The network for 'regulation of calcium ion transport into cytosol' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of calcium ion transport into cytosol

Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.

Mus musculus
Name Description Probability Func Analog Organism
Igh immunoglobulin heavy chain complex 0.996
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.903
Src Rous sarcoma oncogene 0.887
Was Wiskott-Aldrich syndrome homolog (human) 0.819
Pten phosphatase and tensin homolog 0.798
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.743
Cd79a CD79A antigen (immunoglobulin-associated alpha) 0.738
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.649
Bax BCL2-associated X protein 0.568
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.526
Trp53 transformation related protein 53 0.469
Ikzf1 IKAROS family zinc finger 1 0.459
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.397
Pxn paxillin 0.389
Grb2 growth factor receptor bound protein 2 0.357
Stat6 signal transducer and activator of transcription 6 0.314
Ptk2 PTK2 protein tyrosine kinase 2 0.296
Vegfa vascular endothelial growth factor A 0.290
Foxc1 forkhead box C1 0.289
Bcl2 B-cell leukemia/lymphoma 2 0.288
Ldb3 LIM domain binding 3 0.286
Cbl Casitas B-lineage lymphoma 0.284
Skil SKI-like 0.265
Prkcb protein kinase C, beta 0.247
Bdnf brain derived neurotrophic factor 0.243
Srpk3 serine/arginine-rich protein specific kinase 3 0.231
Actn2 actinin alpha 2 0.230
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.226
Bcar1 breast cancer anti-estrogen resistance 1 0.218
Cd19 CD19 antigen 0.217
Prkcc protein kinase C, gamma 0.206
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.194
Inpp5d inositol polyphosphate-5-phosphatase D 0.178
Ptprc protein tyrosine phosphatase, receptor type, C 0.173
ND6 NADH dehydrogenase subunit 6 0.171
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.169
Kit kit oncogene 0.154
Cd22 CD22 antigen 0.154
Esr2 estrogen receptor 2 (beta) 0.148
Vhl von Hippel-Lindau tumor suppressor 0.146
Hmha1 histocompatibility (minor) HA-1 0.143
Sgcg sarcoglycan, gamma (dystrophin-associated glycoprotein) 0.138
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.137
Ccr6 chemokine (C-C motif) receptor 6 0.136
Sgca sarcoglycan, alpha (dystrophin-associated glycoprotein) 0.133
Coro1b coronin, actin binding protein 1B 0.132
Icos inducible T-cell co-stimulator 0.125
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.123
Mapk3 mitogen-activated protein kinase 3 0.119
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.115
Prrx1 paired related homeobox 1 0.114
Plcg2 phospholipase C, gamma 2 0.111
Hcls1 hematopoietic cell specific Lyn substrate 1 0.111
Capzb capping protein (actin filament) muscle Z-line, beta 0.110
Fyn Fyn proto-oncogene 0.109
Ric8 resistance to inhibitors of cholinesterase 8 homolog (C. elegans) 0.108
Zeb1 zinc finger E-box binding homeobox 1 0.107
Lmna lamin A 0.106
Ptpre protein tyrosine phosphatase, receptor type, E 0.105
Fas Fas (TNF receptor superfamily member 6) 0.105
Gata4 GATA binding protein 4 0.104
Fyb FYN binding protein 0.103
Ptrf polymerase I and transcript release factor 0.102
Rhog ras homolog gene family, member G 0.097
Cd209d CD209d antigen 0.095
Cd209b CD209b antigen 0.092
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.091
Ryr2 ryanodine receptor 2, cardiac 0.090
Spib Spi-B transcription factor (Spi-1/PU.1 related) 0.087
Casq2 calsequestrin 2 0.087
Ncoa3 nuclear receptor coactivator 3 0.087
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.085
Dok1 docking protein 1 0.085
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.084
Scn5a sodium channel, voltage-gated, type V, alpha 0.083
Siglec1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.083
Dnm1 dynamin 1 0.081
Ctnnb1 catenin (cadherin associated protein), beta 1 0.081
Itgb2 integrin beta 2 0.081
Cd4 CD4 antigen 0.080
Ostf1 osteoclast stimulating factor 1 0.079
Msr1 macrophage scavenger receptor 1 0.077
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.076
Necap2 NECAP endocytosis associated 2 0.076
Csf1 colony stimulating factor 1 (macrophage) 0.074
Sh3bgr SH3-binding domain glutamic acid-rich protein 0.074
Msx1 homeobox, msh-like 1 0.073
Uts2r urotensin 2 receptor 0.072
Fcgr2b Fc receptor, IgG, low affinity IIb 0.071
0610031J06Rik RIKEN cDNA 0610031J06 gene 0.070
Cr2 complement receptor 2 0.069
Mfn2 mitofusin 2 0.068
Chrd chordin 0.068
Adrbk1 adrenergic receptor kinase, beta 1 0.067
Cox6a2 cytochrome c oxidase, subunit VI a, polypeptide 2 0.066
Nf1 neurofibromatosis 1 0.066
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.065
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.064
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.063
Spna2 spectrin alpha 2 0.062
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.018
foxa1 forkhead box A1 0.016
nkx2.2a NK2 transcription factor related 2a 0.015
dbx1a developing brain homeobox 1a 0.014
pax6a paired box gene 6a 0.014
olig2 oligodendrocyte lineage transcription factor 2 0.014
foxa3 forkhead box A3 0.013
wnt8b wingless-type MMTV integration site family, member 8b 0.012
hoxb1b homeo box B1b 0.012
otx2 orthodenticle homolog 2 0.012
isl1 islet1 0.012
irx1b iroquois homeobox protein 1, b 0.012
fezf2 FEZ family zinc finger 2 0.011
esr2a estrogen receptor 2a 0.011
pax2a paired box gene 2a 0.011
sox9b SRY-box containing gene 9b 0.011
ascl1a achaete-scute complex-like 1a (Drosophila) 0.011
neurog1 neurogenin 1 0.011
her8a hairy-related 8a 0.011
barhl2 BarH-like 2 0.010
pax3a paired box gene 3a 0.010
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.010
sox19a SRY-box containing gene 19a 0.010
meis2.1 myeloid ecotropic viral integration site 2.1 0.010
arx aristaless related homeobox 0.010
bmp4 bone morphogenetic protein 4 0.010
LOC565632 BTB/POZ domain-containing protein 16-like 0.010
ascl1b achaete-scute complex-like 1b (Drosophila) 0.010
pou3f1 POU class 3 homeobox 1 0.010
met met proto-oncogene (hepatocyte growth factor receptor) 0.010
LOC100330335 uncharacterized protein C8orf74 homolog 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
GSTM1 glutathione S-transferase mu 1 0.999
CCL5 chemokine (C-C motif) ligand 5 0.998
GSTM2 glutathione S-transferase mu 2 (muscle) 0.992
CXCL9 chemokine (C-X-C motif) ligand 9 0.983
IL8 interleukin 8 0.974
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.939
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.913
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.908
CXCL3 chemokine (C-X-C motif) ligand 3 0.838
TTN titin 0.825
MPDZ multiple PDZ domain protein 0.810
CXCL5 chemokine (C-X-C motif) ligand 5 0.788
CXCL2 chemokine (C-X-C motif) ligand 2 0.785
CCR2 chemokine (C-C motif) receptor 2 0.779
CCL2 chemokine (C-C motif) ligand 2 0.774
BCL2L1 BCL2-like 1 0.750
KIAA1683 KIAA1683 0.729
CCL7 chemokine (C-C motif) ligand 7 0.693
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.669
IL1B interleukin 1, beta 0.666
IL6 interleukin 6 (interferon, beta 2) 0.658
CCL8 chemokine (C-C motif) ligand 8 0.656
GSTM4 glutathione S-transferase mu 4 0.650
IFNG interferon, gamma 0.644
CCR4 chemokine (C-C motif) receptor 4 0.640
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3 0.581
CCL4 chemokine (C-C motif) ligand 4 0.568
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.554
CCL20 chemokine (C-C motif) ligand 20 0.530
CCL22 chemokine (C-C motif) ligand 22 0.504
CCR7 chemokine (C-C motif) receptor 7 0.492
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.425
DPP4 dipeptidyl-peptidase 4 0.382
IL10 interleukin 10 0.377
CCL3 chemokine (C-C motif) ligand 3 0.362
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.327
CXCL10 chemokine (C-X-C motif) ligand 10 0.310
CXCL13 chemokine (C-X-C motif) ligand 13 0.304
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.296
TGFBR1 transforming growth factor, beta receptor 1 0.288
CXCL11 chemokine (C-X-C motif) ligand 11 0.282
CCR1 chemokine (C-C motif) receptor 1 0.278
MAPT microtubule-associated protein tau 0.268
CXCR3 chemokine (C-X-C motif) receptor 3 0.257
IL2RB interleukin 2 receptor, beta 0.251
BAK1 BCL2-antagonist/killer 1 0.243
GRB2 growth factor receptor-bound protein 2 0.239
ACVR1B activin A receptor, type IB 0.233
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.223
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.221
DTNA dystrobrevin, alpha 0.201
CD22 CD22 molecule 0.199
TNF tumor necrosis factor 0.196
ARRB2 arrestin, beta 2 0.195
SKIL SKI-like oncogene 0.187
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.171
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.170
IRF4 interferon regulatory factor 4 0.152
RGS1 regulator of G-protein signaling 1 0.151
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.144
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.143
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.141
RNR2 l-rRNA 0.139
PRKCD protein kinase C, delta 0.136
RNF144B ring finger protein 144B 0.134
EPOR erythropoietin receptor 0.133
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.132
ATG3 ATG3 autophagy related 3 homolog (S. cerevisiae) 0.131
PSEN2 presenilin 2 (Alzheimer disease 4) 0.127
CCL13 chemokine (C-C motif) ligand 13 0.124
CLEC7A C-type lectin domain family 7, member A 0.122
SLAMF7 SLAM family member 7 0.119
CCL19 chemokine (C-C motif) ligand 19 0.117
SYK spleen tyrosine kinase 0.115
MATK megakaryocyte-associated tyrosine kinase 0.113
IL10RA interleukin 10 receptor, alpha 0.110
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.108
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.106
APP amyloid beta (A4) precursor protein 0.106
AKAP6 A kinase (PRKA) anchor protein 6 0.106
ALB albumin 0.105
CD40LG CD40 ligand 0.105
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.102
CD79A CD79a molecule, immunoglobulin-associated alpha 0.100
PRKCA protein kinase C, alpha 0.096
ATG12 ATG12 autophagy related 12 homolog (S. cerevisiae) 0.094
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.093
SOCS3 suppressor of cytokine signaling 3 0.093
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.091
ARRB1 arrestin, beta 1 0.089
RHOA ras homolog gene family, member A 0.089
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.085
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.083
BCL2A1 BCL2-related protein A1 0.081
SPTBN1 spectrin, beta, non-erythrocytic 1 0.081
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.080
EHD1 EH-domain containing 1 0.079
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.078
SYNM synemin, intermediate filament protein 0.076
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Rattus norvegicus
Name Description Probability Func Analog Organism
Ptprc protein tyrosine phosphatase, receptor type, C 0.091
Sirpa signal-regulatory protein alpha 0.073
Ly86 lymphocyte antigen 86 0.070
Calcrl calcitonin receptor-like 0.062
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.056
Il2rg interleukin 2 receptor, gamma 0.048
Casp1 caspase 1 0.039
Chrm2 cholinergic receptor, muscarinic 2 0.038
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 0.038
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.037
Aqp4 aquaporin 4 0.034
Ptgfr prostaglandin F receptor 0.033
Csf1 colony stimulating factor 1 (macrophage) 0.033
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.033
Fgf16 fibroblast growth factor 16 0.031
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.030
