The network for 'homeostasis of number of cells' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

homeostasis of number of cells

Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.

Name Description Probability Func Analog Organism
Ank1 ankyrin 1, erythroid 0.999
Spna1 spectrin alpha 1 0.999
Hbb-b1 hemoglobin, beta adult major chain 0.999
Pten phosphatase and tensin homolog 0.994
Epor erythropoietin receptor 0.992
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.990
Gata1 GATA binding protein 1 0.987
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.986
Shh sonic hedgehog 0.985
Slc4a1 solute carrier family 4 (anion exchanger), member 1 0.983
Smad4 MAD homolog 4 (Drosophila) 0.982
Igh immunoglobulin heavy chain complex 0.982
Trp53 transformation related protein 53 0.971
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.969
Ikzf1 IKAROS family zinc finger 1 0.958
Spnb1 spectrin beta 1 0.953
Hoxa5 homeobox A5 0.946
Gata4 GATA binding protein 4 0.943
Il2rg interleukin 2 receptor, gamma chain 0.935
Lyz2 lysozyme 2 0.930
Rarg retinoic acid receptor, gamma 0.929
Rxra retinoid X receptor alpha 0.928
Tcf3 transcription factor 3 0.913
Chuk conserved helix-loop-helix ubiquitous kinase 0.912
Gata6 GATA binding protein 6 0.911
Klf1 Kruppel-like factor 1 (erythroid) 0.908
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.902
Sox4 SRY-box containing gene 4 0.892
Mcl1 myeloid cell leukemia sequence 1 0.890
Ctnnb1 catenin (cadherin associated protein), beta 1 0.873
Kit kit oncogene 0.871
Mapk14 mitogen-activated protein kinase 14 0.863
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.849
Tgfbr2 transforming growth factor, beta receptor II 0.846
Mdm2 transformed mouse 3T3 cell double minute 2 0.841
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.826
Spnb2 spectrin beta 2 0.824
Cbl Casitas B-lineage lymphoma 0.820
Add2 adducin 2 (beta) 0.818
Smad7 MAD homolog 7 (Drosophila) 0.817
Hbb-b2 hemoglobin, beta adult minor chain 0.817
Tgfb2 transforming growth factor, beta 2 0.816
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.802
Cd19 CD19 antigen 0.785
Msh2 mutS homolog 2 (E. coli) 0.782
Gypa glycophorin A 0.780
Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 0.778
Acvr1 activin A receptor, type 1 0.778
Ptprc protein tyrosine phosphatase, receptor type, C 0.777
Exoc6 exocyst complex component 6 0.775
Ptch1 patched homolog 1 0.773
Fgfr2 fibroblast growth factor receptor 2 0.770
Epas1 endothelial PAS domain protein 1 0.768
Hif1a hypoxia inducible factor 1, alpha subunit 0.767
Vhl von Hippel-Lindau tumor suppressor 0.762
Foxp1 forkhead box P1 0.760
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.759
Hoxa9 homeobox A9 0.758
Cd40 CD40 antigen 0.757
Pbx1 pre B-cell leukemia transcription factor 1 0.745
Ikbkg inhibitor of kappaB kinase gamma 0.742
Runx1 runt related transcription factor 1 0.735
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.733
Il6st interleukin 6 signal transducer 0.729
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.717
Stat3 signal transducer and activator of transcription 3 0.713
Notch2 Notch gene homolog 2 (Drosophila) 0.696
Hoxb3 homeobox B3 0.696
Ciita class II transactivator 0.695
Tlr4 toll-like receptor 4 0.694
Mapk8 mitogen-activated protein kinase 8 0.691
Hand1 heart and neural crest derivatives expressed transcript 1 0.691
Myd88 myeloid differentiation primary response gene 88 0.683
Hes1 hairy and enhancer of split 1 (Drosophila) 0.677
Arid4a AT rich interactive domain 4A (RBP1-like) 0.677
Meox2 mesenchyme homeobox 2 0.674
Hoxb5 homeobox B5 0.668
Hoxd13 homeobox D13 0.667
Bmp4 bone morphogenetic protein 4 0.663
Hoxd3 homeobox D3 0.654
Jak2 Janus kinase 2 0.642
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 0.641
Vegfa vascular endothelial growth factor A 0.639
Tal1 T-cell acute lymphocytic leukemia 1 0.636
Isl1 ISL1 transcription factor, LIM/homeodomain 0.629
Tsc2 tuberous sclerosis 2 0.625
Apc adenomatosis polyposis coli 0.625
Hoxa1 homeobox A1 0.613
Rarb retinoic acid receptor, beta 0.604
Gmnn geminin 0.604
Gata5 GATA binding protein 5 0.603
Pax2 paired box gene 2 0.603
Nf1 neurofibromatosis 1 0.602
Tcf21 transcription factor 21 0.595
Sh2b3 SH2B adaptor protein 3 0.585
Smad1 MAD homolog 1 (Drosophila) 0.585
Tgfbr1 transforming growth factor, beta receptor I 0.581
Lef1 lymphoid enhancer binding factor 1 0.581
Foxd2 forkhead box D2 0.568
Hoxb4 homeobox B4 0.568
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
tbx5a T-box 5a 0.968
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.931
tfr1a transferrin receptor 1a 0.930
hbbe1.1 hemoglobin beta embryonic-1.1 0.929
LOC566708 FL cytokine receptor-like 0.923
ikzf1 IKAROS family zinc finger 1 (Ikaros) 0.914
alas2 aminolevulinate, delta-, synthetase 2 0.884
pitx2 paired-like homeodomain transcription factor 2 0.775
LOC100151531 zinc finger protein Gfi-1b-like 0.753
gata1a GATA binding protein 1a 0.661
gfi1.1 growth factor independent 1.1 0.634
nkx2.5 NK2 transcription factor related 5 0.583
tal1 T-cell acute lymphocytic leukemia 1 0.579
hbae3 hemoglobin alpha embryonic-3 0.571
epor erythropoietin receptor 0.556
ttna titin a 0.551
plcg1 phospholipase C, gamma 1 0.501
tgfb3 transforming growth factor, beta 3 0.470
rpl23a ribosomal protein L23a 0.468
pax2a paired box gene 2a 0.438
hand2 heart and neural crest derivatives expressed transcript 2 0.434
epb41 erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked) 0.434
hoxd4a homeo box D4a 0.425
rpl9 ribosomal protein L9 0.421
hoxb5b homeo box B5b 0.418
cfl2l cofilin 2, like 0.412
runx1 runt-related transcription factor 1 0.402
fli1a friend leukemia integration 1a 0.385
il7r interleukin 7 receptor 0.366
igfbp3 insulin-like growth factor binding protein 3 0.355
neurog1 neurogenin 1 0.352
mib mind bomb 0.332
mpx myeloid-specific peroxidase 0.331
isl1 islet1 0.327
alcama activated leukocyte cell adhesion molecule a 0.313
lyz lysozyme 0.307
gata6 GATA-binding protein 6 0.263
kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 0.256
adora2aa adenosine A2a receptor a 0.254
cbfb core-binding factor, beta subunit 0.245
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.235
runx3 runt-related transcription factor 3 0.233
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.233
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.231
foxc1a forkhead box C1a 0.228
tspo translocator protein 0.225
spaw southpaw 0.214
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.214
sox7 SRY-box containing gene 7 0.203
tpm4 tropomyosin 4 0.202
ryr1b ryanodine receptor 1b (skeletal) 0.198
si:dkeyp-66d7.2 si:dkeyp-66d7.2 0.195
robo4 roundabout homolog 4 0.188
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.185
cebp1 CCAAT/enhancer binding protein (C/EBP) 1 0.185
hdr hematopoietic death receptor 0.185
notch1b notch homolog 1b 0.179
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.178
sptb spectrin, beta, erythrocytic 0.177
prdm1a PR domain containing 1a, with ZNF domain 0.175
lmo2 LIM domain only 2 (rhombotin-like 1) 0.174
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.173
smchd1 structural maintenance of chromosomes flexible hinge domain containing 1 0.170
hmga1a high mobility group AT-hook 1a 0.168
cmyb transcription factor cmyb 0.167
rarga retinoic acid receptor gamma a 0.166
hbbe3 hemoglobin beta embryonic-3 0.165
fgf10a fibroblast growth factor 10a 0.158
mll myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) 0.155
hbbe2 hemoglobin beta embryonic-2 0.155
lcp1 lymphocyte cytosolic plastin 1 0.155
dlc deltaC 0.153
bmp2b bone morphogenetic protein 2b 0.151
ncor1 nuclear receptor co-repressor 1 0.151
cbln1 cerebellin 1 precursor 0.150
smyd3 SET and MYND domain containing 3 0.149
rpl36a ribosomal protein L36A 0.148
tbx18 T-box 18 0.146
mef2a myocyte enhancer factor 2a 0.141
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.138
smc3 structural maintenance of chromosomes 3 0.137
tbx1 T-box 1 0.133
cdx4 caudal type homeo box transcription factor 4 0.132
si:ch211-235f6.2 si:ch211-235f6.2 0.131
myl7 myosin, light polypeptide 7, regulatory 0.130
nppa natriuretic peptide precursor A 0.129
plagl2 pleiomorphic adenoma gene-like 2 0.128
dharma dharma 0.123
rhag Rhesus blood group-associated glycoprotein 0.121
sgcd sarcoglycan, delta (dystrophin-associated glycoprotein) 0.121
hbaa1 hemoglobin alpha adult-1 0.121
tp53 tumor protein p53 0.119
tbx24 T-box 24 0.119
aplnrb apelin receptor b 0.118
rpl13a ribosomal protein L13a 0.117
igf1 insulin-like growth factor 1 0.116
acvr2b activin receptor IIb 0.116
drl draculin 0.113
olig4 oligodendrocyte transcription factor 4 0.112
atoh1a atonal homolog 1a 0.111
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Dcr-2 Dicer-2 0.017
dco discs overgrown 0.013
Stat92E Signal-transducer and activator of transcription protein at 92E 0.012
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Homo sapiens
Name Description Probability Func Analog Organism
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.864
CREBBP CREB binding protein 0.863
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.799
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.766
EP300 E1A binding protein p300 0.747
JUN jun proto-oncogene 0.670
TAL1 T-cell acute lymphocytic leukemia 1 0.660
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.628
LAT linker for activation of T cells 0.556
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.536
SMAD7 SMAD family member 7 0.515
INSR insulin receptor 0.504
SYK spleen tyrosine kinase 0.449
JAG1 jagged 1 0.446
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.437
EGFR epidermal growth factor receptor 0.429
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.423
VEGFA vascular endothelial growth factor A 0.396
SOS1 son of sevenless homolog 1 (Drosophila) 0.394
RUNX1 runt-related transcription factor 1 0.394
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.361
MCL1 myeloid cell leukemia sequence 1 (BCL2-related) 0.355
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.349
HIPK2 homeodomain interacting protein kinase 2 0.296
HSPA1B heat shock 70kDa protein 1B 0.296
SMAD2 SMAD family member 2 0.291
SIRT1 sirtuin 1 0.233
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.226
FAS Fas (TNF receptor superfamily, member 6) 0.221
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.218
NRP1 neuropilin 1 0.211
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.205
ANXA1 annexin A1 0.197
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.195
RPLP1 ribosomal protein, large, P1 0.190
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.176
RPLP2 ribosomal protein, large, P2 0.165
SPTB spectrin, beta, erythrocytic 0.157
FN1 fibronectin 1 0.154
BMP2 bone morphogenetic protein 2 0.144
FASLG Fas ligand (TNF superfamily, member 6) 0.135
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.134
BID BH3 interacting domain death agonist 0.131
SMAD3 SMAD family member 3 0.131
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.128
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.123
BCL2L1 BCL2-like 1 0.122
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.122
PML promyelocytic leukemia 0.117
KLF4 Kruppel-like factor 4 (gut) 0.115
SKI v-ski sarcoma viral oncogene homolog (avian) 0.115
HOXB5 homeobox B5 0.114
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.113
CFLAR CASP8 and FADD-like apoptosis regulator 0.113
RPS11 ribosomal protein S11 0.112
XIAP X-linked inhibitor of apoptosis 0.111
SP1 Sp1 transcription factor 0.111
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 0.105
KLF6 Kruppel-like factor 6 0.104
GSK3B glycogen synthase kinase 3 beta 0.102
KAT2B K(lysine) acetyltransferase 2B 0.101
FKBP1A FK506 binding protein 1A, 12kDa 0.096
SLC4A1 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) 0.094
RPS15 ribosomal protein S15 0.093
MAF v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) 0.093
ANK1 ankyrin 1, erythrocytic 0.092
FGFR1 fibroblast growth factor receptor 1 0.091
STAT5A signal transducer and activator of transcription 5A 0.087
TXN thioredoxin 0.086
HBB hemoglobin, beta 0.084
MAPK8 mitogen-activated protein kinase 8 0.084
CDK2 cyclin-dependent kinase 2 0.082
FOS FBJ murine osteosarcoma viral oncogene homolog 0.081
TSC2 tuberous sclerosis 2 0.081
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.081
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.079
RPS12 ribosomal protein S12 0.079
RPS16 ribosomal protein S16 0.078
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.078
APAF1 apoptotic peptidase activating factor 1 0.078
LMO2 LIM domain only 2 (rhombotin-like 1) 0.077
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.077
RPS10 ribosomal protein S10 0.076
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.075
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.074
MAFB v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) 0.074
TKT transketolase 0.072
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.071
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.070
TGFB1 transforming growth factor, beta 1 0.070
DDIT3 DNA-damage-inducible transcript 3 0.070
ARID4B AT rich interactive domain 4B (RBP1-like) 0.069
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.068
NCOA6 nuclear receptor coactivator 6 0.067
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.066
DRD2 dopamine receptor D2 0.066
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.065
TCF12 transcription factor 12 0.065
HOXA10 homeobox A10 0.063
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.063
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Rattus norvegicus
Name Description Probability Func Analog Organism
Hba-a2 hemoglobin alpha, adult chain 2 0.708
LOC287167 globin, alpha 0.562
LOC100134871 beta globin minor gene 0.461
Alas2 aminolevulinate, delta-, synthase 2 0.325
Hbb hemoglobin, beta 0.180
LOC689064 beta-globin 0.160
Hbb-b1 hemoglobin, beta adult major chain 0.134
Laptm5 lysosomal protein transmembrane 5 0.113
Ptprc protein tyrosine phosphatase, receptor type, C 0.099
Cd247 Cd247 molecule 0.073
Tgfbr3 transforming growth factor, beta receptor III 0.059
Elk3 ELK3, ETS-domain protein 0.057
RT1-DMb RT1 class II, locus DMb 0.054
Flt1 FMS-related tyrosine kinase 1 0.054
Lcp2 lymphocyte cytosolic protein 2 0.046
Hck hemopoietic cell kinase 0.045
Pecam1 platelet/endothelial cell adhesion molecule 1 0.044
Lyz2 lysozyme 2 0.037
Cd4 Cd4 molecule 0.035
Lcp1 lymphocyte cytosolic protein 1 0.035
Tp53 tumor protein p53 0.028
Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 0.027
Cd44 Cd44 molecule 0.027
Marcks myristoylated alanine rich protein kinase C substrate 0.027
Il8rb interleukin 8 receptor, beta 0.024
Inpp5d inositol polyphosphate-5-phosphatase D 0.024
Casp3 caspase 3 0.024
Jak1 Janus kinase 1 0.024
Gja5 gap junction protein, alpha 5 0.023
Cd53 Cd53 molecule 0.022
Il1r1 interleukin 1 receptor, type I 0.020
Adam17 ADAM metallopeptidase domain 17 0.020
Cd37 CD37 molecule 0.020
Trim47 tripartite motif-containing 47 0.018
Rab5b RAB5B, member RAS oncogene family 0.017
Gna15 guanine nucleotide binding protein, alpha 15 0.017
Cxcr5 chemokine (C-X-C motif) receptor 5 0.017
Iqgap1 IQ motif containing GTPase activating protein 1 0.016
Vcan versican 0.016
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.016
RT1-DMa RT1 class II, locus DMa 0.016
Gucy2d guanylate cyclase 2d 0.016
Stk3 serine/threonine kinase 3 (STE20 homolog, yeast) 0.016
Axl Axl receptor tyrosine kinase 0.015
Tek TEK tyrosine kinase, endothelial 0.015
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.014
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.014
Bcl2 B-cell CLL/lymphoma 2 0.014
Smek2 SMEK homolog 2, suppressor of mek1 (Dictyostelium) 0.014
Fkbp4 FK506 binding protein 4 0.014
Igfbp5 insulin-like growth factor binding protein 5 0.014
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.013
Sox17 SRY (sex determining region Y)-box 17 0.012
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.012
Gzmk granzyme K 0.012
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.012
Ckm creatine kinase, muscle 0.012
Prdm2 PR domain containing 2, with ZNF domain 0.011
Ralbp1 ralA binding protein 1 0.011
Nos3 nitric oxide synthase 3, endothelial cell 0.011
Sh2b3 SH2B adaptor protein 3 0.011
Lat linker for activation of T cells 0.011
Prrx1 paired related homeobox 1 0.011
Kdr kinase insert domain receptor 0.011
Map4k1 mitogen activated protein kinase kinase kinase kinase 1 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism