IMP

Process View

Danio rerio

15 genes annotated in zebrafish

branching morphogenesis of an epithelial tube

The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "branching morphogenesis of an epithelial tube"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "branching morphogenesis of an epithelial tube" (in gray)

Name	Description	Probability	Func Analog Organism
shha	sonic hedgehog a	0.989	Mouse
notch3	notch homolog 3	0.964
pax2a	paired box gene 2a	0.869	Mouse
tbx1	T-box 1	0.866
jag1b	jagged 1b	0.855	Zebrafish
kdrl	kinase insert domain receptor like	0.812
dla	deltaA	0.712	Zebrafish
fbn2b	fibrillin 2b	0.626
wnt4a	wingless-type MMTV integration site family, member 4a	0.581	Mouse
jag2	jagged 2	0.567	Zebrafish
mecom	MDS1 and EVI1 complex locus	0.550
eya1	eyes absent homolog 1	0.534	Mouse
osr2	odd-skipped related 2 (Drosophila)	0.512
notch1a	notch homolog 1a	0.509	Mouse
ntn1a	netrin 1a	0.507
cdh2	cadherin 2, neuronal	0.503
boc	brother of CDO	0.488
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.466
myod1	myogenic differentiation 1	0.454
etv2	ets variant gene 2	0.444
pitx3	paired-like homeodomain transcription factor 3	0.439
bmp4	bone morphogenetic protein 4	0.424	Human Mouse Rat
dll4	delta-like 4 (Drosophila)	0.395
foxd3	forkhead box D3	0.395
hoxb8a	homeo box B8a	0.383
wnt10a	wingless-type MMTV integration site family, member 10a	0.381
bmp2a	bone morphogenetic protein 2a	0.350	Mouse
sox10	SRY-box containing gene 10	0.345
lmx1b.1	LIM homeobox transcription factor 1, beta 1	0.342
fgf10a	fibroblast growth factor 10a	0.340	Mouse
wnt11	wingless-type MMTV integration site family, member 11	0.314
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.313	Mouse
dld	deltaD	0.299	Zebrafish
plcg1	phospholipase C, gamma 1	0.292
hs6st1a	heparan sulfate 6-O-sulfotransferase 1a	0.291	Zebrafish
nrp1a	neuropilin 1a	0.284	Mouse
smo	smoothened homolog (Drosophila)	0.269	Mouse
hey2	hairy/enhancer-of-split related with YRPW motif 2	0.264
wnt3	wingless-type MMTV integration site family, member 3	0.263
grem2	gremlin 2, cysteine knot superfamily	0.263
six4b	sine oculis homeobox homolog 4b	0.262	Mouse
traf4a	tnf receptor-associated factor 4a	0.232
chd	chordin	0.226
ptgs1	prostaglandin-endoperoxide synthase 1	0.219
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.218	Mouse
hs6st2	heparan sulfate 6-O-sulfotransferase 2	0.217
frem3	Fras1 related extracellular matrix 3	0.212
wnt5b	wingless-type MMTV integration site family, member 5b	0.199	Mouse
igfbp3	insulin-like growth factor binding protein 3	0.199
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.198
nkx3.2	NK3 homeobox 2	0.189
myog	myogenin	0.188
tll1	tolloid-like 1	0.181
wt1b	wilms tumor 1b	0.181	Human Mouse
foxa2	forkhead box A2	0.173	Mouse
foxi1	forkhead box I1	0.169
hoxb2a	homeo box B2a	0.162
fsta	follistatin a	0.160
wt1a	wilms tumor 1a	0.159	Human Mouse
msxb	muscle segment homeobox B	0.156
celsr1a	cadherin EGF LAG seven-pass G-type receptor 1a	0.155	Mouse
hoxd4a	homeo box D4a	0.154
slit3	slit (Drosophila) homolog 3	0.152
lamb1a	laminin, beta 1a	0.138
gli1	GLI-Kruppel family member 1	0.137
si:ch73-60e21.1	si:ch73-60e21.1	0.136
wnt3a	wingless-type MMTV integration site family, member 3A	0.136
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.128
sema3ab	semaphorin 3ab	0.122
hoxb5b	homeo box B5b	0.121
eng1a	engrailed 1a	0.119
lamc1	laminin, gamma 1	0.118
hoxc6a	homeo box C6a	0.117
pou3f3a	POU class 3 homeobox 3a	0.116
fgf3	fibroblast growth factor 3	0.113
edn1	endothelin 1	0.113
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.108
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.108	Mouse
tp53	tumor protein p53	0.106
sulf1	sulfatase 1	0.106
pea3	ETS-domain transcription factor pea3	0.105	Mouse
pax5	paired box gene 5	0.103
hoxa2b	homeo box A2b	0.101
brd2a	bromodomain-containing 2a	0.098
wu:fv91b12	wu:fv91b12	0.098
cxcl12b	chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)	0.097	Mouse
hapln3	hyaluronan and proteoglycan link protein 3	0.096
unc45a	unc-45 homolog A (C. elegans)	0.093
LOC100000687	signal peptide, CUB and EGF-like domain-containing protein 3-like	0.093
sema3aa	semaphorin 3aa	0.093	Zebrafish
wnt9b	wingless-type MMTV integration site family, member 9B	0.091	Mouse
disc1	disrupted in schizophrenia 1	0.091
bmp2b	bone morphogenetic protein 2b	0.089	Mouse
efnb2a	ephrin B2a	0.087
mmp2	matrix metalloproteinase 2	0.086
barx1	BarH-like homeobox 1	0.086
sars	seryl-tRNA synthetase	0.085
cnnm2a	cyclin M2a	0.083
aldh1a2	aldehyde dehydrogenase 1 family, member A2	0.081
nkx2.3	NK2 transcription factor related 3	0.081
sox2	SRY-box containing gene 2	0.081	Mouse
wnt1	wingless-type MMTV integration site family, member 1	0.079	Mouse Fly
mib	mind bomb	0.079
hmx1	H6 homeo box 1	0.078
nrarpa	notch-regulated ankyrin repeat protein a	0.078
hoxc9a	homeo box C9a	0.077
fibin	fin bud initiation factor	0.073
mab21l2	mab-21-like 2	0.072
hs3st3b1b	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b	0.071
mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.071
hnf1ba	HNF1 homeobox Ba	0.068	Mouse
myf5	myogenic factor 5	0.067
im:7156396	im:7156396	0.066
vegfaa	vascular endothelial growth factor Aa	0.066
twist1a	twist1a	0.065
lef1	lymphocyte enhancer binding factor 1	0.064	Mouse
hoxc4a	homeo box C4a	0.064
flncb	filamin C, gamma b (actin binding protein 280)	0.063
hoxa13b	homeo box A13b	0.062
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.061
epb4.1l4	erythrocyte protein band 4.1-like 4	0.061
flh	floating head	0.060
foxj1b	forkhead box J1b	0.060
dlc	deltaC	0.060	Zebrafish
hoxc1a	homeo box C1a	0.059
gli2a	GLI-Kruppel family member GLI2a	0.059	Mouse
hhip	hedgehog interacting protein	0.059	Mouse
gja3	gap junction protein, alpha 3	0.057
hoxb3a	homeo box B3a	0.056
twist1b	twist1b	0.056
pou3f3b	POU class 3 homeobox 3b	0.056
hoxd12a	homeo box D12a	0.055
bmp1a	bone morphogenetic protein 1a	0.055
hoxd3a	homeo box D3a	0.054
fras1	Fraser syndrome 1	0.054
fgf24	fibroblast growth factor 24	0.052
stac3	SH3 and cysteine rich domain 3	0.052
plxnd1	plexin D1	0.051
nkx2.1a	NK2 homeobox 1a	0.051
tbx16	T-box gene 16	0.049
rspo1	R-spondin homolog (Xenopus laevis)	0.049
onecutl	one cut domain, family member, like	0.048
met	met proto-oncogene (hepatocyte growth factor receptor)	0.048
zgc:111821	zgc:111821	0.046
sfrp1a	secreted frizzled-related protein 1a	0.046
spry1	sprouty homolog 1 (Drosophila)	0.046
wnt2	wingless-type MMTV integration site family member 2	0.046	Mouse
tbx15	T-box 15	0.045
fn1	fibronectin 1	0.045
neurod4	neurogenic differentiation 4	0.045
atoh7	atonal homolog 7	0.044
sim2	single-minded homolog 2 (Drosophila)	0.044
plce1	phospholipase C, epsilon 1	0.043
ahi1	Abelson helper integration site 1	0.042
pcdh8	protocadherin 8	0.040
nfatc1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.040
nkx2.5	NK2 transcription factor related 5	0.040
gpr126	G protein-coupled receptor 126	0.040
mpx	myeloid-specific peroxidase	0.040
hapln1a	hyaluronan and proteoglycan link protein 1a	0.039
prrx1b	paired related homeobox 1b	0.039
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.039
skia	nuclear oncoprotein skia	0.039
hoxd10a	homeo box D10a	0.039
ilk	integrin linked kinase	0.039	Mouse
scube2	signal peptide, CUB domain, EGF-like 2	0.038
atoh8	atonal homolog 8	0.038
ctsc	cathepsin C	0.038
tm9sf2	transmembrane 9 superfamily member 2	0.037
fgf8b	fibroblast growth factor 8 b	0.037	Mouse
gch2	GTP cyclohydrolase 2	0.037
sim1a	single-minded homolog 1a (Drosophila)	0.036
arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.035
wnt8b	wingless-type MMTV integration site family, member 8b	0.035
she	Src homology 2 domain containing E	0.035
her3	hairy-related 3	0.035
sox1a	SRY-box containing gene 1a	0.034
acvrl1	activin A receptor type II-like 1	0.034
sox21a	SRY-box containing gene 21a	0.034
tnnt3a	troponin T3a, skeletal, fast	0.034	Zebrafish
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.033	Mouse
evx2	even-skipped homeobox 2	0.033
acp5b	acid phosphatase 5b, tartrate resistant	0.033
acvr1l	activin A receptor, type I like	0.033
angpt1	angiopoietin 1	0.033
efna5b	ephrin A5b	0.032
hs3st3b1a	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1a	0.032
bon	bonnie and clyde	0.032
tfec	transcription factor EC	0.032
nr2f5	nuclear receptor subfamily 2, group F, member 5	0.032
emx3	empty spiracles homeobox 3	0.031
runx2a	runt-related transcription factor 2a	0.031
notch1b	notch homolog 1b	0.031	Mouse
dusp6	dual specificity phosphatase 6	0.031	Fly
vhl	von Hippel-Lindau tumor suppressor	0.031
runx1	runt-related transcription factor 1	0.031
dlx5a	distal-less homeobox gene 5a	0.031
tnnt2a	troponin T2a, cardiac	0.030
cx43.4	connexin 43.4	0.030
nrp2a	neuropilin 2a	0.029
limk2	LIM domain kinase 2	0.029
foxp2	forkhead box P2	0.029
flrt3	fibronectin leucine rich transmembrane 3	0.029
pnrc2	proline-rich nuclear receptor coactivator 2	0.028
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.028
vdra	vitamin D receptor a	0.028
pax8	paired box gene 8	0.028	Human Mouse
nrg2a	neuregulin 2a	0.028
irx3b	iroquois homeobox protein 3b	0.028
wls	wntless homolog (Drosophila)	0.027
grhl2a	grainyhead-like 2a (Drosophila)	0.027
pdgfaa	platelet-derived growth factor alpha a	0.027
hdac4	histone deacetylase 4	0.027
irx1a	iroquois homeobox protein 1, a	0.026
fgfrl1b	fibroblast growth factor receptor-like 1b	0.026
gyltl1b	glycosyltransferase-like 1b	0.026
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.026
robo2	roundabout homolog 2	0.026
dlx2a	distal-less homeobox gene 2a	0.026
gdf6a	growth differentiation factor 6a	0.026
dmbx1a	diencephalon/mesencephalon homeobox 1a	0.026
spon2a	spondin 2a, extracellular matrix protein	0.026
tpm4	tropomyosin 4	0.026
pax2b	paired box gene 2b	0.026	Human Mouse
foxj1a	forkhead box J1a	0.026
dopey1	dopey family member 1	0.025
tmem2	transmembrane protein 2	0.025
ascl1a	achaete-scute complex-like 1a (Drosophila)	0.025
hoxa9b	homeo box A9b	0.025
fli1a	friend leukemia integration 1a	0.024
ntn2	netrin 2	0.024
sox9a	SRY-box containing gene 9a	0.024	Mouse
col15a1b	collagen, type XV, alpha 1b	0.024
lama1	laminin, alpha 1	0.024
ism1	isthmin 1	0.024
ttna	titin a	0.024
pkd2	polycystic kidney disease 2	0.024	Human
sema3fa	semaphorin 3fa	0.024
zgc:101724	zgc:101724	0.023
igf1rb	insulin-like growth factor 1b receptor	0.023
gdnf	glial cell derived neurotrophic factor	0.023	Human Mouse Rat
nphs1l	nephrosis 1, congenital, Finnish type (nephrin)-like	0.023
hs3st1l1	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like1	0.022
fev	FEV (ETS oncogene family)	0.022
hoxa11a	homeo box A11a	0.022
smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.022
col8a1a	collagen, type VIII, alpha 1a	0.022
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.022	Mouse
smyhc1l	slow myosin heavy chain 1, like	0.022
neurog1	neurogenin 1	0.021
lhx1b	LIM homeobox 1b	0.021	Mouse
fgf20b	fibroblast growth factor 20b	0.021
hoxa9a	homeo box A9a	0.021
dbx1a	developing brain homeobox 1a	0.021
ren	renin	0.020
barx2	BarH-like homeobox 2	0.020
LOC100332039	ectonucleotide pyrophosphatase/phosphodiesterase family member 2-like	0.020
pax3b	paired box gene 3b	0.020
ldb2a	LIM-domain binding factor 2a	0.020
gpc4	glypican 4	0.020
ccm2	cerebral cavernous malformation 2	0.020
rtcd1	RNA terminal phosphate cyclase domain 1	0.020
hlx1	H2.0-like homeo box 1 (Drosophila)	0.019
ncs1a	neuronal calcium sensor 1a	0.019
tnfsf10l	tumor necrosis factor (ligand) superfamily, member 10 like	0.019
vangl2	vang-like 2 (van gogh, Drosophila)	0.019
csgalnact2	chondroitin sulfate N-acetylgalactosaminyltransferase 2	0.019
vsx2	visual system homeobox 2	0.019
cdx4	caudal type homeo box transcription factor 4	0.019
lnx2b	ligand of numb-protein X 2b	0.018
fgf8a	fibroblast growth factor 8 a	0.018	Mouse
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.018
cyp24a1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.018
frem1a	Fras1 related extracellular matrix 1a	0.018
tcf21	transcription factor 21	0.018	Mouse
aplnrb	apelin receptor b	0.018
fstl1a	follistatin-like 1a	0.018
tpbgl	trophoblast glycoprotein-like	0.018
kal1b	Kallmann syndrome 1b sequence	0.017
twist3	twist3	0.017
hoxb5a	homeo box B5a	0.017
sall4	sal-like 4 (Drosophila)	0.017
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.017
ccbe1	collagen and calcium binding EGF domains 1	0.017
ntn1b	netrin 1b	0.017	Zebrafish
her9	hairy-related 9	0.017
nkx2.2a	NK2 transcription factor related 2a	0.017
rorb	RAR-related orphan receptor B	0.017
her5	hairy-related 5	0.017
ndr2	nodal-related 2	0.017
brd2b	bromodomain containing 2b	0.016
antxr1	anthrax toxin receptor 1	0.016
fzd7b	frizzled homolog 7b	0.016
tbx5a	T-box 5a	0.016
wtip	Wilms tumor 1 interacting protein	0.016
birc2	baculoviral IAP repeat-containing 2	0.016
hhex	hematopoietically expressed homeobox	0.016
jam2b	junctional adhesion molecule 2b	0.016
dzip1	DAZ interacting protein 1	0.016
alcamb	activated leukocyte cell adhesion molecule b	0.016
tie2	endothelium-specific receptor tyrosine kinase 2	0.016
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.015
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.015
efna2	ephrin A2	0.015
dkk1b	dickkopf 1b	0.015
pax7a	paired box gene 7a	0.015
pax6b	paired box gene 6b	0.015
wnt2ba	wingless-type MMTV integration site family, member 2Ba	0.015	Mouse
foxc1b	forkhead box C1b	0.014
robo1	roundabout homolog 1	0.014
unc5b	unc-5 homolog B (C. elegans)	0.014
ptch2	patched 2	0.014
esama	endothelial cell adhesion molecule a	0.014
si:ch1073-210b3.1	si:ch1073-210b3.1	0.014
calcrla	calcitonin receptor-like a	0.014
zgc:101606	zgc:101606	0.014
eng2b	engrailed 2b	0.014
itga3b	integrin, alpha 3b	0.014
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.014
nr2f6a	nuclear receptor subfamily 2, group F, member 6a	0.014
chd7	chromodomain helicase DNA binding protein 7	0.014
spaw	southpaw	0.014
runx3	runt-related transcription factor 3	0.014
wnt11r	wingless-type MMTV integration site family, member 11, related	0.014
ubiad1	UbiA prenyltransferase domain containing 1	0.013
csnk1da	casein kinase 1, delta a	0.013
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.013
syne2b	spectrin repeat containing, nuclear envelope 2b	0.013
nppa	natriuretic peptide precursor A	0.013
hoxb10a	homeo box B10a	0.013
csnk1a1	casein kinase 1, alpha 1	0.013
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.013
spsb4a	splA/ryanodine receptor domain and SOCS box containing 4a	0.013
ifnphi1	interferon phi 1	0.013
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.013
stat5.1	signal transducer and activator of transcription 5.1	0.013
foxg1a	forkhead box G1a	0.013
mpp6b	membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)	0.013
smad3a	MAD homolog 3a (Drosophila)	0.013
shmt2	serine hydroxymethyltransferase 2 (mitochondrial)	0.012
emilin1a	elastin microfibril interfacer 1a	0.012
fgfr4	fibroblast growth factor receptor 4	0.012	Fly
vsg1	vessel-specific 1	0.012
mcamb	melanoma cell adhesion molecule b	0.012
msxa	muscle segment homeobox A	0.012	Mouse
si:dkey-261h17.1	si:dkey-261h17.1	0.012
fgf19	fibroblast growth factor 19	0.012
hug	HuG	0.012
dopey2	dopey family member 2	0.012
LOC100000500	sclerostin-like	0.012
lims1	LIM and senescent cell antigen-like domains 1	0.012
tbx22	T-box 22	0.012
pth2r	parathyroid hormone 2 receptor	0.012
efna3b	ephrin A3b	0.012
fzd9b	frizzled homolog 9b	0.012
eya4	eyes absent homolog 4 (Drosophila)	0.012
spint1a	serine peptidase inhibitor, Kunitz type 1 a	0.012
ednra	endothelin receptor type A	0.012	Mouse
frem2a	Fras1 related extracellular matrix protein 2a	0.012
cart1	cartilage paired-class homeoprotein 1	0.012
hoxb6b	homeo box B6b	0.011
oc90	otoconin 90	0.011
gata4	GATA-binding protein 4	0.011
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.011	Fly
hmx3	homeo box (H6 family) 3	0.011
lhx3	LIM homeobox 3	0.011
dkk3	dickkopf homolog 3 (Xenopus laevis)	0.011
slmo2	slowmo homolog 2 (Drosophila)	0.011
zgc:92715	zgc:92715	0.011
tnnc1b	troponin C type 1b (slow)	0.011
zgc:110010	zgc:110010	0.011
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.011
col4a5	collagen, type IV, alpha 5 (Alport syndrome)	0.011
mobkl2a	MOB1, Mps One Binder kinase activator-like 2A (yeast)	0.011
polr2a	polymerase (RNA) II (DNA directed) polypeptide A	0.011
nkx2.7	NK2 transcription factor related 7	0.011
zgc:86759	zgc:86759	0.010
mafl	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L	0.010
chrna4	cholinergic receptor, nicotinic, alpha 4	0.010
yap1	Yes-associated protein 1	0.010
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.010
clstn2	calsyntenin 2	0.010
npnt	nephronectin	0.010
bcl2	B-cell leukemia/lymphoma 2	0.010	Mouse
hmx2	H6 family homeobox 2	0.010
foxc1a	forkhead box C1a	0.010
rerea	arginine-glutamic acid dipeptide (RE) repeats a	0.010
srf	serum response factor	0.010	Mouse Fly