transcript CG3403-RA 0.021
Nrx-IV Neurexin IV 0.020
jing CG9397 gene product from transcript CG9397-RI 0.020
scyl scylla 0.020
slbo slow border cells 0.020
Dcr-2 Dicer-2 0.020
CG12424 CG12424 gene product from transcript CG12424-RC 0.019
B-H1 BarH1 0.019
babo baboon 0.019
Fer2LCH Ferritin 2 light chain homologue 0.019
CG3004 CG3004 gene product from transcript CG3004-RA 0.019
Smox Smad on X 0.019
ird1 immune response deficient 1 0.019
Lrrk Leucine-rich repeat kinase 0.019
comt comatose 0.018
plexB plexin B 0.018
CG4699 CG4699 gene product from transcript CG4699-RJ 0.018
CG3573 CG3573 gene product from transcript CG3573-RA 0.018
Fak56D Focal Adhesion Kinase 0.018
lab labial 0.018
ap apterous 0.018
side sidestep 0.018
Nf1 Neurofibromin 1 0.018
TppII tripeptidyl-peptidase II 0.017
RASSF8 CG5053 gene product from transcript CG5053-RA 0.017
pkaap CG4132 gene product from transcript CG4132-RA 0.017
CG5731 CG5731 gene product from transcript CG5731-RA 0.017
Ptp52F CG18243 gene product from transcript CG18243-RB 0.017
chrb charybde 0.017
CG16778 CG16778 gene product from transcript CG16778-RA 0.016
CG5508 CG5508 gene product from transcript CG5508-RA 0.016
Krn Keren 0.016
CkIIalpha Casein kinase II alpha subunit 0.016
Fas3 Fasciclin 3 0.016
tld tolloid 0.016
Sema-1a CG18405 gene product from transcript CG18405-RD 0.016
Cul-5 Cullin-5 0.016
mbc myoblast city 0.016
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Mus musculus
Name Description Probability Func Analog Organism
Nos3 nitric oxide synthase 3, endothelial cell 0.908
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.665
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.570
Vegfa vascular endothelial growth factor A 0.540
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.524
Fyn Fyn proto-oncogene 0.484
Tgfb1 transforming growth factor, beta 1 0.478
Insr insulin receptor 0.425
Plcg1 phospholipase C, gamma 1 0.403
Nrp1 neuropilin 1 0.401
Grb10 growth factor receptor bound protein 10 0.395
Ret ret proto-oncogene 0.380
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.379
Efnb2 ephrin B2 0.352
Serpina10 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 0.337
Sox4 SRY-box containing gene 4 0.335
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.315
Lep leptin 0.288
Pax3 paired box gene 3 0.273
Ikzf1 IKAROS family zinc finger 1 0.255
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.246
Tgfb2 transforming growth factor, beta 2 0.234
Flt4 FMS-like tyrosine kinase 4 0.229
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.200
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.189
Fgfr2 fibroblast growth factor receptor 2 0.188
Rxra retinoid X receptor alpha 0.185
Lepr leptin receptor 0.180
Flt1 FMS-like tyrosine kinase 1 0.174
Ednrb endothelin receptor type B 0.172
Ptprb protein tyrosine phosphatase, receptor type, B 0.156
Nf1 neurofibromatosis 1 0.156
Tcf21 transcription factor 21 0.147
Inpp5d inositol polyphosphate-5-phosphatase D 0.146
Ntf3 neurotrophin 3 0.143
Kit kit oncogene 0.140
Cd22 CD22 antigen 0.139
Gata4 GATA binding protein 4 0.139
Gata6 GATA binding protein 6 0.137
Csf1 colony stimulating factor 1 (macrophage) 0.132
Gja4 gap junction protein, alpha 4 0.130
Fzd4 frizzled homolog 4 (Drosophila) 0.128
Pdgfb platelet derived growth factor, B polypeptide 0.127
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.123
Mefv Mediterranean fever 0.123
Dab1 disabled homolog 1 (Drosophila) 0.115
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.112
Socs1 suppressor of cytokine signaling 1 0.111
Kdr kinase insert domain protein receptor 0.103
Meox2 mesenchyme homeobox 2 0.100
She src homology 2 domain-containing transforming protein E 0.098
Egfr epidermal growth factor receptor 0.098
Btk Bruton agammaglobulinemia tyrosine kinase 0.093
Tbx21 T-box 21 0.090
Blk B lymphoid kinase 0.090
Nrg1 neuregulin 1 0.088
Ece1 endothelin converting enzyme 1 0.088
Pten phosphatase and tensin homolog 0.088
Slamf1 signaling lymphocytic activation molecule family member 1 0.086
Hdac7 histone deacetylase 7 0.085
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.083
Bcar1 breast cancer anti-estrogen resistance 1 0.082
Dok3 docking protein 3 0.082
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.081
Ephb2 Eph receptor B2 0.079
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.079
Csf1r colony stimulating factor 1 receptor 0.078
Prf1 perforin 1 (pore forming protein) 0.078
Irf5 interferon regulatory factor 5 0.078
Cd19 CD19 antigen 0.077
Trpv1 transient receptor potential cation channel, subfamily V, member 1 0.077
Cxcl12 chemokine (C-X-C motif) ligand 12 0.076
Ednra endothelin receptor type A 0.075
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.073
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.072
Tsc1 tuberous sclerosis 1 0.071
Bcl2 B-cell leukemia/lymphoma 2 0.071
Grb2 growth factor receptor bound protein 2 0.071
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.069
Zeb1 zinc finger E-box binding homeobox 1 0.068
Pzp pregnancy zone protein 0.068
Trp53 transformation related protein 53 0.067
Cd4 CD4 antigen 0.066
Chd7 chromodomain helicase DNA binding protein 7 0.066
Sox7 SRY-box containing gene 7 0.065
Sdc3 syndecan 3 0.064
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.064
Treml1 triggering receptor expressed on myeloid cells-like 1 0.064
Fgf10 fibroblast growth factor 10 0.063
Lipc lipase, hepatic 0.063
Vav2 vav 2 oncogene 0.062
Pou2f2 POU domain, class 2, transcription factor 2 0.062
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.062
Nynrin NYN domain and retroviral integrase containing 0.061
Isl1 ISL1 transcription factor, LIM/homeodomain 0.060
Hs1bp3 HCLS1 binding protein 3 0.059
Ccr6 chemokine (C-C motif) receptor 6 0.059
Icos inducible T-cell co-stimulator 0.059
Efnb1 ephrin B1 0.059
F10 coagulation factor X 0.059
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ddr1 discoidin domain receptor tyrosine kinase 1 0.119
Il1b interleukin 1 beta 0.067
Met met proto-oncogene 0.063
Fgfr2 fibroblast growth factor receptor 2 0.062
Cfp complement factor properdin 0.051
Flt1 FMS-related tyrosine kinase 1 0.049
Prrx1 paired related homeobox 1 0.048
Ralgds ral guanine nucleotide dissociation stimulator 0.047
Strn striatin, calmodulin binding protein 0.045
Hck hemopoietic cell kinase 0.044
Cd86 CD86 molecule 0.044
Adrbk1 adrenergic, beta, receptor kinase 1 0.044
Ccl2 chemokine (C-C motif) ligand 2 0.040
Ptafr platelet-activating factor receptor 0.040
Tef thyrotrophic embryonic factor 0.036
Dbp D site of albumin promoter (albumin D-box) binding protein 0.036
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.034
Ccl4 chemokine (C-C motif) ligand 4 0.034
Gja1 gap junction protein, alpha 1 0.032
Ccr5 chemokine (C-C motif) receptor 5 0.032
Il2rb interleukin 2 receptor, beta 0.031
Nab1 Ngfi-A binding protein 1 0.029
Ccl3 chemokine (C-C motif) ligand 3 0.028
LOC100364485 mCG1051031-like 0.027
Il1a interleukin 1 alpha 0.027
Cd8a CD8a molecule 0.027
Nos3 nitric oxide synthase 3, endothelial cell 0.026
Zfp36l1 zinc finger protein 36, C3H type-like 1 0.026
Epn1 Epsin 1 0.026
Prf1 perforin 1 (pore forming protein) 0.026
Med25 mediator complex subunit 25 0.026
Pftk1 PFTAIRE protein kinase 1 0.025
Adora2a adenosine A2a receptor 0.024
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.023
Nxph1 neurexophilin 1 0.023
Ptprc protein tyrosine phosphatase, receptor type, C 0.023
Agtr1a angiotensin II receptor, type 1a 0.022
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.022
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.022
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.021
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.020
Dock8 dedicator of cytokinesis 8 0.020
Pcnxl3 pecanex-like 3 (Drosophila) 0.020
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.019
Ptms parathymosin 0.019
Mprip myosin phosphatase Rho interacting protein 0.019
Grm3 glutamate receptor, metabotropic 3 0.019
Fosl1 fos-like antigen 1 0.019
Pou2f2 POU class 2 homeobox 2 0.019
Casp3 caspase 3 0.018
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.018
Fgf18 fibroblast growth factor 18 0.018
Fgf7 fibroblast growth factor 7 0.017
Ifng interferon gamma 0.017
Insr insulin receptor 0.016
Man2a1 mannosidase, alpha, class 2A, member 1 0.016
Ptprs protein tyrosine phosphatase, receptor type, S 0.016
Il6 interleukin 6 0.016
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.015
Gabra3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.015
Prkcd protein kinase C, delta 0.015
Sycn syncollin 0.015
Jak1 Janus kinase 1 0.015
Gzmk granzyme K 0.015
Syt6 synaptotagmin VI 0.014
Palm paralemmin 0.014
Cdh6 cadherin 6 0.014
Socs3 suppressor of cytokine signaling 3 0.014
Npr1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 0.014
Ccl5 chemokine (C-C motif) ligand 5 0.013
Nfib nuclear factor I/B 0.013
Emcn endomucin 0.013
Clcn5 chloride channel 5 0.013
Irs3 insulin receptor substrate 3 0.013
Zbp1 Z-DNA binding protein 1 0.013
Plcb2 phospholipase C, beta 2 0.013
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.013
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.013
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.013
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.013
Krt4 keratin 4 0.013
Sla src-like adaptor 0.013
Gabra1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.012
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.012
Gpr176 G protein-coupled receptor 176 0.012
Mmp3 matrix metallopeptidase 3 0.012
Cga glycoprotein hormones, alpha polypeptide 0.012
Sash3 SAM and SH3 domain containing 3 0.012
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.012
Arhgap4 Rho GTPase activating protein 4 0.012
Usf2 upstream transcription factor 2, c-fos interacting 0.012
Pawr PRKC, apoptosis, WT1, regulator 0.012
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.012
Wipf1 WAS/WASL interacting protein family, member 1 0.012
Il18 interleukin 18 0.012
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.012
Htr2b 5-hydroxytryptamine (serotonin) receptor 2B 0.012
Gria2 glutamate receptor, ionotropic, AMPA 2 0.012
RGD1309414 similar to KIAA0913 protein 0.012
Itpr3 inositol 1,4,5-triphosphate receptor, type 3 0.012
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism