The network for 'regulation of defense response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of defense response

Any process that modulates the frequency, rate or extent of a defense response.

Mus musculus
Name Description Probability Func Analog Organism
Tlr4 toll-like receptor 4 1.000
Stat3 signal transducer and activator of transcription 3 1.000
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.999
Clock circadian locomotor output cycles kaput 0.999
Stat1 signal transducer and activator of transcription 1 0.998
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.997
Casp1 caspase 1 0.997
Tnf tumor necrosis factor 0.996
Traf6 TNF receptor-associated factor 6 0.996
Lyz2 lysozyme 2 0.996
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.996
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.995
Apoe apolipoprotein E 0.994
Casp8 caspase 8 0.988
Gbp2 guanylate binding protein 2 0.984
Myd88 myeloid differentiation primary response gene 88 0.982
Gbp7 guanylate binding protein 7 0.982
C3 complement component 3 0.980
Cd40 CD40 antigen 0.971
Ikbkg inhibitor of kappaB kinase gamma 0.970
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.970
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.967
Birc3 baculoviral IAP repeat-containing 3 0.964
Il10ra interleukin 10 receptor, alpha 0.962
Batf basic leucine zipper transcription factor, ATF-like 0.960
Irf7 interferon regulatory factor 7 0.960
Irf1 interferon regulatory factor 1 0.959
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.954
Stat6 signal transducer and activator of transcription 6 0.953
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.949
Slamf1 signaling lymphocytic activation molecule family member 1 0.947
Mapk14 mitogen-activated protein kinase 14 0.946
Iigp1 interferon inducible GTPase 1 0.946
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.945
Gbp3 guanylate binding protein 3 0.942
Pax8 paired box gene 8 0.941
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.940
Trim21 tripartite motif-containing 21 0.939
Il1b interleukin 1 beta 0.937
Il4ra interleukin 4 receptor, alpha 0.935
Smad4 MAD homolog 4 (Drosophila) 0.934
Ifi203 interferon activated gene 203 0.931
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.926
Parp14 poly (ADP-ribose) polymerase family, member 14 0.920
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.919
Atf2 activating transcription factor 2 0.919
Irgm1 immunity-related GTPase family M member 1 0.919
Ikbkb inhibitor of kappaB kinase beta 0.917
Nlrp3 NLR family, pyrin domain containing 3 0.914
Gzmk granzyme K 0.912
Axl AXL receptor tyrosine kinase 0.899
Fasl Fas ligand (TNF superfamily, member 6) 0.894
Cyld cylindromatosis (turban tumor syndrome) 0.894
H2-K1 histocompatibility 2, K1, K region 0.893
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.893
Nos2 nitric oxide synthase 2, inducible 0.893
Aoah acyloxyacyl hydrolase 0.893
Traf1 TNF receptor-associated factor 1 0.892
Unc93b1 unc-93 homolog B1 (C. elegans) 0.885
Junb Jun-B oncogene 0.884
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.883
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.883
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.882
Trim30a tripartite motif-containing 30A 0.877
Il18r1 interleukin 18 receptor 1 0.876
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.876
Ptgs2 prostaglandin-endoperoxide synthase 2 0.875
Fos FBJ osteosarcoma oncogene 0.875
Ccl2 chemokine (C-C motif) ligand 2 0.868
Pdcd1lg2 programmed cell death 1 ligand 2 0.861
Cfh complement component factor h 0.859
Il18rap interleukin 18 receptor accessory protein 0.850
Pten phosphatase and tensin homolog 0.850
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.845
Cxcl10 chemokine (C-X-C motif) ligand 10 0.841
Egr2 early growth response 2 0.833
Prdm1 PR domain containing 1, with ZNF domain 0.830
Ccl8 chemokine (C-C motif) ligand 8 0.827
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.826
Irf9 interferon regulatory factor 9 0.825
Il1rn interleukin 1 receptor antagonist 0.823
H2-Q7 histocompatibility 2, Q region locus 7 0.822
Fas Fas (TNF receptor superfamily member 6) 0.820
Gzmb granzyme B 0.816
Pparg peroxisome proliferator activated receptor gamma 0.816
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.814
Fgr Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog 0.812
Icos inducible T-cell co-stimulator 0.811
Cd33 CD33 antigen 0.811
Cd44 CD44 antigen 0.809
Pax2 paired box gene 2 0.792
Mefv Mediterranean fever 0.792
Il2rb interleukin 2 receptor, beta chain 0.790
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.779
Ccr1 chemokine (C-C motif) receptor 1 0.777
Cd180 CD180 antigen 0.768
Clec4n C-type lectin domain family 4, member n 0.767
Per2 period homolog 2 (Drosophila) 0.761
Il10 interleukin 10 0.759
Smad1 MAD homolog 1 (Drosophila) 0.758
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
C52E12.4 Protein C52E12.4 0.043
unc-94 Protein UNC-94 0.030
sax-3 Protein SAX-3 0.030
glh-1 Protein GLH-1 0.028
egl-27 Protein EGL-27 0.027
Y22D7AL.10 Protein Y22D7AL.10 0.027
sur-2 Protein SUR-2 0.026
ceh-44 Protein CEH-44 0.024
unc-32 Protein UNC-32 0.024
dmd-6 Protein DMD-6 0.022
egl-30 Protein EGL-30 0.021
eat-4 Protein EAT-4 0.019
F41C3.8 Protein F41C3.8 0.018
glr-5 Protein GLR-5 0.018
ser-3 Protein SER-3 0.017
egl-18 Protein EGL-18 0.016
pptr-2 Protein PPTR-2 0.016
frm-4 Protein FRM-4 0.015
Y44E3A.6 Protein Y44E3A.6 0.015
cat-2 Protein CAT-2 0.014
eea-1 Protein EEA-1 0.014
nrde-3 Protein NRDE-3 0.014
flh-2 Protein FLH-2 0.013
par-5 Protein PAR-5 0.013
cat-1 Protein CAT-1 0.012
frm-10 Protein FRM-10 0.012
sta-1 Protein STA-1 0.012
pqe-1 Protein PQE-1 0.012
psf-1 Protein PSF-1 0.012
K10D6.4 Protein K10D6.4 0.012
prg-2 Protein PRG-2 0.012
bec-1 Protein BEC-1 0.012
sel-2 Protein SEL-2 0.011
let-60 Protein LET-60 0.011
clp-2 Protein CLP-2 0.011
C09F5.1 Protein C09F5.1 0.011
ZC328.3 Protein ZC328.3 0.011
lin-25 Protein LIN-25 0.011
sek-1 Protein SEK-1 0.010
cam-1 Protein CAM-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
ef1a elongation factor 1-alpha 0.705
pdcd2 programmed cell death 2 0.456
chuk conserved helix-loop-helix ubiquitous kinase 0.301
mpx myeloid-specific peroxidase 0.218
cyt1 type I cytokeratin, enveloping layer 0.215
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.185
epas1b endothelial PAS domain protein 1b 0.181
cp ceruloplasmin 0.180
mmp9 matrix metalloproteinase 9 0.167
ripk2 receptor-interacting serine-threonine kinase 2 0.141
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.138
nod1 nucleotide-binding oligomerization domain containing 1 0.112
pcsk2 proprotein convertase subtilisin/kexin type 2 0.106
nanos3 nanos homolog 3 0.100
LOC557072 caspase recruitment domain-containing protein 11-like 0.100
ip6k2 inositol hexaphosphate kinase 2 0.099
lpp LIM domain containing preferred translocation partner in lipoma 0.098
pglyrp5 peptidoglycan recognition protein 5 0.098
tlr9 toll-like receptor 9 0.096
rbp4 retinol binding protein 4, plasma 0.094
stc1l stanniocalcin 1, like 0.090
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.089
adrb2a adrenergic receptor, beta 2a 0.081
tagln2 transgelin 2 0.080
fgfr3 fibroblast growth factor receptor 3 0.078
fabp11a fatty acid binding protein 11a 0.072
epor erythropoietin receptor 0.071
il8 interleukin 8 0.068
igf1ra insulin-like growth factor 1a receptor 0.066
fn1 fibronectin 1 0.062
cry1a cryptochrome 1a 0.062
gngt1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.061
pcsk9 proprotein convertase subtilisin/kexin type 9 0.061
axin2 axin 2 (conductin, axil) 0.060
tlr21 toll-like receptor 21 0.056
tgm2b transglutaminase 2b 0.056
mcoln1 mucolipin 1 0.055
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.054
sh3gl1b SH3-domain GRB2-like 1b 0.054
pycard PYD and CARD domain containing 0.052
rhag Rhesus blood group-associated glycoprotein 0.052
atf3 activating transcription factor 3 0.050
efnb3b ephrin B3b 0.050
ctsl1a cathepsin L, 1 a 0.048
rhcgb Rhesus blood group, C glycoprotein b 0.043
smc1al structural maintenance of chromosomes 1A, like 0.043
gcm2 glial cells missing homolog 2 (Drosophila) 0.042
alp alkaline phosphatase 0.041
bhmt betaine-homocysteine methyltransferase 0.041
cps1 carbamoyl-phosphate synthase 1, mitochondrial 0.040
lyz lysozyme 0.037
mtp microsomal triglyceride transfer protein 0.037
foxi3b forkhead box I3b 0.036
ctsba cathepsin B, a 0.035
LOC100000934 hypothetical protein LOC100000934 0.034
avpl arginine vasopressin-like 0.034
mmp13a matrix metalloproteinase 13a 0.034
il6r interleukin 6 receptor 0.033
tnfb tumor necrosis factor b (TNF superfamily, member 2) 0.032
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.032
msi1 musashi homolog 1 (Drosophila) 0.032
ptger4b prostaglandin E receptor 4 (subtype EP4) b 0.032
psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.032
vasa vasa homolog 0.031
plg plasminogen 0.031
copg2 coatomer protein complex, subunit gamma 2 0.031
si:dkey-76b14.4 si:dkey-76b14.4 0.031
caspa caspase a 0.030
ptgs1 prostaglandin-endoperoxide synthase 1 0.029
zgc:171802 zgc:171802 0.029
junb jun B proto-oncogene 0.029
il1b interleukin 1, beta and interleukin 1, beta 0.028
pglyrp6 peptidoglycan recognition protein 6 0.028
oprk1 opioid receptor, kappa 1 0.028
rel v-rel reticuloendotheliosis viral oncogene homolog 0.027
tlr4bb toll-like receptor 4b, duplicate b 0.027
arrb2b arrestin, beta 2b 0.027
sp2 sp2 transcription factor 0.026
setd7 SET domain containing (lysine methyltransferase) 7 0.025
c1qb complement component 1, q subcomponent, B chain 0.025
spry4 sprouty (Drosophila) homolog 4 0.025
serpinb1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.024
tbx1 T-box 1 0.024
rpl37 ribosomal protein L37 0.024
npy7r neuropeptide Y receptor Y7 0.024
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.024
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.024
fn1b fibronectin 1b 0.024
cd40lg CD40 ligand 0.023
zgc:123282 zgc:123282 0.023
dab1a disabled homolog 1a (Drosophila) 0.023
bhlhe40 basic helix-loop-helix family, member e40 0.022
prkcz protein kinase C, zeta 0.022
si:ch211-195h23.3 si:ch211-195h23.3 0.022
bmp2b bone morphogenetic protein 2b 0.022
si:ch1073-351m12.1 si:ch1073-351m12.1 0.022
gata5 GATA-binding protein 5 0.022
LOC566708 FL cytokine receptor-like 0.022
wls wntless homolog (Drosophila) 0.022
tlr18 toll-like receptor 18 0.022
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Rel Relish 0.995
AttA Attacin-A 0.990
PGRP-LC Peptidoglycan recognition protein LC 0.982
DptB Diptericin B 0.971
PGRP-SA Peptidoglycan recognition protein SA 0.951
grass Gram-positive Specific Serine protease 0.902
spz spatzle 0.865
Spn27A Serpin 27A 0.864
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.850
Atg1 Autophagy-specific gene 1 0.828
CycE Cyclin E 0.811
cact cactus 0.796
CG6361 CG6361 gene product from transcript CG6361-RA 0.753
Sp7 Serine protease 7 0.749
fon fondue 0.689
Mtk Metchnikowin 0.654
BG4 CG12297 gene product from transcript CG12297-RA 0.645
Timp Tissue inhibitor of metalloproteases 0.643
egr eiger 0.635
Dredd Death related ced-3/Nedd2-like protein 0.582
Mpk2 CG5475 gene product from transcript CG5475-RB 0.568
EcR Ecdysone receptor 0.559
Hsf Heat shock factor 0.546
SPE Spatzle-Processing Enzyme 0.541
rl rolled 0.511
LysD Lysozyme D 0.484
key kenny 0.468
LysE Lysozyme E 0.439
CG13422 CG13422 gene product from transcript CG13422-RA 0.438
CG15917 CG15917 gene product from transcript CG15917-RA 0.436
rev7 CG2948 gene product from transcript CG2948-RA 0.421
imd immune deficiency 0.416
osk oskar 0.404
ird5 immune response deficient 5 0.401
PGRP-LF Peptidoglycan recognition protein LF 0.381
CG40127 CG40127 gene product from transcript CG40127-RA 0.377
stumps CG31317 gene product from transcript CG31317-RC 0.368
dco discs overgrown 0.366
foxo forkhead box, sub-group O 0.341
Med Medea 0.338
Irc Immune-regulated catalase 0.325
CG15065 CG15065 gene product from transcript CG15065-RA 0.320
Egfr Epidermal growth factor receptor 0.316
modSP modular serine protease 0.305
brat brain tumor 0.300
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.299
CG32185 CG32185 gene product from transcript CG32185-RA 0.287
Spn1 Serine protease inhibitor 1 0.283
PGRP-LB Peptidoglycan recognition protein LB 0.283
Nrx-IV Neurexin IV 0.281
TM9SF4 CG7364 gene product from transcript CG7364-RA 0.276
Traf4 TNF-receptor-associated factor 4 0.267
Mmp1 Matrix metalloproteinase 1 0.265
CG16718 CG16718 gene product from transcript CG16718-RA 0.260
Myd88 CG2078 gene product from transcript CG2078-RA 0.259
th thread 0.258
Stam Signal transducing adaptor molecule 0.256
Glt Glutactin 0.248
Trx-2 thioredoxin-2 0.245
Top2 Topoisomerase 2 0.238
pirk poor Imd response upon knock-in 0.233
CG31038 CG31038 gene product from transcript CG31038-RA 0.233
mael maelstrom 0.230
Spn28D Serpin 28D 0.228
lwr lesswright 0.225
PGRP-SC2 CG14745 gene product from transcript CG14745-RA 0.225
IM18 Immune induced molecule 18 0.213
IM10 Immune induced molecule 10 0.209
Rbp6 RNA-binding protein 6 0.208
CG9014 CG9014 gene product from transcript CG9014-RA 0.207
sax saxophone 0.204
ovo CG6824 gene product from transcript CG6824-RE 0.203
CG2199 CG2199 gene product from transcript CG2199-RB 0.202
GNBP3 Gram-negative bacteria binding protein 3 0.200
tub tube 0.196
CG18666 CG18666 gene product from transcript CG18666-RA 0.195
CG42863 CG42863 gene product from transcript CG42863-RB 0.195
beta'Cop beta'-coatomer protein 0.193
LysB Lysozyme B 0.193
baz bazooka 0.192
Dpt Diptericin 0.190
Drs Drosomycin 0.188
Cat Catalase 0.186
CG7910 CG7910 gene product from transcript CG7910-RA 0.185
ird1 immune response deficient 1 0.183
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.181
wg wingless 0.180
AttC Attacin-C 0.179
koi klaroid 0.177
Thor CG8846 gene product from transcript CG8846-RA 0.171
eater CG6124 gene product from transcript CG6124-RB 0.171
Dcr-2 Dicer-2 0.169
mbc myoblast city 0.167
pan pangolin 0.167
Ptp69D Protein tyrosine phosphatase 69D 0.165
Rho1 CG8416 gene product from transcript CG8416-RB 0.163
LysC Lysozyme C 0.163
CG18594 CG18594 gene product from transcript CG18594-RA 0.163
pum pumilio 0.162
CG5794 CG5794 gene product from transcript CG5794-RB 0.162
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.999
MYD88 myeloid differentiation primary response gene (88) 0.999
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.999
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.995
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.994
IRAK1 interleukin-1 receptor-associated kinase 1 0.993
TRAF6 TNF receptor-associated factor 6 0.991
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.988
IL8 interleukin 8 0.965
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.961
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.960
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.956
B2M beta-2-microglobulin 0.951
S100B S100 calcium binding protein B 0.941
IL1B interleukin 1, beta 0.937
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.935
ICAM1 intercellular adhesion molecule 1 0.933
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.933
CXCL2 chemokine (C-X-C motif) ligand 2 0.929
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 0.929
UBC ubiquitin C 0.927
ESR1 estrogen receptor 1 0.916
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.916
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.897
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.891
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.891
SMAD4 SMAD family member 4 0.888
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.886
GHR growth hormone receptor 0.873
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.861
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.853
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.842
BIRC3 baculoviral IAP repeat containing 3 0.833
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1 0.831
CXCL3 chemokine (C-X-C motif) ligand 3 0.830
CXCL10 chemokine (C-X-C motif) ligand 10 0.829
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.826
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.815
IFI44 interferon-induced protein 44 0.799
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.788
C1S complement component 1, s subcomponent 0.783
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.781
SOCS3 suppressor of cytokine signaling 3 0.778
TLR2 toll-like receptor 2 0.775
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.773
RIPK2 receptor-interacting serine-threonine kinase 2 0.767
BCL3 B-cell CLL/lymphoma 3 0.745
HLA-A major histocompatibility complex, class I, A 0.745
PLAUR plasminogen activator, urokinase receptor 0.744
NCOR2 nuclear receptor corepressor 2 0.740
TNF tumor necrosis factor 0.735
HLA-B major histocompatibility complex, class I, B 0.732
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.730
S100A9 S100 calcium binding protein A9 0.729
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 0.720
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.716
IFIH1 interferon induced with helicase C domain 1 0.714
HCK hemopoietic cell kinase 0.713
TRIM22 tripartite motif containing 22 0.710
S100A8 S100 calcium binding protein A8 0.707
SQSTM1 sequestosome 1 0.685
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.680
PTAFR platelet-activating factor receptor 0.678
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.671
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.669
FGF1 fibroblast growth factor 1 (acidic) 0.666
HLA-C major histocompatibility complex, class I, C 0.657
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.654
MED15 mediator complex subunit 15 0.654
S100A6 S100 calcium binding protein A6 0.653
CD14 CD14 molecule 0.652
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.645
CCR1 chemokine (C-C motif) receptor 1 0.643
CHUK conserved helix-loop-helix ubiquitous kinase 0.639
DICER1 dicer 1, ribonuclease type III 0.634
IRF7 interferon regulatory factor 7 0.627
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.625
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.614
PYCARD PYD and CARD domain containing 0.613
CCL5 chemokine (C-C motif) ligand 5 0.601
CCL4 chemokine (C-C motif) ligand 4 0.598
MAPK1 mitogen-activated protein kinase 1 0.592
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.590
STAT1 signal transducer and activator of transcription 1, 91kDa 0.588
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.588
RXRA retinoid X receptor, alpha 0.582
IRF1 interferon regulatory factor 1 0.579
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.551
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.550
HLA-DMA major histocompatibility complex, class II, DM alpha 0.548
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.544
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.529
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.527
MAPK14 mitogen-activated protein kinase 14 0.524
PML promyelocytic leukemia 0.522
PLSCR1 phospholipid scramblase 1 0.521
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.520
OAS1 2',5'-oligoadenylate synthetase 1, 40/46kDa 0.517
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Il1b interleukin 1 beta 0.351
Tlr4 toll-like receptor 4 0.327
S100a9 S100 calcium binding protein A9 0.312
Cd38 CD38 molecule 0.308
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.252
Ednra endothelin receptor type A 0.228
Iapp islet amyloid polypeptide 0.226
Pzp pregnancy-zone protein 0.225
Il8rb interleukin 8 receptor, beta 0.211
Hes2 hairy and enhancer of split 2 (Drosophila) 0.209
Csf1 colony stimulating factor 1 (macrophage) 0.190
Ccr2 chemokine (C-C motif) receptor 2 0.183
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.164
S100a8 S100 calcium binding protein A8 0.164
Hoxa2 homeo box A2 0.162
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.159
RT1-EC2 RT1 class Ib, locus EC2 0.151
Ptafr platelet-activating factor receptor 0.151
LOC100363783 rCG53773-like 0.150
St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.139
Igsf6 immunoglobulin superfamily, member 6 0.133
Ncr1 natural cytotoxicity triggering receptor 1 0.133
Cd14 CD14 molecule 0.124
Il1rn interleukin 1 receptor antagonist 0.124
Met met proto-oncogene 0.123
Cd8a CD8a molecule 0.122
Ccl4 chemokine (C-C motif) ligand 4 0.121
Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 0.121
Adora2a adenosine A2a receptor 0.120
Vom2r27 vomeronasal 2 receptor, 27 0.119
Ccl3 chemokine (C-C motif) ligand 3 0.117
Scn11a sodium channel, voltage-gated, type XI, alpha 0.116
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.115
Cxcl2 chemokine (C-X-C motif) ligand 2 0.114
Calcrl calcitonin receptor-like 0.113
Gzmb granzyme B 0.112
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.110
Il6 interleukin 6 0.105
RGD1559588 similar to cell surface receptor FDFACT 0.105
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.104
Cd86 CD86 molecule 0.103
Havcr1 hepatitis A virus cellular receptor 1 0.097
Aif1 allograft inflammatory factor 1 0.095
Oas1a 2'-5' oligoadenylate synthetase 1A 0.091
Il1r1 interleukin 1 receptor, type I 0.091
Trim47 tripartite motif-containing 47 0.091
Aqp8 aquaporin 8 0.088
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.087
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.086
Pdyn prodynorphin 0.085
Ltbr lymphotoxin beta receptor (TNFR superfamily, member 3) 0.085
Fosl1 fos-like antigen 1 0.081
Sell selectin L 0.080
Flt1 FMS-related tyrosine kinase 1 0.080
Fgfr2 fibroblast growth factor receptor 2 0.078
RGD1306474 similar to RIKEN cDNA 9530003J23 0.077
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.076
Dgkg diacylglycerol kinase, gamma 0.076
Apoa5 apolipoprotein A-V 0.076
Gstm3 glutathione S-transferase mu 3 0.075
Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 0.074
Il4 interleukin 4 0.072
Cd5 Cd5 molecule 0.072
Edn1 endothelin 1 0.072
Ccr1 chemokine (C-C motif) receptor 1 0.072
Cfb complement factor B 0.070
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.070
Mmp12 matrix metallopeptidase 12 0.069
Olr226 olfactory receptor 226 0.069
Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 0.069
Mmp3 matrix metallopeptidase 3 0.068
S1pr2 sphingosine-1-phosphate receptor 2 0.068
Bst1 bone marrow stromal cell antigen 1 0.067
Fam70b family with sequence similarity 70, member B 0.067
Csf3r colony stimulating factor 3 receptor (granulocyte) 0.067
Cckar cholecystokinin A receptor 0.067
Prf1 perforin 1 (pore forming protein) 0.066
Adam7 ADAM metallopeptidase domain 7 0.066
Stip1 stress-induced phosphoprotein 1 0.065
Lpl lipoprotein lipase 0.065
Tfec transcription factor EC 0.063
Clec4f C-type lectin domain family 4, member f 0.063
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.063
Faslg Fas ligand (TNF superfamily, member 6) 0.062
Crhbp corticotropin releasing hormone binding protein 0.061
Ptpre protein tyrosine phosphatase, receptor type, E 0.061
Tgm1 transglutaminase 1, K polypeptide 0.061
Cd2 Cd2 molecule 0.059
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.058
Oprm1 opioid receptor, mu 1 0.058
Padi1 peptidyl arginine deiminase, type I 0.058
Adra1b adrenergic, alpha-1B-, receptor 0.057
Cfi complement factor I 0.057
Lcn2 lipocalin 2 0.056
C1r complement component 1, r subcomponent 0.056
Rgs1 regulator of G-protein signaling 1 0.056
Rod1 ROD1 regulator of differentiation 1 (S. pombe) 0.056
Gpx3 glutathione peroxidase 3 0.056
Olr1496 olfactory receptor 1496 0.056
Zfp36 zinc finger protein 36 0.055
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism