The network for 'regulation of erk1 and erk2 cascade' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of erk1 and erk2 cascade

Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.

Homo sapiens
Name Description Probability Func Analog Organism
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
MAPK1 mitogen-activated protein kinase 1 1.000
MAPK14 mitogen-activated protein kinase 14 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.999
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.999
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.999
MAP2K1 mitogen-activated protein kinase kinase 1 0.999
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.998
EGFR epidermal growth factor receptor 0.997
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.995
FGFR2 fibroblast growth factor receptor 2 0.995
FYN FYN oncogene related to SRC, FGR, YES 0.994
TEK TEK tyrosine kinase, endothelial 0.993
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.992
FGFR1 fibroblast growth factor receptor 1 0.990
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.990
DUSP1 dual specificity phosphatase 1 0.990
CCR5 chemokine (C-C motif) receptor 5 0.985
MAPK3 mitogen-activated protein kinase 3 0.980
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.978
PLCG1 phospholipase C, gamma 1 0.978
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.973
GRB2 growth factor receptor-bound protein 2 0.966
ESR1 estrogen receptor 1 0.966
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.964
FGF1 fibroblast growth factor 1 (acidic) 0.962
SMN1 survival of motor neuron 1, telomeric 0.957
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.949
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.943
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.922
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.917
AXL AXL receptor tyrosine kinase 0.912
BCR breakpoint cluster region 0.901
VEGFA vascular endothelial growth factor A 0.888
CCL4 chemokine (C-C motif) ligand 4 0.878
BRAF v-raf murine sarcoma viral oncogene homolog B1 0.876
C1QA complement component 1, q subcomponent, A chain 0.873
GSK3B glycogen synthase kinase 3 beta 0.868
BCAR1 breast cancer anti-estrogen resistance 1 0.863
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.851
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.847
IL8 interleukin 8 0.845
LAT linker for activation of T cells 0.807
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.805
CCR1 chemokine (C-C motif) receptor 1 0.800
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.787
FGB fibrinogen beta chain 0.786
CAV1 caveolin 1, caveolae protein, 22kDa 0.781
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.767
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.747
RIPK2 receptor-interacting serine-threonine kinase 2 0.745
PILRA paired immunoglobin-like type 2 receptor alpha 0.743
TRAF1 TNF receptor-associated factor 1 0.732
PECAM1 platelet/endothelial cell adhesion molecule 0.720
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.714
IFNG interferon, gamma 0.705
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.700
CSNK2B casein kinase 2, beta polypeptide 0.691
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.684
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.671
MPDZ multiple PDZ domain protein 0.661
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.636
ARRB2 arrestin, beta 2 0.628
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.621
CCR7 chemokine (C-C motif) receptor 7 0.619
BIRC3 baculoviral IAP repeat containing 3 0.611
LCK lymphocyte-specific protein tyrosine kinase 0.603
IGF1R insulin-like growth factor 1 receptor 0.588
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.528
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.526
SFN stratifin 0.525
CCL2 chemokine (C-C motif) ligand 2 0.511
DUSP5 dual specificity phosphatase 5 0.511
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.485
GRB7 growth factor receptor-bound protein 7 0.456
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.456
SMAD2 SMAD family member 2 0.448
PTK2B PTK2B protein tyrosine kinase 2 beta 0.440
PTEN phosphatase and tensin homolog 0.432
IRS1 insulin receptor substrate 1 0.427
TNF tumor necrosis factor 0.407
CXCL9 chemokine (C-X-C motif) ligand 9 0.399
SMAD3 SMAD family member 3 0.391
BMPR1A bone morphogenetic protein receptor, type IA 0.385
CCL19 chemokine (C-C motif) ligand 19 0.374
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.369
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.363
MET met proto-oncogene (hepatocyte growth factor receptor) 0.363
C1QC complement component 1, q subcomponent, C chain 0.355
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.353
CCR2 chemokine (C-C motif) receptor 2 0.352
PTPRJ protein tyrosine phosphatase, receptor type, J 0.344
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.342
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.340
DUSP3 dual specificity phosphatase 3 0.337
ZFP36L1 zinc finger protein 36, C3H type-like 1 0.337
MARCO macrophage receptor with collagenous structure 0.331
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.326
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
pdgfaa platelet-derived growth factor alpha a 0.545
LOC557072 caspase recruitment domain-containing protein 11-like 0.496
atp6v0d1 ATPase, H+ transporting, V0 subunit D isoform 1 0.458
nf1a neurofibromin 1a 0.454
fzd7a frizzled homolog 7a 0.405
igf1 insulin-like growth factor 1 0.401
meis1 myeloid ecotropic viral integration 1 0.362
sox7 SRY-box containing gene 7 0.343
efnb2a ephrin B2a 0.313
fli1a friend leukemia integration 1a 0.300
ywhae1 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 0.296
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.281
fgf3 fibroblast growth factor 3 0.274
foxc1a forkhead box C1a 0.265
nod1 nucleotide-binding oligomerization domain containing 1 0.262
evx1 even-skipped homeobox 1 0.246
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.241
ptgs1 prostaglandin-endoperoxide synthase 1 0.238
odc1 ornithine decarboxylase 1 0.235
nadl1.1 neural adhesion molecule L1.1 0.231
ywhabl tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like 0.227
bmp2a bone morphogenetic protein 2a 0.226
celf1 cugbp, Elav-like family member 1 0.214
fshb follicle stimulating hormone, beta polypeptide 0.213
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.210
hoxa2b homeo box A2b 0.203
ywhaqb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b 0.203
cx43 connexin 43 0.197
nrp2a neuropilin 2a 0.193
vegfc vascular endothelial growth factor c 0.185
erbb3a v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a 0.182
spry4 sprouty (Drosophila) homolog 4 0.179
esr1 estrogen receptor 1 0.179
ephb4a eph receptor B4a 0.175
zeb1 zinc finger E-box binding homeobox 1 0.171
jag1b jagged 1b 0.165
fes feline sarcoma oncogene 0.164
rnd3a Rho family GTPase 3a 0.156
cnn2 calponin 2 0.150
fzd2 frizzled homolog 2 0.149
shha sonic hedgehog a 0.145
fgfr2 fibroblast growth factor receptor 2 0.144
sc:d812 sc:d812 0.142
dusp5 dual specificity phosphatase 5 0.139
tagln2 transgelin 2 0.138
lhb luteinizing hormone, beta polypeptide 0.131
llgl2 lethal giant larvae homolog 2 (Drosophila) 0.129
LOC567965 rho GTPase-activating protein 7-like 0.129
hoxb2a homeo box B2a 0.129
si:dkey-228g21.4 si:dkey-228g21.4 0.126
aox3 aldehyde oxidase 3 0.125
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.120
egr2a early growth response 2a 0.119
jag1a jagged 1a 0.117
wls wntless homolog (Drosophila) 0.117
ext1a exostoses (multiple) 1a 0.114
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.114
adora2aa adenosine A2a receptor a 0.113
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.112
sf3b1 splicing factor 3b, subunit 1 0.111
ywhaqa tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a 0.109
rbm39a RNA binding motif protein 39a 0.108
crip2 cysteine-rich protein 2 0.108
wtip Wilms tumor 1 interacting protein 0.106
pycard PYD and CARD domain containing 0.106
podxl podocalyxin-like 0.105
tie2 endothelium-specific receptor tyrosine kinase 2 0.104
gas6 growth arrest-specific 6 0.103
xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 0.103
gpr182 G protein-coupled receptor 182 0.101
yap1 Yes-associated protein 1 0.101
nf1b neurofibromin 1b 0.099
notch2 notch homolog 2 0.098
zgc:100933 zgc:100933 0.097
hoxa3a homeo box A3a 0.095
cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 0.093
ube2v2 ubiquitin-conjugating enzyme E2 variant 2 0.092
mapk1 mitogen-activated protein kinase 1 0.092
sparc secreted acidic cysteine rich glycoprotein 0.092
ptpn11b protein tyrosine phosphatase, non-receptor type 11, b 0.091
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.090
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.090
prox2 prospero homeobox 2 0.089
bmp4 bone morphogenetic protein 4 0.088
lndc1 ly6/neurotoxin domain containing 1 0.087
safb scaffold attachment factor B 0.086
ncam2 neural cell adhesion molecule 2 0.085
tln1 talin 1 0.085
clk4a CDC-like kinase 4a 0.084
hdac4 histone deacetylase 4 0.084
bmper BMP binding endothelial regulator 0.083
nog3 noggin 3 0.083
si:dkey-236e20.2 si:dkey-236e20.2 0.082
zgc:112982 zgc:112982 0.082
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.081
slc25a22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22 0.081
fgg fibrinogen, gamma polypeptide 0.080
pomt1 protein-O-mannosyltransferase 1 0.080
pigu phosphatidylinositol glycan anchor biosynthesis, class U 0.080
aplnra apelin receptor a 0.080
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Drosophila melanogaster
Name Description Probability Func Analog Organism
rl rolled 0.541
pnt pointed 0.371
Dsor1 Downstream of raf1 0.217
phl pole hole 0.187
mtt mangetout 0.166
dock dreadlocks 0.155
Shc SHC-adaptor protein 0.143
Ras85D Ras oncogene at 85D 0.132
aop anterior open 0.132
ash2 absent, small, or homeotic discs 2 0.115
csw corkscrew 0.096
CG6015 CG6015 gene product from transcript CG6015-RA 0.094
CG15436 CG15436 gene product from transcript CG15436-RA 0.088
baz bazooka 0.088
ksr kinase suppressor of ras 0.088
Sry-delta Serendipity delta 0.087
CG9797 CG9797 gene product from transcript CG9797-RA 0.087
drk downstream of receptor kinase 0.086
CG1024 CG1024 gene product from transcript CG1024-RB 0.085
fl(2)d female lethal d 0.071
stumps CG31317 gene product from transcript CG31317-RC 0.070
lqf liquid facets 0.070
CG10267 CG10267 gene product from transcript CG10267-RB 0.066
CdsA CDP diglyceride synthetase 0.065
Src42A Src oncogene at 42A 0.065
Akt1 CG4006 gene product from transcript CG4006-RA 0.063
Bj1 Bj1 protein 0.061
lgs legless 0.059
Taf6 TBP-associated factor 6 0.058
CG7928 CG7928 gene product from transcript CG7928-RA 0.058
gig gigas 0.056
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.056
Mkp3 Mitogen-activated protein kinase phosphatase 3 0.055
CG14220 CG14220 gene product from transcript CG14220-RA 0.054
brm brahma 0.054
RhoBTB CG5701 gene product from transcript CG5701-RA 0.053
Pkn Protein kinase related to protein kinase N 0.049
gek genghis khan 0.049
tkv thickveins 0.047
E2f2 E2F transcription factor 2 0.044
CG8159 CG8159 gene product from transcript CG8159-RB 0.044
mbc myoblast city 0.043
mael maelstrom 0.042
Saf-B Scaffold attachment factor B 0.042
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.041
Pp2B-14D Protein phosphatase 2B at 14D 0.041
pnut peanut 0.040
enok enoki mushroom 0.040
Bx42 CG8264 gene product from transcript CG8264-RA 0.039
rho rhomboid 0.038
Taf12 TBP-associated factor 12 0.037
CG7386 CG7386 gene product from transcript CG7386-RA 0.036
CG6066 CG6066 gene product from transcript CG6066-RA 0.036
CG3407 CG3407 gene product from transcript CG3407-RA 0.036
dos daughter of sevenless 0.036
CG4854 CG4854 gene product from transcript CG4854-RA 0.036
TSG101 tumor suppressor protein 101 0.035
SF1 Splicing factor 1 0.033
CG14546 CG14546 gene product from transcript CG14546-RA 0.033
Jra Jun-related antigen 0.033
Src64B Src oncogene at 64B 0.032
puc puckered 0.032
dwg deformed wings 0.032
B4 CG9239 gene product from transcript CG9239-RA 0.031
CG10139 CG10139 gene product from transcript CG10139-RA 0.031
NiPp1 Nuclear inhibitor of Protein phosphatase 1 0.031
shi shibire 0.030
Ras64B Ras oncogene at 64B 0.030
InR Insulin-like receptor 0.030
CG18764 CG18764 gene product from transcript CG18764-RA 0.030
Git CG16728 gene product from transcript CG16728-RA 0.030
sev sevenless 0.029
Taf1 TBP-associated factor 1 0.029
Rcd1 Reduction in Cnn dots 1 0.029
zfh1 Zn finger homeodomain 1 0.028
CG17568 CG17568 gene product from transcript CG17568-RA 0.028
retn retained 0.028
l(2)k14710 lethal (2) k14710 0.028
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.027
Fcp1 CG12252 gene product from transcript CG12252-RA 0.027
cdc2c CG10498 gene product from transcript CG10498-RC 0.027
Ric Ras which interacts with Calmodulin 0.027
CG13367 CG13367 gene product from transcript CG13367-RA 0.027
trem trade embargo 0.026
CG4813 CG4813 gene product from transcript CG4813-RA 0.026
Hs6st Heparan sulfate 6-O-sulfotransferase 0.026
Lis-1 Lissencephaly-1 0.026
CG1603 CG1603 gene product from transcript CG1603-RA 0.026
Vps45 Vacuolar protein sorting 45 0.026
lilli lilliputian 0.025
sty sprouty 0.025
aux auxillin 0.025
CG4424 CG4424 gene product from transcript CG4424-RA 0.025
Socs36E Suppressor of cytokine signaling at 36E 0.024
rdgB retinal degeneration B 0.024
az2 CG1605 gene product from transcript CG1605-RA 0.024
prod proliferation disrupter 0.024
sr stripe 0.024
CkIalpha Casein kinase Ialpha 0.023
crn crooked neck 0.023
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Mus musculus
Name Description Probability Func Analog Organism
Grb2 growth factor receptor bound protein 2 0.998
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.997
Inpp5d inositol polyphosphate-5-phosphatase D 0.983
Cbl Casitas B-lineage lymphoma 0.963
Lepr leptin receptor 0.932
Dok1 docking protein 1 0.919
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.906
Csf1 colony stimulating factor 1 (macrophage) 0.899
Cd22 CD22 antigen 0.881
Egfr epidermal growth factor receptor 0.880
Mapk1 mitogen-activated protein kinase 1 0.825
Lyz2 lysozyme 2 0.819
Shh sonic hedgehog 0.705
Cav1 caveolin 1, caveolae protein 0.654
Flt4 FMS-like tyrosine kinase 4 0.640
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.623
Acvr1 activin A receptor, type 1 0.619
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.607
Vegfa vascular endothelial growth factor A 0.600
Prkce protein kinase C, epsilon 0.588
Src Rous sarcoma oncogene 0.582
Cd44 CD44 antigen 0.574
Fcgr2b Fc receptor, IgG, low affinity IIb 0.554
Plcg1 phospholipase C, gamma 1 0.536
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.503
Dok2 docking protein 2 0.491
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.485
Kl klotho 0.483
Ptprc protein tyrosine phosphatase, receptor type, C 0.483
Arrb2 arrestin, beta 2 0.482
Ptk2 PTK2 protein tyrosine kinase 2 0.471
Ghr growth hormone receptor 0.465
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.458
Pten phosphatase and tensin homolog 0.428
Nf1 neurofibromatosis 1 0.427
Fgf8 fibroblast growth factor 8 0.420
Runx2 runt related transcription factor 2 0.412
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.406
Pthlh parathyroid hormone-like peptide 0.405
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.403
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.391
Spry2 sprouty homolog 2 (Drosophila) 0.384
Igf1 insulin-like growth factor 1 0.379
Nsf N-ethylmaleimide sensitive fusion protein 0.378
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.364
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.355
Ednra endothelin receptor type A 0.353
Bdnf brain derived neurotrophic factor 0.290
Insr insulin receptor 0.288
Emr1 EGF-like module containing, mucin-like, hormone receptor-like sequence 1 0.287
Adam17 a disintegrin and metallopeptidase domain 17 0.286
Ret ret proto-oncogene 0.281
Lmna lamin A 0.278
Mrc1 mannose receptor, C type 1 0.271
Abl1 c-abl oncogene 1, non-receptor tyrosine kinase 0.262
Grb10 growth factor receptor bound protein 10 0.256
Meox2 mesenchyme homeobox 2 0.256
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.253
Fcgr1 Fc receptor, IgG, high affinity I 0.252
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.244
Pgr progesterone receptor 0.238
Nrp1 neuropilin 1 0.232
C1qa complement component 1, q subcomponent, alpha polypeptide 0.227
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.225
Was Wiskott-Aldrich syndrome homolog (human) 0.224
H2-Eb1 histocompatibility 2, class II antigen E beta 0.218
Plxnd1 plexin D1 0.217
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.216
Kdr kinase insert domain protein receptor 0.214
Arrb1 arrestin, beta 1 0.207
Btk Bruton agammaglobulinemia tyrosine kinase 0.201
Tgfbr2 transforming growth factor, beta receptor II 0.200
Raf1 v-raf-leukemia viral oncogene 1 0.200
Prss32 protease, serine, 32 0.199
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.198
Homer1 homer homolog 1 (Drosophila) 0.198
Notch2 Notch gene homolog 2 (Drosophila) 0.197
Bmp5 bone morphogenetic protein 5 0.193
Rxra retinoid X receptor alpha 0.191
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.189
Ltb lymphotoxin B 0.187
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 0.186
Ntf3 neurotrophin 3 0.180
Sox9 SRY-box containing gene 9 0.179
Fgfr3 fibroblast growth factor receptor 3 0.178
Gbp5 guanylate binding protein 5 0.177
Cckbr cholecystokinin B receptor 0.176
H2-Aa histocompatibility 2, class II antigen A, alpha 0.175
Ccl4 chemokine (C-C motif) ligand 4 0.175
Crhr1 corticotropin releasing hormone receptor 1 0.175
Oc90 otoconin 90 0.174
Gnb3 guanine nucleotide binding protein (G protein), beta 3 0.174
Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.172
Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) 0.169
Col1a1 collagen, type I, alpha 1 0.168
Cyld cylindromatosis (turban tumor syndrome) 0.167
Traf6 TNF receptor-associated factor 6 0.167
Il1r1 interleukin 1 receptor, type I 0.165
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.165
Vegfc vascular endothelial growth factor C 0.165
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Rattus norvegicus
Name Description Probability Func Analog Organism
Egr1 early growth response 1 0.578
Cav1 caveolin 1, caveolae protein 0.339
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.264
Sirpa signal-regulatory protein alpha 0.262
Inpp5d inositol polyphosphate-5-phosphatase D 0.213
Ccl4 chemokine (C-C motif) ligand 4 0.171
Grin2b glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.132
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.127
Cd4 Cd4 molecule 0.126
Fos FBJ osteosarcoma oncogene 0.113
Ptprc protein tyrosine phosphatase, receptor type, C 0.112
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.111
Junb jun B proto-oncogene 0.103
LOC100362824 caveolin 2-like 0.100
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.097
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.095
Jak1 Janus kinase 1 0.092
Ncan neurocan 0.091
Gcm1 glial cells missing homolog 1 (Drosophila) 0.088
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.084
Foxe3 forkhead box E3 0.083
Hrh3 histamine receptor H3 0.083
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.083
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.082
Robo1 roundabout homolog 1 (Drosophila) 0.081
Cxcl2 chemokine (C-X-C motif) ligand 2 0.080
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.078
Mr1 major histocompatibility complex, class I-related 0.077
Tcf4 transcription factor 4 0.077
Adrb1 adrenergic, beta-1-, receptor 0.077
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.075
Wipf1 WAS/WASL interacting protein family, member 1 0.073
Rho rhodopsin 0.070
Nop58 nucleolar protein NOP58 0.069
Il1a interleukin 1 alpha 0.069
Hck hemopoietic cell kinase 0.069
Phkg1 phosphorylase kinase, gamma 1 0.067
Btg2 BTG family, member 2 0.067
Agtr1a angiotensin II receptor, type 1a 0.065
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.062
Ptgs2 prostaglandin-endoperoxide synthase 2 0.060
Klf2 Kruppel-like factor 2 (lung) 0.059
Sst somatostatin 0.059
Dock8 dedicator of cytokinesis 8 0.059
Prkcd protein kinase C, delta 0.058
Jdp2 Jun dimerization protein 2 0.058
RGD1564664 similar to LOC387763 protein 0.058
Esr2 estrogen receptor 2 (ER beta) 0.058
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.057
Cdh6 cadherin 6 0.057
Cd2 Cd2 molecule 0.057
Il1b interleukin 1 beta 0.057
Atxn1 ataxin 1 0.055
Nrarp Notch-regulated ankyrin repeat protein 0.054
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.053
Samsn1 SAM domain, SH3 domain and nuclear localization signals, 1 0.052
Il24 interleukin 24 0.050
Usf2 upstream transcription factor 2, c-fos interacting 0.050
Creb1 cAMP responsive element binding protein 1 0.050
Vav1 vav 1 guanine nucleotide exchange factor 0.050
Gdnf glial cell derived neurotrophic factor 0.049
Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 0.049
Grk4 G protein-coupled receptor kinase 4 0.049
Prrx1 paired related homeobox 1 0.048
Prkch protein kinase C, eta 0.048
Ier2 immediate early response 2 0.048
Add3 adducin 3 (gamma) 0.048
Prdm2 PR domain containing 2, with ZNF domain 0.048
Gnat1 guanine nucleotide binding protein (G protein), alpha transducing 1 0.047
Vipr1 vasoactive intestinal peptide receptor 1 0.047
RGD1560559 similar to RIKEN cDNA 2310042E22 0.047
Tlr7 toll-like receptor 7 0.046
Chrna7 cholinergic receptor, nicotinic, alpha 7 0.046
Ptafr platelet-activating factor receptor 0.046
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.045
Dbp D site of albumin promoter (albumin D-box) binding protein 0.045
Socs3 suppressor of cytokine signaling 3 0.045
Ncr1 natural cytotoxicity triggering receptor 1 0.045
Grm8 glutamate receptor, metabotropic 8 0.044
Mmp9 matrix metallopeptidase 9 0.044
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.043
Olr1867 olfactory receptor 1867 0.043
Sf3b1 splicing factor 3b, subunit 1 0.042
Itgam integrin, alpha M 0.042
Fgf5 fibroblast growth factor 5 0.041
Oprm1 opioid receptor, mu 1 0.041
Cd37 CD37 molecule 0.040
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.040
Kcnj4 potassium inwardly-rectifying channel, subfamily J, member 4 0.040
Sstr5 somatostatin receptor 5 0.040
RT1-DMb RT1 class II, locus DMb 0.040
Gjb4 gap junction protein, beta 4 0.039
Klf6 Kruppel-like factor 6 0.039
Rhog ras homolog gene family, member G (rho G) 0.039
Tgfbr2 transforming growth factor, beta receptor II 0.039
Rasgrp1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) 0.039
Drd3 dopamine receptor D3 0.038
Bcan brevican 0.038
Il9r interleukin 9 receptor 0.037
Apol3 apolipoprotein L, 3 0.037
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism