IMP
Process View
The network for 'transcription factor import into nucleus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
transcription factor import into nucleus
The directed movement of a transcription factor from the cytoplasm to the nucleus.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SMAD3 | SMAD family member 3 | 0.992 | |
| LAT | linker for activation of T cells | 0.855 | |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.716 | |
| MYD88 | myeloid differentiation primary response gene (88) | 0.681 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.592 | |
| BTRC | beta-transducin repeat containing | 0.570 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.536 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.529 | |
| SMAD2 | SMAD family member 2 | 0.502 | |
| GRB2 | growth factor receptor-bound protein 2 | 0.483 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.436 | |
| IL1R1 | interleukin 1 receptor, type I | 0.427 | |
| SH2D4A | SH2 domain containing 4A | 0.398 | |
| SH3BP2 | SH3-domain binding protein 2 | 0.338 | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.331 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.309 | |
| RANBP3 | RAN binding protein 3 | 0.275 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.272 | |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.253 | |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | 0.199 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.196 | |
| SMAD7 | SMAD family member 7 | 0.191 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.190 | |
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.175 | |
| EGFR | epidermal growth factor receptor | 0.174 | |
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.165 | |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.164 | |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.161 | |
| IL8 | interleukin 8 | 0.157 | |
| KPNB1 | karyopherin (importin) beta 1 | 0.145 | |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.145 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.135 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.127 | |
| RNF31 | ring finger protein 31 | 0.118 | |
| SMAD4 | SMAD family member 4 | 0.118 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.114 | |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.113 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.107 | |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.099 | |
| IGF1R | insulin-like growth factor 1 receptor | 0.098 | |
| IL1B | interleukin 1, beta | 0.096 | |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) | 0.094 | |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.088 | |
| PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.086 | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.075 | |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.074 | |
| CKAP5 | cytoskeleton associated protein 5 | 0.070 | |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.070 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.068 | |
| FLNB | filamin B, beta | 0.068 | |
| YAP1 | Yes-associated protein 1 | 0.067 | |
| SYK | spleen tyrosine kinase | 0.067 | |
| RACGAP1 | Rac GTPase activating protein 1 | 0.065 | |
| LY96 | lymphocyte antigen 96 | 0.065 | |
| TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.064 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.063 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.063 | |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.062 | |
| AXIN1 | axin 1 | 0.062 | |
| XIRP1 | xin actin-binding repeat containing 1 | 0.062 | |
| PSEN1 | presenilin 1 | 0.061 | |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.061 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.060 | |
| SMAD1 | SMAD family member 1 | 0.060 | |
| ZNF84 | zinc finger protein 84 | 0.060 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.060 | |
| WDR26 | WD repeat domain 26 | 0.060 | |
| MAVS | mitochondrial antiviral signaling protein | 0.059 | |
| IRF7 | interferon regulatory factor 7 | 0.058 | |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.058 | |
| HDAC6 | histone deacetylase 6 | 0.058 | |
| ACTN4 | actinin, alpha 4 | 0.057 | |
| IL1R2 | interleukin 1 receptor, type II | 0.057 | |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 0.056 | |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.056 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.055 | |
| SKIL | SKI-like oncogene | 0.054 | |
| DSG2 | desmoglein 2 | 0.054 | |
| TNF | tumor necrosis factor | 0.053 | |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain | 0.053 | |
| ZNF260 | zinc finger protein 260 | 0.050 | |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.050 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.048 | |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.047 | |
| TXN | thioredoxin | 0.047 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.046 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.045 | |
| PML | promyelocytic leukemia | 0.045 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.045 | |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.045 | |
| VCL | vinculin | 0.045 | |
| TLR2 | toll-like receptor 2 | 0.045 | |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.044 | |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.044 | |
| ZNF420 | zinc finger protein 420 | 0.043 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.043 | |
| RECQL | RecQ protein-like (DNA helicase Q1-like) | 0.042 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.042 | |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.041 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.041 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Tnf | tumor necrosis factor | 0.930 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.859 | |
| Il1r1 | interleukin 1 receptor, type I | 0.671 | |
| Apc | adenomatosis polyposis coli | 0.489 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.300 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.298 | |
| Lta | lymphotoxin A | 0.297 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.238 | |
| Ppp3r1 | protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) | 0.224 | |
| Trp63 | transformation related protein 63 | 0.217 | |
| Edaradd | EDAR (ectodysplasin-A receptor)-associated death domain | 0.211 | |
| Il6st | interleukin 6 signal transducer | 0.206 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.200 | |
| Tnfrsf1b | tumor necrosis factor receptor superfamily, member 1b | 0.198 | |
| Pten | phosphatase and tensin homolog | 0.173 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.171 | |
| Ar | androgen receptor | 0.156 | |
| Nfkb1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 | 0.145 | |
| Casp1 | caspase 1 | 0.140 | |
| Il6 | interleukin 6 | 0.135 | |
| Rara | retinoic acid receptor, alpha | 0.134 | |
| Lyz2 | lysozyme 2 | 0.126 | |
| Cd40 | CD40 antigen | 0.124 | |
| Fas | Fas (TNF receptor superfamily member 6) | 0.121 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.114 | |
| Trp53 | transformation related protein 53 | 0.110 | |
| Pik3cd | phosphatidylinositol 3-kinase catalytic delta polypeptide | 0.108 | |
| Rarg | retinoic acid receptor, gamma | 0.107 | |
| Mapkap1 | mitogen-activated protein kinase associated protein 1 | 0.103 | |
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.099 | |
| Htt | huntingtin | 0.098 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.092 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.091 | |
| Rxra | retinoid X receptor alpha | 0.086 | |
| Psen1 | presenilin 1 | 0.085 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.081 | |
| Ncoa3 | nuclear receptor coactivator 3 | 0.080 | |
| Relb | avian reticuloendotheliosis viral (v-rel) oncogene related B | 0.075 | |
| Cd44 | CD44 antigen | 0.075 | |
| Pkd1 | polycystic kidney disease 1 homolog | 0.074 | |
| Il7 | interleukin 7 | 0.071 | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.070 | |
| Dbp | D site albumin promoter binding protein | 0.067 | |
| Ikbkg | inhibitor of kappaB kinase gamma | 0.063 | |
| Per1 | period homolog 1 (Drosophila) | 0.062 | |
| Bmp4 | bone morphogenetic protein 4 | 0.059 | |
| Grb10 | growth factor receptor bound protein 10 | 0.056 | |
| Lepr | leptin receptor | 0.055 | |
| Smo | smoothened homolog (Drosophila) | 0.054 | |
| Il10 | interleukin 10 | 0.053 | |
| Axin1 | axin 1 | 0.052 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.051 | |
| Cand1 | cullin associated and neddylation disassociated 1 | 0.051 | |
| Sox9 | SRY-box containing gene 9 | 0.049 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.049 | |
| Vdr | vitamin D receptor | 0.048 | |
| Myd88 | myeloid differentiation primary response gene 88 | 0.048 | |
| Hs1bp3 | HCLS1 binding protein 3 | 0.046 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.045 | |
| Srrt | serrate RNA effector molecule homolog (Arabidopsis) | 0.044 | |
| Il1b | interleukin 1 beta | 0.044 | |
| Stim2 | stromal interaction molecule 2 | 0.044 | |
| Fam96a | family with sequence similarity 96, member A | 0.043 | |
| Ptpn22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) | 0.042 | |
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.041 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.041 | |
| Rel | reticuloendotheliosis oncogene | 0.041 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.041 | |
| Cd28 | CD28 antigen | 0.041 | |
| Il1r2 | interleukin 1 receptor, type II | 0.040 | |
| Ppp3cb | protein phosphatase 3, catalytic subunit, beta isoform | 0.040 | |
| Rptor | regulatory associated protein of MTOR, complex 1 | 0.039 | |
| Tlr4 | toll-like receptor 4 | 0.039 | |
| Lancl2 | LanC (bacterial lantibiotic synthetase component C)-like 2 | 0.038 | |
| Cux1 | cut-like homeobox 1 | 0.038 | |
| Kif20a | kinesin family member 20A | 0.037 | |
| Yap1 | yes-associated protein 1 | 0.037 | |
| Cbx5 | chromobox homolog 5 (Drosophila HP1a) | 0.037 | |
| Nodal | nodal | 0.037 | |
| Anapc2 | anaphase promoting complex subunit 2 | 0.037 | |
| Ptch1 | patched homolog 1 | 0.036 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.035 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.035 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.034 | |
| Rnf115 | ring finger protein 115 | 0.034 | |
| Gspt1 | G1 to S phase transition 1 | 0.034 | |
| Il18rap | interleukin 18 receptor accessory protein | 0.034 | |
| Smad2 | MAD homolog 2 (Drosophila) | 0.034 | |
| Traf3 | TNF receptor-associated factor 3 | 0.034 | |
| Ltb | lymphotoxin B | 0.033 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.033 | |
| Slc12a6 | solute carrier family 12, member 6 | 0.032 | |
| Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.032 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.032 | |
| Lhx1 | LIM homeobox protein 1 | 0.032 | |
| Pom121 | nuclear pore membrane protein 121 | 0.031 | |
| Il1a | interleukin 1 alpha | 0.031 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.031 | |
| Kpna1 | karyopherin (importin) alpha 1 | 0.031 | |
| Tox | thymocyte selection-associated high mobility group box | 0.031 |