IMP

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Homo sapiens

27 genes annotated in human

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regulation of bmp signaling pathway

GO:0030510

Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of bmp signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of bmp signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
SMAD3	SMAD family member 3	1.000	Human
SMAD4	SMAD family member 4	0.996
FN1	fibronectin 1	0.991
FHL2	four and a half LIM domains 2	0.991
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.976	Fly
SMAD2	SMAD family member 2	0.975
SMAD1	SMAD family member 1	0.970	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.959	Human
SKIL	SKI-like oncogene	0.914	Human
SMAD7	SMAD family member 7	0.893
FBLN1	fibulin 1	0.870
JAG1	jagged 1	0.862
TGFBR1	transforming growth factor, beta receptor 1	0.622	Human Fly
TGFB1	transforming growth factor, beta 1	0.556
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.501
ENG	endoglin	0.501
SMAD5	SMAD family member 5	0.440	Human Zebrafish
BMP2	bone morphogenetic protein 2	0.411	Human
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.393
ZFYVE9	zinc finger, FYVE domain containing 9	0.392
LRP6	low density lipoprotein receptor-related protein 6	0.367
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.357	Human
AR	androgen receptor	0.286
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.257
FKBP1A	FK506 binding protein 1A, 12kDa	0.205
PXN	paxillin	0.192
NRP1	neuropilin 1	0.182
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.163
MFAP4	microfibrillar-associated protein 4	0.160
FSTL1	follistatin-like 1	0.139	Human Zebrafish
BMP1	bone morphogenetic protein 1	0.138
BCL2	B-cell CLL/lymphoma 2	0.137
ADAM12	ADAM metallopeptidase domain 12	0.136
SMAD6	SMAD family member 6	0.130
ACVR1	activin A receptor, type I	0.125	Human Fly
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.123
ELN	elastin	0.117
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.107
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.104
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.103
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.099	Fly
PIAS1	protein inhibitor of activated STAT, 1	0.097
FZD1	frizzled homolog 1 (Drosophila)	0.095	Mouse
NCOR2	nuclear receptor corepressor 2	0.094
VEGFA	vascular endothelial growth factor A	0.084
LIMD1	LIM domains containing 1	0.083
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.081	Zebrafish
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.080
MAPK8	mitogen-activated protein kinase 8	0.079
BMP4	bone morphogenetic protein 4	0.079	Human Mouse
ZEB2	zinc finger E-box binding homeobox 2	0.078
PTPRC	protein tyrosine phosphatase, receptor type, C	0.078
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.078	Human
EP300	E1A binding protein p300	0.076
CREBBP	CREB binding protein	0.075
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.074
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.074
WNT5A	wingless-type MMTV integration site family, member 5A	0.073	Human Mouse
CTGF	connective tissue growth factor	0.072	Human
LOX	lysyl oxidase	0.068
ATXN1	ataxin 1	0.068
ESR1	estrogen receptor 1	0.065
FGF18	fibroblast growth factor 18	0.064
FLNA	filamin A, alpha	0.064
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.062
MTMR4	myotubularin related protein 4	0.061
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.060
INHBA	inhibin, beta A	0.059
TIMP3	TIMP metallopeptidase inhibitor 3	0.054
PDGFC	platelet derived growth factor C	0.054
BMP7	bone morphogenetic protein 7	0.053
TGFB3	transforming growth factor, beta 3	0.052
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.052
COL1A1	collagen, type I, alpha 1	0.051
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.051
PARVA	parvin, alpha	0.050
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.050
SFRP1	secreted frizzled-related protein 1	0.050	Mouse
CXXC5	CXXC finger protein 5	0.048
TOX4	TOX high mobility group box family member 4	0.048
GDF5	growth differentiation factor 5	0.048
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.047
ITGB5	integrin, beta 5	0.047
SP1	Sp1 transcription factor	0.047
TP53	tumor protein p53	0.045
MAPK1	mitogen-activated protein kinase 1	0.044
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.043
F2R	coagulation factor II (thrombin) receptor	0.042
FST	follistatin	0.042	Human
WNT3A	wingless-type MMTV integration site family, member 3A	0.042	Human
ZMYND11	zinc finger, MYND-type containing 11	0.041	Zebrafish
NCOR1	nuclear receptor corepressor 1	0.041
CALD1	caldesmon 1	0.041
EGFR	epidermal growth factor receptor	0.041
COL1A2	collagen, type I, alpha 2	0.041
MAML1	mastermind-like 1 (Drosophila)	0.041
EFEMP1	EGF containing fibulin-like extracellular matrix protein 1	0.040
LTBP2	latent transforming growth factor beta binding protein 2	0.039
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.039
PRKG1	protein kinase, cGMP-dependent, type I	0.038
PTRF	polymerase I and transcript release factor	0.038
EPAS1	endothelial PAS domain protein 1	0.037
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.037
TBX5	T-box 5	0.036
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.036
DCAF7	DDB1 and CUL4 associated factor 7	0.036
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.036
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.035
GAS6	growth arrest-specific 6	0.034
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.034	Human
THBS1	thrombospondin 1	0.033
FBLN2	fibulin 2	0.032
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.032
SIRT1	sirtuin 1	0.032
ATN1	atrophin 1	0.032
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.032
SGSM2	small G protein signaling modulator 2	0.031
AXIN1	axin 1	0.031
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.031
YY1	YY1 transcription factor	0.031
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.031
GAS1	growth arrest-specific 1	0.030
RNF111	ring finger protein 111	0.030
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.030
COL6A1	collagen, type VI, alpha 1	0.030
HIC1	hypermethylated in cancer 1	0.030
SDC2	syndecan 2	0.029
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.029
FZD8	frizzled homolog 8 (Drosophila)	0.029
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.029
IGFBP5	insulin-like growth factor binding protein 5	0.029
THBS2	thrombospondin 2	0.029
TRIM33	tripartite motif containing 33	0.029
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.029
MSX1	msh homeobox 1	0.029	Mouse
PRRX1	paired related homeobox 1	0.029
RXRA	retinoid X receptor, alpha	0.028
FZD7	frizzled homolog 7 (Drosophila)	0.028
KAT2B	K(lysine) acetyltransferase 2B	0.028
TGFB2	transforming growth factor, beta 2	0.028
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.028
MSX2	msh homeobox 2	0.028	Mouse
AXL	AXL receptor tyrosine kinase	0.028
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.027
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.026	Human
ITGB4	integrin, beta 4	0.026
PRKCDBP	protein kinase C, delta binding protein	0.026
VEGFC	vascular endothelial growth factor C	0.026
CSNK1D	casein kinase 1, delta	0.026
FOXF2	forkhead box F2	0.026
TRAF4	TNF receptor-associated factor 4	0.026
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.026
MN1	meningioma (disrupted in balanced translocation) 1	0.025
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.025
WNT1	wingless-type MMTV integration site family, member 1	0.025
RUNX1	runt-related transcription factor 1	0.024
TCF4	transcription factor 4	0.024
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.024
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.024
SPRY2	sprouty homolog 2 (Drosophila)	0.024
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.023
RANBP9	RAN binding protein 9	0.023
PML	promyelocytic leukemia	0.023
RARA	retinoic acid receptor, alpha	0.023
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.023
TMEM47	transmembrane protein 47	0.023
F3	coagulation factor III (thromboplastin, tissue factor)	0.023
ATXN1L	ataxin 1-like	0.022
ATF2	activating transcription factor 2	0.022
IGFBP6	insulin-like growth factor binding protein 6	0.022
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.022
NRP2	neuropilin 2	0.021
COMP	cartilage oligomeric matrix protein	0.021
ARHGAP5	Rho GTPase activating protein 5	0.021
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	0.021
LUM	lumican	0.021
DLL1	delta-like 1 (Drosophila)	0.021
CXCL12	chemokine (C-X-C motif) ligand 12	0.021
CUL7	cullin 7	0.021
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.020
IGF2R	insulin-like growth factor 2 receptor	0.020
INHBB	inhibin, beta B	0.020
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.020
CPNE6	copine VI (neuronal)	0.020
HOXC8	homeobox C8	0.020
SFRP4	secreted frizzled-related protein 4	0.020
VCAN	versican	0.020
FBN2	fibrillin 2	0.020
CAV1	caveolin 1, caveolae protein, 22kDa	0.020
EPS8	epidermal growth factor receptor pathway substrate 8	0.019
RUNX2	runt-related transcription factor 2	0.019
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.019
COL6A2	collagen, type VI, alpha 2	0.019
FNDC3B	fibronectin type III domain containing 3B	0.019
ERBB2IP	erbb2 interacting protein	0.019
EPHA2	EPH receptor A2	0.019
SNW1	SNW domain containing 1	0.019
MAPK3	mitogen-activated protein kinase 3	0.019
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.018	Mouse
DOCK9	dedicator of cytokinesis 9	0.018
WNT4	wingless-type MMTV integration site family, member 4	0.018	Human
HOXA10	homeobox A10	0.018
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.018
SNIP1	Smad nuclear interacting protein 1	0.018
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.018
HOXA11	homeobox A11	0.018
CYR61	cysteine-rich, angiogenic inducer, 61	0.018
FOXF1	forkhead box F1	0.018
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.017
LIMK2	LIM domain kinase 2	0.017
DSE	dermatan sulfate epimerase	0.017
TCF12	transcription factor 12	0.017
FBLN5	fibulin 5	0.017
ACAN	aggrecan	0.017
ITIH5	inter-alpha (globulin) inhibitor H5	0.017
SOCS3	suppressor of cytokine signaling 3	0.017
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.017
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.016
IGF1	insulin-like growth factor 1 (somatomedin C)	0.016
LTBP4	latent transforming growth factor beta binding protein 4	0.016
PRRX2	paired related homeobox 2	0.016
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.016
SOCS5	suppressor of cytokine signaling 5	0.016
KCTD12	potassium channel tetramerisation domain containing 12	0.016
WNT2	wingless-type MMTV integration site family member 2	0.016	Human
HSPG2	heparan sulfate proteoglycan 2	0.016
SHB	Src homology 2 domain containing adaptor protein B	0.016
EDN1	endothelin 1	0.016
FAM46A	family with sequence similarity 46, member A	0.016
NCOA6	nuclear receptor coactivator 6	0.016
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.015
COL5A1	collagen, type V, alpha 1	0.015
SCARB2	scavenger receptor class B, member 2	0.015
GSK3B	glycogen synthase kinase 3 beta	0.015
GPR124	G protein-coupled receptor 124	0.015
IGFBP3	insulin-like growth factor binding protein 3	0.015	Zebrafish
TBX2	T-box 2	0.015
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.015
COL11A1	collagen, type XI, alpha 1	0.015
CAV2	caveolin 2	0.015	Human
FHL1	four and a half LIM domains 1	0.015
ANTXR2	anthrax toxin receptor 2	0.015
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.015
SORBS3	sorbin and SH3 domain containing 3	0.015
MAGEA2	melanoma antigen family A, 2	0.015
WIF1	WNT inhibitory factor 1	0.015
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.015
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.015
CLIP1	CAP-GLY domain containing linker protein 1	0.014
FERMT2	fermitin family member 2	0.014
NCOA1	nuclear receptor coactivator 1	0.014
TAL1	T-cell acute lymphocytic leukemia 1	0.014
SOX1	SRY (sex determining region Y)-box 1	0.014
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.014
C3orf64	chromosome 3 open reading frame 64	0.014
COL13A1	collagen, type XIII, alpha 1	0.014
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.014
MFAP5	microfibrillar associated protein 5	0.014
COL12A1	collagen, type XII, alpha 1	0.014
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.014
ADAM10	ADAM metallopeptidase domain 10	0.014
DLX5	distal-less homeobox 5	0.014
BIK	BCL2-interacting killer (apoptosis-inducing)	0.014
DUSP1	dual specificity phosphatase 1	0.014
PAM	peptidylglycine alpha-amidating monooxygenase	0.014
RBMS3	RNA binding motif, single stranded interacting protein 3	0.014
SELPLG	selectin P ligand	0.014
OSBPL8	oxysterol binding protein-like 8	0.013
EBF1	early B-cell factor 1	0.013
BIN1	bridging integrator 1	0.013
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.013
CLIC4	chloride intracellular channel 4	0.013
FHL3	four and a half LIM domains 3	0.013
SOX21	SRY (sex determining region Y)-box 21	0.013
CRLF1	cytokine receptor-like factor 1	0.013
RARB	retinoic acid receptor, beta	0.013
HAS2	hyaluronan synthase 2	0.013	Zebrafish
COL2A1	collagen, type II, alpha 1	0.012
TIMP2	TIMP metallopeptidase inhibitor 2	0.012
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.012
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.012	Mouse
RND3	Rho family GTPase 3	0.012
DUSP9	dual specificity phosphatase 9	0.012
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.012
CEP290	centrosomal protein 290kDa	0.012
ACACA	acetyl-CoA carboxylase alpha	0.012
LHFP	lipoma HMGIC fusion partner	0.012
SLIT2	slit homolog 2 (Drosophila)	0.012
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.012
DCN	decorin	0.012
NOTCH2NL	notch 2 N-terminal like	0.012
MAP2K4	mitogen-activated protein kinase kinase 4	0.012
DLC1	deleted in liver cancer 1	0.012
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.012
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.012
LBX1	ladybird homeobox 1	0.012
MFAP2	microfibrillar-associated protein 2	0.012
WNT10A	wingless-type MMTV integration site family, member 10A	0.012	Human
DOCK8	dedicator of cytokinesis 8	0.012
MYLK	myosin light chain kinase	0.012
IL11	interleukin 11	0.012
LIMS2	LIM and senescent cell antigen-like domains 2	0.011
WNT3	wingless-type MMTV integration site family, member 3	0.011	Human
SOD3	superoxide dismutase 3, extracellular	0.011
TMTC3	transmembrane and tetratricopeptide repeat containing 3	0.011
SOX9	SRY (sex determining region Y)-box 9	0.011
COL8A1	collagen, type VIII, alpha 1	0.011
PTHLH	parathyroid hormone-like hormone	0.011
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.011
PDLIM5	PDZ and LIM domain 5	0.011
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.011
TRIP6	thyroid hormone receptor interactor 6	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011
SNAI2	snail homolog 2 (Drosophila)	0.011
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.011
ALX4	ALX homeobox 4	0.011
TWIST1	twist homolog 1 (Drosophila)	0.011
GREM1	gremlin 1	0.011
PNPLA2	patatin-like phospholipase domain containing 2	0.011
PKN1	protein kinase N1	0.011
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.011
BGN	biglycan	0.011
NOV	nephroblastoma overexpressed gene	0.011	Human
JAG2	jagged 2	0.011
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.011
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.011
TFPI2	tissue factor pathway inhibitor 2	0.011
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.011
SOX7	SRY (sex determining region Y)-box 7	0.010
SHARPIN	SHANK-associated RH domain interactor	0.010
GDNF	glial cell derived neurotrophic factor	0.010
HEG1	HEG homolog 1 (zebrafish)	0.010
PTPRF	protein tyrosine phosphatase, receptor type, F	0.010
CD248	CD248 molecule, endosialin	0.010
LMOD1	leiomodin 1 (smooth muscle)	0.010
EHD2	EH-domain containing 2	0.010
FGF4	fibroblast growth factor 4	0.010
WT1	Wilms tumor 1	0.010
DLG5	discs, large homolog 5 (Drosophila)	0.010
PALLD	palladin, cytoskeletal associated protein	0.010
OBSL1	obscurin-like 1	0.010
GJA1	gap junction protein, alpha 1, 43kDa	0.010