The network for 'mammary gland epithelium development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mammary gland epithelium development

The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.

Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 1.000
Pax8 paired box gene 8 0.999
Gli3 GLI-Kruppel family member GLI3 0.999
Lepr leptin receptor 0.998
Trp53 transformation related protein 53 0.998
Pten phosphatase and tensin homolog 0.995
Tbx3 T-box 3 0.993
Gli2 GLI-Kruppel family member GLI2 0.992
Shh sonic hedgehog 0.991
Apc adenomatosis polyposis coli 0.990
Zeb1 zinc finger E-box binding homeobox 1 0.979
Esr1 estrogen receptor 1 (alpha) 0.969
Socs1 suppressor of cytokine signaling 1 0.966
Fgfr1 fibroblast growth factor receptor 1 0.959
Robo1 roundabout homolog 1 (Drosophila) 0.957
Csf1 colony stimulating factor 1 (macrophage) 0.950
Ctnnb1 catenin (cadherin associated protein), beta 1 0.940
Ar androgen receptor 0.937
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.936
Igh immunoglobulin heavy chain complex 0.934
Pax2 paired box gene 2 0.885
Pitx2 paired-like homeodomain transcription factor 2 0.871
Smad4 MAD homolog 4 (Drosophila) 0.863
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.854
Sox2 SRY-box containing gene 2 0.844
Ptch1 patched homolog 1 0.833
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.832
Rarg retinoic acid receptor, gamma 0.832
Pitx1 paired-like homeodomain transcription factor 1 0.822
Fgfr3 fibroblast growth factor receptor 3 0.812
Lhx1 LIM homeobox protein 1 0.809
Bmp4 bone morphogenetic protein 4 0.797
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.789
Hoxa1 homeobox A1 0.781
Meox2 mesenchyme homeobox 2 0.778
Hoxd11 homeobox D11 0.769
Rara retinoic acid receptor, alpha 0.763
Sox9 SRY-box containing gene 9 0.745
Hoxa5 homeobox A5 0.732
Hoxc9 homeobox C9 0.732
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.728
Hoxd9 homeobox D9 0.721
Stat3 signal transducer and activator of transcription 3 0.709
Tbx2 T-box 2 0.707
Gata4 GATA binding protein 4 0.701
Slit2 slit homolog 2 (Drosophila) 0.685
Kl klotho 0.683
Pparg peroxisome proliferator activated receptor gamma 0.681
Prrx1 paired related homeobox 1 0.680
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.677
Pax3 paired box gene 3 0.658
Sfpi1 SFFV proviral integration 1 0.649
Stat5a signal transducer and activator of transcription 5A 0.648
Lep leptin 0.647
Gdnf glial cell line derived neurotrophic factor 0.647
Nodal nodal 0.632
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.629
Tcf21 transcription factor 21 0.627
Twist2 twist homolog 2 (Drosophila) 0.614
Insr insulin receptor 0.612
Pthlh parathyroid hormone-like peptide 0.612
Trp63 transformation related protein 63 0.605
Ikzf1 IKAROS family zinc finger 1 0.600
Cd40 CD40 antigen 0.600
Egfr epidermal growth factor receptor 0.592
Lrp5 low density lipoprotein receptor-related protein 5 0.589
Bcl2 B-cell leukemia/lymphoma 2 0.588
Hoxb6 homeobox B6 0.585
Id1 inhibitor of DNA binding 1 0.562
Jak2 Janus kinase 2 0.561
Foxc1 forkhead box C1 0.541
Lrp6 low density lipoprotein receptor-related protein 6 0.523
Amhr2 anti-Mullerian hormone type 2 receptor 0.514
Ncoa3 nuclear receptor coactivator 3 0.509
Lif leukemia inhibitory factor 0.501
Wnt5a wingless-related MMTV integration site 5A 0.501
Sim2 single-minded homolog 2 (Drosophila) 0.497
Efnb2 ephrin B2 0.493
Cdk6 cyclin-dependent kinase 6 0.481
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.479
Pbx1 pre B-cell leukemia transcription factor 1 0.478
Nf1 neurofibromatosis 1 0.478
Pitx3 paired-like homeodomain transcription factor 3 0.472
Cd19 CD19 antigen 0.463
Brca1 breast cancer 1 0.457
Myod1 myogenic differentiation 1 0.455
Id3 inhibitor of DNA binding 3 0.448
Fgf8 fibroblast growth factor 8 0.445
Sox11 SRY-box containing gene 11 0.426
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.426
Ccnd1 cyclin D1 0.403
Thra thyroid hormone receptor alpha 0.402
Prlr prolactin receptor 0.394
Hand1 heart and neural crest derivatives expressed transcript 1 0.383
Wnt3a wingless-related MMTV integration site 3A 0.382
Unc5c unc-5 homolog C (C. elegans) 0.367
Msx2 homeobox, msh-like 2 0.365
Otx2 orthodenticle homolog 2 (Drosophila) 0.362
Prkcd protein kinase C, delta 0.362
Stat2 signal transducer and activator of transcription 2 0.355
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
ESR1 estrogen receptor 1 0.372
CREBBP CREB binding protein 0.229
TAL1 T-cell acute lymphocytic leukemia 1 0.198
NCOA1 nuclear receptor coactivator 1 0.154
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.069
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.063
TP53 tumor protein p53 0.057
HIPK2 homeodomain interacting protein kinase 2 0.053
CDK6 cyclin-dependent kinase 6 0.050
EGFR epidermal growth factor receptor 0.043
RUNX1 runt-related transcription factor 1 0.038
STAT5A signal transducer and activator of transcription 5A 0.035
CCND3 cyclin D3 0.035
FGF1 fibroblast growth factor 1 (acidic) 0.033
SP1 Sp1 transcription factor 0.032
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.031
RARA retinoic acid receptor, alpha 0.024
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.023
IL4R interleukin 4 receptor 0.022
CDK4 cyclin-dependent kinase 4 0.022
SOCS1 suppressor of cytokine signaling 1 0.021
TM4SF1 transmembrane 4 L six family member 1 0.021
CCND1 cyclin D1 0.019
FGF10 fibroblast growth factor 10 0.019
HR hairless homolog (mouse) 0.018
DAXX death-domain associated protein 0.018
BCL9 B-cell CLL/lymphoma 9 0.018
S100A4 S100 calcium binding protein A4 0.018
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.017
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.017
NCOR2 nuclear receptor corepressor 2 0.016
BCL2 B-cell CLL/lymphoma 2 0.015
DDX17 DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 0.015
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.014
INSR insulin receptor 0.014
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.014
RXRA retinoid X receptor, alpha 0.014
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.014
FBXW11 F-box and WD repeat domain containing 11 0.012
ENG endoglin 0.012
S100A2 S100 calcium binding protein A2 0.012
CAV1 caveolin 1, caveolae protein, 22kDa 0.012
GSK3B glycogen synthase kinase 3 beta 0.011
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.011
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Rattus norvegicus
Name Description Probability Func Analog Organism
Unc5b unc-5 homolog B (C. elegans) 0.070
Ralgds ral guanine nucleotide dissociation stimulator 0.061
Errfi1 ERBB receptor feedback inhibitor 1 0.053
Smad7 SMAD family member 7 0.053
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.047
Olr1469 olfactory receptor Olr1469 0.046
Rara retinoic acid receptor, alpha 0.045
Bcl2 B-cell CLL/lymphoma 2 0.044
Sirpa signal-regulatory protein alpha 0.042
Ptbp1 polypyrimidine tract binding protein 1 0.037
Bmp7 bone morphogenetic protein 7 0.037
Jak1 Janus kinase 1 0.037
Gata6 GATA binding protein 6 0.036
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.033
Homer1 homer homolog 1 (Drosophila) 0.028
Aif1l allograft inflammatory factor 1-like 0.027
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.027
Nfic nuclear factor I/C 0.025
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.025
Capn5 calpain 5 0.024
Sdc1 syndecan 1 0.024
Pls3 plastin 3 (T-isoform) 0.024
Rab1 RAB1, member RAS oncogene family 0.023
Tmem79 transmembrane protein 79 0.022
Map2k1 mitogen activated protein kinase kinase 1 0.022
Obp3 alpha-2u globulin PGCL4 0.022
Met met proto-oncogene 0.022
Mapk14 mitogen activated protein kinase 14 0.022
Vegfa vascular endothelial growth factor A 0.022
Il6r interleukin 6 receptor 0.021
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.021
Picalm phosphatidylinositol binding clathrin assembly protein 0.021
Gna12 guanine nucleotide binding protein (G protein) alpha 12 0.021
Fgfr1 Fibroblast growth factor receptor 1 0.020
Myh9 myosin, heavy chain 9, non-muscle 0.020
RGD1564327 similar to integrin alpha 8 0.020
Adrb1 adrenergic, beta-1-, receptor 0.020
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.020
Shox2 short stature homeobox 2 0.019
Kl Klotho 0.019
Mid1 midline 1 0.019
Foxe3 forkhead box E3 0.019
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.019
Prkca protein kinase C, alpha 0.018
Rin1 Ras and Rab interactor 1 0.018
St13 suppression of tumorigenicity 13 0.018
Palm paralemmin 0.018
Ptpn1 protein tyrosine phosphatase, non-receptor type 1 0.018
S1pr2 sphingosine-1-phosphate receptor 2 0.018
Tfeb transcription factor EB 0.018
Ugt8 UDP glycosyltransferase 8 0.017
Cga glycoprotein hormones, alpha polypeptide 0.017
Rala v-ral simian leukemia viral oncogene homolog A (ras related) 0.017
Sppl2b signal peptide peptidase-like 2B 0.017
Myo1d myosin ID 0.017
Mycs myc-like oncogene, s-myc protein 0.017
Mdm2 Mdm2 p53 binding protein homolog (mouse) 0.017
Rxra retinoid X receptor alpha 0.017
Aqp4 aquaporin 4 0.016
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.016
Homer3 homer homolog 3 (Drosophila) 0.016
Gja5 gap junction protein, alpha 5 0.016
Stx6 syntaxin 6 0.016
Ccnd3 cyclin D3 0.016
Hr hairless 0.016
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 0.016
Dcc deleted in colorectal carcinoma 0.016
Fnbp1 formin binding protein 1 0.016
Usf2 upstream transcription factor 2, c-fos interacting 0.016
Psen1 presenilin 1 0.016
Smad3 SMAD family member 3 0.015
Smo smoothened homolog (Drosophila) 0.015
Tgfbr2 transforming growth factor, beta receptor II 0.015
Sf1 splicing factor 1 0.015
Ddr1 discoidin domain receptor tyrosine kinase 1 0.015
Ube3a ubiquitin protein ligase E3A 0.015
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.015
Gdnf glial cell derived neurotrophic factor 0.015
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.015
Tef thyrotrophic embryonic factor 0.015
Galr2 galanin receptor 2 0.015
Arhgef1 Rho guanine nucleotide exchange factor (GEF) 1 0.015
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.015
Cckar cholecystokinin A receptor 0.015
Foxd3 forkhead box D3 0.015
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.015
Casq1 calsequestrin 1 (fast-twitch, skeletal muscle) 0.015
Pfkfb2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 0.015
Adrb3 adrenergic, beta-3-, receptor 0.014
G3bp2 GTPase activating protein (SH3 domain) binding protein 2 0.014
Csnk1g1 casein kinase 1, gamma 1 0.014
Smad1 SMAD family member 1 0.014
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.014
Cyth1 cytohesin 1 0.014
Cish cytokine inducible SH2-containing protein 0.014
LOC64038 sertolin 0.014
Sox17 SRY (sex determining region Y)-box 17 0.014
Adra2a adrenergic, alpha-2A-, receptor 0.014
Adora1 adenosine A1 receptor 0.014
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.014
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism