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Homo sapiens

20 genes annotated in human

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regulation of embryonic development

GO:0045995

Any process that modulates the frequency, rate or extent of embryonic development.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of embryonic development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of embryonic development" (in gray)

Name	Description	Probability	Func Analog Organism
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.991	Mouse Worm
APC	adenomatous polyposis coli	0.958	Worm
RHOA	ras homolog gene family, member A	0.915	Fly
TP53	tumor protein p53	0.908
GSK3B	glycogen synthase kinase 3 beta	0.869
IGF1R	insulin-like growth factor 1 receptor	0.839	Human
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.734
CDT1	chromatin licensing and DNA replication factor 1	0.725
CSNK1E	casein kinase 1, epsilon	0.643
CTBP1	C-terminal binding protein 1	0.621
COL1A2	collagen, type I, alpha 2	0.589	Human
SNAP25	synaptosomal-associated protein, 25kDa	0.503
BMPR1A	bone morphogenetic protein receptor, type IA	0.478	Mouse
CDK2	cyclin-dependent kinase 2	0.471
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.458
COL1A1	collagen, type I, alpha 1	0.448	Human
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.448
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.445	Mouse
COL3A1	collagen, type III, alpha 1	0.441	Human
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.383
BMP2	bone morphogenetic protein 2	0.341	Zebrafish
OCLN	occludin	0.330
GBP3	guanylate binding protein 3	0.296
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.288
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.226
C1QC	complement component 1, q subcomponent, C chain	0.196	Human
STAG2	stromal antigen 2	0.196
LAT	linker for activation of T cells	0.182
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.179
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.177	Mouse Fly
SPTBN1	spectrin, beta, non-erythrocytic 1	0.176
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.175
EGFR	epidermal growth factor receptor	0.174
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.172
CREBBP	CREB binding protein	0.171
IL1R1	interleukin 1 receptor, type I	0.157
MAPK7	mitogen-activated protein kinase 7	0.152
LRP6	low density lipoprotein receptor-related protein 6	0.151	Mouse
SKP2	S-phase kinase-associated protein 2 (p45)	0.139
ITSN1	intersectin 1 (SH3 domain protein)	0.139
RYBP	RING1 and YY1 binding protein	0.130
C1QA	complement component 1, q subcomponent, A chain	0.118	Human
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.118
WNT3A	wingless-type MMTV integration site family, member 3A	0.118
JAG1	jagged 1	0.116
KLF4	Kruppel-like factor 4 (gut)	0.116
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.115
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.115
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.115
MEOX2	mesenchyme homeobox 2	0.112
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.111	Mouse Fly
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.108
CDKN3	cyclin-dependent kinase inhibitor 3	0.105
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.105
IL1RAP	interleukin 1 receptor accessory protein	0.093
AXIN1	axin 1	0.091
SETD7	SET domain containing (lysine methyltransferase) 7	0.091
CTTN	cortactin	0.085
COL4A1	collagen, type IV, alpha 1	0.084
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.082
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.082
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.082	Mouse Fly
SOCS3	suppressor of cytokine signaling 3	0.080
LRRK2	leucine-rich repeat kinase 2	0.079
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.074
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.073
NOTCH3	notch 3	0.073
JAK2	Janus kinase 2	0.073	Fly
DDR2	discoidin domain receptor tyrosine kinase 2	0.069
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.069	Worm
CCNB1	cyclin B1	0.069
SKP1	S-phase kinase-associated protein 1	0.068
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.067
CCNB2	cyclin B2	0.067
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.066
APOC1	apolipoprotein C-I	0.066
EIF4A3	eukaryotic translation initiation factor 4A3	0.065
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.064
ZYX	zyxin	0.063
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.063
HP	haptoglobin	0.062
ATXN1	ataxin 1	0.062
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.062
FLNA	filamin A, alpha	0.060
XIAP	X-linked inhibitor of apoptosis	0.056
HDAC1	histone deacetylase 1	0.055
KLF6	Kruppel-like factor 6	0.054	Human
MXRA5	matrix-remodelling associated 5	0.054
POSTN	periostin, osteoblast specific factor	0.053
FN1	fibronectin 1	0.053
WIPF1	WAS/WASL interacting protein family, member 1	0.052
CTBP2	C-terminal binding protein 2	0.052
FZD1	frizzled homolog 1 (Drosophila)	0.051	Human Mouse
COL5A1	collagen, type V, alpha 1	0.050
GLI1	GLI family zinc finger 1	0.050
YAP1	Yes-associated protein 1	0.050
RB1	retinoblastoma 1	0.049
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.048
DNM2	dynamin 2	0.048
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.047
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.046
COL5A2	collagen, type V, alpha 2	0.044
PXN	paxillin	0.044
ARHGAP1	Rho GTPase activating protein 1	0.044
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.044
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.044	Fly
IQGAP1	IQ motif containing GTPase activating protein 1	0.043
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.042
COL2A1	collagen, type II, alpha 1	0.042	Human
FOXA2	forkhead box A2	0.041	Mouse
KEAP1	kelch-like ECH-associated protein 1	0.041
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.040
GOLM1	golgi membrane protein 1	0.040
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.039
MCC	mutated in colorectal cancers	0.038
AKAP11	A kinase (PRKA) anchor protein 11	0.038
FGF18	fibroblast growth factor 18	0.038
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.037
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.037
FBXW11	F-box and WD repeat domain containing 11	0.037
CDK1	cyclin-dependent kinase 1	0.037
CTNNBIP1	catenin, beta interacting protein 1	0.035
FGF3	fibroblast growth factor 3	0.035
WNT5A	wingless-type MMTV integration site family, member 5A	0.035	Human Mouse
MEF2A	myocyte enhancer factor 2A	0.035
WDYHV1	WDYHV motif containing 1	0.033
FZD5	frizzled homolog 5 (Drosophila)	0.033	Human
FGF8	fibroblast growth factor 8 (androgen-induced)	0.033
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.033
DUSP1	dual specificity phosphatase 1	0.033
MDFI	MyoD family inhibitor	0.032
EPOR	erythropoietin receptor	0.032
ERBB2IP	erbb2 interacting protein	0.032
IHH	Indian hedgehog	0.032	Human
PROX1	prospero homeobox 1	0.032
PAX8	paired box 8	0.031
BBS10	Bardet-Biedl syndrome 10	0.030
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.030
TAF12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	0.030
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.029
KAT2A	K(lysine) acetyltransferase 2A	0.029
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.029	Mouse
AP2B1	adaptor-related protein complex 2, beta 1 subunit	0.028
HIC1	hypermethylated in cancer 1	0.028
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.028	Fly
MAP2K5	mitogen-activated protein kinase kinase 5	0.027	Rat
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.027
NCL	nucleolin	0.027
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.027
PSEN1	presenilin 1	0.026
JUN	jun proto-oncogene	0.026
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.026
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.026
GHR	growth hormone receptor	0.026
TBK1	TANK-binding kinase 1	0.026
ZNF217	zinc finger protein 217	0.025
SMAD1	SMAD family member 1	0.025
SFRP1	secreted frizzled-related protein 1	0.025	Mouse
SOX10	SRY (sex determining region Y)-box 10	0.025
HNF1A	HNF1 homeobox A	0.023
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.023
DST	dystonin	0.023
TWIST1	twist homolog 1 (Drosophila)	0.022
SREBF2	sterol regulatory element binding transcription factor 2	0.022
FBLN1	fibulin 1	0.022
AMOTL1	angiomotin like 1	0.022
ZFYVE9	zinc finger, FYVE domain containing 9	0.022
ASRGL1	asparaginase like 1	0.022
WEE1	WEE1 homolog (S. pombe)	0.021
ZRANB1	zinc finger, RAN-binding domain containing 1	0.021
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.021
COL6A1	collagen, type VI, alpha 1	0.021
HIST1H3B	histone cluster 1, H3b	0.020
WT1	Wilms tumor 1	0.020
A2M	alpha-2-macroglobulin	0.020
PHF3	PHD finger protein 3	0.020
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.020
DAXX	death-domain associated protein	0.020
HES2	hairy and enhancer of split 2 (Drosophila)	0.020
LBX1	ladybird homeobox 1	0.019
MYO9B	myosin IXB	0.019
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.019	Worm
NUP153	nucleoporin 153kDa	0.019
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.019
WNT1	wingless-type MMTV integration site family, member 1	0.019
CLSPN	claspin	0.018
LCAT	lecithin-cholesterol acyltransferase	0.018
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.018
NPAS1	neuronal PAS domain protein 1	0.018
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.018
OLFML2B	olfactomedin-like 2B	0.018
PLXDC1	plexin domain containing 1	0.018
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.018
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.018
TERT	telomerase reverse transcriptase	0.018
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.017
FZD8	frizzled homolog 8 (Drosophila)	0.017	Human
SOX9	SRY (sex determining region Y)-box 9	0.017
MAPK6	mitogen-activated protein kinase 6	0.017
MAP2K1	mitogen-activated protein kinase kinase 1	0.017
CCNE1	cyclin E1	0.017
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.017
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.017
GLIS2	GLIS family zinc finger 2	0.017
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.017
PDX1	pancreatic and duodenal homeobox 1	0.017
SOS1	son of sevenless homolog 1 (Drosophila)	0.017
BTRC	beta-transducin repeat containing	0.017
QKI	quaking homolog, KH domain RNA binding (mouse)	0.017
FGF2	fibroblast growth factor 2 (basic)	0.017
FOXF2	forkhead box F2	0.016
MAML1	mastermind-like 1 (Drosophila)	0.016
PBX1	pre-B-cell leukemia homeobox 1	0.016
TCF4	transcription factor 4	0.016
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.016
NCOA2	nuclear receptor coactivator 2	0.016
MSN	moesin	0.016
MPRIP	myosin phosphatase Rho interacting protein	0.016
ADAM12	ADAM metallopeptidase domain 12	0.016
RAX	retina and anterior neural fold homeobox	0.016
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.015
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.015
FGF4	fibroblast growth factor 4	0.015
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.015
GJA1	gap junction protein, alpha 1, 43kDa	0.015
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.015
WIF1	WNT inhibitory factor 1	0.015
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.015
CKS2	CDC28 protein kinase regulatory subunit 2	0.015	Worm
MAGOHB	mago-nashi homolog B (Drosophila)	0.015
KIF5B	kinesin family member 5B	0.015	Fly
FNDC1	fibronectin type III domain containing 1	0.015
TSC22D4	TSC22 domain family, member 4	0.014
SOCS1	suppressor of cytokine signaling 1	0.014
APOE	apolipoprotein E	0.014	Human
FOXD3	forkhead box D3	0.014
LHX1	LIM homeobox 1	0.014	Mouse
WNT7A	wingless-type MMTV integration site family, member 7A	0.014	Human
APOA1	apolipoprotein A-I	0.014
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.014
SFRP2	secreted frizzled-related protein 2	0.014	Mouse
DYNLL1	dynein, light chain, LC8-type 1	0.014
SFRP4	secreted frizzled-related protein 4	0.014	Human
ECEL1	endothelin converting enzyme-like 1	0.014
NDP	Norrie disease (pseudoglioma)	0.013
APOC3	apolipoprotein C-III	0.013
ONECUT1	one cut homeobox 1	0.013
PML	promyelocytic leukemia	0.013
LRRC17	leucine rich repeat containing 17	0.013
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.013
CCNE2	cyclin E2	0.013
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.013
FGF1	fibroblast growth factor 1 (acidic)	0.013
FOXL1	forkhead box L1	0.013
WNT6	wingless-type MMTV integration site family, member 6	0.013	Human
INSR	insulin receptor	0.013
ASPN	asporin	0.013
ZNRF1	zinc and ring finger 1	0.013
FOXO1	forkhead box O1	0.013
SIX2	SIX homeobox 2	0.013
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.012
NEUROD2	neurogenic differentiation 2	0.012
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.012
SPTBN4	spectrin, beta, non-erythrocytic 4	0.012
EFNA2	ephrin-A2	0.012
MYST2	MYST histone acetyltransferase 2	0.012
THY1	Thy-1 cell surface antigen	0.012
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.012
ORC1	origin recognition complex, subunit 1	0.012
NCK1	NCK adaptor protein 1	0.012
STAT5A	signal transducer and activator of transcription 5A	0.012
JAK3	Janus kinase 3	0.012	Fly
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.012
SSFA2	sperm specific antigen 2	0.012
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.012
CSNK1A1	casein kinase 1, alpha 1	0.012
SNX9	sorting nexin 9	0.012
SPAG9	sperm associated antigen 9	0.012
COL12A1	collagen, type XII, alpha 1	0.012
IRS2	insulin receptor substrate 2	0.012
COL10A1	collagen, type X, alpha 1	0.012
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.012	Fly
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.012
WWTR1	WW domain containing transcription regulator 1	0.012
CUL1	cullin 1	0.012
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.011	Mouse Fly
TLX2	T-cell leukemia homeobox 2	0.011
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.011
BMP4	bone morphogenetic protein 4	0.011	Zebrafish Mouse
MYOD1	myogenic differentiation 1	0.011
TAF6L	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa	0.011
FGFR3	fibroblast growth factor receptor 3	0.011
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.011
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.011
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.011
GJD3	gap junction protein, delta 3, 31.9kDa	0.011
NUP62	nucleoporin 62kDa	0.011
C19orf46	chromosome 19 open reading frame 46	0.011
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.011
LOX	lysyl oxidase	0.011
RBBP8	retinoblastoma binding protein 8	0.011
NSF	N-ethylmaleimide-sensitive factor	0.011
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.011
WISP1	WNT1 inducible signaling pathway protein 1	0.011
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.011	Worm
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.011
ACTN1	actinin, alpha 1	0.011
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.011
TLX1	T-cell leukemia homeobox 1	0.011
RHOB	ras homolog gene family, member B	0.011
WNT11	wingless-type MMTV integration site family, member 11	0.011	Human Fly
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.011
PEX26	peroxisomal biogenesis factor 26	0.011
NKX2-1	NK2 homeobox 1	0.010
LBP	lipopolysaccharide binding protein	0.010
SULF1	sulfatase 1	0.010	Zebrafish Mouse
TBP	TATA box binding protein	0.010
MNX1	motor neuron and pancreas homeobox 1	0.010
IER2	immediate early response 2	0.010
FAM83D	family with sequence similarity 83, member D	0.010
SSU72	SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae)	0.010
HIST1H1E	histone cluster 1, H1e	0.010
HNF4A	hepatocyte nuclear factor 4, alpha	0.010	Mouse
SCYL2	SCY1-like 2 (S. cerevisiae)	0.010
SDCBP	syndecan binding protein (syntenin)	0.010
NKX6-1	NK6 homeobox 1	0.010
C10orf116	chromosome 10 open reading frame 116	0.010
HOXD12	homeobox D12	0.010
MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	0.010
CDX2	caudal type homeobox 2	0.010