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.029
Gzmk granzyme K 0.029
Hcrtr2 hypocretin (orexin) receptor 2 0.028
Gja6 gap junction protein, alpha 6 0.027
Slc22a25 solute carrier family 22, member 25 0.027
Prdx1 peroxiredoxin 1 0.027
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.026
Cd4 Cd4 molecule 0.026
Pde1c phosphodiesterase 1C 0.026
Hpgds hematopoietic prostaglandin D synthase 0.026
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.026
Cd3g CD3 molecule, gamma 0.025
Syt7 synaptotagmin VII 0.025
Phkg1 phosphorylase kinase, gamma 1 0.025
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.024
Pftk1 PFTAIRE protein kinase 1 0.022
Dchs1 dachsous 1 (Drosophila) 0.022
RGD1559588 similar to cell surface receptor FDFACT 0.022
Lcp2 lymphocyte cytosolic protein 2 0.022
Cd86 CD86 molecule 0.022
Ccr5 chemokine (C-C motif) receptor 5 0.022
Dock8 dedicator of cytokinesis 8 0.021
Cd247 Cd247 molecule 0.021
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.021
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.021
Cybb cytochrome b-245, beta polypeptide 0.020
Myo9a myosin IXA 0.020
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.020
Gimap4 GTPase, IMAP family member 4 0.020
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.020
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.019
Hck hemopoietic cell kinase 0.019
Sla src-like adaptor 0.019
Pkia protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.019
Inpp5d inositol polyphosphate-5-phosphatase D 0.019
Ndufa6 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14) 0.018
Tcf4 transcription factor 4 0.018
Acp5 acid phosphatase 5, tartrate resistant 0.018
Grm7 glutamate receptor, metabotropic 7 0.018
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.018
Ednra endothelin receptor type A 0.018
Arrb2 arrestin, beta 2 0.017
Ucp3 uncoupling protein 3 (mitochondrial, proton carrier) 0.017
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 0.017
Cxcl13 chemokine (C-X-C motif) ligand 13 0.017
Cd53 Cd53 molecule 0.017
Kif6 kinesin family member 6 0.017
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.016
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.016
Pcyt1b phosphate cytidylyltransferase 1, choline, beta 0.016
Slc15a3 solute carrier family 15, member 3 0.016
Cacng1 calcium channel, voltage-dependent, gamma subunit 1 0.016
Ampd1 adenosine monophosphate deaminase 1 (isoform M) 0.016
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.015
Nfasc neurofascin 0.015
Col12a1 collagen, type XII, alpha 1 0.015
Utrn utrophin 0.015
Trhr thyrotropin releasing hormone receptor 0.015
Cd37 CD37 molecule 0.014
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.014
Pld2 phospholipase D2 0.014
Emcn endomucin 0.014
F13a1 coagulation factor XIII, A1 polypeptide 0.014
Il2rb interleukin 2 receptor, beta 0.014
Il9r interleukin 9 receptor 0.014
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.014
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.014
Sdc3 syndecan 3 0.014
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.014
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.014
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.014
Podxl podocalyxin-like 0.014
Cntfr ciliary neurotrophic factor receptor 0.014
Pycard PYD and CARD domain containing 0.014
Nrxn1 neurexin 1 0.014
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 0.014
Mylk2 myosin light chain kinase 2 0.014
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.014
MGC112715 hypothetical protein LOC690899 0.013
Ptprs protein tyrosine phosphatase, receptor type, S 0.013
Hcst hematopoietic cell signal transducer 0.013
Galr2 galanin receptor 2 0.013
Abcc8 ATP-binding cassette, subfamily C (CFTR/MRP), member 8 0.013
Cd38 CD38 molecule 0.013
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism