The network for 'determination of dorsal ventral asymmetry' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

determination of dorsal ventral asymmetry

Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.

Homo sapiens
Name Description Probability Func Analog Organism
BMPR1A bone morphogenetic protein receptor, type IA 0.992
TGFB1 transforming growth factor, beta 1 0.950
FSTL1 follistatin-like 1 0.948
HDAC2 histone deacetylase 2 0.941
SMAD7 SMAD family member 7 0.903
BMP2 bone morphogenetic protein 2 0.888
FKBP1A FK506 binding protein 1A, 12kDa 0.810
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.563
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.437
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.429
CHRD chordin 0.423
TGFB3 transforming growth factor, beta 3 0.384
BMP1 bone morphogenetic protein 1 0.366
ENG endoglin 0.343
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.315
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma 0.279
ATF3 activating transcription factor 3 0.266
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.232
GDF5 growth differentiation factor 5 0.230
SMAD3 SMAD family member 3 0.230
ZFYVE9 zinc finger, FYVE domain containing 9 0.215
MAPK9 mitogen-activated protein kinase 9 0.199
SMAD2 SMAD family member 2 0.185
HDAC3 histone deacetylase 3 0.177
DBP D site of albumin promoter (albumin D-box) binding protein 0.169
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 0.152
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.142
ATF2 activating transcription factor 2 0.138
NOG noggin 0.133
NRP1 neuropilin 1 0.122
PSEN1 presenilin 1 0.120
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.111
SMAD1 SMAD family member 1 0.107
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.101
SNIP1 Smad nuclear interacting protein 1 0.084
BMP4 bone morphogenetic protein 4 0.065
TGFBR1 transforming growth factor, beta receptor 1 0.065
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.055
BTRC beta-transducin repeat containing 0.054
MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.051
MAPK14 mitogen-activated protein kinase 14 0.050
PPIL4 peptidylprolyl isomerase (cyclophilin)-like 4 0.048
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.047
MAP2K7 mitogen-activated protein kinase kinase 7 0.044
INHBA inhibin, beta A 0.044
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.043
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.043
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.043
SP1 Sp1 transcription factor 0.043
PELI2 pellino homolog 2 (Drosophila) 0.042
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.041
APC adenomatous polyposis coli 0.040
SMAD4 SMAD family member 4 0.040
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.038
GLIS2 GLIS family zinc finger 2 0.037
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.036
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.035
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.035
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.034
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.034
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.034
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 0.033
BIN1 bridging integrator 1 0.033
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.032
ZMYND11 zinc finger, MYND-type containing 11 0.032
SMAD6 SMAD family member 6 0.031
PPP4R2 protein phosphatase 4, regulatory subunit 2 0.031
AXIN1 axin 1 0.028
BMPR1B bone morphogenetic protein receptor, type IB 0.027
JUN jun proto-oncogene 0.027
UHRF2 ubiquitin-like with PHD and ring finger domains 2 0.026
FBXW11 F-box and WD repeat domain containing 11 0.026
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.026
MTA3 metastasis associated 1 family, member 3 0.025
GATAD2A GATA zinc finger domain containing 2A 0.025
GATAD2B GATA zinc finger domain containing 2B 0.025
LTBP4 latent transforming growth factor beta binding protein 4 0.024
TRIB3 tribbles homolog 3 (Drosophila) 0.024
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.024
YY1 YY1 transcription factor 0.024
FERMT2 fermitin family member 2 0.023
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.023
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.022
HRG histidine-rich glycoprotein 0.022
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.021
NCOA6 nuclear receptor coactivator 6 0.021
DUSP4 dual specificity phosphatase 4 0.021
MYD88 myeloid differentiation primary response gene (88) 0.021
COL2A1 collagen, type II, alpha 1 0.021
JUP junction plakoglobin 0.020
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.020
CHD4 chromodomain helicase DNA binding protein 4 0.020
ATN1 atrophin 1 0.020
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.020
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.020
IGFBP6 insulin-like growth factor binding protein 6 0.020
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.019
VEGFA vascular endothelial growth factor A 0.019
ACVR1 activin A receptor, type I 0.019
FBXW8 F-box and WD repeat domain containing 8 0.019
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
bmp4 bone morphogenetic protein 4 1.000
chd chordin 0.973
flh floating head 0.954
wnt10a wingless-type MMTV integration site family, member 10a 0.947
tbx16 T-box gene 16 0.928
fgf3 fibroblast growth factor 3 0.924
bmp2b bone morphogenetic protein 2b 0.911
tbx2b T-box 2b 0.880
dkk1b dickkopf 1b 0.846
wnt11r wingless-type MMTV integration site family, member 11, related 0.807
dharma dharma 0.807
ndr2 nodal-related 2 0.791
wnt9b wingless-type MMTV integration site family, member 9B 0.768
vent ventral expressed homeobox 0.748
tll1 tolloid-like 1 0.705
hand2 heart and neural crest derivatives expressed transcript 2 0.678
gbx2 gastrulation brain homeo box 2 0.677
lft1 lefty1 0.666
fras1 Fraser syndrome 1 0.653
msxb muscle segment homeobox B 0.646
map2k4a mitogen-activated protein kinase kinase 4a 0.632
og9x OG9 homeobox gene 0.627
bmpr2b bone morphogenetic protein receptor, type II b (serine/threonine kinase) 0.624
tfap2a transcription factor AP-2 alpha 0.581
tbx2a T-box gene 2a 0.580
admp anti-dorsalizing morphogenic protein 0.563
tbx1 T-box 1 0.562
fgf8a fibroblast growth factor 8 a 0.562
lft2 lefty2 0.562
ntla no tail a 0.543
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.541
pcdh8 protocadherin 8 0.520
bmp2a bone morphogenetic protein 2a 0.519
frem3 Fras1 related extracellular matrix 3 0.488
sox32 SRY-box containing gene 32 0.483
bmp7a bone morphogenetic protein 7a 0.473
twist3 twist3 0.427
wnt1 wingless-type MMTV integration site family, member 1 0.425
msxd muscle segment homeobox D 0.412
dlx5a distal-less homeobox gene 5a 0.391
shha sonic hedgehog a 0.391
oep one-eyed pinhead 0.389
fn1 fibronectin 1 0.374
frem2a Fras1 related extracellular matrix protein 2a 0.366
dlx3b distal-less homeobox gene 3b 0.357
wnt5b wingless-type MMTV integration site family, member 5b 0.339
foxd5 forkhead box D5 0.339
fgf17 fibroblast growth factor 17 0.328
eve1 even-skipped-like1 0.327
wnt7aa wingless-type MMTV integration site family, member 7Aa 0.313
LOC100000687 signal peptide, CUB and EGF-like domain-containing protein 3-like 0.304
lama5 laminin, alpha 5 0.302
tp63 tumor protein p63 0.299
lef1 lymphocyte enhancer binding factor 1 0.290
fzd10 frizzled homolog 10 0.286
itga3b integrin, alpha 3b 0.284
wnt7ba wingless-type MMTV integration site family, member 7Ba 0.280
dhrs3a dehydrogenase/reductase (SDR family) member 3a 0.275
hmx4 H6 family homeobox 4 0.269
wnt11 wingless-type MMTV integration site family, member 11 0.263
fbln1 fibulin 1 0.262
dlx2a distal-less homeobox gene 2a 0.254
wnt8a wingless-type MMTV integration site family, member 8a 0.244
wnt4a wingless-type MMTV integration site family, member 4a 0.238
pnx posterior neuron-specific homeobox 0.235
hmx1 H6 homeo box 1 0.226
smad9 MAD homolog 9 (Drosophila) 0.224
hapln3 hyaluronan and proteoglycan link protein 3 0.220
si:dkeyp-50f5.1 si:dkeyp-50f5.1 0.215
wnt5a wingless-type MMTV integration site family, member 5a 0.211
vox ventral homeobox 0.210
frem1a Fras1 related extracellular matrix 1a 0.209
fbn2b fibrillin 2b 0.208
spns2 spinster homolog 2 (Drosophila) 0.208
wnt10b wingless-type MMTV integration site family, member 10b 0.202
ccm2 cerebral cavernous malformation 2 0.201
eomesa eomesodermin homolog a 0.197
zfyve26 zinc finger, FYVE domain containing 26 0.193
szl sizzled 0.186
hoxa13b homeo box A13b 0.183
gli1 GLI-Kruppel family member 1 0.180
isl2a islet2a 0.179
klf4 Kruppel-like factor 4 0.179
brd4 bromodomain containing 4 0.172
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.171
ved ventrally expressed dharma/bozozok antagonist 0.170
msxe muscle segment homeobox E 0.165
msxc muscle segment homeobox C 0.162
dlx4a distal-less homeobox gene 4a 0.157
map2k4b mitogen-activated protein kinase kinase 4b 0.153
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.151
bmpr2a bone morphogenetic protein receptor, type II a (serine/threonine kinase) 0.151
rxrbb retinoid x receptor, beta b 0.150
mab21l2 mab-21-like 2 0.147
gsc goosecoid 0.142
acvr1b activin A receptor, type IB 0.139
myf5 myogenic factor 5 0.135
mespa mesoderm posterior a 0.130
mapk4 mitogen-activated protein kinase 4 0.124
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.123
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Drosophila melanogaster
Name Description Probability Func Analog Organism
en engrailed 0.739
hh hedgehog 0.657
dpp decapentaplegic 0.580
gbb glass bottom boat 0.474
cv-c crossveinless c 0.467
Tl Toll 0.441
Med Medea 0.392
sog short gastrulation 0.344
Ras85D Ras oncogene at 85D 0.316
ems empty spiracles 0.279
fra frazzled 0.271
Egfr Epidermal growth factor receptor 0.266
baz bazooka 0.263
tld tolloid 0.250
tutl turtle 0.184
comm commissureless 0.180
Dad Daughters against dpp 0.175
ci cubitus interruptus 0.171
put punt 0.171
Mad Mothers against dpp 0.166
tum tumbleweed 0.161
Akt1 CG4006 gene product from transcript CG4006-RA 0.155
cact cactus 0.136
kn knot 0.133
shn schnurri 0.132
wg wingless 0.127
eya eyes absent 0.126
smo smoothened 0.124
tup tailup 0.119
Arf79F ADP ribosylation factor 79F 0.119
ash2 absent, small, or homeotic discs 2 0.115
if inflated 0.110
lea leak 0.101
stumps CG31317 gene product from transcript CG31317-RC 0.095
beta-Spec beta Spectrin 0.091
Su(z)12 CG8013 gene product from transcript CG8013-RA 0.089
dve defective proventriculus 0.088
Bx42 CG8264 gene product from transcript CG8264-RA 0.086
kay kayak 0.085
kni knirps 0.082
robo roundabout 0.077
vvl ventral veins lacking 0.077
hth homothorax 0.075
ecd ecdysoneless 0.069
ptc patched 0.065
Adf1 Adh transcription factor 1 0.064
Kr-h1 Kruppel homolog 1 0.063
sax saxophone 0.061
Nrg Neuroglian 0.053
por porcupine 0.053
ea easter 0.052
lwr lesswright 0.051
sli slit 0.049
brk brinker 0.049
spi spitz 0.048
tok tolkin 0.048
rho rhomboid 0.047
salm spalt major 0.044
Trim9 CG31721 gene product from transcript CG31721-RB 0.042
Doa Darkener of apricot 0.042
gsb gooseberry 0.041
acj6 abnormal chemosensory jump 6 0.041
shrb shrub 0.040
tsg twisted gastrulation 0.040
drl derailed 0.039
MRG15 CG6363 gene product from transcript CG6363-RA 0.038
His2Av Histone H2A variant 0.038
robo3 CG5423 gene product from transcript CG5423-RA 0.038
grn grain 0.038
trio CG18214 gene product from transcript CG18214-RA 0.037
fj four-jointed 0.036
dia diaphanous 0.036
cv-2 crossveinless 2 0.036
bib big brain 0.035
TH1 CG9984 gene product from transcript CG9984-RA 0.035
dsh dishevelled 0.034
Psa Puromycin sensitive aminopeptidase 0.034
wb wing blister 0.033
trk trunk 0.032
repo reversed polarity 0.032
pros prospero 0.030
Top2 Topoisomerase 2 0.030
CaMKII Calcium/calmodulin-dependent protein kinase II 0.030
CG9139 CG9139 gene product from transcript CG9139-RA 0.029
disco disconnected 0.029
Scm Sex comb on midleg 0.029
endoA endophilin A 0.028
grh grainy head 0.028
Doc2 Dorsocross2 0.027
Psn Presenilin 0.027
hiw highwire 0.026
Eip63E Ecdysone-induced protein 63E 0.026
slp1 sloppy paired 1 0.026
tsl torso-like 0.025
Peb Protein ejaculatory bulb 0.025
htl heartless 0.025
tey teyrha-meyrha 0.024
frc fringe connection 0.024
sd scalloped 0.024
ab abrupt 0.024
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Mus musculus
Name Description Probability Func Analog Organism
Mapk14 mitogen-activated protein kinase 14 0.820
Prrx1 paired related homeobox 1 0.589
Msx1 homeobox, msh-like 1 0.587
Otx2 orthodenticle homolog 2 (Drosophila) 0.526
Fgfr2 fibroblast growth factor receptor 2 0.300
Chrd chordin 0.281
Bmp4 bone morphogenetic protein 4 0.271
Dlx6 distal-less homeobox 6 0.270
Nodal nodal 0.264
Prrx2 paired related homeobox 2 0.212
Rarg retinoic acid receptor, gamma 0.203
Fgfr1 fibroblast growth factor receptor 1 0.201
Dlx5 distal-less homeobox 5 0.190
Shh sonic hedgehog 0.173
Hand1 heart and neural crest derivatives expressed transcript 1 0.145
Gli3 GLI-Kruppel family member GLI3 0.125
Dlx2 distal-less homeobox 2 0.120
Gsc goosecoid homeobox 0.115
Fgf8 fibroblast growth factor 8 0.113
Tgfb2 transforming growth factor, beta 2 0.112
Hand2 heart and neural crest derivatives expressed transcript 2 0.109
Mapk8ip3 mitogen-activated protein kinase 8 interacting protein 3 0.101
Tgfbr2 transforming growth factor, beta receptor II 0.082
Acvr1 activin A receptor, type 1 0.072
Smo smoothened homolog (Drosophila) 0.068
Bmp2 bone morphogenetic protein 2 0.066
Pten phosphatase and tensin homolog 0.065
Bmp7 bone morphogenetic protein 7 0.045
Sox9 SRY-box containing gene 9 0.042
Tbx1 T-box 1 0.041
Atf2 activating transcription factor 2 0.039
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.036
Foxc1 forkhead box C1 0.036
Ece1 endothelin converting enzyme 1 0.035
Mapk8 mitogen-activated protein kinase 8 0.033
Gbx2 gastrulation brain homeobox 2 0.032
Lhx1 LIM homeobox protein 1 0.030
Mapk11 mitogen-activated protein kinase 11 0.028
Ednra endothelin receptor type A 0.028
Pbx1 pre B-cell leukemia transcription factor 1 0.024
Hoxd11 homeobox D11 0.022
Zic3 zinc finger protein of the cerebellum 3 0.022
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.022
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.019
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.019
Smad1 MAD homolog 1 (Drosophila) 0.018
Msx2 homeobox, msh-like 2 0.017
Gdf3 growth differentiation factor 3 0.017
Apc adenomatosis polyposis coli 0.017
Mapk9 mitogen-activated protein kinase 9 0.017
Inhba inhibin beta-A 0.016
Kif3a kinesin family member 3A 0.015
Htt huntingtin 0.015
Rara retinoic acid receptor, alpha 0.015
Gdnf glial cell line derived neurotrophic factor 0.014
Hoxa2 homeobox A2 0.014
Rarb retinoic acid receptor, beta 0.013
Ctnnb1 catenin (cadherin associated protein), beta 1 0.012
Gdf1 growth differentiation factor 1 0.012
Twsg1 twisted gastrulation homolog 1 (Drosophila) 0.012
Lef1 lymphoid enhancer binding factor 1 0.012
Mgp matrix Gla protein 0.012
Tgfbr1 transforming growth factor, beta receptor I 0.012
Mapkapk2 MAP kinase-activated protein kinase 2 0.011
Eng endoglin 0.011
Myc myelocytomatosis oncogene 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism