The network for 'mammary gland lobule development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mammary gland lobule development

The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.

Name Description Probability Func Analog Organism
Lepr leptin receptor 1.000
Tnf tumor necrosis factor 0.989
Esr1 estrogen receptor 1 (alpha) 0.930
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.926
Stat5a signal transducer and activator of transcription 5A 0.919
Hoxb5 homeobox B5 0.841
Stat3 signal transducer and activator of transcription 3 0.830
Id3 inhibitor of DNA binding 3 0.823
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.811
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.802
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.797
Id1 inhibitor of DNA binding 1 0.796
Chuk conserved helix-loop-helix ubiquitous kinase 0.793
Hoxb6 homeobox B6 0.763
Lep leptin 0.733
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.719
Ltb lymphotoxin B 0.713
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.703
Hoxd9 homeobox D9 0.699
Ifng interferon gamma 0.673
Nos3 nitric oxide synthase 3, endothelial cell 0.666
Pgr progesterone receptor 0.665
Hoxa9 homeobox A9 0.651
Cdk6 cyclin-dependent kinase 6 0.648
Hoxc8 homeobox C8 0.642
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.637
Hoxb3 homeobox B3 0.630
Ptgs2 prostaglandin-endoperoxide synthase 2 0.623
Igh immunoglobulin heavy chain complex 0.619
Hoxa1 homeobox A1 0.589
Egfr epidermal growth factor receptor 0.559
Hoxa5 homeobox A5 0.545
Hoxb9 homeobox B9 0.527
Ikbkg inhibitor of kappaB kinase gamma 0.519
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.480
Cd40 CD40 antigen 0.478
Hoxc6 homeobox C6 0.471
Insr insulin receptor 0.439
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.432
Ghr growth hormone receptor 0.432
Hoxa10 homeobox A10 0.428
Npy1r neuropeptide Y receptor Y1 0.362
Lta lymphotoxin A 0.352
Kl klotho 0.343
Cav1 caveolin 1, caveolae protein 0.334
Tbx3 T-box 3 0.328
Flt4 FMS-like tyrosine kinase 4 0.310
Hoxd8 homeobox D8 0.309
Hoxb4 homeobox B4 0.299
Hoxb8 homeobox B8 0.283
Nos1 nitric oxide synthase 1, neuronal 0.281
Socs1 suppressor of cytokine signaling 1 0.279
Hoxd4 homeobox D4 0.278
Il10 interleukin 10 0.275
Stat5b signal transducer and activator of transcription 5B 0.271
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.266
Sox7 SRY-box containing gene 7 0.266
Esr2 estrogen receptor 2 (beta) 0.266
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.259
Foxf1a forkhead box F1a 0.252
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.244
Pbx1 pre B-cell leukemia transcription factor 1 0.243
Fas Fas (TNF receptor superfamily member 6) 0.238
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.238
Csf2 colony stimulating factor 2 (granulocyte-macrophage) 0.235
Fgfr2 fibroblast growth factor receptor 2 0.227
Hoxc5 homeobox C5 0.223
Hoxd10 homeobox D10 0.212
Tcf3 transcription factor 3 0.196
Tbx2 T-box 2 0.192
Kiss1 KiSS-1 metastasis-suppressor 0.190
Hoxc9 homeobox C9 0.186
Ikzf1 IKAROS family zinc finger 1 0.185
Hoxc4 homeobox C4 0.184
Twist2 twist homolog 2 (Drosophila) 0.182
Sim1 single-minded homolog 1 (Drosophila) 0.182
Pitx2 paired-like homeodomain transcription factor 2 0.170
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.169
Trp53 transformation related protein 53 0.166
Pax8 paired box gene 8 0.164
Il1r1 interleukin 1 receptor, type I 0.161
Smad6 MAD homolog 6 (Drosophila) 0.158
Fshr follicle stimulating hormone receptor 0.148
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.143
Foxn1 forkhead box N1 0.139
Il6 interleukin 6 0.138
Phox2b paired-like homeobox 2b 0.133
Hoxa2 homeobox A2 0.127
Tcf4 transcription factor 4 0.124
Tox thymocyte selection-associated high mobility group box 0.123
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.123
Pten phosphatase and tensin homolog 0.118
Tgfa transforming growth factor alpha 0.110
Cish cytokine inducible SH2-containing protein 0.105
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.104
Egln1 EGL nine homolog 1 (C. elegans) 0.103
Pnpla2 patatin-like phospholipase domain containing 2 0.102
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.100
Hoxb2 homeobox B2 0.100
Itga3 integrin alpha 3 0.099
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism